TW202227140A - 抗體-藥物結合物及抗SIRPα抗體之組合 - Google Patents
抗體-藥物結合物及抗SIRPα抗體之組合 Download PDFInfo
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- TW202227140A TW202227140A TW110141798A TW110141798A TW202227140A TW 202227140 A TW202227140 A TW 202227140A TW 110141798 A TW110141798 A TW 110141798A TW 110141798 A TW110141798 A TW 110141798A TW 202227140 A TW202227140 A TW 202227140A
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- C07—ORGANIC CHEMISTRY
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020-188084 | 2020-11-11 | ||
| JP2020188084 | 2020-11-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW202227140A true TW202227140A (zh) | 2022-07-16 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW110141798A TW202227140A (zh) | 2020-11-11 | 2021-11-10 | 抗體-藥物結合物及抗SIRPα抗體之組合 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230414778A1 (https=) |
| EP (1) | EP4245321A4 (https=) |
| JP (1) | JPWO2022102634A1 (https=) |
| KR (1) | KR20230106645A (https=) |
| CN (1) | CN116916919A (https=) |
| AU (1) | AU2021378152A1 (https=) |
| BR (1) | BR112023008845A2 (https=) |
| CA (1) | CA3198330A1 (https=) |
| IL (1) | IL302812A (https=) |
| TW (1) | TW202227140A (https=) |
| WO (1) | WO2022102634A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20250282865A1 (en) * | 2022-05-10 | 2025-09-11 | Daiichi Sankyo Company, Limited | COMBINATION OF ANTIBODY-DRUG CONJUGATE AND ANTI-SIRPa ANTIBODY |
| CN119255825A (zh) * | 2022-05-24 | 2025-01-03 | 第一三共株式会社 | 抗-cdh6抗体-药物缀合物的剂量方案 |
| WO2025002310A1 (zh) * | 2023-06-29 | 2025-01-02 | 石药集团巨石生物制药有限公司 | 抗体-药物偶联物及其用途 |
| CN119454937A (zh) * | 2023-11-13 | 2025-02-18 | 苏州宜联生物医药有限公司 | 抗b7h3抗体-药物偶联物治疗癌症的方法 |
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| JP3101690B2 (ja) | 1987-03-18 | 2000-10-23 | エス・ビィ・2・インコーポレイテッド | 変性抗体の、または変性抗体に関する改良 |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| US5885573A (en) | 1993-06-01 | 1999-03-23 | Arch Development Corporation | Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies |
| AU691811B2 (en) | 1993-06-16 | 1998-05-28 | Celltech Therapeutics Limited | Antibodies |
| DK1071700T3 (da) | 1998-04-20 | 2010-06-07 | Glycart Biotechnology Ag | Glykosylerings-modifikation af antistoffer til forbedring af antistofafhængig cellulær cytotoksicitet |
| CA2704600C (en) | 1999-04-09 | 2016-10-25 | Kyowa Kirin Co., Ltd. | A method for producing antibodies with increased adcc activity |
| CN100340575C (zh) | 1999-06-25 | 2007-10-03 | 杰南技术公司 | 人源化抗ErbB2抗体及其在制备药物中的应用 |
| CA2953239A1 (en) | 2000-10-06 | 2002-04-18 | Kyowa Hakko Kirin Co., Ltd. | Antibody composition-producing cell |
| AR056857A1 (es) | 2005-12-30 | 2007-10-24 | U3 Pharma Ag | Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos |
| WO2007133855A2 (en) | 2006-03-27 | 2007-11-22 | University Of Maryland Biotechnology Institute | Glycoprotein synthesis and remodeling by enzymatic transglycosylation |
| KR101598229B1 (ko) | 2007-02-16 | 2016-02-26 | 메리맥 파마슈티컬즈, 인크. | Erbb3에 대한 항체 및 이의 용도 |
| EP3255060A1 (en) | 2008-12-09 | 2017-12-13 | F. Hoffmann-La Roche AG | Anti-pd-l1 antibodies and their use to enhance t-cell function |
| IN2014DN06806A (https=) | 2012-02-10 | 2015-05-22 | Univ Maryland | |
| ES2773710T3 (es) | 2012-10-11 | 2020-07-14 | Daiichi Sankyo Co Ltd | Enlazadores para conjugados de anticuerpo - fármaco |
| WO2014061277A1 (ja) | 2012-10-19 | 2014-04-24 | 第一三共株式会社 | 親水性構造を含むリンカーで結合させた抗体-薬物コンジュゲート |
| AU2014371934B2 (en) | 2013-12-25 | 2020-01-23 | Daiichi Sankyo Company, Limited | Anti-TROP2 antibody-drug conjugate |
