TW201808099A - A synergistic fungicidal composition and use thereof - Google Patents

Abstract

A synergistic fungicidal composition is provided, the composition comprising: (A) the crystalline modification II of 3-pyridinecarboxamide, 2-chloro-N-(4'chloro[1,1'biphenyl]-2-yl) (boscalid); and (B) the crystalline modification IV of methyl N-{2-[1-(4-chlorophenyl)-1H-pyrazol-3-yloxymethyl]phenyl} (N-methoxy)carba mate (pyraclostrobin). A method of treating fungal infestations in plants and plant materials is also provided.

Description

   Synergistic fungicidal composition and use thereof   

The present invention relates to a synergistic fungicidal composition. The composition finds use in preventing and / or treating fungal infections in plants and plant parts. The invention also relates to methods for preventing and / or treating fungal infections in plants and plant parts.

There is a continuing need to develop compounds that improve fungicidal activity to protect crops. In addition, experience with single-active direct formulation fungicides based around the world shows that the risk of resistance development is very high. Resistance to increasing numbers of pathogens in field crops, fruits, vegetables, etc. has been reported worldwide. Mixing of different fungicides can help reduce antagonistic selection pressure in target pathogens.

The compound 2-chloro-N- (4'chloro [1,1'biphenyl] -2-yl) -3-pyridinecarboxamide with the general name Becqueride was first described in US 5,330,995. A crystalline modification I of Bacral anhydrous having a melting point from 144 ° C to 145 ° C is known. This variant is discussed in US 7,501,384. Beckley is active as a fungicide and is now commercially available in a range of formulations for treating fungal infections.

We have found it difficult to grind crystalline modification I of Bexcollet anhydrous in water. Therefore, it is not a simple task to directly formulate the crystalline modification I of Bexcollet anhydrous into a formulation requiring a grinding and / or milling process. Such formulations are, for example, granules, capsule granules, tablets, water-dispersible granules, water-dispersible tablets, water-dispersible powders or water-dispersible powders for seed treatment, powder formulations, and the active compounds in which Formulations in dispersed form, such as aqueous suspensions, oil-based suspensions, concentrated suspensions or suspensions for seed treatment. Before formulating as an aqueous suspension, it is necessary to hydrate the crystalline modification I of Beccolide Anhydrous.

It is proposed in US 7,501,384 that the crystalline modification II of Beckley's Anhydrous is more suitable for the manufacture of formulations requiring a grinding / milling process.

Compound N- [2-[[[[1- (4-chlorophenyl) -1H-pyrazol-3-yl] oxy] methyl] phenyl] -N-methoxy Methyl carbamate is a known fungicide. Formulations containing becmin for treating fungal infections in crops are known and are commercially available. US 7,816,392 discloses four different crystalline variants I to IV of Becmin.

We have surprisingly found that the combination of crystalline variant II of Beccolide with crystalline variant IV of Pakmin provides a composition with synergistic activity, i.e. an increase in activity expected from the activity when the two components are applied separately Fungicidal activity.

Therefore, in a first aspect, the present invention provides the following fungicidal composition comprising: (A) 2-chloro-N- (4'chloro [1,1'biphenyl] -2-yl) 3-pyridine Crystalline modification II of sulfonamide (Beckley); and (B) N- {2- [1- (4-chlorophenyl) -1H-pyrazol-3-yloxymethyl] phenyl} ( Crystalline modification IV of N-methoxy) methyl carbamate (Hexamin).

The composition of the invention is particularly useful for preventing and / or treating fungal infections in plants and / or plant parts.

In a second aspect, the invention provides a method for preventing and / or treating fungal infections in plants and / or plant parts, the method comprising applying to the plants and / or plant parts: (A) 2-chloro-N -(4'chloro [1,1'biphenyl] -2-yl) 3-pyridinecarboxamide (beckley) crystal modification II; and (B) N- {2- [1- (4 -Chlorophenyl) -1H-pyrazol-3-yloxymethyl] phenyl} (N-methoxy) carbamic acid methyl ester (Hexamine) IV.

In a further aspect, the present invention provides the use of the following components in the prevention and / or treatment of fungal infections in plants and / or plant parts: (A) 2-chloro-N- (4'chloro [1,1 'associated Phenyl] -2-yl) Crystalline modification II of 3-pyridamidine (Beckley); and (B) N- {2- [1- (4-chlorophenyl) -1H-pyrazole- Crystalline modification IV of 3-yloxymethyl] phenyl} (N-methoxy) carbamate (Pakmin).

The crystalline modification II of Beckley refers to the crystalline modification of Beckley disclosed in US 7,501,384. The crystalline variants I to IV of Becmin refer to the crystalline variants of Becmin disclosed in US 7,816,392.

As used herein, "plant" refers to all plants and plant populations, such as desired and undesired wild plants or crop plants.

As used herein, "plant part" refers to all parts and organs of a plant, such as buds, leaves, needles, stems, stems, fruiting bodies, fruits, seeds, roots, tubers, and rhizomes. Also included are harvested materials, as well as vegetative and reproductive propagation materials such as cuttings, tubers, meristems, rhizomes, stolons, seeds, single and multiple plant cells, and any other plant tissue.

The term "location" refers to the place where the plant grows, where the plant propagation material of the plant is sown, or where the plant propagation material of the plant will be sown.

"At least one" means 1, 2, 3, 4, 5, 6, 7, 8, 9, or more of a plurality of corresponding compounds or components, preferably 1, 2, or 3 of them.

