TW202342741A - 多胜肽及使用其之胺基酸的製造方法 - Google Patents

多胜肽及使用其之胺基酸的製造方法 Download PDF

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Publication number
TW202342741A
TW202342741A TW111149813A TW111149813A TW202342741A TW 202342741 A TW202342741 A TW 202342741A TW 111149813 A TW111149813 A TW 111149813A TW 111149813 A TW111149813 A TW 111149813A TW 202342741 A TW202342741 A TW 202342741A
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Taiwan
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group
amino acid
residue
sequence
represented
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TW111149813A
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English (en)
Chinese (zh)
Inventor
篠田清道
太田淳
椎名淳一
松尾篤
石野聡
江島大貴
石山詩織
中野効彦
塚田啓介
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日商中外製藥股份有限公司
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Application filed by 日商中外製藥股份有限公司 filed Critical 日商中外製藥股份有限公司
Priority to EP23803626.3A priority Critical patent/EP4520748A1/en
Priority to KR1020247040257A priority patent/KR20250011913A/ko
Priority to JP2024520494A priority patent/JPWO2023219152A1/ja
Priority to US18/864,039 priority patent/US20250369029A1/en
Priority to JP2024520496A priority patent/JPWO2023219156A1/ja
Priority to KR1020247040256A priority patent/KR20250012580A/ko
Priority to PCT/JP2023/017844 priority patent/WO2023219152A1/ja
Priority to EP23803630.5A priority patent/EP4520829A1/en
Priority to US18/864,049 priority patent/US20250368680A1/en
Priority to PCT/JP2023/017861 priority patent/WO2023219156A1/ja
Publication of TW202342741A publication Critical patent/TW202342741A/zh

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0016Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0026Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)
    • C12N9/0028Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5) with NAD or NADP as acceptor (1.5.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y105/00Oxidoreductases acting on the CH-NH group of donors (1.5)
    • C12Y105/01Oxidoreductases acting on the CH-NH group of donors (1.5) with NAD+ or NADP+ as acceptor (1.5.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y104/00Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/01Oxidoreductases acting on the CH-NH2 group of donors (1.4) with NAD+ or NADP+ as acceptor (1.4.1)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
TW111149813A 2021-12-28 2022-12-23 多胜肽及使用其之胺基酸的製造方法 TW202342741A (zh)

Priority Applications (10)

Application Number Priority Date Filing Date Title
EP23803626.3A EP4520748A1 (en) 2022-05-13 2023-05-12 Method for producing salt of amino acid or salt of peptide compound or solvate of either one of said salts comprising lithium salt precipitation step
KR1020247040257A KR20250011913A (ko) 2022-05-13 2023-05-12 효소 및 첨가제를 이용한 아미노산 및 펩타이드 화합물의 생성 방법
JP2024520494A JPWO2023219152A1 (https=) 2022-05-13 2023-05-12
US18/864,039 US20250369029A1 (en) 2022-05-13 2023-05-12 Method for producing amino acid and peptide compound, using enzyme and additive
JP2024520496A JPWO2023219156A1 (https=) 2022-05-13 2023-05-12
KR1020247040256A KR20250012580A (ko) 2022-05-13 2023-05-12 리튬 염 침전 단계를 포함하는, 아미노산의 염 또는 펩타이드 화합물의 염 또는 상기 염 중 하나의 용매화물을 생성하는 방법
PCT/JP2023/017844 WO2023219152A1 (ja) 2022-05-13 2023-05-12 リチウム塩の析出工程を含む、アミノ酸の塩若しくはペプチド化合物の塩又はこれらの溶媒和物の製造方法
EP23803630.5A EP4520829A1 (en) 2022-05-13 2023-05-12 Method for producing amino acid and peptide compound, using enzyme and additive
US18/864,049 US20250368680A1 (en) 2022-05-13 2023-05-12 Method for producing salt of amino acid or salt of peptide compound or solvate of either one of said salts comprising lithium salt precipitation step
PCT/JP2023/017861 WO2023219156A1 (ja) 2022-05-13 2023-05-12 酵素及び添加剤を用いたアミノ酸及びペプチド化合物の製造方法

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP2021215094 2021-12-28
JP2021-215094 2021-12-28
JP2022079712 2022-05-13
JP2022079708 2022-05-13
JP2022079711 2022-05-13
JP2022-079711 2022-05-13
JP2022-079708 2022-05-13
JP2022-079712 2022-05-13

Publications (1)

Publication Number Publication Date
TW202342741A true TW202342741A (zh) 2023-11-01

Family

ID=86558905

Family Applications (1)

Application Number Title Priority Date Filing Date
TW111149813A TW202342741A (zh) 2021-12-28 2022-12-23 多胜肽及使用其之胺基酸的製造方法

Country Status (6)

Country Link
US (1) US20250129398A1 (https=)
EP (1) EP4206322A3 (https=)
JP (1) JPWO2023127752A1 (https=)
KR (1) KR20240128008A (https=)
TW (1) TW202342741A (https=)
WO (1) WO2023127752A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4056580A4 (en) 2019-11-07 2023-12-06 Chugai Seiyaku Kabushiki Kaisha METHOD FOR PRODUCING A PEPTIDE COMPOUND COMPRISING A STERICALLY HINDERED AMINO ACID
US12312379B2 (en) 2021-05-07 2025-05-27 Chugai Seiyaku Kabushiki Kaisha Methods for producing cyclic compounds comprising N-substituted amino acid residues

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002306849A1 (en) 2001-03-21 2002-10-08 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
AU2003211367A1 (en) 2002-02-28 2003-09-09 Mitsubishi Chemical Corporation Novel dehydrogenase and gene encoding the same
JP4590981B2 (ja) * 2003-08-26 2010-12-01 三菱化学株式会社 光学活性環状アミノ酸の製造方法
HUE036947T2 (hu) * 2012-05-11 2018-08-28 Codexis Inc Átalakított iminreduktázok és eljárások keton- és aminvegyületek reduktív aminálására

Also Published As

Publication number Publication date
KR20240128008A (ko) 2024-08-23
US20250129398A1 (en) 2025-04-24
EP4206322A3 (en) 2023-09-06
JPWO2023127752A1 (https=) 2023-07-06
WO2023127752A1 (ja) 2023-07-06
EP4206322A2 (en) 2023-07-05

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