TW201904558A - Cosmetic composition containing a mixture of arginine, hyaluronic acid and macadamia nut oil for improving hair moisturizing power - Google Patents

Abstract

The present invention relates to a cosmetic composition for improving the moisture of hair, containing a mixture of arginine, hyaluronic acid and macadamia nut oil and, more specifically, to a cosmetic composition for improving the moisture of hair, containing, as an active ingredient, a mixture of arginine, hyaluronic acid and macadamia nut oil, which increase the internal water content of hair (especially damaged hair). A cosmetic composition, according to the present invention, for improving the moisture of hair, preferably damaged hair, containing, as an active ingredient, a mixture of arginine, hyaluronic acid and macadamia nut oil exhibits effects of improving the ability to maintain the internal water of hair and increasing the period of water retention of hair by increasing the internal water content of hair and inhibiting the evaporation of the internal water of hair.

Description

Cosmetic composition containing arginine, hyaluronic acid and macadamia oil for improving hair moisturizing power

The present invention relates to a cosmetic composition containing a mixture of arginine, hyaluronic acid, and macadamia oil for improving the moisturizing power of hair, and in particular, to an active ingredient for improving the moisturizing power of hair, which can increase hair (particularly, Damaged hair) cosmetic composition with a mixture of arginine, hyaluronic acid and macadamia oil.

Hair is not directly related to life, but it has the functions of body protection, thermal insulation, and tactile sensation, and it resists friction from the outside, acts as a buffer, and protects the head from direct light and cold and summer heat.

In particular, the eyebrows, eyelashes, nose hairs, and ear hairs in hair have the function of preventing the invasion of sweat, dust, and insects, and have the function of absorbing unnecessary metals such as mercury, arsenic, and lead that are excreted from the body.

In addition, hair plays an important role in showing the characteristics of men and women on the modified surface. The same person can also make a different impression by changing the hairstyle and hair color. As above, hair not only protects the head, but also plays a role in grooming.

Hair is an elongated protein structure with an average thickness of about 0.07 mm. It is roughly divided into Hair Shaft protruding from the skin to the outside and Hair Root located inside the skin. The scalp has a basic structure and physiological functions similar to the skin. The hair follicles of the scalp (Hair Follicle) are more complicated and have more sebaceous glands than other parts. The root of the hair is a part located in the hair follicle, a part buried in the scalp, and the depth is about 2 to 4 mm. The bottom part of the hair root swells like a pearl. This part is called Hair Bulb, and the thickness of the hair is determined according to the size of this part.

When magnifying the cross section of the hair, three types of medulla (medulla) at the innermost part and the center, cortex (circle) surrounding the medulla, and cuticle (cuticle) at the outermost part were observed. section. The hair epidermis covers the surface of the hair. It is a chemically resistant part that surrounds the inside of the hair. From the outside, three layers called the upper epidermal layer (Epicuticle), outer epidermal layer (Exocuticle), and inner epidermal layer (Endocuticle) are formed. . The fur is located on the inner side of the hair epidermis and occupies most of the hair (85 ~ 90%). The main component is keratin, which is composed of cortical cells and intercellular binding substances. It is easily perm or stained due to its hydrophilic nature. The site of action. The medulla of the hair is located in the center of the hair and has a number of melanin particles. The medulla contains air due to many large and small vacuoles.

Hair is damaged by rubbing, heating, physical cutting, perming, decoloring, dyeing, sunlight, etc. First, the hair damage caused by heat is the heat generated in the dryer when drying after shampooing to evaporate moisture to dry, the hair will swell and cause deformation, and the black hair will change to tea brown. In addition, air bubbles begin to form in the pelt and medulla, the hair loses its elasticity, and the epidermis will melt.

Second, hair damage caused by perm is caused by bad treatment of perm fluid, insufficient time to leave, etc. When the hair is fragile, alkali remains in the hair, or oxidant remains, it can cause keratin degeneration and melanin discoloration.

Third, when alkaline agents and hydrogen peroxide are used as decoloring agents, the oxidative decolorization of melanin occurs due to hydrogen peroxide. When the depigmenting agent is repeatedly used for a short period of time, the hair will be repeatedly swollen and softened, or the hair epidermis will be staggered and bent, causing damage.

Finally, in the sun's rays, the hair's keratin is damaged by infrared and ultraviolet rays, causing protein denaturation.

As mentioned above, modern people damage their hair by perming, blowing hair, and dyeing hair. It is difficult to avoid frequent shampooing due to the use of various hairdressing agents and air pollution. Many efforts have been made to restore damaged hair to frequent chemical treatments and shampooing, but the results have been small. This is because the composition of hair is different from other physiological tissues and is dead tissue, so the recovery of damaged parts is limited.

For example, in order to prevent and improve such hair damage, a conditioner has been mainly used. The conditioner mainly contains long-chain quaternary ammonium compounds and higher fatty alcohols, hydrocarbon oils, and silicone oils. The above-mentioned long-chain quaternary ammonium cationic surfactants and higher fatty alcohols and hydrocarbon oils can provide luster, moisturization, and softness to hair. Silicone oil is used to reduce the dryness of hair caused by the elimination of sebum after shampooing, and artificially imparts sebum-like It is used to feel and soften hair.

