CN107412684A - 一种石蛙蝌蚪炎症用药及其制备工艺 - Google Patents

一种石蛙蝌蚪炎症用药及其制备工艺 Download PDF

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CN107412684A
CN107412684A CN201710800659.9A CN201710800659A CN107412684A CN 107412684 A CN107412684 A CN 107412684A CN 201710800659 A CN201710800659 A CN 201710800659A CN 107412684 A CN107412684 A CN 107412684A
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frog tadpole
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兰群珍
周秋白
钟杰
姜文灏
吴早保
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Guixi Fuqun Stone Frog Culture Professional Cooperatives
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Abstract

一种石蛙蝌蚪炎症用药及其制备工艺，其组成原料的重量配比为：黄芪9%~11%，板蓝根2%~4%，知母2%~4%，淫羊藿3.5%~4.5%，茵陈1%~3%，大黄1%~4%，郁金0.5~1.5%，连翘1%~3%，柴胡1%~3%，阿莫西林17%~23%，电解多维8%~12%，恩诺沙星16%~25%，硫酸新霉素粉8%~12%，姜黄8%~12%。本发明的石蛙蝌蚪炎症用药，提高石蛙蝌蚪胃肠道功能免疫力，促使益生菌大量繁殖并抑制有害菌，可以在石蛙蝌蚪的生长过程中最大限度地调节恢复胃肠道的健康代谢，从根本上解决石蛙蝌蚪的代谢问题。

