TW202112377A - 藉由jak抑制劑局部治療白斑症 - Google Patents
藉由jak抑制劑局部治療白斑症 Download PDFInfo
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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| BR112020008850A2 (pt) | 2017-11-03 | 2020-10-20 | Aclaris Therapeutics, Inc. | composto, composição farmacêutica e método para tratar uma doença mediada por jak1 e jak3 |
| JP7591500B2 (ja) | 2018-08-10 | 2024-11-28 | アクラリス セラピューティクス，インコーポレイテッド | ピロロピリミジンｉｔｋ阻害剤 |
| US11602536B2 (en) * | 2019-06-10 | 2023-03-14 | Incyte Corporation | Topical treatment of vitiligo by a JAK inhibitor |
| US20230364095A1 (en) * | 2020-09-16 | 2023-11-16 | Incyte Corporation | Topical treatment of vitiligo |
| CN117279915A (zh) * | 2021-02-18 | 2023-12-22 | 阿克拉瑞斯治疗股份有限公司 | Jak1/3抑制剂的局部制剂及其用于特异性皮炎和其他皮肤病况的治疗的方法 |
| JP2024509383A (ja) * | 2021-02-18 | 2024-03-01 | アクラリス セラピューティクス，インコーポレイテッド | アトピー性皮膚炎及びその他の皮膚状態の治療のためのｊａｋ１／３阻害剤の局所製剤及びその使用方法 |
| EP4389114A4 (en) * | 2021-08-19 | 2025-09-03 | Zhuhai United Laboratories Co Ltd | LOCAL TOPICAL FORMULATION CONTAINING A JAK INHIBITOR OR A SALT THEREOF OR A CRYSTALLINE FORM THEREOF, PREPARATION METHOD THEREOF AND CORRESPONDING APPLICATION |
| CN115869321A (zh) | 2021-09-28 | 2023-03-31 | 杭州中美华东制药有限公司 | 一种芦可替尼组合物及其制备方法 |
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| PT1441737E (pt) | 2001-10-30 | 2006-12-29 | Dana Farber Cancer Inst Inc | Derivados de estrutura como inibidores da actividade do receptor de tirosina cinase flt3 |
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| AR042052A1 (es) | 2002-11-15 | 2005-06-08 | Vertex Pharma | Diaminotriazoles utiles como inhibidores de proteinquinasas |
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| EP2740731B1 (en) | 2007-06-13 | 2016-03-23 | Incyte Holdings Corporation | Crystalline salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile |
| EA202091303A3 (ru) | 2010-05-21 | 2021-05-31 | Инсайт Холдингс Корпорейшн | Композиция ингибитора jak для местного применения |
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| US11957931B2 (en) | 2017-04-26 | 2024-04-16 | Yale University | Compositions and methods for treating vitiligo |
| US20190060311A1 (en) | 2017-08-24 | 2019-02-28 | Aclaris Therapeutics, Inc. | Compositions and methods for treatment of vitiligo |
| WO2019191679A1 (en) | 2018-03-30 | 2019-10-03 | Incyte Corporation | Biomarkers for inflammatory skin disease |
| CN111374639A (zh) | 2018-12-28 | 2020-07-07 | 陈柏龄 | 败血症的菌种预测系统与方法 |
| US20210030672A1 (en) | 2019-06-10 | 2021-02-04 | Incyte Corporation | Topical treatment of vitiligo by a jak inhibitor |
| US11602536B2 (en) * | 2019-06-10 | 2023-03-14 | Incyte Corporation | Topical treatment of vitiligo by a JAK inhibitor |
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| IL290637A (en) | 2022-04-01 |
| EP3982971A1 (en) | 2022-04-20 |
| MA56215A (fr) | 2022-04-20 |
| JP7532511B2 (ja) | 2024-08-13 |
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| US11602536B2 (en) | 2023-03-14 |
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