Moisturizing the hair is formed by the moisture inside the hair and the moisture on the surface of the hair. The softness of the hair is determined by the moisture inside the hair, and the degree of moistness is determined by the moisture on the surface of the hair. However, since the moisture contained in the hair is in equilibrium with the outside of the hair, it is greatly affected by the external environment, that is, temperature, humidity, ultraviolet rays, and the like. Therefore, if the moisture content in the initial stage and the moisture contained in the hair cannot be effectively stored, the hair may become dry, fluffy, and rough.

At normal temperature and pressure (25 ° C, 1 atmosphere), the hair has an average moisture content of about 20%, and the moisture content changes according to the relative humidity of the hair by 3 to 34%. Hair has a structural specificity due to the dense formation of a lipid film consisting of lipids on the surface of the epidermis and a structure mainly composed of proteins called the epidermis. Therefore, the water in the hair memory exists in two physical properties. In hair (see C. Barba, et . Al., Thermochimica Acta , 494: 136-140, 2009). This is divided into surface water (External Water) and internal water (Internal Water). Surface water is the water that will evaporate when heated at 65 ° C for 40 minutes. The non-covalent bonds are mainly present on the surface of the hair. When heated at 180 ° C for 20 minutes, the amino acids that form proteins with the hair will evaporate to stabilize the existing moisture with ionic bonds.

In order to understand the characteristics of these hair moisture and effectively moisturize the dry hair damaged by decolorization treatment and styling, environment (UV, haze), it is urgent to develop a composition to find the control of surface moisture and internal moisture, respectively. The material can improve the elasticity, smoothness and softness of the hair by improving the moisture retention ability of the hair's internal moisture and surface moisture, and eliminate the discomfort of the dry hair of the user.

In the past, most of the moisturizing mechanisms used substances that have a high affinity for water inside the hair, such as proteins or protein derivatives, to retain moisture, and then used moisturizers and emollients outside the hair. And moisture evaporation preventive agents such as Humectant, to achieve moisturization. However, although this method keeps the hair moisture to some extent, it is impossible to completely prevent moisture evaporation, and the moisture inside the hair will still form a balance with the moisture outside. Therefore, it is affected by the external environment such as temperature, humidity, and ultraviolet rays, and there is a problem that it is difficult to effectively achieve hair moisturization.

Macadamia Nut Oil (Macadamia Ternifolia Seed Oil) is a vegetable oil extracted from macadamia nuts harvested in Australia, Hawaii, Brazil, South Africa, Israel, etc. It has the characteristics of colorless or bright yellow, odorless and not easily oxidized. More than 80% of the total weight is monounsaturated fatty acids.

Oleic acid, the main component of macadamia oil, has skin anti-aging activity, and palmitic acid (palmitoleic acid), which accounts for about 20% by weight of macadamia oil, is also found in animals and is composed of animal skin. An essential component of Sebum.

It has been reported that palmitic acid, which accounts for about 22% by weight of the lipid component contained in human skin, together with palmitic acid, occupies about half of the skin's sebum, and has lubricating and softening effects. And protection of protein structure.

In particular, palmitoleic acid as a carrier and softener has excellent dispersibility and permeability, excellent absorption capacity, and is gentle and non-sticky when used on the skin. It acts very gently on the skin, prevents skin aging, and causes blood. Or the flow of lymph fluid is active, protecting the skin from free radicals. Palmitoleic acid is a supplement for reducing palmitoleic acid in the skin during skin aging. It can be used in cosmetic formulations such as creams to help maintain the skin ’s Lipidmantel, which makes the skin smooth and easily absorbed into the skin. Therefore, it can also be used for whole body massage, suitable for all skin types, especially suitable for dry skin or skin with reduced skin elasticity and reduced moisturizing power.

The cosmetic composition containing macadamia oil is not limited in terms of formulation. However, various ingredients may be appropriately contained in a general cosmetic composition depending on various dosage forms or end purposes. Taking cosmetic dosage forms as an example, a hair conditioner (Emollient) containing about 5-10% by weight of macadamia oil can be used as an anti-aging supplement or a sunscreen agent, and about 2-10% by weight of macadamia oil is used. As a lipstick formulation, macadamia oil can be used as a baby oil or massage oil at 100% by weight, and macadamia oil can be used as a carrier for essential oils for aromatherapy. Macadamia oil can be used as a carrier An alternative to mineral oil or jojoba oil for creams or toners.

Under such a technical background, the present inventors have developed an excellent hair moisturizing ability improving cosmetic that can maintain long-term moisturization without being affected by external environments such as temperature, humidity, and ultraviolet rays, and can maintain high softness and moisturization for a long time. As a result of intensive research on the composition, it was found that a cosmetic composition containing arginine, hyaluronic acid, and macadamia oil as an effective ingredient for improving the moisturizing power of the hair increases the amount of water in the hair and suppresses the water in the hair. The effect of improving the retention capacity of the internal moisture of the hair and increasing the retention time of the internal moisture of the hair is obtained, thereby completing the present invention.

An object of the present invention is to provide a cosmetic composition containing a mixture of arginine, hyaluronic acid and macadamia oil as an active ingredient for improving hair moisturizing power.

Another object of the present invention is to provide a cosmetic composition containing a mixture of arginine, hyaluronic acid and macadamia oil as an active ingredient for improving the moisturizing power of damaged hair.