Description

一种石蛙蝌蚪炎症用药及其制备工艺
技术领域
本发明属于水产业用药配比加工技术领域，具体涉及一种石蛙蝌蚪炎症用药及其制备工艺。
背景技术
蛙类，以其独有的药用价值与营养价值而日益被人们所重视。蛙类养殖，是目前全国推广的水产养殖行业。而石蛙是我国蛙类养殖业的后起之秀，是农民增收的新热点，发展较快，前景看好。
然而蛙类养殖是一个风险大、投资高的产业，由于现有养殖过程中存在养殖场地、水质、饲料、气候的诸多影响，导致石蛙的抗病能力下降，且生长缓慢、肉质量差。尤其是蝌蚪期疫力不强，体内能量代谢的调节功能不全，容易发生呼吸道和肠道病变，从而导致蝌蚪存活率极低。
现有的养殖技术大部分只能针对于蛙类的生长期和成年期，对于还未变态的蝌蚪没有具体的治疗药物。因此如何配置针对于蝌蚪呼吸道和肠道病变的问题，成为了当今蛙类养殖的一项难题。
发明内容
本发明提出了一种石蛙蝌蚪炎症用药及其制备工艺，该药提高了石蛙蝌蚪呼吸道和胃肠道功能免疫力，促使益生菌大量繁殖并抑制有害菌，加快了石蛙蝌蚪的健康代谢，使得石蛙蝌蚪提高成活率，加快生长速度。
本发明的技术方案是这样实现的：
一种石蛙蝌蚪炎症用药，包括以下各重量比组分：黄芪9%~11%，板蓝根2%~4%，知母2%~4%，淫羊藿3.5%~4.5%，茵陈1%~3%，大黄1%~4%，郁金0.5~1.5%，连翘1%~3%，柴胡1%~3%， 阿莫西林17%~23%，电解多维8%~12%，恩诺沙星16%~25%，硫酸新霉素粉8%~12%，姜黄8%~12%。
在本发明的石蛙蝌蚪炎症用药中，其优选为由以下原料按照如下的重量配比制成：黄芪10%，板蓝根3%，知母3%，淫羊藿4%，茵陈2%，大黄2%，郁金1%，连翘3%，柴胡2%， 阿莫西林20%，电解多维10%，恩诺沙星20%，硫酸新霉素粉10%，姜黄10%。
本发明的石蛙蝌蚪炎症用药还包括：1%~3% 的夏枯草粉末、0.8%~1% 的五倍子粉末以及0.1%~0.2% 的葡萄糖酸镁。
一种石蛙蝌蚪炎症用药的制备工艺，其制作步骤如下：
A、将所述比例的板蓝根，郁金，连翘，柴胡，知母置入容器内加水盖住草药原料，浸泡30分钟后煎煮30-80分钟；去杂质，再将煎煮好的药水导入蒸发釜中进行蒸发处理，制得物碾磨成粉备用；
B、将所述比例黄芪，茵陈，淫羊藿，大黄，姜黄碾磨成粉末再置入容器内加水煎煮60分钟，去杂质，再将药水导入蒸发釜中进行蒸发处理，制得颗粒备用；
C、将上述A、B制得颗粒按所述比例阿莫西林，电解多维，硫酸新霉素粉混合；加入恩诺沙星混合即得。
在本发明的炎症用药的制备工艺中，最后在投料中加入夏枯草粉末、五倍子粉末、葡萄糖酸镁搅拌制备。
在本发明中所述的黄芪：其有增强机体免疫功能、保肝、利尿、抗衰老、抗应激、降压和较广泛的抗菌作用。
板蓝根：苦，寒。具有清热解毒，凉血利咽之功效。常用于温疫时毒，发热咽痛，温毒发斑，痄腮，烂喉丹痧，大头瘟疫，丹毒，痈肿。
知母：是多年生草本植物，根状茎，叶由基部丛生细长披针形，花茎自叶丛中长出，圆柱形直立，总状花絮，成簇，生在顶部成穗状；花粉红色，淡紫色至白色；果实长椭圆形，具有清热泻火，滋阴润燥的特定功效。
淫羊藿：味辛甘性温，有治疗四肢麻木，半身不遂，神经衰弱，健忘，耳鸣，目眩等的功效。
茵陈：茵陈清热利湿；退黄。主治：黄疸、小便不利、湿疮瘙痒、传染性黄疸型肝炎等。药理学研究有利胆，保护肝功能，解热，抗炎，降血脂，降压，扩冠等作用。
大黄：具有攻积滞、清湿热、泻火、凉血、祛瘀、解毒等功效。
郁金：活血止痛，行气解郁，清心凉血，利胆退黄。常用于胸胁刺痛，胸痹心痛，经闭痛经，乳房胀痛，热病神昏，癫痫发狂，血热吐衄，黄疸尿赤。
连翘：清热，解毒，散结，消肿。对于温热，丹毒，斑疹，痈疡肿毒，瘰疬，小便淋闭有很好的治疗效果。
柴胡：有和解表里，疏肝升阳之功效。常用于感冒发热、寒热往来、疟疾、肝郁气滞、胸肋胀痛等病症。
阿莫西林：是一种最常用的半合成青霉素类广谱β-内酰胺类抗生素，为一种白色粉末，半衰期约为61.3分钟。在酸性条件下稳定，胃肠道吸收率达90%。
阿莫西林杀菌作用强，穿透细胞膜的能力也强。是目前应用较为广泛的口服半合成青霉素之一，其制剂有胶囊、片剂、颗粒剂、分散片等等，现在常与克拉维酸合用制成分散片。
电解多维：其主要成分为维生素A、维生素D3、维生素E、维生素K、维生素B2、维生素B1、叶酸、右旋泛酸、钾元、钠元素维生素B12；是一种非常有效的营养性添加剂。
恩诺沙星：是一种微黄色或淡黄色结晶性粉末，味苦，不溶于水，是目前被国家指定为动物专用药。对大肠杆菌、克雷白杆菌、沙门氏菌、变形杆菌、绿脓杆菌、嗜血杆菌、多杀性巴氏杆菌、溶血性巴氏杆菌、金葡菌、链球菌等都有杀菌效用。