The synergistic fungicidal composition, method and use of the present invention are suitable for treating a wide range of crop plants, including cereals, such as wheat, barley, rye, oats, corn, rice, sorghum, triticale, and related crops; fruits, such as pears Fruits, stone fruits and soft fruits (e.g. apples, pears, plums, peaches, pistachios, edamans, cherries and berries (e.g. grapes, bananas, strawberries, bushberry, cranberry, raspberry and blackberry); beans Plants, such as beans, lentils, peas, and soybeans; oilseed plants, such as canola, mustard, and sunflower; cucurbitaceae, such as cantaloupe, zucchini, cucumber, melon, pumpkin, squash, and watermelon; citrus fruits, Such as orange, lemon, grapefruit and citrus; and vegetables such as spinach, lettuce, asparagus, cabbage, carrot, onion, tomato, potato, red pepper, garlic and shallot; coffee; sugar cane; hops; nuts; and ornamental plants, Examples are flowers (such as roses), shrubs, broad-leaved trees, and evergreens (such as conifers).

The compositions, methods and uses of the present invention are particularly advantageous when applied to cereals, fruits, leguminous plants, oil plants and vegetables.

The compositions, methods and uses of the invention are advantageous when applied to wheat, barley, oats, rice, grapes, bananas, soybeans, rapeseed and vegetables.

The composition, method and use of the present invention can be used in the agricultural sector and related fields of use to prevent and / or treat fungal infections, including but not limited to: cereals: oats: leaf rust (Puccinia coronate var .avenae)); barley: brown spots; common root rot (sporidiomycetes); spotted reticulata, scars (Drechslera / Pyrenophora teres); Leaf spot (Rhynchosporium secalis); Cyanospora leaf spot (Ramularia collo-cygni); Brown rust (Barley stem rust); Powdery mildew (Gramineae) Powdery mildew); wheat: brown spot, blight spot (Ryegrass sclerotinia); leaf / brown rust (wheat rust, Puccinia tritici-duri); wheat spore spot, shell needle Sporosporum (Triticum sp (Wheat stripe rust); Berries: Alternaria leaf spot and fruit rot (Alternaria); Anthracnose (Anthracnose, Elsinoe spp. )); Botrytis cinerea (Botrytis cinerea); leaf spot and scarring (coccus spp., Echinococcus, banana black-spot leaf spot bacteria); Streptococcus spp. (Streptococcus spp.); Phytophthora leaf spot, branch blight, and fruit rot (Phytophthora spp.); Powdery mildew (monofila, birch, and sporozoites); short Withered branches (Didymella spp.), Mal-de-Sigatoka, Sigatoka (Spherical cavity of banana leaves) Bacteria); Banana: Banana leaf spot; Grape: Mycosphaerella angulata; Anthracnose (Elsinoe ampelina); Black rot (Guignardia bidwellii); Downy mildew (Monophytic grape vine); Leaf blight (Pseudocercospora vitis); Phytophthora cane and leaf spot (Grape branch blight); Powdery mildew (Grape powdery mildew); Anthracnose (Anthracis anthracis); Summer fruit rot (acid rot) (Mycosporium and Pythium); Botrytis cinerea (Botrytis cinerea); Soybean: Phakopsora pachyrhizi); scales Vegetables: Botrytis bacterial blight (Botrytis); Botrytis cervicella (Botrytis); Purple spot and leaf blight (Alternaria spp.); Phytophthora leaf blight and stems Rotten (A. swelling); Downy mildew (Peronospora destructor); Carrot: Alternaria leaf spot (Alternaria); Cercospora leaf spot (Ceratium ); Powdery mildew (Erysiphe graminis); Southern root rot (Sclerotium rolfsii); Yichi (yiuch); Cucurbitaceae vegetables: Downy mildew (Pseudomonas pseudocubis); Alternaria Fusarium oxysporum (Sphaerotheca cucurbita); Cercospora citrulina; Fusarium oxysporum (Melon blight); Powdery mildew (Cucumber powdery mildew, Fusarium oxysporum); Anthracnose (Anthracnose ( Collectotrichum orbiculare)); hops: powdery mildew (Pseudomonas aeruginosa, Monochaete); downy mildew (Pseudoperonospora humuli); powdery mildew (Pseudoperonospora, powdery mildew, strawberry powdery mildew) , Monophyla); Pistachios: Alternaria phytophthora (Alternaria); Botrytis fusarium wilt on flowers and shoots (Botrytis cinerea); Ears and shoots Fusarium oxysporum (grape ulcer); pear fruit: Apple spotted leaf disease (Alternaria mali); apple scab (black scab); bitter rot (anthrax); black rot / frog eye Leaf spot (Botryosphaeria obtusa); Penicillium (Penicillium); Brooks spots (Apple black spot); Fly spot (Zygophiala jamaicensis); Botrytis cinerea Disease (Botryosphaeria fungus); Pear melanogaster (M. esculenta); powdery mildew (Pleurotus ostreatus); coal fouling (disease complex); white rot (Botryosphaeria dothidea) Capsin rust (Gymnosporangium juniperi-virginianae); Citrus rust (Gymnosporangium clavipes); Oilseed rape: Phyllostachys (Leptosphaeria maculans); Pale leaf spots (Pyrenopeziza brassicae); Sclerotinia sclerotiorum; Fruits: powdery mildew (Sphaerotheca uniflora; Monochae rosea), scab (Apple scab); stone fruit: chain Spore spot (alternaria); anthracnose (anthrax); flower rot (streptococcus); brown rot ( Streptomyces sclerotiorum); Leaf spot (leaf spot); powdery mildew (monofilamenta, powdery mildew); ripe fruit rot (brown rot fungus, Sclerotinia sclerotiorum, Botrytis cinerea, roots) Mycobacterium); Rust (Tranzschelia discolor); Scab (Cladosporium carpophilum); Wilsonomyces carpophilus; Strawberry: Anthracnose (Anthracnose); Grape Botrytis cinerea (Botrytis cinerea); leaf spot (Fructococcus spp.); Powdery mildew (Fructus powdery mildew); nuts: Alternaria leaf spot (Alternaria); anthracnose (Anthracis) Flower rot (Streptococcus spp.); Eastern hazel blight (Anisogramma anomala); leaf rust (A. heterochromatus); scab (C. caryigenum); Green fruit rot (Botrytis cinerea); cavities (Wilsonomyces carpophilus); Vegetables: Downy mildew (Uniaxial mold); Powdery mildew (Mesporia); Botrytis cinerea (Botrytis cinerea).

