TW218025B - - Google Patents

Info

Publication number
TW218025B
TW218025B TW080106046A TW80106046A TW218025B TW 218025 B TW218025 B TW 218025B TW 080106046 A TW080106046 A TW 080106046A TW 80106046 A TW80106046 A TW 80106046A TW 218025 B TW218025 B TW 218025B
Authority
TW
Taiwan
Application number
TW080106046A
Other languages
Chinese (zh)
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909016882A external-priority patent/GB9016882D0/en
Priority claimed from GB909016840A external-priority patent/GB9016840D0/en
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Application granted granted Critical
Publication of TW218025B publication Critical patent/TW218025B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08—Lactones or lactides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/88—Post-polymerisation treatment
    • C08G63/90—Purification; Drying

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW080106046A 1990-08-01 1991-08-02 TW218025B (en:Method)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909016882A GB9016882D0 (en) 1990-08-01 1990-08-01 Improvements in or relating to organic compounds
GB909016840A GB9016840D0 (en) 1990-08-01 1990-08-01 Improvements in or relating to organic compounds

Publications (1)

Publication Number Publication Date
TW218025B true TW218025B (en:Method) 1993-12-21

Family

ID=26297417

Family Applications (2)

Application Number Title Priority Date Filing Date
TW082100731A TW282477B (en:Method) 1990-08-01 1991-08-02
TW080106046A TW218025B (en:Method) 1990-08-01 1991-08-02

Family Applications Before (1)

Application Number Title Priority Date Filing Date
TW082100731A TW282477B (en:Method) 1990-08-01 1991-08-02

Country Status (27)

