TWI714636B - A synergistic insecticidal composition - Google Patents

Abstract

The present invention provides a synergistic insecticidal composition comprising three components(A) buprofezin, (B) thiamethoxam and (C) lambda-cyhalothrin. There is also provided a process for preparing the insecticidal composition. The present invention is also related to a method to prevent, control and/or treat insect infestations in plants, plant parts and/or their surroundings by applying the synergistic insecticidal composition comprising three components (A) buprofezin, (B) thiamethoxam and (C) lambda-cyhalothrin.

Description

Synergistic insecticidal composition

The present invention relates to a synergistic insecticidal composition, which contains three active components. The present invention also relates to a method for preparing the insecticidal composition, and to a method for preventing, controlling and/or treating insect infestation in plants, plant parts and/or their surrounding environment by applying the synergistic insecticidal composition Method of dyeing.

Insect infestation represents a major threat to important economic crops. The yield of plants (for example, fruits, legumes, Cucurbitaceae, fiber plants, citrus, vegetables, sugarcane) is adversely affected by insect attack.

Chemical control is an important way to prevent and control agricultural pests. However, current reagents cannot show satisfactory effects on certain kinds of harmful organisms. In addition, due to the long-term use of pesticides, many harmful organisms have developed resistance to commonly used pesticides. Therefore, there is an urgent need to develop new methods and pesticides and/or compositions containing them for controlling these harmful organisms. In addition, the environmental and economic requirements imposed on today's insecticides are constantly increasing with regard to, for example, the range of action, toxicity, selectivity, application rate, formation of residues, and favorable manufacturing capabilities. Due to possible problems (e.g., resistance to known active compounds), an unchanging task is to develop new insecticides that are superior to their known counterparts in at least some aspects.

Thiamethoxam is 3-[(2-chloro-5-thiazolyl)methyl]tetrahydro-5-methyl-N-nitro-4H-1,3,5-oxadiazine-4- The common name of imine and has the following chemical formula I:

Saisuan is known to have insecticidal activity and is commercially available.

However, experience based on single-active direct formulations of insecticides worldwide shows that the risk of development of resistant insect subpopulations is very high. It has been reported worldwide that insects, which are active in field crops, fruits, vegetables, etc., are increasingly resistant to pesticides.

Pyrethroids are known insecticides and are synthetic derivatives of naturally occurring pyrethrins (which are taken from pyrethrum, the oleoresin extract of dried chrysanthemum). The ketol esters of chrysanthemum acid and pyrethrum acid lead to the insecticidal properties of pyrethrin. These acids are lipophilic and penetrate insects and paralyze their nervous systems (Reigart, et al., 1999). It is well known that the insecticidal effect of pyrethroids can effectively resist a variety of insect pests in many major crops (such as fruits, vegetables, grains, corn, cotton, soybeans, grapes), and even in the field of public health and animal health effective. The activity of pyrethroids is both contact action and gastric action, as a broad-spectrum insecticide. Examples of synthetic pyrethroids are deltamethrin, lambda-cyhalothrin, fenvalerate, permethrin, cypermethrin, bifenthrin , Esfenvalerate, etofenprox, cyfluthrin, fenpropathrin, allethrin, cyphenothrin, flucythrinate, flucythrin Permethrin (flumethrin), imimiprothrin (imiprothrin), metofluthrin (metofluthrin), dexpropargyl (prallethrin), resmethrin (resmethrin), silafluofen ), sumithrin, tefluthrin, tetramethrin, tralomethrin and transluthrin.

Buprofezin is a well-known and easily available pesticide, and methods for producing it are known in the art, for example, see U.S. Patent 4,159,328. It is a possible chitin synthesis and prostaglandin inhibitor. It inhibits the molting of nymphs and larvae, which eventually leads to their death.

The enhancement of pesticides and compositions has been achieved to improve the control of insect pests and the application of pesticides to target crops as single or mixed pesticides. Use strip application or spot application and soil application to avoid direct contact with natural enemies only for areas with high insect incidence, and the use of selective agents and non-persistent agents The use increases environmental safety and reduces the incidence of insect resistance. In addition, rotational application of insect control agents with different mechanisms of action contributes to good pest management. What is desirable is an insecticidal composition with high synergistic effect, no cross-resistance to existing insecticides, and low environmental impact. Therefore, it would be advantageous to provide a composition that is effective against insect attack, has a physically compatible formulation that is stable during storage, safe packaging, and in a ready-to-use formulation.