| IL310627B2 (en) | 2014-01-31 | 2026-04-01 | Daiichi Sankyo Co Ltd | Anti-HER2 antibody-drug conjugates, compositions containing them and uses thereof |
| JP2017114763A (ja) | 2014-03-26 | 2017-06-29 | 第一三共株式会社 | 抗cd98抗体−薬物コンジュゲート |
| KR102445502B1 (ko) | 2014-04-10 | 2022-09-21 | 다이이찌 산쿄 가부시키가이샤 | 항her3 항체-약물 콘주게이트 |
| EP3130608B1 (en) | 2014-04-10 | 2019-09-04 | Daiichi Sankyo Co., Ltd. | (anti-her2 antibody)-drug conjugate |
| CN116059395A (zh) | 2015-06-29 | 2023-05-05 | 第一三共株式会社 | 用于选择性制造抗体-药物缀合物的方法 |
| BR112018070823A2 (pt) | 2016-04-14 | 2019-02-05 | Ose Immunotherapeutics | anticorpo sirpa anti-humano ou fragmento de ligação a antígeno do mesmo ou mimético de anticorpo de ligação a antígeno, composição farmacêutica, produto de combinação, molécula de ácido nucleico isolada, vetor, célula hospedeira isolada, polipeptídeo, métodos para fabricar um anticorpo, in vitro ou ex vivo para determinar células positivas para sirpa, de diagnóstico e para prever a resposta de um sujeito, e, uso de um anticorpo anti-sirpa ou um fragmento de ligação a antígeno do mesmo ou um mimético de ligação a anticorpo e in vitro ou ex vivo de pelo menos um anticorpo sirpa anti-humano ou fragmento de ligação a antígeno do mesmo ou mimético de anticorpo de ligação a antígeno. |
| CN109862910A (zh) | 2016-08-03 | 2019-06-07 | 小利兰·斯坦福大学托管委员会 | 破坏巨噬细胞上的Fc受体接合增强抗SIRPα抗体疗法的功效 |
| JP6679762B2 (ja) | 2017-01-17 | 2020-04-15 | 第一三共株式会社 | 抗gpr20抗体及び抗gpr20抗体−薬物コンジュゲート |
| KR102702926B1 (ko) | 2017-04-13 | 2024-09-06 | 사이로파 비.브이. | 항-sirp 알파 항체 |
| TW202532104A (zh) | 2017-05-15 | 2025-08-16 | 日商第一三共股份有限公司 | 抗體-藥物結合物及其用途 |
| IL324591A (en) * | 2017-08-31 | 2026-01-01 | Daiichi Sankyo Co Ltd | Improved antibody-drug conjugate production methods |
| JPWO2019044974A1 (ja) * | 2017-08-31 | 2020-12-03 | 株式会社Veritas In Silico | スモールガイドアンチセンス核酸とその使用 |
| SG11202010496WA (en) * | 2018-05-18 | 2020-12-30 | Daiichi Sankyo Co Ltd | Anti-muc1 antibody-drug conjugate |
| SG11202012338QA (en) * | 2018-07-10 | 2021-01-28 | Univ Kobe Nat Univ Corp | ANTI-SIRPa ANTIBODY |
| SG11202100653YA (en) * | 2018-07-25 | 2021-02-25 | Daiichi Sankyo Co Ltd | Effective method for manufacturing antibody-drug conjugate |
| JP2022512541A (ja) * | 2018-08-29 | 2022-02-07 | シャタック ラボ,インコーポレイテッド | Pd-1系キメラタンパク質を含む併用療法 |
| JP7451520B2 (ja) * | 2018-11-15 | 2024-03-18 | ビョンディス・ビー.ブイ. | ヒト化抗SIRPα抗体 |
-
2021
- 2021-11-10 AU AU2021378152A patent/AU2021378152A1/en active Pending
- 2021-11-10 CA CA3198330A patent/CA3198330A1/en active Pending
- 2021-11-10 WO PCT/JP2021/041255 patent/WO2022102634A1/ja not_active Ceased
- 2021-11-10 TW TW110141798A patent/TW202227140A/zh unknown
- 2021-11-10 US US18/036,289 patent/US20230414778A1/en active Pending
- 2021-11-10 BR BR112023008845A patent/BR112023008845A2/pt unknown
- 2021-11-10 EP EP21891880.3A patent/EP4245321A4/en active Pending
- 2021-11-10 KR KR1020237019043A patent/KR20230106645A/ko active Pending
- 2021-11-10 IL IL302812A patent/IL302812A/en unknown
- 2021-11-10 JP JP2022561950A patent/JPWO2022102634A1/ja active Pending
- 2021-11-10 CN CN202180075998.XA patent/CN116916919A/zh active Pending
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|---|---|
| AU2021378152A1 (en) | 2023-06-22 |
| KR20230106645A (ko) | 2023-07-13 |
| EP4245321A1 (en) | 2023-09-20 |
| JPWO2022102634A1 (https=) | 2022-05-19 |
| BR112023008845A2 (pt) | 2023-10-03 |
| US20230414778A1 (en) | 2023-12-28 |
| IL302812A (en) | 2023-07-01 |
| CA3198330A1 (en) | 2022-05-19 |
| CN116916919A (zh) | 2023-10-20 |
| AU2021378152A9 (en) | 2024-06-20 |
| WO2022102634A1 (ja) | 2022-05-19 |
| EP4245321A4 (en) | 2025-10-01 |
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