硫酸新霉素粉：主要成分是头孢曲松钠、硫酸新霉素、黄连素、甲硝唑、粘膜修复因子。目前主要治疗鸡的肠毒综合症、坏死性肠炎、溃疡性肠炎。
姜黄：常用于治心腹痞满胀痛，臂痛，症瘕，妇女血瘀经闭，产后瘀停腹痛，跌扑损伤，痈肿。
实施本发明的这种石蛙蝌蚪炎症用药，具有以下有益效果：该炎症用药可以提高石蛙蝌蚪胃肠道功能免疫力，促使益生菌大量繁殖并抑制有害菌，可以在石蛙蝌蚪的生长过程中最大限度地调节恢复胃肠道的健康代谢，从根本上解决石蛙蝌蚪的代谢问题。该炎症用药还对石蛙蝌蚪具有强烈的诱食作用，从而提高石蛙蝌蚪采食量，加快其生长速度，同时保持石蛙的营养价值，食用安全，生存适应性强。夏枯草粉末可以消肿明目、五倍子粉末具有消炎止血的功效与葡萄糖酸镁搭配具有增加药物营养的作用，达到治疗与养护的功效。
具体实施方式
下面结合具体实施方式对本专利的技术方案作进一步详细地说明。
实施例1
一种石蛙蝌蚪炎症用药，该药物组分重量配比为：黄芪9份，板蓝根2份，知母2份，淫羊藿3.5份，茵陈1份，大黄1份，郁金0.5份，连翘1份，柴胡1份， 阿莫西林17份，电解多维8份，恩诺沙星16份，硫酸新霉素粉8份，姜黄8份。
其中处理工艺步骤为：
1、板蓝根，郁金，连翘，柴胡，知母置入容器内，加水盖住草药原料，浸泡30分钟。然后煎煮30分钟；去杂质，再将煎煮好的药水导入蒸发釜中进行蒸发处理，制制得物碾磨成粉备用；。
2、将黄芪，茵陈，淫羊藿，大黄，姜黄碾磨成粉末再置入容器内加水煎煮60分钟，去杂质，再将药水导入蒸发釜中进行蒸发处理，制得颗粒备用。
3、将上述1、2制得颗粒按所述比例阿莫西林，电解多维，硫酸新霉素粉混合；加入恩诺沙星混合即得。
还可以在投料中加入夏枯草粉末1份、五倍子粉末0.8份、葡萄糖酸镁0.1份搅拌制备。以便更好地增加其药效。
实施例2
一种石蛙蝌蚪炎症用药，该药物组分重量配比为：黄芪11份，板蓝根4份，知母4份，淫羊藿4.5份，茵陈3份，大黄4份，郁金1.5份，连翘3份，柴胡3份， 阿莫西林23份，电解多维12份，恩诺沙星25份，硫酸新霉素粉12份，姜黄12份。
其中处理工艺步骤为：
1、板蓝根，郁金，连翘，柴胡，知母置入容器内，加水盖住草药原料，浸泡30分钟。然后煎煮80分钟；去杂质，再将煎煮好的药水导入蒸发釜中进行蒸发处理，制得物碾磨成粉备用。
2、将黄芪，茵陈，淫羊藿，大黄，姜黄碾磨成粉末再置入容器内加水煎煮60分钟，去杂质，再将药水导入蒸发釜中进行蒸发处理，制得颗粒备用。
3、将上述1、2制得颗粒按所述比例阿莫西林，电解多维，硫酸新霉素粉混合；加入恩诺沙星混合即得。
还可以在投料中加入夏枯草粉末3份、五倍子粉末1份、葡萄糖酸镁0.2份搅拌制备。以便更好地增加其药效。
实施例3
一种石蛙蝌蚪炎症用药，该药物组分重量配比为：黄芪10份，板蓝根3份，知母3份，淫羊藿4份，茵陈2份，大黄2份，郁金1份，连翘3份，柴胡2份， 阿莫西林20份，电解多维10份，恩诺沙星20份，硫酸新霉素粉10份，姜黄10份。
其中处理工艺步骤为：
1、板蓝根，郁金，连翘，柴胡，知母置入容器内，加水盖住草药原料，浸泡30分钟。然后煎煮60分钟；去杂质，再将煎煮好的药水导入蒸发釜中进行蒸发处理，制得物碾磨成粉备用；。
2、将黄芪，茵陈，淫羊藿，大黄，姜黄碾磨成粉末再置入容器内加水煎煮60分钟，去杂质，再将药水导入蒸发釜中进行蒸发处理，制得颗粒备用。
3、将上述1、2制得颗粒按所述比例阿莫西林，电解多维，硫酸新霉素粉混合；加入恩诺沙星混合即得。
还可以在投料中加入夏枯草粉末2份、五倍子粉末0.9份、葡萄糖酸镁0.15份搅拌制备。以便更好地增加其药效。
实施例4
选择150 尾患有呼吸道炎症的蝌蚪苗，随机分配成3组，一个对照组，两个实验组，每组50尾，对照组按照常规方法饲养。实验组1采用普通石蛙药物治疗，实验组2采用本发明的石蛙蝌蚪炎症用药治疗，观察周期为30 天。
实验表明，实验组2的平均成活率高于对照组和实验组1，实验组2后期的呼吸道感染和肠胃疾病发生率也较小。至此，本发明目的得以完成。
对于本领域技术人员而言，显然本发明不限于上述示范性实施例的细节，而且在不背离本发明的精神或基本特征的情况下，能够以其他的具体形式实现本发明。因此，无论从哪一点来看，均应将实施例看作是示范性的，而且是非限制性的，本发明的范围由所附权利要求而不是上述说明限定，因此旨在将落在权利要求的等同要件的含义和范围内的所有变化囊括在本发明内。
此外，应当理解，虽然本说明书按照实施方式加以描述，但并非每个实施方式仅包含一个独立的技术方案，说明书的这种叙述方式仅仅是为清楚起见，本领域技术人员应当将说明书作为一个整体，各实施例中的技术方案也可以经适当组合，形成本领域技术人员可以理解的其他实施方式。