Another object of the present invention is to provide a cosmetic prepared from the above-mentioned cosmetic composition.

In order to achieve the above object, the present invention provides a cosmetic composition containing a mixture of arginine, hyaluronic acid, and macadamia oil as an active ingredient for improving hair moisturizing power, and preferably for improving moisturizing power of damaged hair.

Moreover, this invention provides the cosmetics prepared from the said cosmetics composition.

In addition, the present invention provides the use of a mixture of arginine, hyaluronic acid and macadamia oil as a hair moisturizing improver in the preparation of a cosmetic composition or a cosmetic for improving hair moisturizing power.

Invention effect

According to the present invention, a cosmetic composition containing a mixture of arginine, hyaluronic acid, and macadamia oil as an active ingredient for improving the hair, preferably the moisturizing power (moisturizing power) of the damaged hair, by increasing the Moisture content and suppression of evaporation of moisture in the hair have the effects of increasing the retention of moisture in the hair and increasing the retention time of the moisture in the hair.

Unless defined otherwise, all technical and scientific terms used in this specification have the same meanings as those commonly understood by experts skilled in the technical field to which this invention belongs. In general, the nomenclature used in this specification is well known and commonly used in the art.

The term "about" used in the present specification to indicate concentration, volume, or weight means that there is a maximum allowable error of 10% in the corresponding value or range of values.

In one embodiment of the present invention, in order to confirm the effect of arginine or hyaluronic acid on increasing the amount of water in the hair, the damaged dry hair is treated with arginine or hyaluronic acid to determine the amount of water in the hair. Variety. The results are shown in Fig. 1 and Table 1. It can be confirmed that arginine or hyaluronic acid has an effect of increasing the amount of water in the hair in an appropriate effective content, especially when treated with arginine at 100 ppm or more or at 1000 ppm. Compared with the control group (untreated damaged dry hair), the above-mentioned hyaluronic acid-treated damaged dry hair has a statistically significant increase in the internal moisture content of the hair (refer to Test Example 1).

In another embodiment of the present invention, in order to confirm the effect of free fatty acids on the moisture content of the hair surface, the damaged dry hair is treated with the free fatty acid, and then the change of the moisture content on the hair surface is confirmed. The results are shown in Fig. 2 and Table 2. It can be confirmed that palmitoleic acid has a significant effect on increasing the moisture content on the surface of the hair in an appropriate effective content, and in particular, it has an increase compared with the control group (untreated damaged dry hair). The amount of water on the surface of the hair (see Test Example 2).

In another embodiment of the present invention, in order to confirm that a high content of vegetable oil contains palmoleic acid (Palmitoleic acid, cis-9-hexadecenoic, 16: 1 (n-7); molecular weight 254.4Da; melting point 0.5 ° C) macadamia nuts The effect of oil on the moisture content of the hair surface. After treatment of damaged dry hair with macadamia oil, changes in the moisture content on the hair surface were confirmed. The results are shown in Fig. 3 and Table 4. It can be confirmed that macadamia oil has the effect of increasing the moisture content on the surface of the hair in an appropriate effective content. In particular, damaged dry hair treated with macadamia oil above 10 ppm and the control group (Untreated damaged dry hair) compared to a statistically significant increase in hair surface moisture. On the other hand, as shown in Table 4, even if the damaged dry hair was treated with macadamia oil with a final concentration of 10 ppm, 100 ppm, 1000 ppm, or 10000 ppm, the moisture content in the hair was hardly changed (refer to Test Example 3).

Among the high-vegetable palm oil-containing vegetable oils are not only macadamia oil (19.3% by weight), but also avocado oil (7.5% by weight), olive oil (2.5% by weight), and coconut oil (1.5% by weight). Coral tung oil (Jatropha) (1.5% by weight), almond oil (1.0% by weight), jojoba oil (1.0% by weight), etc. (see Jang et al., J Plant Biotechnol , 37: 25-46 , 2010), using avocado oil, olive oil, coconut oil, coral oil tung oil, almond oil, jojoba oil and other oils containing palm oleic acid as a substitute or supplement for macadamia oil can be used in the present invention In the mixture.

In yet another embodiment of the present invention, in order to confirm the effect of a mixture of arginine, hyaluronic acid and macadamia oil on the hair moisture content, arginine, hyaluronic acid and macadamia are used for damaged dry hair. After the treatment of the oil mixture, changes in the moisture content in the hair were confirmed. The results are shown in Fig. 4 and Table 5. It can be confirmed that a mixture of arginine, hyaluronic acid and macadamia oil has an effect of increasing the amount of water in the hair at an appropriate effective content. Amino acid, hyaluronic acid, and macadamia oil are mixed at the same ppm concentration. When 100 ppm of arginine, 1000 ppm of hyaluronic acid, and 10 ppm of macadamia oil are mixed and used, it can be confirmed that the moisture content in the hair is statistically significantly increased. Synergistic effect is high. In addition, as shown in FIG. 5 and Table 6, it was confirmed that the mixture of arginine, hyaluronic acid, and macadamia oil was statistically significantly increased compared to the mixture of arginine and hyaluronic acid (two mixed groups). The synergistic effect of the moisture content in the hair is high (refer to Test Example 4).