The present invention provides a synergistic insecticidal composition, which comprises three components: (A) ibufungin, (B) ceroxan and (C) ceronin.

The present invention also provides a method for controlling insect infestation in plants, plant parts and/or their surrounding environment by applying a synergistic insecticidal composition comprising the above-mentioned components (A), (B) and (C) For plants, plant parts and/or surrounding environment.

The present invention also provides a method for preparing a synergistic insecticidal composition, the synergistic insecticidal composition comprising three components: (A) ibufungin, (B) acesulfan and (C) xeronin.

The present invention also provides an association comprising the above components (A), (B) and (C) The same-sex insecticidal composition is used to prevent, control and/or treat plants, plant parts and/or the use of insect infestation in the surrounding environment.

"Plant" as used herein refers to all plants and plant groups, such as desired and undesired wild plants or crop plants.

"Plant parts" as used herein refer to all parts and organs of plants, such as buds, leaves, needles, stems, stems, fruiting bodies, fruits, seeds, roots, tubers, and rhizomes. It also includes harvested material, as well as vegetative and reproductive propagation material, such as cuttings, tubers, meristems, rhizomes, short stolons, seeds, single and multiple plant cells and any other plant tissues.

The term "environment" refers to the place where the plant grows, the place where the plant propagation material of the plant is sown, or the place where the plant propagation material of the plant will be sown.

"At least one" means 1, 2, 3, 4, 5, 6, 7, 8, 9, or more of the corresponding compounds, preferably 1, 2, or 3.

If not stated otherwise, the term "%" usually means weight-%.

It has now been unexpectedly discovered that when an insecticidal composition containing three components (namely (A) Bufungin, (B) Celonine, and (C) Celonine) is applied to plants, plant parts and/or In its surrounding environment (for example, soybeans, dry beans, cotton, vegetables, fruits, citrus, and sugar cane), excellent performance in preventing, controlling and treating insect infestation can be observed. The synergistic insecticidal composition highly effectively protects the aforementioned crops from insect attack.

It was found that the synergistic insecticidal composition is highly active against a wide range of pests, such as aphids, marching insects, beetles, cotton bollworms, heart worms, pickle insects, burrowing bugs, borers, caterpillars ), citrus orthezia, Great Southern White, leafhoppers, leaf miners, loopers, millipedes, side polyphagous mites, moths, spider mites, foam cicadas, stink bugs, termites, Thrips, elephant heads, whiteflies, worms, psyllids. The composition of the present invention is particularly effective against aphids, beetles, cotton bollworms, Drill borers, leafhoppers, moths, foam cicadas, stink bugs, termites, thrips, elephant heads, whiteflies, psyllids.

The invention also demonstrates reduced application costs, increased crop yields, and reduced environmental hazards. It also basically prevents the development of resistant strains of pests and/or delays the advantages of resistant strains of pests, has a wider spectrum of activity and reduces the risk of developing resistance.

The present invention also provides a method of using a synergistic insecticidal composition for crop protection. The synergistic insecticidal composition comprises three components: ibufungin, celoxan and xeronin. When coating and/or containing the synergistic composition of the present invention, the advantages of this method relate to the propagation of plant parts and especially seeds.

In the use of the present invention, components (A), (B) and (C) can be applied to plants or plant materials in any desired order, in any combination, continuously or simultaneously.

Component (A) Bufungin may be present in the composition of the present invention in any suitable amount, and is generally present in an amount from about 1% to about 75% by weight of the composition, preferably It is present in an amount from about 1% to about 60%, from about 1% to about 50% by weight of the composition, and more preferably from about 5% to about 45% by weight of the composition Is present in an amount, even more preferably present in an amount from about 5% to about 45% by weight, even more preferably present in an amount from about 10% to about 45% by weight, most preferably It is present in an amount of 20% to about 40%, or in an amount of about 20%, 25%, 30%, or 40%.

Component (B) acesulfan may be present in the composition in any suitable amount, and is usually present in an amount from about 0.1% to about 50% by weight of the composition, preferably in the amount The weight of the composition is present in an amount of from about 0.1% to about 40%, from about 0.1% to about 30%, from about 1% to about 30%, more preferably from about 1% to about 20%, even more preferably from about 1% to about 15% by weight of the composition, even more preferably from about 1% to about 15% by weight of the composition Is present in an amount of 4% to about 15%, and optimally It is present in an amount of 4.5%, 6.5%, 9% or 15%.

