TW201929886A - 淨膚補充劑 - Google Patents
淨膚補充劑 Download PDFInfo
- Publication number
- TW201929886A TW201929886A TW107145988A TW107145988A TW201929886A TW 201929886 A TW201929886 A TW 201929886A TW 107145988 A TW107145988 A TW 107145988A TW 107145988 A TW107145988 A TW 107145988A TW 201929886 A TW201929886 A TW 201929886A
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- Taiwan
- Prior art keywords
- around
- medicine composition
- chinese medicine
- traditional chinese
- peony
- Prior art date
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Abstract
揭露一種淨膚補充劑/用於痤瘡之藥物組成物,包括:一口服給藥劑量包括介於約3000 至 9000 mg之間的該中藥組成物,該中藥組成物包括以比例計:桃、紅花、白芷、皂荚、光瓣菫菜、牡丹和梔子花
的每一者約3.8至7.6%;二葉葎和黃芩
的每一者約5.7至7.6%;丹參
約3.8至5.7%;黃檗
約2.5至5.7%;龍膽
約2.5至7.6%;以及蒲公英
和金銀花 / 黃連 / 苦參
中任一者的每一者約0至7.6%。
Description
相關申請
本發明請求來自於2017年12月20日提交的澳洲臨時專利申請第 2017905083號的優先權,其完整內容藉由引用併入此處。
本發明整體關於一種膳食補充劑,以及一種用於製備這種口服治療施用的過程,膳食補充劑用於增強與像是痤瘡和皮膚炎症的皮膚症狀相關的皮膚健康,其使用天然存在的成分作為一種口服治療過程的部分。
在西方文明中,症狀的治療,像是痤瘡以及其他皮膚相關的症狀,大多已經聚焦於專注在除去阻塞毛孔的清潔皮膚以及施用像是外用乳劑和凝膠的藥物治療。此種治療的失效經常導致結合此外用的治療及口服抗生素,口服抗生素作用為殺死造成在阻塞的毛孔周圍的炎症的細菌。
典型地,此種治療在治療輕微的皮膚炎症和與可能由於激素水準的變化和增加的油產生而經歷皮膚問題之青少年相關的症狀已經適度成功。然而,此等治療可能存在副作用,並且此種兩步驟治療對於所有患者可能並不成功。因此,對於那些患有更嚴重的痤瘡或皮膚炎症病例的人而言,找到一種成功的治療方法可能會有很多挫折感,該治療方法可以併入雷射或光治療以減少炎症並攻擊造成痤瘡的細菌。此種治療可能是耗時且昂貴的,然而有不同程度的成功。
在東方文明中,有透過天然存在產物和補品的使用來解決各種健康症狀的歷史方法。包含天然動物和植物的傳統中藥材長期以來已被使用於治療包括皮膚病的各種症狀,具有持續的成功。然而,傳統中藥原料為了使用被加工和製備的方式長期以來阻止西方文明對此種治療的接納。因此,需要提供一種具有簡單配方的傳統中藥組合物以及為了使用而用於製備該組合物的便利方法。
以上對於習知提議或產品的引用和描述並非旨在且不應被詮釋為本領域中具有通常知識者的陳述或引進。特別地,以下習知技術的討論非關於本領域技術人員通常或熟知的內容,而是有助於本發明具發明性步驟的理解,其中切合的習知技術提議的識別只是一部分。
根據第一方面,提供了一種治療皮膚炎症症狀的方法,包括:向患有皮膚炎症的患者口服給藥一每日劑量的傳統中藥組成物,其中所述每日劑量包括介於約3000至9000 mg之間的該中藥組成物,該中藥組成物包括以比例計:桃(Prunus persica
)、紅花(Carthamus tinctorius
)、白芷(Angelica dahurica
)、皂荚(Gleditsia sinensis
)、光瓣菫菜(Viola yedoensis
)、牡丹(Paeonia suffruticosa
)和梔子花(gardenia jasminoides
)的每一者約3.8至7.6%;二葉葎(Oldenlandia diffusa