In another embodiment of the present invention, in order to confirm the effect of more than one of arginine, hyaluronic acid and macadamia oil on the surface moisture of hair, arginine, hyaluronic acid and After processing more than one of macadamia oils, the change in the moisture content on the hair surface was confirmed. The results are shown in Fig. 6 and Table 6. It can be confirmed that the mixture of arginine, hyaluronic acid and macadamia oil has the effect of increasing the moisture content on the hair surface in an appropriate effective content. In particular, arginine, hyaluronic acid Compared with a mixture of macadamia nut oil and a mixture of arginine and hyaluronic acid (two mixed groups), it was confirmed that the synergistic effect of statistically significantly increasing the moisture content on the hair surface was high (refer to Test Example 5).

Therefore, one aspect of the present invention relates to a cosmetic composition containing a mixture of arginine, hyaluronic acid, and macadamia oil as an active ingredient for improving the moisturizing power of hair, preferably damaged hair.

The arginine (Arginine, Arg) is transparent at normal temperature and exists in a liquid phase state. It is an amino acid added to perfumes, hair care agents, skin care agents, etc., and contains about 10 in the cosmetic composition according to the present invention. ~ 10000ppm (about 0.001 ~ 1% by weight), preferably about 100 ~ 1000ppm (about 0.01 ~ 0.1% by weight).

The above-mentioned hyaluronic acid (Hyaluronic Acid, Hyaluronan, HA) is transparent at normal temperature and exists in a liquid phase state. It is a substance added to a scalp protector, a hair improver, etc., and is contained in the cosmetic composition according to the present invention. 100 to 100,000 ppm (about 0.01 to 10% by weight), preferably about 1,000 to 10,000 ppm (about 0.1 to 1% by weight).

The above Macadamia Nut Oil is transparent or yellow at normal temperature and exists in a liquid phase state. It is a well-known substance containing a large amount of palmitoleic acid. The cosmetic composition according to the present invention contains about 1 to 1000 pm (about 0.0001 ~ 0.1% by weight), preferably about 10 ~ 100pm (about 0.001 ~ 0.01% by weight).

The mixture of arginine, hyaluronic acid and macadamia oil contained in the cosmetic composition according to the present invention is based on ppm concentration of arginine, hyaluronic acid and macadamia oil, based on 80 ~ 120: 800 ~ 1200: 8 ~ 12 (ie, 8 ~ 12: 80 ~ 120: 0.8 ~ 1.2), preferably 90 ~ 110: 900 ~ 1100: 9 ~ 11 (ie, 9 ~ 11: 90 ~ 110: 0.9 ~ 1.1) , The best is 10: 100: 1. The mixture is mixed with arginine, hyaluronic acid, and macadamia oil in a weight ratio (% by weight) corresponding to the mixing ratio of the ppm concentration.

In the present invention, the dosage form stability and the cosmetic method limit of a cosmetic composition containing a mixture of arginine, hyaluronic acid and macadamia oil are taken into consideration. The mixing ratio of the acid and macadamia oil (ppm concentration standard) is maintained at 80 ~ 120: 800 ~ 1200: 8 ~ 12, preferably 90 ~ 110: 900 ~ 1100: 9 ~ 11, and optimal 10: 100: 1 Below, based on the total weight of the composition, it contains 0.09% by weight or less, preferably 0.01 to 0.09% by weight, more preferably 0.01 to 0.05% by weight, and neutralizes arginine (arginine stock solution) so that the pH does not change. Exceeded the cosmetic limit of pH 9.0. The content of hyaluronic acid in the above mixture keeps the mixing ratio (ppm concentration standard) of arginine, hyaluronic acid and macadamia oil at 80 ~ 120: 800 ~ 1200: 8 ~ 12, preferably 90 ~ 110: 900 In a state of ~ 1100: 9 ~ 11, optimal 10: 100: 1, based on the total weight of the composition, it contains 0.9% by weight or less, preferably 0.1 ~ 0.9% by weight, and more preferably 0.1 ~ 0.5% by weight. The content of macadamia oil in the above mixture varies according to the dosage form of the composition. The above composition is a wash-off hair care formulation or a leave-on: after applying to the hair, there is no need to wash or wipe with water. Directly applied method) The content of macadamia oil when maintaining hair formulations, keeping the mixing ratio (ppm concentration standard) of arginine, hyaluronic acid and macadamia oil at 80 ~ 120: 800 ~ 1200: 8 ~ 12 In the state of preferably 90 to 110: 900 to 1100: 9 to 11, and most preferably 10 to 100: 1, based on the total weight of the composition, it contains 0.009% by weight or less, preferably 0.001 to 0.009% by weight, more Better 0.001 ~ 0.005% by weight.

In the present invention, when the content of the above-mentioned mixture is less than about 0.1% by weight (about 1000ppm) based on the total weight of the cosmetic composition, the hair moisturizing effect is not obvious, and when it exceeds about 1.0% by weight (10000ppm), the content increases. The effect is not greatly increased, so the above-mentioned mixture contains 0.1 to 1.0% by weight (1000 to 10000ppm), preferably 0.1 to 0.5% by weight (1000 to 5000ppm), and more preferably 0.1 to 0.2% by weight based on the total weight of the composition. % (1000 ~ 2000ppm), the best 0.111% by weight (1110ppm).

