TW202031265A - 用於皮下投藥之醫藥調配物 - Google Patents

用於皮下投藥之醫藥調配物 Download PDF

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Publication number
TW202031265A
TW202031265A TW108141664A TW108141664A TW202031265A TW 202031265 A TW202031265 A TW 202031265A TW 108141664 A TW108141664 A TW 108141664A TW 108141664 A TW108141664 A TW 108141664A TW 202031265 A TW202031265 A TW 202031265A
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TW
Taiwan
Prior art keywords
pharmaceutical composition
levodopa
compound
stable liquid
liquid aqueous
Prior art date
Application number
TW108141664A
Other languages
English (en)
Chinese (zh)
Inventor
伊哈布 默沙
馬修 羅斯布勞
費茲 傑米爾
南西 西凡
莫里奇歐 Ｆ 費雪爾里斯
韋寜 Ｚ 羅比森
查爾斯 Ｓ 洛克
席維 史都特曼
Original Assignee
美商艾伯維有限公司
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Application filed by 美商艾伯維有限公司 filed Critical 美商艾伯維有限公司
Publication of TW202031265A publication Critical patent/TW202031265A/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW108141664A 2018-11-15 2019-11-15 用於皮下投藥之醫藥調配物 TW202031265A (zh)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US201862767546P 2018-11-15 2018-11-15
US62/767,546 2018-11-15
US201962843945P 2019-05-06 2019-05-06
US62/843,945 2019-05-06
US201962863101P 2019-06-18 2019-06-18
US201962863113P 2019-06-18 2019-06-18
US201962863093P 2019-06-18 2019-06-18
US62/863,113 2019-06-18
US62/863,093 2019-06-18
US62/863,101 2019-06-18
US201962898214P 2019-09-10 2019-09-10
US62/898,214 2019-09-10

Publications (1)

Publication Number Publication Date
TW202031265A true TW202031265A (zh) 2020-09-01

Family

ID=68835352

Family Applications (1)

Application Number Title Priority Date Filing Date
TW108141664A TW202031265A (zh) 2018-11-15 2019-11-15 用於皮下投藥之醫藥調配物

Country Status (14)

Country Link
US (3) US12251365B2 (enExample)
EP (1) EP3880210A1 (enExample)
JP (2) JP2022507528A (enExample)
KR (1) KR20210091139A (enExample)
CN (1) CN113015531A (enExample)
AU (2) AU2019379806B2 (enExample)
BR (1) BR112021009353A2 (enExample)
CA (1) CA3117983A1 (enExample)
IL (1) IL282842A (enExample)
MX (1) MX2021005776A (enExample)
SG (1) SG11202104499RA (enExample)
TW (1) TW202031265A (enExample)
UY (1) UY38473A (enExample)
WO (1) WO2020102628A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY38473A (es) 2018-11-15 2020-06-30 Abbvie Inc Formulaciones farmacéuticas para una administración subcutánea
AU2022352845A1 (en) * 2021-10-27 2024-04-11 Abbvie Inc. Subcutaneously administered foslevodopa/foscarbidopa treatments for advanced parkinson's disease

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Also Published As

Publication number Publication date
BR112021009353A2 (pt) 2021-11-23
EP3880210A1 (en) 2021-09-22
AU2019379806B2 (en) 2025-08-14
US20250186382A1 (en) 2025-06-12
AU2019379806A1 (en) 2021-05-27
MX2021005776A (es) 2021-07-02
AU2025256148A1 (en) 2025-11-13
US12251365B2 (en) 2025-03-18
US20200155578A1 (en) 2020-05-21
US20250325507A1 (en) 2025-10-23
KR20210091139A (ko) 2021-07-21
CA3117983A1 (en) 2020-05-22
SG11202104499RA (en) 2021-05-28
WO2020102628A1 (en) 2020-05-22
IL282842A (en) 2021-06-30
CN113015531A (zh) 2021-06-22
UY38473A (es) 2020-06-30
JP2022507528A (ja) 2022-01-18
JP2024174894A (ja) 2024-12-17

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