The fungicidal composition, method and use of the present invention show amazingly high efficacy in treating and / or preventing fungal diseases caused by fungal pathogens, including: barley: speckles (Drakes sp Leaf spot (Barley moirella); Phyllostachys spp. (Ramularia collo-cygni); Wheat: leaf / brown rust (wheat rust, Puccinia tritici- duri)); wheat shell spores, spores (wheat spores); bacterial blight (polyspore spores); yellow rust (wheat stripe rust); banana: banana black stripe leaf spot ; Grape: Downy mildew (downy mildew); Powdery mildew (grass powdery mildew); Botrytis cinerea (Botrytis cinerea); Soybean: Puccinia striiformis; Oilseed rape: Phyllostachys sp. Coccus spp.); Pale leaf spot (Sclerotinia brassicae); Sclerotinia sclerotiorum; Fruits: powdery mildew (Sphaerotheca uniflora; Monochaete rosea), scab (Apple scab); Downy mildew (Uniaxa); powdery mildew (Mesporia); Botrytis cinerea (Botrytis cinerea).

The composition of the present invention comprises (A) a crystalline modification II of 2-chloro-N- (4'chloro [1,1'biphenyl] -2-yl) 3-pyridamidine (Beckley); And (B) N- [2- [1- (4-chlorophenyl) -1H-pyrazol-3-yloxymethyl] phenyl] (N-methoxy) carbamate (100 Kemin), a crystalline modification IV. The crystalline modification II of Beckley may be present in the synergistic fungicidal composition of the present invention in any suitable amount, and is preferably present in an amount of up to 80% by weight, more preferably in an amount of up to 80% by weight. An amount of up to 70% by weight is present, and even more preferably an amount of up to 60% by weight is present. The crystalline modification II of Becquer may be present in the composition from about 1% to about 80% by weight, preferably from about 1% to about 70% by weight, and more preferably It is present in an amount from about 1% to about 60% by weight of the composition.

The crystalline variant IV of Bacromin may be present in the synergistic fungicidal composition in any suitable amount, and is preferably present in an amount of up to 70% by weight, and more preferably up to 70% by weight. An amount of 60% is present, and even more preferably, an amount of up to 50% is present. The crystalline variant IV of Bacromin may be present in the composition in an amount of from about 1% to about 70% by weight, preferably in an amount of from about 1% to about 60% by weight, and more preferably It is present in an amount from about 1% to about 50% by weight of the composition.

Components (A) and (B) can be used in the composition, method or use of the invention in any suitable weight ratio. The weight ratio of the crystalline modification II of Becline and the crystalline modification IV of Becmin in the composition may range from about 50: 1 to about 1:50, preferably from about 25: 1 to about 1 : 25, more preferably from about 20: 1 to about 1:20, still more preferably from about 15: 1 to about 1:15, even more preferably from about 10: 1 to about 1:10. A preferred weight ratio for many embodiments is from about 5: 1 to about 1: 5.

The composition of the present invention can be prepared in a conventional manner, for example, by mixing the crystalline modification II of Beccolline with the crystalline modification IV of Bacromin, together with an adjuvant suitable for the form of the formulation. Suitable adjuvants that can be included in the composition according to the invention include all conventional formulated adjuvants or components, such as extenders, carriers, solvents, surfactants, stabilizers, defoamers, antifreeze agents, preservatives Agents, antioxidants, colorants, thickeners, solid binders, and inert fillers. Such auxiliaries are known in the art and are commercially available. Their use in the formulation of the composition of the invention will be apparent to those skilled in the art.

The composition of the invention can be provided in a wide variety of formulation types. Suitable formulations include liquid (SL), emulsion (EC), water emulsion (EW), microemulsion (ME), water suspension (SC), oil-based suspension (OD), seed treatment suspension (FS) , Water-dispersible granules (WG), water-soluble granules (SG), wettable powders (WP), water-soluble powders (SP), granules (GR), capsule granules (CG), fine granules ( FG), large granules (GG), concentrated suspension emulsions (SE), capsule suspensions (CS), and granules (MG). Preferably, the synergistic fungicidal composition is formulated into an aqueous suspension (SC), a water-dispersible granule (WG), a concentrated suspension emulsion (SE), a capsule suspension (CS), and an oil-based suspension. Agents (OD) and water-soluble granules (SG).

The fungicidal composition may include one or more inert fillers. Such inert fillers are known in the art and are commercially available. Suitable fillers include, for example, natural ground minerals such as kaolin, alumina, talc, chalk, quartz, attapulgite, montmorillonite, and diatomaceous earth; or synthetic ground minerals such as highly dispersed silicic acid, alumina , Silicates, and calcium phosphate and dibasic calcium phosphate. Suitable inert fillers for particles include, for example, crushed and classified natural minerals (such as calcite, marble, pumice, sepiolite, and dolomite), or synthetic particles of inorganic and organic abrasive materials, as well as particles of organic materials (such as Sawdust, coconut shell, corn cob, and tobacco stalks).

The fungicidal composition optionally includes one or more surfactants. The one or more surfactants are preferably nonionic, cationic, and / or anionic in nature, and have good emulsification and dispersion. And wetting properties of the surfactant mixture, depending on the nature of the active compound to be formulated. Suitable surfactants are known in the art and are commercially available.