In the present invention, the above composition can increase the external water content of the hair, preferably damaged hair.

In the present invention, the above composition can increase the internal water content of hair, preferably damaged hair.

In the present invention, the damaged hair is caused by more than one type of chemical treatment, physical damage, stress, or lack of nutrition selected from the group consisting of dyed hair and perm.

The surface moisture content of the hair occupies about 75% of the hair moisture content, and varies greatly depending on the relative humidity (Relative Humidity, RH), pH, and temperature of the hair exposure environment.

The surface moisture of the hair is moisture lost by evaporation at a temperature of about 65 ° C. or higher, and mainly exists in the cell membrane complex (Cell Membrane Complex; CMC) of the hair.

The internal moisture content of the hair accounts for about 25% of the hair moisture content, and there is almost no change in the moisture content within the range of 25 to 95% of the relative humidity (RH) of the hair exposure environment.

The internal moisture of the hair is moisture lost by evaporation at a temperature of about 180 ° C. or higher, and exists in a state in which hydrogen is bonded to amino acids in the interlamellar space of the hair.

In the present invention, the above-mentioned composition is used for suppressing water volatilization of damaged hair and for improving moisturizing power.

In the present invention, the damaged hair is caused by one or more types of chemical treatment, physical damage, stress, or lack of nutrition selected from the group consisting of dyed hair and perm, but it is not limited thereto.

In the present invention, the above-mentioned cosmetic composition is not particularly limited in dosage form, and may be an ointment, a nutritional lotion for hair, a massage cream for hair, a hair mask, a hair growth oil, a hair cream, a conditioner, an ointment, and a scalp treatment. Cosmetic composition in dosage forms such as creams, shampoos, and hair waxes. These cosmetic compositions of each dosage form may appropriately contain various ingredients mixed in a general cosmetic composition according to the aforementioned various dosage forms or the final purpose, and the types and amounts of these ingredients can be easily selected by those skilled in the art.

In the present invention, the aforementioned cosmetic composition may be mixed with other ingredients mixed in ordinary cosmetics. In this case, as the mixed ingredients, oil and fat ingredients, humectants, hair conditioners, surfactants, organic and inorganic pigments, organic powders, ultraviolet absorbents, preservatives, fungicides, antioxidants, plant extracts, and pH adjusters can be used. , Alcohol, pigment, fragrance, blood circulation promoter, cooling agent, antiperspirant, purified water, etc.

The present invention is further described in detail through the following examples. These embodiments are only for illustrating the present invention, and those with ordinary knowledge in the art naturally understand that the scope of the present invention is not limited to these embodiments.

Test Example 1: Evaluation of the effect of arginine or hyaluronic acid on hair moisturizing power by measuring the amount of water in the hair

In order to confirm the effect of arginine or hyaluronic acid on increasing the amount of water in the hair, damaged dry hair was treated with arginine or hyaluronic acid, and then the thermogravimetric assay was used to determine the amount of water in the hair. Variety.

"Test Object"

Normal hair : As standard hair, normal black hair with a length of 10 cm (Tress, BM-B10, Beaulax, Japan).

Damaged dry hair : After the above normal hair is decolorized with a decolorizer (first agent: second agent in a 3: 1 mixture for 30 minutes), use a shampoo (Amos shampoo, Amore) Treated, washed with water at a temperature of 30 ° C for 3 minutes, and dried (at a surface temperature of the hair of 50 ° C or lower, dried for 10 minutes) to obtain damaged dry hair.

《Reagents for Hair Treatment》

Hair treatment reagent 1 : using arginine stock solution (obtained by dissolving arginine powder (manufacturer: Shiyi) in water) to a final concentration of 10 ppm (about 0.001% by weight), 100ppm (about 0.01% by weight), 1000 ppm (about 0.1% by weight) and 10,000 ppm (about 1% by weight) were used to treat the hair of the test article.

Hair treatment reagent 2 : Use hyaluronic acid stock solution (obtained by dissolving sodium hyaluronate crosspolymer (manufacturer: Nebula Bio) in water) to a final concentration of 10 ppm (0.001% by weight) and 100ppm (0.01% by weight) %), 1000 ppm (0.1% by weight), and 10,000 ppm (1% by weight), the hair of the test article was treated.

Control group : Water or alkyl benzoate (Alkyl Benzoate (사 보덤 ^TM ))) was used to treat the hair of the test article with a volume of 100 μl.

《Hair Treatment Method》

Apply (treat) arginine (reagent for hair treatment 1) or hyaluronic acid (reagent for hair treatment 2) at a concentration of 10ppm, 100ppm, 1000ppm, or 10000ppm to damaged dry hair (refer to "Test Article"). Packed in a plastic bag to minimize exposure to outside air (refer to Table 1 below for the treatment concentration of hair treatment reagents for test objects).