Country Link
EP (2) EP0816413B1 (en:Method)
JP (1) JP3137368B2 (en:Method)
KR (1) KR100255904B1 (en:Method)
AT (1) AT402503B (en:Method)
AU (1) AU650277B2 (en:Method)
CA (1) CA2048200C (en:Method)
CH (1) CH683772A5 (en:Method)
CY (1) CY1986A (en:Method)
DE (1) DE4124468B4 (en:Method)
DK (2) DK0469520T3 (en:Method)
ES (2) ES2243966T3 (en:Method)
FI (2) FI108040B (en:Method)
FR (1) FR2665453B1 (en:Method)
GB (1) GB2246573B (en:Method)
GR (1) GR3026322T3 (en:Method)
HK (1) HK11797A (en:Method)
HU (1) HUT59837A (en:Method)
IE (1) IE66185B1 (en:Method)
IL (1) IL99007A (en:Method)
IT (1) IT1252944B (en:Method)
LU (1) LU87985A1 (en:Method)
MY (1) MY108621A (en:Method)
NO (1) NO912960D0 (en:Method)
NZ (1) NZ239184A (en:Method)
PH (1) PH31047A (en:Method)
PT (1) PT98491B (en:Method)
TW (2) TW282477B (en:Method)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5560929A (en) * 1986-08-18 1996-10-01 The Dow Chemical Company Structured copolymers and their use as absorbents, gels and carriers of metal ions
US5527524A (en) * 1986-08-18 1996-06-18 The Dow Chemical Company Dense star polymer conjugates
US5225521A (en) * 1991-12-31 1993-07-06 E. I. Du Pont De Nemours And Company Star-shaped hydroxyacid polymers
US6200558B1 (en) 1993-09-14 2001-03-13 The United States Of America As Represented By The Department Of Health And Human Services Biopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
US5405919A (en) * 1992-08-24 1995-04-11 The United States Of America As Represented By The Secretary Of Health And Human Services Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disorders
US5525357A (en) * 1992-08-24 1996-06-11 The United States Of America As Represented By The Department Of Health And Human Services Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
JPH06116381A (ja) * 1992-10-09 1994-04-26 Mitsui Toatsu Chem Inc ポリヒドロキシカルボン酸の精製方法
DE4412317A1 (de) * 1993-04-21 1994-10-27 Basf Ag Polylactid mit verbreiterter Molmassenverteilung
US5359026A (en) * 1993-07-30 1994-10-25 Cargill, Incorporated Poly(lactide) copolymer and process for manufacture thereof
US5496923A (en) * 1993-09-20 1996-03-05 Mitsui Toatsu Chemicals, Inc. Purification process of aliphatic polyester
NZ276088A (en) 1993-11-19 1999-07-29 Janssen Pharmaceutica Nv [(1,2-benzisoxazol-3-yl)-1-piperidinyl-alkyl-6,7,8,9-tetrahydro-4h- pyrido[1,2-a]-pyrimidin-4-one derivatives (ie risperidone)
IL128774A (en) * 1994-03-07 2001-05-20 Dow Chemical Co Composition comprising a dendritic poymer in complex with at least one unit of biological response modifier and a process for the preparation thereof
AU5862199A (en) 1998-09-11 2000-04-03 Michael Raschke Biologically active implants
US6362308B1 (en) * 2000-08-10 2002-03-26 Alkermes Controlled Therapeutics Inc. Ii Acid end group poly(d,l-lactide-co-glycolide) copolymers high glycolide content
WO2003006525A1 (en) * 2001-07-10 2003-01-23 Kureha Chemical Industry Company, Limited Polyhydroxycarboxylic acid and its production process
AU2002358831B2 (en) 2001-10-10 2007-09-06 Pierre Fabre Medicament Prolonged release biodegradable microspheres and method for preparing same
FR2830448B1 (fr) * 2001-10-10 2004-03-19 Pf Medicament Microspheres biodegradables a liberation prolongee et leur procede de preparation
GB0226993D0 (en) * 2002-11-19 2002-12-24 Novartis Ag Organic compounds
AU2013204972B2 (en) * 2002-11-19 2016-04-21 Novartis Ag Pharmaceutical composition comprising octreotide microparticles
US20040097419A1 (en) * 2002-11-19 2004-05-20 Holger Petersen Organic compounds
ES2383303T3 (es) 2005-11-10 2012-06-20 Chemi S.P.A. Formulaciones de inhibidores de la liberación prolongada de la hormona del crecimiento análogos de la somatostatina
CN101193531B (zh) 2006-11-29 2010-12-01 富准精密工业(深圳)有限公司 散热装置
WO2009091150A2 (en) * 2007-12-31 2009-07-23 Samyang Corporation Highly pure amphiphilic copolymer comprising hydrophobic block from alpha-hydroxy acid and process for the preparation thereof
CA2756388C (en) * 2009-03-23 2015-10-27 Micell Technologies, Inc. Biodegradable polymers with low acidic impurity
JP5594996B2 (ja) 2009-09-14 2014-09-24 三菱重工業株式会社 航空機の操縦システム
US8722845B2 (en) 2010-06-21 2014-05-13 Lg Chem, Ltd. Polylactide resin having excellent heat resistance and preparation method thereof
EP2455414A1 (de) * 2010-11-17 2012-05-23 Evonik Röhm GmbH Verfahren zur Herstellung von hochmolekularen, resorbierbaren Polyestern, die mit dem Verfahren herstellbaren hochmolekularen resorbierbaren Polyester und deren Verwendung
EP2455415A1 (de) * 2010-11-17 2012-05-23 Evonik Röhm GmbH Verfahren zur Herstellung von niedermolekularen, resorbierbaren Polyestern, die mit dem Verfahren herstellbaren niedermolekularen resorbierbaren Polyester und deren Verwendung
CN105820332B (zh) * 2015-01-09 2018-06-29 北京化工大学 一种星形聚氨基酸和星形聚氨基酸载药纳米胶束及制备方法
EP3408305B1 (en) 2016-01-29 2024-03-06 Tolmar Inc. Purification and decolorization of polymers
CA3073842A1 (en) * 2017-08-31 2019-03-07 Evonik Corporation Improved resorbable polymer purification process
GR1009392B (el) * 2017-09-19 2018-10-25 Φαρματεν Αβεε Φαρμακευτικο σκευασμα που περιλαμβανει ενα πεπτιδικο φαρμακο και μεθοδος για την παρασκευη αυτου
GB2568526A (en) * 2017-11-20 2019-05-22 Rebio Tech Oy Composition
CN112940234B (zh) * 2021-01-28 2022-05-03 广东粤港澳大湾区黄埔材料研究院 一种高纯度聚乙丙交酯的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1467970A (en) * 1975-05-02 1977-03-23 Ici Ltd Purification of polyethers
US4273920A (en) * 1979-09-12 1981-06-16 Eli Lilly And Company Polymerization process and product
CH656884A5 (de) * 1983-08-26 1986-07-31 Sandoz Ag Polyolester, deren herstellung und verwendung.
CA1256638A (en) * 1984-07-06 1989-06-27 Motoaki Tanaka Polymer and its production
US4677231A (en) * 1984-11-13 1987-06-30 Asahi Kasei Kogyo Kabushiki Kaisha Process for purification of polyether
JP2551756B2 (ja) * 1985-05-07 1996-11-06 武田薬品工業株式会社 ポリオキシカルボン酸エステルおよびその製造法
JPH0610252B2 (ja) * 1985-08-21 1994-02-09 和光純薬工業株式会社 重合体の製造法
DE3641692A1 (de) * 1986-12-06 1988-06-09 Boehringer Ingelheim Kg Katalysatorfreie resorbierbare homopolymere und copolymere
DE3708916A1 (de) * 1987-03-19 1988-09-29 Boehringer Ingelheim Kg Verfahren zur reinigung resorbierbarer polyester
JP2714454B2 (ja) * 1988-11-07 1998-02-16 三井東圧化学株式会社 生体吸収性ポリエステルの製造方法
CA2040141C (en) * 1990-04-13 2002-05-14 Minoru Yamada Biodegradable high-molecular polymers, production and use therof

