TW202039508A - 作為sting促效劑之三環化合物及其製備方法及醫藥用途 - Google Patents
作為sting促效劑之三環化合物及其製備方法及醫藥用途 Download PDFInfo
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- TW202039508A TW202039508A TW108146054A TW108146054A TW202039508A TW 202039508 A TW202039508 A TW 202039508A TW 108146054 A TW108146054 A TW 108146054A TW 108146054 A TW108146054 A TW 108146054A TW 202039508 A TW202039508 A TW 202039508A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/06—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
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|---|---|---|---|
| US201862779907P | 2018-12-14 | 2018-12-14 | |
| US62/779,907 | 2018-12-14 |
Publications (1)
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|---|---|
| TW202039508A true TW202039508A (zh) | 2020-11-01 |
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|---|---|---|---|
| TW108146054A TW202039508A (zh) | 2018-12-14 | 2019-12-16 | 作為sting促效劑之三環化合物及其製備方法及醫藥用途 |
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| Country | Link |
|---|---|
| US (1) | US20220056044A1 (https=) |
| EP (1) | EP3873896A4 (https=) |
| JP (1) | JP2022511540A (https=) |
| CN (1) | CN113195473B (https=) |
| TW (1) | TW202039508A (https=) |
| WO (1) | WO2020124059A1 (https=) |
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| WO2021206158A1 (ja) | 2020-04-10 | 2021-10-14 | 小野薬品工業株式会社 | がん治療方法 |
| CN119110800A (zh) * | 2022-02-21 | 2024-12-10 | 健道生物医药有限公司 | 干扰素基因刺激因子(sting)调节剂及其组合物和方法 |
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| FR2747678B1 (fr) * | 1996-04-22 | 1998-05-22 | Synthelabo | Composes derives d'imidazobenzoxazine, leurs procedes de preparation et leurs utilisations en therapeutique |
| ECSP003637A (es) * | 1999-08-31 | 2002-03-25 | Agouron Pharma | Inhibidores triciclicos de poli (adp-ribosa) polimerasas |
| KR20080035576A (ko) * | 2005-08-05 | 2008-04-23 | 아스트라제네카 아베 | 트리사이클릭 벤즈이미다졸 및 대사체 글루타메이트 수용체조절제로서 이들의 용도 |
| GB201220157D0 (en) * | 2012-11-08 | 2012-12-26 | Selvita Sa | Substitute tricyclic benzimidazoles as kinase inhibitors |
| MX366703B (es) * | 2013-03-15 | 2019-07-22 | Incyte Holdings Corp | Heterociclos tricíclicos como inhibidores de la proteína bet. |
| HRP20220936T1 (hr) * | 2016-04-07 | 2022-10-28 | Glaxosmithkline Intellectual Property Development Limited | Heterociklički amidi korisni kao modulatori proteina |
| JP2021530442A (ja) * | 2018-06-28 | 2021-11-11 | ジエンス ヘンルイ メデイシンカンパニー リミテッドJiangsu Hengrui Medicine Co., Ltd. | 縮合三環系複素環化合物およびその治療上の使用 |
| CN111655682B (zh) * | 2018-08-29 | 2024-05-31 | 杭州阿诺生物医药科技有限公司 | 一种高活性sting蛋白激动剂化合物 |
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- 2019-12-14 US US17/413,287 patent/US20220056044A1/en not_active Abandoned
- 2019-12-14 CN CN201980081825.1A patent/CN113195473B/zh active Active
- 2019-12-14 JP JP2021532155A patent/JP2022511540A/ja active Pending
- 2019-12-16 TW TW108146054A patent/TW202039508A/zh unknown
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| CN113195473A (zh) | 2021-07-30 |
| EP3873896A4 (en) | 2022-08-31 |
| WO2020124059A1 (en) | 2020-06-18 |
| JP2022511540A (ja) | 2022-01-31 |
| EP3873896A1 (en) | 2021-09-08 |
| CN113195473B (zh) | 2022-11-22 |
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