TW202432837A - 用以改良細胞培養效能及減少天冬醯胺序列變異之天冬醯胺饋料策略 - Google Patents
用以改良細胞培養效能及減少天冬醯胺序列變異之天冬醯胺饋料策略 Download PDFInfo
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- TW202432837A TW202432837A TW113117120A TW113117120A TW202432837A TW 202432837 A TW202432837 A TW 202432837A TW 113117120 A TW113117120 A TW 113117120A TW 113117120 A TW113117120 A TW 113117120A TW 202432837 A TW202432837 A TW 202432837A
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- Prior art keywords
- asparagine
- cell culture
- cell
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- fed
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
- C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/04—Preserving or maintaining viable microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/20—Aspartic acid; Asparagine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Reproductive Health (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063072740P | 2020-08-31 | 2020-08-31 | |
| US202063072745P | 2020-08-31 | 2020-08-31 | |
| US63/072,745 | 2020-08-31 | ||
| US63/072,740 | 2020-08-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW202432837A true TW202432837A (zh) | 2024-08-16 |
Family
ID=78073988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW113117120A TW202432837A (zh) | 2020-08-31 | 2021-08-27 | 用以改良細胞培養效能及減少天冬醯胺序列變異之天冬醯胺饋料策略 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US12163122B2 (enExample) |
| EP (1) | EP4204578A1 (enExample) |
| JP (1) | JP2023542820A (enExample) |
| KR (1) | KR20230058094A (enExample) |
| CN (1) | CN116209772A (enExample) |
| AU (1) | AU2021332355A1 (enExample) |
| BR (1) | BR112023003273A2 (enExample) |
| CA (1) | CA3192999A1 (enExample) |
| CL (1) | CL2023000576A1 (enExample) |
| CO (1) | CO2023003662A2 (enExample) |
| IL (1) | IL300828A (enExample) |
| MX (1) | MX2023002417A (enExample) |
| TW (1) | TW202432837A (enExample) |
| WO (1) | WO2022047108A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114901794B (zh) | 2019-11-15 | 2026-05-01 | 隆萨有限公司 | 用于生产接种物的过程和系统 |
| CN114836367A (zh) * | 2022-04-28 | 2022-08-02 | 上海东富龙生物试剂有限公司 | 用于hek293细胞培养及腺病毒、腺相关病毒复制扩增的化学成分限定培养基 |
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| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| FR2543158B1 (fr) | 1983-03-24 | 1985-11-15 | Inst Nat Sante Rech Med | Milieu de culture de cellules animales sans serum, sans hormones et sans facteurs de croissance et procedes de culture primaire et d'obtention de lignees cellulaires utilisant ce milieu |
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-
2021
- 2021-08-27 IL IL300828A patent/IL300828A/en unknown
- 2021-08-27 EP EP21786285.3A patent/EP4204578A1/en active Pending
- 2021-08-27 BR BR112023003273A patent/BR112023003273A2/pt unknown
- 2021-08-27 KR KR1020237009931A patent/KR20230058094A/ko active Pending
- 2021-08-27 MX MX2023002417A patent/MX2023002417A/es unknown
- 2021-08-27 CN CN202180063115.3A patent/CN116209772A/zh active Pending
- 2021-08-27 US US17/458,929 patent/US12163122B2/en active Active
- 2021-08-27 TW TW113117120A patent/TW202432837A/zh unknown
- 2021-08-27 JP JP2023513579A patent/JP2023542820A/ja active Pending
- 2021-08-27 AU AU2021332355A patent/AU2021332355A1/en active Pending
- 2021-08-27 WO PCT/US2021/047870 patent/WO2022047108A1/en not_active Ceased
- 2021-08-27 CA CA3192999A patent/CA3192999A1/en active Pending
-
2023
- 2023-02-28 CL CL2023000576A patent/CL2023000576A1/es unknown
- 2023-03-23 CO CONC2023/0003662A patent/CO2023003662A2/es unknown
-
2024
- 2024-11-08 US US18/942,224 patent/US20250066718A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022047108A1 (en) | 2022-03-03 |
| BR112023003273A2 (pt) | 2023-05-02 |
| IL300828A (en) | 2023-04-01 |
| CA3192999A1 (en) | 2022-03-03 |
| MX2023002417A (es) | 2023-03-22 |
| US12163122B2 (en) | 2024-12-10 |
| US20250066718A1 (en) | 2025-02-27 |
| JP2023542820A (ja) | 2023-10-12 |
| CL2023000576A1 (es) | 2023-09-29 |
| CO2023003662A2 (es) | 2023-04-05 |
| EP4204578A1 (en) | 2023-07-05 |
| US20220064591A1 (en) | 2022-03-03 |
| KR20230058094A (ko) | 2023-05-02 |
| TW202225398A (zh) | 2022-07-01 |
| AU2021332355A1 (en) | 2023-03-23 |
| CN116209772A (zh) | 2023-06-02 |
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