)和黃芩(Scutellaria baicalensis
)的每一者約5.7至7.6%;丹參(Salvia miltiorrhiza
)約3.8至5.7%;黃檗(Phellodendron amurense
)約2.5至5.7%;龍膽(Gentiana scabra
)約2.5至7.6%;以及蒲公英(Taraxacum mongolicum
)和金銀花(Lonicera japonica
)的每一者約0至7.6%。
在該第一方面的具體實施例中,該中藥組成物還包括以比例計薑(Zingiber officinale
)和甘草(Glycyrrhiza uralensis
)的每一者介於0至3.8%;以及當歸(Angelica polymorpha
)0至5.7%。
根據另一方面,提供了一種中草藥組成物,包括以比例計:桃、紅花、白芷、皂荚、光瓣菫菜、牡丹和梔子花的每一者約3.8至7.6%;二葉葎和黃芩的每一者約5.7至7.6%;丹參的3.8至5.7%左右;黃檗約2.5至5.7%;龍膽約2.5至7.6%的;以及蒲公英和金銀花/黃連(Rhizoma Coptidis
)/苦參(Sophora Flavescens
)中的每一者約0至7.6%。
再根據另一個方面,提供了一種治療皮膚炎症症狀的方法,包括:向患有一皮膚炎症的一患者口服給藥每日劑量的傳統中藥組成物,其中所述每日劑量在約750 mg的該中藥組成物的錠劑中被給藥,該錠劑包括包括以重量計:桃、紅花、丹參、牡丹、龍膽和黃芩的每一者2至3%;二葉葎,草本(Herba
)、白芷、皂荚,棘(Spina
)、光瓣菫菜,草本、蒲公英,草本、金銀花的每一者4至5%;黃檗2.3至3.5%;以及梔子花1.5至2.5%。
在此方面的一個具體實施例中,該中藥組合物還可以包括以重量計薑、當歸以及甘草的每一者0至2%。
根據另一方面,揭露了一種中草藥組合物,大致包括以重量計:桃、紅花、丹參、牡丹、龍膽和黃芩的每一者2至3%;二葉葎,草本、白芷、皂荚、棘(Spina
)、光瓣菫菜,草本、蒲公英,草本、金銀花的每一者4至5%;黃檗2.3至3.5%;以及梔子花1.5至2.5%。
本發明將於以下參考較佳具體實施例更詳細地描述。
在較佳的形式中,本發明以錠劑或膠囊形式提供,由具有皮膚炎症症狀(像是痤瘡)的個體用於口服攝取。錠劑可以是未包衣的,然而在某些情況下,可以將包衣(像是腸包衣)施用於錠劑,以控制其中所含有的活性成分的傳遞和攝取。然而,在替代的具體實施例中,本發明可以將成分以粉末或原始形式來呈現,藉此它們可以以口服攝取或外部施用於經歷炎症的皮膚表面,以解決此種炎症。
本發明的主要成分在以下表1中列出,連同該成分從植物取出的部位。
上述成分的每一者具有根據中藥的各種性質,以對付各種與皮膚相關的症狀。例如,已知桃、紅花以及丹參已知用於增加血液循環和治療血液滯留。白花蛇舌草(Hedyotis diffusa)也已知為有用於減少熱和毒性水準並且打破血液滯留,如光瓣菫菜、蒲公英、金銀花、黃檗、牡丹以及和梔子(Gardenia Florida)。白芷和甘草也以其減少皮膚上的腫脹以及膿腫的用途而已知。
薑、當歸以及甘草的每一者為次要成分,並且因其與其他成分一起作用而提高其功效的能力而已知。
表1
關於金銀花,取決於可得性,此成分可以由更易可得的成分替代,像是黃連(Rhizoma Coptidis)或苦參(Sophora Flavescens)。
在此具體實施例中,馬鈴薯澱粉被使用作為賦形劑或載體,以將成分以錠劑形式黏合在一起。
表2描述了每750 mg錠劑的每種成分的比例。
表2
為了製備錠劑,上述原料的每一者被裝入萃取器中並且加入水,達組合的原料之重量的十倍。構成原混合物的材料的比例示於表3中。之後,在將該混合物帶往在100℃下沸騰之前,該混合物容許浸泡持續1小時。將該混合物在此溫度下保持持續約1小時,之後液體被萃取至專用的儲存罐中,並且根據上述體積,萃取器用水重新填充,並重複萃取過程。
表3
然後將被萃取的液體送入濃縮器中,其中液體被維持在40至60%持續2小時,直到水含量減低至約35至60%,並且液體呈糊狀稠度。然後將濃縮的糊狀物冷藏。
在此具體實施例中,載體馬鈴薯澱粉然後被加入製粒機中,並且被濃縮的糊狀物被噴入造粒機中,其中溫度設定在約55至65℃。為了品質控制目的,對於在此過程中生產的顆粒的分析可以進行,在其後顆粒與另外的賦形劑(像是硬脂酸鎂)混合,然後形成錠劑。然後將錠劑包裝在瓶中以便配送。