Suitable anionic surfactants can be both so-called water-soluble soaps and water-soluble synthetic surface-active compounds. Soaps that can be used are alkali metal salts, alkaline earth metal salts or substituted or unsubstituted ammonium salts of higher fatty acids (C ₁₀ to C ₂₂ ), such as sodium or potassium salts of oleic acid or stearic acid or a mixture of natural fatty acids.

The surfactant may be an ionic or non-ionic emulsifier, dispersant or wetting agent. Examples that can be used are salts of polyacrylic acid, salts of lignosulfonic acid, salts of benzenesulfonic acid or naphthalenesulfonic acid, polycondensates of ethylene oxide with fatty alcohols or with fatty acids or with fatty amines, substituted phenols (especially Alkylphenols), sulfosuccinate salts, taurine derivatives (especially alkyl taurates) or phosphate esters of polyethoxylated phenols or alcohols. When the active compound and / or inert carrier and / or adjuvant / adjuvant are insoluble in water and the vehicle used for the final application of the composition to plants or plant parts is water, at least one surfactant is generally required. presence.

The fungicidal composition optionally further comprises one or more polymer stabilizers. Suitable polymer stabilizers that can be used in the present invention include, but are not limited to: polypropylene, polyisobutylene, polyisoprene, copolymers of monoolefins and diolefins, polyacrylates, polystyrene, polyvinyl acetate , Polyurethane or Polyamide. Suitable stabilizers are known in the art and are commercially available.

It is generally believed that the above-mentioned surfactants and polymer stabilizers impart stability to the composition, thereby allowing the composition to be formulated, stored, transported, and applied.

Suitable defoamers include all substances which can normally be used for this purpose in agrochemical compositions. Suitable defoamers are known in the art and are commercially available. A particularly preferred defoamer is a mixture of polydimethylsiloxane and perfluoroalkylphosphoric acid, such as silicone defoamers available from GE or Compton.

Suitable organic solvents may be selected from all conventional organic solvents which completely dissolve the active compounds used. In addition, suitable organic solvents for tebuconazole and chlorothalonil are known in the art. The following solvents may be considered to be preferred: N-methylpyrrolidone, N-octylpyrrolidone, cyclohexyl-1-pyrrolidone; or SOLVESSO ^TM 200, paraffin, isoparaffin, A mixture of cycloparaffins and aromatics. Suitable solvents are commercially available.

Suitable preservatives include all substances which can normally be used for this purpose in agrochemical compositions of this type and are also well known in the art. Suitable examples may be mentioned include PREVENTOL ^® (from Bayer AG (Bayer AG)), and PROXEL ^® (from Bayer AG).

Suitable antioxidants are all substances which can normally be used in agrochemical compositions for this purpose, as known in the art. Preferred is butylated toluene.

Suitable thickeners include all substances which can normally be used in agrochemical compositions for this purpose. For example, xanthan gum, polyvinyl alcohol (PVOH), cellulose and its derivatives, hydrated silicate clay, magnesium aluminum silicate, or mixtures thereof. Furthermore, such thickeners are known in the art and are commercially available.

The fungicidal composition may further include one or more solid attachment agents. Such attachment agents are known in the art and are commercially available. They include organic binders, which include tackifiers, such as substituted cellulose, cellulose, natural and synthetic polymers in the form of powders, granules, or latexes, and inorganic binders, such as gypsum, silicon Stone or cement.

Furthermore, depending on the formulation, the composition according to the invention may also contain water.

The formulated composition can be applied, for example, in the form of a spray, for example, using a diluent such as water for appropriate dilution.

The rate of application (use) of components (A) and (B) in the methods and uses of the invention can vary, for example, depending on the type of use, soil type, season, climate, soil ecology and plant type, but allows Both the crystalline modification II of the column and the crystalline modification IV of Becmin are administered in effective amounts to provide the desired effect. The rate of application of components (A) and (B) for a given set of conditions can be easily determined by routine experimentation.

Generally, the application rate of the synergistic fungicidal composition of the present invention is in the range of about 1 to 3 L / ha (liters / ha) or kg / ha (kg / ha).

In the method and use of the present invention, the total application rate of the total amount of the crystalline modification II of component (A) becline and the crystalline modification IV of component (B) becmin is preferably from about 50 to 2000 grams. It is more preferably in the range from about 100 to about 1000 g / ha. In general, when the crystalline modification II of Beccol is from about 25 to about 800 g / ha, preferably from about 20 to about 650 g / ha, and more preferably from about 100 to about 500 g / ha When applied in hectares; and when the crystalline modification IV of bacromin is from about 5 to about 400 g / ha, preferably from about 5 to about 350 g / ha, and more preferably from about 50 to about 300 g / ha When applied on hectares, satisfactory results will be obtained.

The use of such formulations either directly (i.e. undiluted) or after dilution with a suitable solvent (especially water) allows the plants, plant parts and / or their place to be treated and protected from techniques by techniques known in the art Affected by fungal infections. In general, formulations containing such active ingredients can be diluted with water. The composition can be applied by methods known in the art. Such methods include coating, spraying, dipping, pouring, immersing, soaking, injection, rinsing, and the like.

Components (A) and (B) may be applied simultaneously and / or continuously, preferably at short intervals (for example on the same day) to plants, plant parts and / or their locus which are desired to be controlled.

Components (A) and (B) can be applied to the plant, one or more parts of the plant (such as leaves or seeds), or their location in any order. Each component can be applied only once or multiple times. Preferably, each of the components (A) and (B) is applied multiple times, especially from 1 to 6 times.

Components (A) and (B) may be applied in any suitable form as described above. Typically, the active ingredient is administered as a formulation, i.e., a composition comprising one or more active ingredients along with additional carriers, surfactants, or other adjuvants conventionally used in formulation technology to facilitate administration .