"Hair moisturizing power measurement method: Thermogravimetric assay"

Moisture meter (MS-70, A & D, Japan) to measure the moisture content of hair (normal hair without treatment; damaged dry hair without treatment; damaged dry hair treated with arginine or hyaluronic acid) (measurement Moisture content of three samples (triplicate samples) of each reagent, and average values were calculated. At this time, the moisture content of the hair was measured at two temperatures of 65 ° C (Procedure 5) and 180 ° C (Procedure 3). The moisture content of the hair was measured until the moisture content of the hair was 0.02% (w / w), measuring the cumulative moisture evaporation [% (w / w)] for 3 to 30 minutes (refer to C. Barba, et . al., Thermochimica Acta , 494: 136-140, 2009; Yash Kamath, et . al., J. Cosmet. Sci. , 65: 37-48, 2014; Clarence R. Robbins, Chemical and Physical Behavior of Human Hair , Chapter, 2.10 "Water: A Fundamental Component of Human Hair", 5th Edition, 2010).

Table 1 below shows the results of confirming changes in the surface moisture content and the internal moisture content of hair treated with arginine or hyaluronic acid by a thermogravimetric assay. Table 1

The results are shown in Fig. 1 and Table 1. It can be confirmed that arginine or hyaluronic acid has an effect of increasing the amount of water in the hair in an appropriate effective content, especially when treated with arginine at 100 ppm or more or at 1000 ppm. Compared with the control group (untreated damaged dry hair), the above hyaluronic acid-treated damaged dry hair significantly increased the internal moisture content of the hair.

Test Example 2: Evaluation of the effect of free fatty acids on hair moisturizing power by measuring the surface moisture content of hair

In order to confirm the effect of free fatty acids on the hair surface moisture, damaged dry hair was treated with different types of free fatty acids, and then the thermogravimetric assay (Thermogravimetric assay; see Test Example 1) was used to confirm the changes in the hair surface moisture. [Control group: Alkyl Benzoate (사 보덤 ^c )]].

Table 2 below shows the results obtained by measuring the changes in the surface moisture content and the internal moisture content of the hair treated with the free fatty acid by a thermogravimetric assay (measurement of the moisture content of three samples of each reagent to obtain an average value). Table 2

The results are shown in Figure 2 and Table 2. It can be confirmed that palmitoleic acid has a significant effect on increasing the moisture content on the surface of the hair in an appropriate effective content, especially compared with the control group (untreated damaged dry hair), which increases the hair Surface moisture.

Test Example 3: Evaluation of the effect of macadamia oil on hair moisturizing power by measuring the surface moisture content of hair

In order to confirm the effect of macadamia oil containing palmitolic acid in the vegetable oil on the moisture content of the hair surface, damaged dry hair was treated with macadamia oil and then subjected to thermogravimetric analysis (refer to Test Example 1) ) Confirm the change in the moisture content on the hair surface [control group: Alkyl Benzoate (사 보덤 ^TM )].

《Reagents for Hair Treatment》

Hair treatment reagent 3: Use Macadamia Nut Oil stock solution (Macadamia Integrifolia Seed Oil) or Macadamia Ternifolia Seed Oil (manufacturer: ADM, B & H Tech) was dissolved in Alkyl Benzoate (manufacturer: 사 보덤 ^TM ) to a final concentration of 10 ppm (0.001% by weight), 100ppm (0.01% by weight), 1000ppm (0.1% by weight) And 10000 ppm (1% by weight), the hair of the test article was treated.

Here, the test article, the hair treatment control group, the hair treatment method, and the hair moisturizing power measurement method are the same as those in Test Example 1.

The above-mentioned hair treatment reagent 3 or a vegetable oil contained in a mixture of arginine, hyaluronic acid, and a vegetable oil described later uses macadamia oil having a high content of palmitic acid containing free fatty acids.

The composition of free fatty acids contained in the macadamia oil stock solution (manufacturer: B & H Tech) used in the present invention is shown in Table 3 below. The content of palmitic acid in the above-mentioned stock solution is 15.0 to 22.0% by weight. table 3

Table 4 below shows the results of confirming the changes in the surface moisture content and the internal moisture content of hair treated with macadamia oil by using a thermogravimetric assay (measurement of the moisture content of three samples of each reagent to obtain an average value). Table 4

The results are shown in Fig. 3 and Table 4. It can be confirmed that macadamia oil has the effect of increasing the moisture content on the surface of the hair in an appropriate effective content. In particular, damaged dry hair treated with macadamia oil above 10 ppm and the control group (Untreated damaged dry hair) compared to a statistically significant increase in hair surface moisture.

On the one hand, as shown in Table 4, even if the damaged dry hair was treated with macadamia oil having a final concentration of 10 ppm, 100 ppm, 1000 ppm, or 10000 ppm, the moisture content in the hair remained almost unchanged.

Test Example 4: Evaluation of the effect of a mixture of arginine, hyaluronic acid and macadamia oil on the moisturizing power of hair by measuring the internal moisture content of the hair

In order to confirm the effect of using more than one of arginine, hyaluronic acid, and macadamia oil to treat the hair's moisture content in the hair, use more than one of arginine, hyaluronic acid, and macadamia oil on damaged dry hair. After the treatment, a change in the moisture content in the hair was confirmed using a thermogravimetric assay (refer to Test Example 1). The concentrations of the above-mentioned arginine, hyaluronic acid, and macadamia oil were the most appropriate concentrations confirmed in Test Examples 1 and 3.