本發明成分的組成物是基於痤瘡主要由皮膚中的熱、血液滯留、毒性和炎症所造成的知識來確定。上述提及的主要成分已被選擇以解決這些問題中的每一者,以減少炎症並增加循環和血液流動並且維持避免毒素積聚的健康皮膚溫度。
本發明的錠劑只有在與中藥專家的初步諮詢後才可以推薦予患者。在某些例子中,可能需要增加成分的百分比以解決在諮詢過程中識別的特定問題。然而,也被展望錠劑可以在零售銷路及其類似者中提供,用於無需初步諮詢的購買。
透過本說明書和權利要求書,除非反對被明確陳述或上下文另有要求,否則用詞“包括”及其衍生詞旨在具有相容性而非排他性的意義。也就是說,用詞“包括”及其衍生詞將被用來指出不僅它直接引用的所列舉的組成、步驟或特徵的包含,除非反對被明確陳述或上下文另有要求,還包括未特定列舉的其他組成、步驟或特徵。
將被本領域技術人員理解,在不脫離本發明的精神和範圍的情況下,此處所描述的本發明的方法可以做成許多修飾和變化。
Claims (3)
- 一種治療皮膚炎症症狀的方法,包括:向患有一皮膚炎症的一患者口服給藥一每日劑量的一傳統中藥組成物,其中所述每日劑量包括介於約3000至9000 mg之間的該中藥組成物,該中藥組成物包括以比例計:桃、紅花、白芷、皂荚、光瓣菫菜、牡丹和梔子花的每一者約3.8至7.6%;二葉葎和黃芩的每一者約5.7至7.6%;丹參約3.8至5.7%;黃檗約2.5至5.7%;龍膽約2.5至7.6%;以及蒲公英和金銀花/黃連/苦參中任一者的每一者約0至7.6%。
- 如申請專利範圍第1項所述的方法,其中該中藥組成物還包括以比例計薑和甘草的每一者介於0至3.8%;以及當歸0至5.7%。
- 一種中草藥組成物,包括以比例計:桃、紅花、白芷、皂荚、光瓣菫菜、牡丹和梔子花的每一者約3.8至7.6%;二葉葎和黃芩的每一者約5.7至7.6%;丹參的3.8至5.7%左右;黃檗約2.5至5.7%;龍膽約2.5至7.6%的;以及蒲公英和金銀花/黃連/苦參中任一者的每一者約0至7.6%。
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CN101214321A (zh) * | 2007-01-01 | 2008-07-09 | 何顺洪 | 一种治疗痤疮的药物 |
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- 2018-12-20 WO PCT/AU2018/000266 patent/WO2019119018A1/en unknown
- 2018-12-20 EP EP18893043.2A patent/EP3727416A4/en active Pending
- 2018-12-20 JP JP2020543050A patent/JP2021516223A/ja active Pending
- 2018-12-20 CN CN201880087140.3A patent/CN111629741A/zh active Pending
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2024
- 2024-09-19 AU AU2024219900A patent/AU2024219900A1/en active Pending
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AU2018387473A1 (en) | 2020-07-09 |
EP3727416A4 (en) | 2021-09-01 |
WO2019119018A1 (en) | 2019-06-27 |
CN111629741A (zh) | 2020-09-04 |
KR20200108433A (ko) | 2020-09-18 |
US20200323941A1 (en) | 2020-10-15 |
US11311595B2 (en) | 2022-04-26 |
EP3727416A1 (en) | 2020-10-28 |
JP2021516223A (ja) | 2021-07-01 |
AU2024219900A1 (en) | 2024-10-10 |
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