In the case where components (A) and (B) are applied simultaneously in the present invention, they can be applied as a composition containing components (A) and (B), in which case components (A) and (B) Can be obtained from separate sources of the formulation and mixed together (known as a tank mix, ready-to-use, spray, or slurry) (optionally with other pesticides), or components (A) and ( B) Can be obtained as a single source of a mixture of formulations (referred to as premixes, concentrates, formulated compounds (or products)), and optionally mixed with other pesticidal agents.

In a preferred embodiment, the method and use of the present invention uses a composition according to the present invention.

The compositions according to the invention differ in the fact that they are particularly well tolerated by the treated plants and are environmentally friendly.

For illustrative purposes, specific embodiments of the invention are described by the following examples.

In these examples, percentages are by weight unless otherwise stated.

Examples

Formulation examples

    Example 1-Baclipline Crystal Modification II Suspension (SC)    

Aqueous suspensions (SC) containing crystalline modification II of Beckley were prepared from the components listed in the table below.

    Example 2-Aqueous suspension (SC) of Bacromin IV    

Suspensions (SC) containing crystalline modification IV of Bacromin were prepared from the components listed in the table below.

    Example 3-Aqueous suspension (SC) of baicale crystalline modification I + Becmin crystal modification I    

From the components listed in the following table, an aqueous suspension (SC) containing Beccollite crystalline modification I and Becquermin crystalline modification I was prepared.

    Example 4-Suspending Agent (SC)    

Suspensions (SC) containing Bacridol Crystal Modification I and Becmin Crystal Modification II were prepared from the components listed in the table below.

    Example 5-Suspending Agent (SC)    

Suspensions (SC) containing Bacridol Crystal Modification I and Becmin Crystal Modification III were prepared from the components listed in the table below.

    Example 6-Suspending Agent (SC)    

Suspensions (SC) were prepared from the components listed in the table below, including Bacridol crystalline modification I and Becmin crystal modification IV.

    Example 7- Aqueous suspension (SC) of Bectiql Crystal Modification II + Becmin Crystal Modification I    

Suspensions (SC) containing Bectiql Crystal Modification II and Becmin Crystallization Modification I were prepared from the components listed in the table below.

    Example 8-Aqueous suspension (SC) of Becline crystal modification II + Becmin crystal modification II    

An aqueous suspension (SC) was prepared from the components listed in the table below, including Bexcolide crystalline modification II and Pakmin crystal modification II.

    Example 9-Aqueous suspension (SC) of Bectiql Crystal Modification II + Becmin Crystallization Modification III    

An aqueous suspension (SC) was prepared from the components listed in the table below, including becline crystal modification II and becmin crystal modification III.

    Example 10-Aqueous Suspension (SC) of Becline Crystal Modification II + Becmin Crystal Variation IV    

Suspensions (SC) were prepared from the components listed in the table below, including Bexcolide crystal modification II and Becmin crystal modification IV.

    Example 11-Aqueous suspension (SC) of Becline crystal modification II + Becmin crystal modification IV    

Suspensions (SC) were prepared from the components listed in the table below, including Bexcolide crystal modification II and Becmin crystal modification IV.

    Example 12-Water-dispersible granules of Becline crystal modification II + Becmin crystal modification IV    

A water-dispersible granule (WG) composition comprising Baklie crystal modification II and Becmin crystal modification IV was prepared from the components listed in the following table.

    Example 13-Microencapsulated Suspension (CS) of Becline Crystal Modification II + Becmin Crystal Variation IV    

Capsule suspensions (CS) containing Bacridol crystalline modification II and Becmin crystal modification IV were prepared from the components listed in the table below.

    Example 14-Water-dispersible granules of Becline crystal modification II + Becmin crystal modification IV    

A water-dispersible granule (WG) composition comprising Baklie crystal modification II and Becmin crystal modification IV was prepared from the components listed in the following table.

    Example 15- Water-soluble granules (SG) of Becline crystal modification II + Becmin crystal modification IV    

A water-soluble granule (SG) composition comprising Baklie crystal modification II and Becmin crystal modification IV was prepared from the components listed in the following table.

    Example 16-Seed treatment suspending agent (FS)    

A seed treatment suspending agent (FS) was prepared from the components listed in the table below, including Bacridol Crystal Variation II and Pakmin Crystal Variation IV.

    Example 17-Concentrated Suspension Emulsion (SE) of Becline Crystal Variation II + Becmin Crystal Variation IV    

A concentrated suspoemulsion (SE) composition was prepared from the components listed in the following table, comprising the Beckley crystal modification II and the becmin crystal modification IV.

    Example 18-An oil-based suspending agent (OD) of Becline crystal modification II + Becmin crystal modification IV    

An oil-based suspending agent (OD) composition was prepared from the components listed in the following table, comprising Bacridol crystalline modification II and Becmin crystal modification IV.

    Example 19-Water-dispersible Granules (WG)    

A water-dispersible granule (WG) composition containing crystalline modification II of Beckley was prepared from the components listed in the table below.

    Example 20-Aqueous Suspension (SC)    

An aqueous suspension (SC) composition containing crystalline modification IV of Bacromin was prepared from the components listed in the table below.

Biological examples

When the activity of a composition containing two active compounds is greater than the sum of the activities of the two active compounds administered alone, the combination of the two active compounds appears to be synergistic. The expected activity of a given combination of two active compounds can be calculated by the so-called "Colby formula" (see SR Colby, "Calculating Synergistic and Antagonistic Responses of Herbicide Combinations (Calculating Synergistic and Antagonistic Responses of Herbicide Combinations ", Weeds 1967, 15, 20-22): where: A = activity of compound A when active compound A is used at an application rate of mg / ha (g / ha) Percentage; B = Percent activity of compound B when active compound B is used at an application rate of ng / ha (g / ha); E = When mg / ha (g / ha) and ng / ha (g / ha) When compounds A and B are used together, the percentage of activity is estimated; then: E = A + B- (A × B / 100).