Also Published As

Publication number Publication date
EP0469520B1 (en) 1998-02-25
FR2665453A1 (fr) 1992-02-07
DE4124468A1 (de) 1992-02-06
PT98491A (pt) 1992-06-30
FI913641A0 (fi) 1991-07-30
ATA151591A (de) 1996-10-15
CY1986A (en) 1997-09-05
JPH0641279A (ja) 1994-02-15
PT98491B (pt) 1997-12-31
CA2048200C (en) 1999-06-29
GB9116396D0 (en) 1991-09-11
ITRM910553A0 (it) 1991-07-23
EP0816413B1 (en) 2005-06-08
HK11797A (en) 1997-02-14
AU8143091A (en) 1992-02-27
AT402503B (de) 1997-06-25
NO912960D0 (no) 1991-07-30
IL99007A (en) 1994-12-29
KR920003990A (ko) 1992-03-27
MY108621A (en) 1996-10-31
PH31047A (en) 1998-02-03
ES2112259T3 (es) 1998-04-01
IT1252944B (it) 1995-07-05
JP3137368B2 (ja) 2001-02-19
IL99007A0 (en) 1992-07-15
FR2665453B1 (fr) 1995-01-27
GB2246573B (en) 1994-05-11
GB2246573A (en) 1992-02-05
AU650277B2 (en) 1994-06-16
DK0469520T3 (da) 1998-09-23
KR100255904B1 (ko) 2000-05-01
GR3026322T3 (en) 1998-06-30
TW282477B (en:Method) 1996-08-01
EP0469520A2 (en) 1992-02-05
FI913641L (fi) 1992-02-02
HUT59837A (en) 1992-07-28
FI111268B (fi) 2003-06-30
DK0816413T3 (da) 2005-08-29
NZ239184A (en) 1994-09-27
EP0469520A3 (en) 1992-10-07
EP0816413A3 (en) 1998-11-11
ES2243966T3 (es) 2005-12-01
DE4124468B4 (de) 2010-10-28
IE912697A1 (en) 1992-02-12
FI20011189L (fi) 2001-06-05
CA2048200A1 (en) 1992-02-02
IE66185B1 (en) 1995-12-13
HU912452D0 (en) 1991-12-30
EP0816413A2 (en) 1998-01-07
ITRM910553A1 (it) 1993-01-23
CH683772A5 (de) 1994-05-13
FI108040B (fi) 2001-11-15
LU87985A1 (fr) 1993-02-15

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Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees