TW202122573A - 治療血管疾病之組成物及方法 - Google Patents

治療血管疾病之組成物及方法 Download PDF

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TW202122573A
TW202122573A TW109129322A TW109129322A TW202122573A TW 202122573 A TW202122573 A TW 202122573A TW 109129322 A TW109129322 A TW 109129322A TW 109129322 A TW109129322 A TW 109129322A TW 202122573 A TW202122573 A TW 202122573A
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meso
vpc
cells
mir
hsa
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TW109129322A
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瑪麗亞 米洛祖
奴丹 普拉森
阿姆里塔 辛格
羅伯特 蘭札
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安斯泰來再生醫藥協會
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    • A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
    • A—HUMAN NECESSITIES
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
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    • C12N5/0602—Vertebrate cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

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  • Health & Medical Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
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  • Inorganic Chemistry (AREA)
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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
TW109129322A 2019-08-28 2020-08-27 治療血管疾病之組成物及方法 TW202122573A (zh)

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US201962892724P 2019-08-28 2019-08-28
US62/892,724 2019-08-28

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TW202122573A true TW202122573A (zh) 2021-06-16

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US (1) US20220288131A1 (cg-RX-API-DMAC7.html)
EP (1) EP4022038A1 (cg-RX-API-DMAC7.html)
JP (2) JP7894203B2 (cg-RX-API-DMAC7.html)
KR (1) KR20220049618A (cg-RX-API-DMAC7.html)
CN (1) CN115003794A (cg-RX-API-DMAC7.html)
AU (1) AU2020337444A1 (cg-RX-API-DMAC7.html)
BR (1) BR112022003659A2 (cg-RX-API-DMAC7.html)
CA (1) CA3151636A1 (cg-RX-API-DMAC7.html)
IL (1) IL290891A (cg-RX-API-DMAC7.html)
MX (1) MX2022002418A (cg-RX-API-DMAC7.html)
PH (1) PH12022550392A1 (cg-RX-API-DMAC7.html)
TW (1) TW202122573A (cg-RX-API-DMAC7.html)
WO (1) WO2021041591A1 (cg-RX-API-DMAC7.html)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
CN114231481A (zh) * 2021-12-21 2022-03-25 中国人民解放军总医院 一种重编程真皮成纤维细胞为内皮祖细胞的化学诱导方法

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KR102411018B1 (ko) 2015-08-18 2022-06-20 아스텔라스 인스티튜트 포 리제너러티브 메디슨 임상 제제
EP4372079A4 (en) * 2021-07-15 2025-07-30 Astellas Pharma Inc PERICYTE-LIKE CELLS EXPRESSING VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) AT A HIGH LEVEL
JP2025523987A (ja) * 2022-07-19 2025-07-25 ルング・バイオテクノロジー・パブリック・ベネフィット・コーポレイション 内皮細胞を分化させる方法
CN118177150B (zh) * 2024-04-15 2024-12-03 中国医学科学院医学实验动物研究所 遗传多样性高血压小鼠模型的建立与基因转录调控分析

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AU2007238660C1 (en) 2006-04-14 2013-11-07 Astellas Institute For Regenerative Medicine Hemangio-colony forming cells
BRPI0912201A2 (pt) 2008-05-06 2019-09-24 Advanced Cell Tech Inc células formadoras de colônias de hemangios e células de hemangio não enxertantes
WO2010001375A1 (en) * 2008-06-30 2010-01-07 University College Cork, National University Of Ireland, Cork Primitive vascular progenitor cells and uses thereof
US20110305672A1 (en) * 2008-07-25 2011-12-15 University Of Georgia Research Foundation, Inc. COMPOSITIONS FOR MESODERM DERIVED ISL1+ MULTIPOTENT CELLS (IMPs), EPICARDIAL PROGENITOR CELLS (EPCs) AND MULTIPOTENT CD56C CELLS (C56Cs) AND METHODS OF PRODUCING AND USING SAME
US20140045265A1 (en) * 2011-02-16 2014-02-13 Salk Institute For Biological Studies Robust and efficient differentiation of human pluripotent stem cells to multipotent vascular progenitors
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PL2785359T3 (pl) 2011-11-30 2018-12-31 Astellas Institute For Regenerative Medicine Mezenchymalne komórki zrębowe i związane z nimi zastosowania
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KR102411018B1 (ko) 2015-08-18 2022-06-20 아스텔라스 인스티튜트 포 리제너러티브 메디슨 임상 제제
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114231481A (zh) * 2021-12-21 2022-03-25 中国人民解放军总医院 一种重编程真皮成纤维细胞为内皮祖细胞的化学诱导方法

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CN115003794A (zh) 2022-09-02
IL290891A (en) 2022-04-01
JP7894203B2 (ja) 2026-07-23
US20220288131A1 (en) 2022-09-15
WO2021041591A1 (en) 2021-03-04
MX2022002418A (es) 2022-03-22
PH12022550392A1 (en) 2022-12-19
BR112022003659A2 (pt) 2022-05-24
JP2026001090A (ja) 2026-01-06
AU2020337444A1 (en) 2022-03-24
KR20220049618A (ko) 2022-04-21
CA3151636A1 (en) 2021-03-04
EP4022038A1 (en) 2022-07-06
JP2022545737A (ja) 2022-10-28

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