If the actual activity observed for the combination of compounds A and B is greater than the calculated activity, the activity of the combination is superadditive. In other words, synergy exists.

In the following examples, the severity of fungal infections is expressed as the percentage of plants infected with the indicated fungi.

Biological Example 1-Grape (Vitis vinifera)

Grape plants were sprayed with a conidia suspension of the genus P. viticola and cultivated for 48 hours at 20 ° C and 100% relative atmospheric humidity. The plants were then sprayed with the composition of Formulation Examples 1 to 20 described above. The treated plants were kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are summarized in the table below.

From the data listed in the table above, it can be seen that the combination of Becline and Becmin (especially the combination of Becline's crystalline variant II and Becmin's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 2-Grape (Grape Powdery Mildew)

Grape plants were sprayed with a conidial suspension of the powdery mildew of Grapevine, and incubated for 48 hours at 20 ° C and 100% relative atmospheric humidity. The plants were then sprayed with the composition of Formulation Examples 1 to 20 described above. The treated plants were kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 3-Grape (Botrytis cinerea)

Grape plants were sprayed with a conidial suspension of Botrytis cinerea and cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition of Formulation Examples 1 to 20 described above. After treatment, the plants were kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated. The results are summarized in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 4-Barley

Barley plants were sprayed with a conidia suspension of Helminthosporium sclerotiorum / C. Sclerotiorum and cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition of Formulation Examples 1 to 20 described above. After treatment, the plants were kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days. The severity of the fungal infection was then assessed.

The results are summarized in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 5-Barley (Barley Moire)

Barley plants were sprayed with a conidial suspension of barley moirella and cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition of Formulation Examples 1 to 20 described above. The treated plants were kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are summarized in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 6-Barley

The barley plants were sprayed with a conidial suspension of Phytophthora spp. And cultivated for 48 hours at 20 ° C and 100% relative atmospheric humidity. The plants were then sprayed with the composition of Formulation Examples 1 to 20 described above. The treated plants were kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are summarized in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 7-Wheat (wheat leaf rust)

Wheat plants were sprayed with a conidial suspension of wheat rust fungus and cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition according to Formulation Examples 1 to 20 above. The treated plants were then kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 8-Wheat (H. tritici)

Wheat plants were sprayed with conidia suspensions of Trichosporum spp. And cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition according to Formulation Examples 1 to 20 above. The treated plants were then kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 9-Wheat

Wheat plants were sprayed with conidia suspensions of Trichosporum spp. And cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition according to Formulation Examples 1 to 20 above. The treated plants were then kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 10-Wheat (Puccinia striiformis)

Wheat plants were sprayed with a conidial suspension of Puccinia striiformis and cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition according to Formulation Examples 1 to 20 above. The treated plants were then kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 11-Banana (Banana leaf spot disease)

Banana plants were sprayed with a conidial suspension of Banana Leaf Spot Bacteria and cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition according to Formulation Examples 1 to 20 above. The treated plants were then kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 12-Soybean

Soybean plants were sprayed with a conidial suspension of Puccinia striiformis and cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition according to Formulation Examples 1 to 20 above. The treated plants were then kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 13-Brassica napus

The rapeseed plant was sprayed with a conidia suspension of Micrococcus crassiaceae and cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition according to Formulation Examples 1 to 20 above. The treated plants were then kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 14-Rapeseed (Brassica brassicae)

Rapeseed plants were sprayed with a conidial suspension of Brassica leaf spot and cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition according to Formulation Examples 1 to 20 above. The treated plants were then kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 15-Rape (Sclerotinia sclerotiorum)

The rapeseed plants were sprayed with a conidia suspension of Sclerotinia sclerotiorum and cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition according to Formulation Examples 1 to 20 above. The treated plants were then kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 16-Apple (White Fork Shell)

Apple plants were sprayed with a conidia suspension of the white-fork silk single-capsule shell and cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition according to Formulation Examples 1 to 20 above. The treated plants were then kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 17-Peach (Monascus rosea)

Peach plants were sprayed with conidia suspensions of R. monochaeae and cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition according to Formulation Examples 1 to 20 above. The treated plants were then kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 18-Pear (Black Star Disease)

Pear plants were sprayed with a conidial suspension of Nigella niger and cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition according to Formulation Examples 1 to 20 above. The treated plants were then kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological example 19-Brassica

Cabbage plants were sprayed with a conidial suspension of a uniaxial Mycobacterium spp. And cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition according to Formulation Examples 1 to 20 above. The treated plants were then kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 20-Tomato (Mesporia)

Tomato plants were sprayed with conidia suspensions of the genus Sporocystis and cultivated at 20 ° C and 100% relative atmospheric humidity for 48 hours. The plants were then sprayed with the composition according to Formulation Examples 1 to 20 above. The treated plants were then kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Biological Example 21-Cucumber (Botrytis cinerea)

Cucumber plants were sprayed with a conidial suspension of Botrytis cinerea and grown for 48 hours at 20 ° C and 100% relative atmospheric humidity. The plants were then sprayed with the composition according to Formulation Examples 1 to 20 above. The treated plants were then kept in a greenhouse at 15 ° C and 80% relative atmospheric humidity for 10 days, after which the severity of the fungal infection was evaluated.

The results are listed in the table below.

From the data listed in the table above, it can be seen that the combination of Beckley and Becmin (specifically the combination of Beckley's crystalline variant II and Beckley's crystalline variant IV) has shown significant control of fungal infections Increased activity. The results showed synergy.