Claims (5)

1.一种石蛙蝌蚪炎症用药，其特征在于，包括以下各重量比组分：黄芪9%~11%，板蓝根2%~4%，知母2%~4%，淫羊藿3.5%~4.5%，茵陈1%~3%，大黄1%~4%，郁金0.5~1.5%，连翘1%~3%，柴胡1%~3%， 阿莫西林17%~23%，电解多维8%~12%，恩诺沙星16%~25%，硫酸新霉素粉8%~12%，姜黄8%~12%。
2.根据权利要求1中所述的石蛙蝌蚪炎症用药，其特征在于，各组分的重量比为：黄芪10%，板蓝根3%，知母3%，淫羊藿4%，茵陈2%，大黄2%，郁金1%，连翘3%，柴胡2%，阿莫西林20%，电解多维10%，恩诺沙星20%，硫酸新霉素粉10%，姜黄10%。
3.根据权利要求1中所述的石蛙蝌蚪炎症用药，其特征在于：还包括夏枯草粉末1%~3%、五倍子粉末0.8%~1%以及葡萄糖酸镁0.1%~0.2%。
4.一种制备权利要求1所述的石蛙蝌蚪炎症用药的制备工艺，其制作步骤如下：
A、将所述比例的板蓝根，郁金，连翘，柴胡，知母置入容器内加水盖住草药原料，浸泡30分钟后煎煮30-80分钟；去杂质，再将煎煮好的药水导入蒸发釜中进行蒸发处理，制得物碾磨成粉备用；
B、将所述比例黄芪，茵陈，淫羊藿，大黄，姜黄碾磨成粉末再置入容器内加水煎煮60分钟，去杂质，再将药水导入蒸发釜中进行蒸发处理，制得颗粒备用；
C、将上述A、B制得颗粒按所述比例阿莫西林，电解多维，硫酸新霉素粉混合；加入恩诺沙星混合即得。
5.根据权利要求4中所述的石蛙蝌蚪炎症用药的制备工艺，其特征在于：最后在投料中加入夏枯草粉末、五倍子粉末、葡萄糖酸镁搅拌制备。
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114246929A (zh) * 2021-12-27 2022-03-29 江西阳际峰生态农业有限公司 一种石蛙蝌蚪消炎药及其生产方法
CN114246901A (zh) * 2021-12-29 2022-03-29 江西阳际峰生态农业有限公司 一种石蛙皮肤病药物及其生产方法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114246929A (zh) * 2021-12-27 2022-03-29 江西阳际峰生态农业有限公司 一种石蛙蝌蚪消炎药及其生产方法
CN114246901A (zh) * 2021-12-29 2022-03-29 江西阳际峰生态农业有限公司 一种石蛙皮肤病药物及其生产方法

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