Here, the test article, the control group for hair treatment, the hair treatment method, and the hair moisturizing power measurement method are the same as those in Test Example 1. A mixture of arginine, hyaluronic acid, and macadamia oil is used in the preparation of a hair treatment reagent. Arginine stock solution, hyaluronic acid stock solution, and macadamia oil stock solution (refer to Test Examples 1 and 3), prepared by diluting with water, so that the final mixing ratio of arginine, hyaluronic acid, and macadamia oil (ppm concentration standard) ) 1: 1: 1 (ie, "10ppm arginine + 10ppm hyaluronic acid + 10ppm macadamia oil" reagent; "100ppm arginine + 100ppm hyaluronic acid + 100ppm macadamia oil" reagent; "1000ppm arginine + 1000ppm hyaluronic acid + 1000ppm macadamia oil "reagent), 10: 10: 1 (i.e.," 100ppm arginine + 100ppm hyaluronic acid + 10ppm macadamia oil "reagent) and 10: 100: 1 (i.e.," 100ppm arginine + 1000ppm hyaluronic acid + 10ppm macadamia oil "reagent), and then apply (treatment) each of the above mixtures to damaged dry hair (refer to" Test Items "), put them in a plastic bag, Minimal exposure to air (Test article treated with the hair treatment agent concentration reference to the following Table 5).

Table 5 below shows the results of confirming changes in the surface moisture content and the internal moisture content of hair treated with a mixture of arginine, hyaluronic acid, and macadamia oil using a Thermogravimetric assay (three samples of each reagent were measured) Moisture content, find the average). table 5

The results are shown in Fig. 4 and Table 5. It can be confirmed that a mixture of arginine, hyaluronic acid and macadamia oil has an effect of increasing the amount of water in the hair at an appropriate effective content. Amino acid, hyaluronic acid, and macadamia oil are mixed at the same ppm concentration. When 100 ppm of arginine, 1000 ppm of hyaluronic acid, and 10 ppm of macadamia oil are mixed and used (Example 1), a statistically significant increase can be confirmed. The synergistic effect of the moisture content in the hair is high (damaged dry hair compared with the untreated group * p <0.05, ** p <0.01, *** p <0.001).

In addition, Table 6 below shows the results of measuring changes in the surface moisture content and the internal moisture content of hair treated with one or more of arginine, hyaluronic acid, and macadamia oil using a thermogravimetric assay (measurement of each reagent Of the three samples, and averaged). Table 6

The results are shown in Figure 5 and Table 6. The mixture of arginine, hyaluronic acid and macadamia oil (Example 1) and the mixture of arginine and hyaluronic acid (two mixed groups: Comparative Example 8) were in phase. It can be confirmed that the synergistic effect of statistically significantly increasing the amount of water in the hair is high.

Test Example 5: Evaluation of the effect of a mixture of arginine, hyaluronic acid and macadamia oil on hair moisturizing power by measuring the surface moisture content of hair

In order to confirm the effect of using more than one of arginine, hyaluronic acid and macadamia oil to treat the hair surface moisture, the damaged dry hair was used of more than one of arginine, hyaluronic acid and macadamia oil. After the treatment, a change in the moisture content on the surface of the hair was confirmed using a thermogravimetric assay (refer to Test Example 1). The concentrations of the above-mentioned arginine, hyaluronic acid, and macadamia oil were the most appropriate concentrations confirmed in Test Examples 1 and 3.

Here, the test article, the control group for hair treatment, the hair treatment method, and the hair moisturizing power measurement method are the same as those in Test Example 1. The mixture of arginine and hyaluronic acid is arginine used in the preparation of a reagent for hair treatment. The stock solution and the hyaluronic acid stock solution (refer to Test Example 1) were prepared by diluting with water, so that the final mixing ratio (ppm concentration standard) of arginine and hyaluronic acid was 1:10 (that is, "100 ppm arginine + 1000 ppm hyaluronic acid "Reagents"; the mixture of arginine, hyaluronic acid and macadamia oil is the arginine stock solution, hyaluronic acid stock solution and macadamia oil stock used in the preparation of hair treatment reagents (refer to Test Example 1 and Test Example 3), prepared by dilution with water, so that the final mixing ratio (ppm concentration reference) of arginine, hyaluronic acid and macadamia oil is 10: 100: 1 (that is, "100ppm arginine + 1000ppm hyaluronic acid + 10ppm macadamia Oil "reagent), and then apply (treatment) each of the above mixtures to damaged dry hair (refer to" Test Items ") and put them in a plastic bag to minimize exposure to external air (to the test object Treated hair treated with the reagent concentration reference table 6).

The results are shown in Fig. 6 and Table 6. It can be confirmed that the mixture of arginine, hyaluronic acid and macadamia oil has the effect of increasing the moisture content on the hair surface in an appropriate effective content. In particular, arginine, hyaluronic acid Compared with a mixture of macadamia oil (Example 1) and a mixture of arginine and hyaluronic acid (two mixed groups: Comparative Example 8), it was confirmed that the synergistic effect of statistically significantly increasing hair surface moisture was high .

"Statistical Processing"

The statistical analysis in Examples 1 and 3 to 5 is a survey of the significant differences between the two groups. Compared with the control group using t-test identification method, * P <0.05, ** P <0.01, *** When P &lt; 0.001, the difference was considered valid.