Claims (57)

    A fungicidal composition comprising: (A) 2-chloro-N- (4'chloro [1,1'biphenyl] -2-yl) 3-pyridamidine (boscalid) Crystalline modification II; and (B) N- {2- [1- (4-chlorophenyl) -1H-pyrazol-3-yloxymethyl] phenyl} (N-methoxy) amine Crystalline modification IV of methyl carbamate (pyraclostrobin).         The composition according to item 1 of the scope of the patent application, wherein the crystalline modification II of Becqueride is present in the synergistic fungicidal composition in an amount from about 1% to about 80% by weight of the composition .         The composition according to item 2 of the scope of the patent application, wherein the crystalline modification II of Beccolide is present in the synergistic fungicidal composition in an amount of from about 1% to 70% by weight.         The composition according to item 3 of the scope of the patent application, wherein the crystalline modification II of Beccolide is present in the synergistic fungicidal composition in an amount of from about 1% to 60% by weight.         The composition according to any one of the foregoing patent claims, wherein the crystalline modification IV of Bacromin is present in the synergistic fungicidal composition in an amount from about 1% to 70% by weight.         The composition according to item 5 of the scope of patent application, wherein the crystalline modification IV of Bacromin is present in the synergistic fungicidal composition in an amount of from about 1% to 60% by weight.         The composition according to item 6 of the scope of patent application, wherein the crystalline modification IV of Bacromin is present in the synergistic fungicidal composition in an amount of from about 1% to 50% by weight.         The composition according to any one of the foregoing patent claims, wherein the weight ratio of the crystalline modification II of Becline and the crystalline modification IV of Becmin in the composition is from about 50: 1 to about The range is 1:50.         The composition according to item 8 of the scope of application for a patent, wherein the weight ratio of the crystalline modification II of Becline and the crystalline modification IV of Becmin in the composition is from about 25: 1 to about 1: Within 25.         The composition according to item 9 of the scope of application for a patent, wherein the weight ratio of the crystalline modification II of Becline and the crystalline modification IV of Becmin in the composition is from about 20: 1 to about 1: Within the range of 20.         The composition according to item 10 of the scope of application for a patent, wherein the weight ratio of the crystalline modification II of Becline and the crystalline modification IV of Becmin in the composition is from about 15: 1 to about 1: 15 range.         The composition according to item 11 of the scope of application for a patent, wherein the weight ratio of the crystalline modification II of Becline and the crystalline modification IV of Becmin in the composition is from about 10: 1 to about 1: Within the range of 10.         The composition according to item 12 of the scope of application for a patent, wherein the weight ratio of the crystalline modification II of Becline and the crystalline modification IV of Becmin in the composition is from about 5: 1 to about 1: Range of 5.         The composition according to any one of the foregoing patent claims, wherein the composition includes one or more auxiliary agents selected from the group consisting of: extenders, carriers, solvents, surfactants, stabilizers, defoamers, Antifreezes, preservatives, antioxidants, colorants, thickeners, solid binders, and inert fillers.         The composition according to any one of the aforementioned patent applications, wherein the composition is a liquid (SL), an emulsion (EC), an aqueous emulsion (EW), a microemulsion (ME), an aqueous suspension (SC), Oil-based suspension (OD), seed treatment suspension (FS), water-dispersible granules (WG), water-soluble granules (SG), wettable powder (WP), water-soluble powder (SP), granules (GR), capsule granules (CG), fine granules (FG), large granules (GG), concentrated suspension emulsion (SE), capsule suspension (CS) or granules (MG).         The composition according to item 15 of the scope of patent application, wherein the composition is a water suspension (SC), a water-dispersible granule (WG), a thick suspension emulsion (SE), a capsule suspension (CS), an oil Base suspension (OD) or water-soluble granules (SG).         A method for preventing and / or treating fungal infections in plants and / or plant parts, the method comprising applying to the plants and / or plant parts: (A) 2-chloro-N- (4'chloro [1,1 'Biphenyl] -2-yl) crystalline modification II of 3-pyridamidine (Beckley); and (B) N- {2- [1- (4-chlorophenyl) -1H-pyridine A crystalline modification IV of azole-3-yloxymethyl] phenyl} (N-methoxy) aminoformic acid methyl ester (Hexamine).         The method according to item 17 of the scope of patent application, wherein the treated plants are selected from the group consisting of cereals, fruits, berries, leguminous plants, oil plants, cucurbitaceae, citrus fruits, vegetables, ornamental plants, broadleaf trees and evergreens .         The method of claim 18, wherein the plants to be treated are selected from wheat, barley, rye, oats, corn, rice, sorghum and triticale; apples, pears, plums, peaches, pistachios, Batam, cherries, grapes, bananas, strawberries, shrub berries, cranberries, raspberries and blackberries; beans, lentils, peas and soybeans; canola, mustard and sunflower; cantaloupe, zucchini, cucumber, melon, pumpkin, Squash and watermelon; orange, lemon, grapefruit and citrus; spinach, lettuce, asparagus, cabbage, carrot, onion, tomato, potato, red pepper, garlic and shallot; coffee; sugar cane; hops; nuts; roses, Shrubs and cypresses.         The method of claim 19, wherein the plants to be treated are selected from wheat, barley, oats, rice, grapes, bananas, soybeans, rapeseed and vegetables.         The method according to any one of claims 17 to 20, wherein the weight ratio of the crystalline modification II of Beccolline and the crystalline modification IV of Becmin is from about 50: 1 to about 1:50 In the range.         The method as described in claim 21, wherein the weight ratio of the crystalline modification II of Becline and the crystalline modification IV of Becmin is in the range from about 25: 1 to about 1:25.         The method as described in claim 22, wherein the weight ratio of the crystalline modification II of Beccolline and the crystalline modification IV of Becmin is in a range from about 20: 1 to about 1:20.         The method as described in claim 23, wherein the weight ratio of the crystalline modification II of Beccolline and the crystalline modification IV of Becmin is in a range from about 15: 1 to about 1:15.         The method as described in claim 24, wherein the weight ratio of the crystalline modification II of Beccolline and the crystalline modification IV of Becmin is in a range from about 10: 1 to about 1:10.         