TW202042824A - Tn-MUC1嵌合抗原受體（CAR）T細胞療法 - Google Patents

Tn-MUC1嵌合抗原受體（CAR）T細胞療法 Download PDF

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TW202042824A
TW202042824A TW109110245A TW109110245A TW202042824A TW 202042824 A TW202042824 A TW 202042824A TW 109110245 A TW109110245 A TW 109110245A TW 109110245 A TW109110245 A TW 109110245A TW 202042824 A TW202042824 A TW 202042824A
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muc1
cells
acid sequence
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TW109110245A
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艾弗里 波西
卡爾 Ｈ 俊恩
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賓夕法尼亞大學董事會
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TW109110245A 2019-03-27 2020-03-26 Tn-MUC1嵌合抗原受體（CAR）T細胞療法 TW202042824A (zh)

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US201962824532P 2019-03-27 2019-03-27
US62/824,532 2019-03-27
US201962881269P 2019-07-31 2019-07-31
US62/881,269 2019-07-31

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US (2) US11090336B2 (https=)
EP (1) EP3947471A4 (https=)
JP (2) JP7654557B2 (https=)
CN (2) CN120944827A (https=)
TW (1) TW202042824A (https=)
WO (1) WO2020198413A1 (https=)

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JP2024508894A (ja) * 2021-03-03 2024-02-28 ドラゴンフライ セラピューティクス， インコーポレイテッド Ｎｋｇ２ｄ、ｃｄ１６、及び腫瘍関連抗原に結合する多特異性結合タンパク質を使用して癌を治療する方法
KR20240007179A (ko) * 2021-04-30 2024-01-16 셀렉티스 에스.에이. 고형 종양 암 면역 요법을 위한 새로운 항-muc1 car 및 유전자 편집된 면역세포
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CN113943718B (zh) * 2021-10-11 2023-10-24 北京大学 一种糖基转移酶及其在Tn抗原的标记、成像和检测中的应用
EP4543467A2 (en) * 2022-06-24 2025-04-30 Orgenesis, Inc Chimeric antigen receptor with modified hinge and transmembrane domain and uses thereof
CN116284409A (zh) * 2022-07-08 2023-06-23 上海优替济生生物医药有限公司 Gpc3 car-t细胞及其在制备治疗癌症的药物中的用途
WO2024091848A2 (en) * 2022-10-25 2024-05-02 The Trustees Of The University Of Pennsylvania Anti-ceacam6 car-t cells for the treatment of ceacam6+ tumors
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