It can be confirmed by comprehensively considering the results of Test Examples 1 to 5 that arginine, hyaluronic acid and Australia are used compared with arginine, hyaluronic acid and macadamia oil alone, or a mixture of arginine and hyaluronic acid. When blended with nut oil, it significantly increases the amount of water in the hair and significantly improves the moisturizing power of the hair.

Formulation example 1: ointment

The ingredients of Table 7 including the oil phase component and the water phase component were mixed to prepare an ointment containing a mixture of arginine, hyaluronic acid, and macadamia oil of the present invention. Table 7

Formulation Example 2: Hair Toner

The ingredients in Table 8 including the oil phase component and the water phase component were mixed to prepare a nutritional lotion for hair containing a mixture of the arginine, hyaluronic acid, and macadamia oil of the present invention. Table 8

Formulation Example 3: Massage Cream for Hair

The ingredients of Table 9 including the oil phase component and the water phase component were mixed to prepare a massage cream for hair containing a mixture of arginine, hyaluronic acid, and macadamia oil of the present invention. Table 9

Formulation Example 4: Hair Mask

The ingredients of Table 10 including the oil phase component and the water phase component were mixed to prepare a hair film containing a mixture of arginine, hyaluronic acid, and macadamia oil of the present invention. Table 10

Formulation example 5: hair growth oil

A hair growth oil containing a mixture of arginine, hyaluronic acid, and macadamia oil according to the present invention was prepared according to the composition described in Table 11. Table 11

Formulation Example 6: Hair Cream

A hair milk containing a mixture of arginine, hyaluronic acid, and macadamia oil according to the present invention was prepared according to the composition described in Table 12. Table 12

Formulation example 7: conditioner and tincture ointment

According to the composition described in Table 13, a conditioner and a tincture ointment containing a mixture of the arginine, hyaluronic acid, and macadamia oil of the present invention were prepared by a usual method. Table 13

Formulation Example 8: Shampoo

The ingredients of Table 14 including the oil phase component and the water phase component were mixed to prepare a shampoo containing a mixture of arginine, hyaluronic acid, and macadamia oil of the present invention. Table 14

The specific parts of the content of the present invention have been described in detail above. Those with ordinary knowledge in the art should understand that these specific technologies are only preferred embodiments, and the scope of the present invention is not limited thereto. Therefore, the essential scope of the present invention is defined according to the scope of the attached patent application and its equivalent.

Fig. 1 shows the change in the moisture content in the hair of damaged dry hair treated with arginine or hyaluronic acid (atlas: Mean (Mean) ± standard error of measurement (SEM)). FIG. 2 shows the change in the moisture content on the hair surface of damaged dry hair treated with free fatty acids (atlas: Mean (Mean) ± standard error of measurement (SEM)). FIG. 3 shows the change in the moisture content on the hair surface of damaged dry hair treated with macadamia oil (atlas: mean (Mean) ± standard error of measurement (SEM)). FIG. 4 shows the change in the moisture content in the hair of damaged dry hair treated with a mixture of arginine, hyaluronic acid and macadamia oil (atlas: Mean (Mean) ± standard error of measurement (SEM)). FIG. 5 shows changes in moisture content in hair of damaged dry hair treated with more than one of arginine, hyaluronic acid, and macadamia oil (atlas: mean (Mean) ± standard error of measurement (SEM)). FIG. 6 shows the change in the moisture content on the hair surface of damaged dry hair treated with more than one of arginine, hyaluronic acid, and macadamia oil (atlas: mean (Mean) ± standard error of measurement (SEM)).

Claims (9)

A cosmetic composition for improving hair moisturizing power. The cosmetic composition for improving hair moisturizing power contains a mixture of arginine, hyaluronic acid, and macadamia oil as an active ingredient. The cosmetic composition for improving hair moisturizing power as described in item 1 of the scope of patent application, wherein the mixture is a mixture of arginine, hyaluronic acid, and macadamia oil with a ppm concentration of 80 ~ 120: 800 ~ 1200: 8 ~ 12 for mixing. The cosmetic composition for improving hair moisturizing power as described in item 1 of the scope of patent application, wherein the content of the mixture is 0.1 to 1.0% by weight relative to the total weight of the composition. The cosmetic composition for improving the moisturizing power of hair according to item 1 of the scope of the patent application, wherein the composition increases the surface moisture content of the hair. The cosmetic composition for improving the moisturizing power of hair according to item 1 of the scope of patent application, wherein the composition increases the amount of internal water in the hair. The cosmetic composition for improving the moisturizing power of hair according to item 1 of the scope of the patent application, wherein the composition is used for suppressing water volatilization of damaged hair and improving the moisturizing power of damaged hair. The cosmetic composition for improving hair moisturizing power as described in item 6 of the scope of patent application, wherein the damaged hair is one or more selected from the group consisting of dyed hair and perm, chemical treatment, physical damage, pressure, Or caused by lack of nutrition. The cosmetic composition for improving hair moisturizing power as described in item 1 of the scope of the patent application, wherein the composition is formulated into a composition selected from the group consisting of ointment, nutritional lotion for hair, massage cream for hair, hair mask, hair oil, One of the group consisting of hair cream, conditioner, tincture, scalp treatment, shampoo and hair wax. Use of a mixture of hyaluronic acid and macadamia oil as a hair moisturizing improver in the preparation of a cosmetic composition or a cosmetic for improving hair moisturizing power.