The method as described in claim 25, wherein the weight ratio of the crystalline modification II of Beccolle and the crystalline modification IV of Becmin is in a range from about 5: 1 to about 1: 5.         The method according to any one of claims 17 to 26 of the scope of application, wherein the total amount of the crystalline modification II of component (A) Becline and the crystalline modification IV of component (B) The rate is in the range from about 100 to about 1000 g / ha.         The method according to any one of claims 17 to 27 of the scope of the patent application, wherein the application rate of the crystalline variant II of component (A) Becline is in the range from about 25 to about 800 g / ha.         The method as described in claim 28, wherein the application rate of the crystalline modification II of Beckley is in the range from about 20 to about 650 g / ha.         The method as described in claim 29, wherein the application rate of the crystalline modification II of Baker's column is in the range from about 100 to about 500 g / ha.         The method according to any one of claims 17 to 30 of the scope of the patent application, wherein the application rate of the crystalline variant IV of the component (B) bacromin is in the range from about 5 to about 400 g / ha.         The method as described in claim 31, wherein the application rate of the crystalline variant IV of Bacromin is in a range from about 5 to about 350 g / ha.         The method according to item 32 of the scope of application, wherein the application rate of crystalline variant IV of Bacromin is in a range from about 50 to about 300 g / ha.         The method according to any one of claims 17 to 33 of the scope of patent application, wherein the components (A) and (B) are applied simultaneously and / or sequentially to the plants, plant parts and / or loci that are desired to be controlled.         The method according to any one of claims 17 to 34, wherein the composition described in any one of claims 1 to 16 is used.         Use of a component for the prevention and / or treatment of fungal infections in plants and / or plant parts: (A) 2-chloro-N- (4'chloro [1,1'biphenyl] -2-yl) Crystalline modification II of 3-pyridinecarboxamide (Beckley); and (B) N- {2- [1- (4-chlorophenyl) -1H-pyrazol-3-yloxymethyl] Crystalline modification IV of phenyl} (N-methoxy) carbamate (Hexamin).         The use as described in claim 36, wherein the plants to be treated are selected from the group consisting of cereals, fruits, berries, leguminous plants, oil plants, cucurbitaceae, citrus fruits, vegetables, ornamentals, broadleaf trees and evergreens .         The use as described in claim 37, wherein the plants to be treated are selected from wheat, barley, rye, oats, corn, rice, sorghum and triticale; apples, pears, plums, peaches, pistachios, Batam, cherries, grapes, bananas, strawberries, shrub berries, cranberries, raspberries and blackberries; beans, lentils, peas and soybeans; canola, mustard and sunflower; cantaloupe, zucchini, cucumber, cantaloupe, squash, pumpkin Watermelon; orange, lemon, grapefruit and citrus; spinach, lettuce, asparagus, cabbage, carrot, onion, tomato, potato, red pepper, garlic and shallot; coffee; sugar cane; hops; nuts; roses, shrubs and cypress.         The use as described in claim 38, wherein the plants to be treated are selected from wheat, barley, oats, rice, grapes, bananas, soybeans, rapeseed and vegetables.         The use as described in any one of claims 36 to 39, wherein the weight ratio of the crystalline modification II of Becline and the crystalline modification IV of Becmin is from about 50: 1 to about 1:50 In the range.         The use as described in item 40 of the scope of patent application, wherein the weight ratio of the crystalline modification II of Beccolline and the crystalline modification IV of Becmin is in a range from about 25: 1 to about 1:25.         The use as described in item 41 of the scope of patent application, wherein the weight ratio of the crystalline modification II of Beccolline and the crystalline modification IV of Becmin is in a range from about 20: 1 to about 1:20.         The use as described in claim 42 of the application, wherein the weight ratio of the crystalline modification II of Beccolline and the crystalline modification IV of Becmin is in the range from about 15: 1 to about 1:15.         The use as described in claim 43 of the scope of patent application, wherein the weight ratio of the crystalline modification II of Beccolline and the crystalline modification IV of Becmin is in a range from about 10: 1 to about 1:10.         The use as described in claim 44 of the scope of patent application, wherein the weight ratio of the crystalline modification II of Beccolline and the crystalline modification IV of Becmin is in a range from about 5: 1 to about 1: 5.         The use as described in any one of claims 36 to 45 of the scope of application, wherein the total amount of the crystalline variant II of component (A) Becline and the crystalline modification IV of component (B) The rate is in the range from about 100 to about 1000 g / ha.         The use according to any one of claims 36 to 46 of the scope of the patent application, wherein the application rate of the crystalline variant II of component (A) Becline is in the range from about 25 to about 800 g / ha.         The use as described in claim 47 of the scope of patent application, wherein the application rate of the crystalline modification II of Baker's column is in the range from about 20 to about 650 g / ha.         The use as described in claim 48 of the scope of application, wherein the application rate of the crystalline variant II of Baker's column is in the range from about 100 to about 500 g / ha.         The use according to any one of claims 36 to 49 of the scope of application, wherein the application rate of the crystalline variant VI of the component (B) bacromin is in the range from about 5 to about 400 g / ha.         The use as described in claim 50 of the scope of application, wherein the application rate of crystalline variant IV of Bacromin is in the range from about 5 to about 350 g / ha.         The use as described in claim 51 of the scope of patent application, wherein the application rate of crystalline variant IV of Bacromin is in the range from about 50 to about 300 g / ha.         The use as described in any one of claims 36 to 52, wherein the components (A) and (B) are applied simultaneously and / or sequentially to the plant, plant part and / or place where it is desired to control .         The use according to any one of claims 36 to 53 in the scope of patent application, wherein the composition described in any one of claims 1 to 16 is used.         A fungicidal composition substantially as described above.         A method for treating and / or preventing fungal infections in plants and / or plant material substantially as described above.         A use substantially as described above.