Component (C) Xeronine may be present in the composition in any suitable amount, and is usually present in an amount from about 0.1% to about 50% by weight of the composition, preferably in the amount The weight of the composition is present in an amount of from about 0.1% to about 40%, from about 0.1% to about 30%, from about 1% to about 30%, more preferably from about 1% to about 20%, even more preferably from about 1% to about 15% by weight of the composition, even more preferably from about 1% to about 15% by weight of the composition It is present in an amount of 2% to about 15%, and optimally in an amount of 2.5%, 5%, 7.5%, or 15%.

These components (A), (B) and (C) may be present in the composition or applied in any amount relative to each other to provide a synergistic effect of the mixture. Specifically, the weight ratio of component (A) to component (B) in the composition is independently preferably from about 99:1 to about 1:99, about 50:1 to about 1:50, about In the range of 25:1 to about 1:25, more preferably in the range of from about 15:1 to about 1:1 or about 12:1 to about 1:1 or about 8:1 to about 1:1. Preferably, the weight ratio of component (A) to component (B) in the composition is about 2:1, 3:1 or 5:1. Specifically, the weight ratio of component (A) to component (C) in the composition is independently preferably from about 99:1 to about 1:99, about 50:1 to about 1:50, about In the range of 25:1 to about 1:25, more preferably in the range of from about 15:1 to about 1:1 or about 12:1 to about 1:1 or about 8:1 to about 1:1. Preferably, the weight ratio of component (A) to component (C) in the composition is about 4:1, 5:1, 6:1.

These components (A), (B) and (C) can be present together in the composition in any suitable amount, and are usually from about 5% to about 90% of the total amount by weight of the composition Exist, preferably present in a total amount from about 10% to about 80% by weight of the composition, more preferably from about 15% to about 70% by weight of the composition exist.

Preferably, each combination is a composition comprising components (A), (B) and (C), and optionally one or more auxiliary agents. The additives used in the composition will It depends on the type of formulation and/or the way the end user will apply the formulation. Various formulations incorporated into the composition of the present invention are described below. Suitable adjuvants that can be included in the composition according to the present invention are all conventional formulation adjuvants or components, such as extenders, carriers, solvents, surfactants, stabilizers, defoamers, antifreezes, Preservatives, antioxidants, colorants, thickeners, solid adhesives and inert fillers. Such adjuvants are known in the art and are commercially available. Their use in the formulation of the composition of the present invention is clear to those skilled in the art.

The composition may further comprise one or more inert fillers. Such inert fillers are known in the art and are commercially available. Suitable fillers in solid form include, for example, natural ground minerals (such as kaolin, alumina, talc, chalk, quartz, attapulgite, montmorillonite, and diatomaceous earth) or synthetic ground minerals (such as highly dispersed silica Acid, alumina, silicate, and calcium phosphate and dibasic calcium phosphate). Suitable inert fillers for granules include, for example, crushed and classified natural minerals (such as calcite, marble, pumice, sepiolite, and dolomite), or synthetic particles of inorganic and organic abrasive materials, and particles of organic materials ( Such as sawdust, coconut husk, corn cob, and tobacco stem).

The composition may optionally include one or more surfactants, which are preferably nonionic, cationic and/or anionic in nature, as well as surfactants with good emulsifying, dispersing and wetting properties The mixture depends on the nature of the active compound to be formulated. Suitable surfactants are known in the art and are commercially available. Suitable anionic surfactants can be both so-called water-soluble soaps and water-soluble synthetic surface-active compounds. The soaps that can be used are alkali metal salts, alkaline earth metal salts or substituted or unsubstituted ammonium salts of higher fatty acids (C ₁₀ -C ₂₂ ), for example, sodium or potassium oleic acid or stearic acid , Or sodium or potassium salt of natural fatty acid mixture. The surfactant can be an ionic or non-ionic emulsifier, dispersant or wetting agent. Examples that can be used are the salt of polyacrylic acid, the salt of lignosulfonic acid, the salt of benzenesulfonic acid or naphthalenesulfonic acid, the polycondensate of fatty alcohol or fatty acid or fatty amine of ethylene oxide, substituted phenol Phenol), sulfosuccinates, taurine derivatives (especially alkyl taurates), or polyethoxylated phenol or alcohol phosphate esters. When the active compound and/or inert carrier and/or adjuvant/adjuvant are not soluble in water and the vehicle for the final application of the composition is water, the presence of at least one surfactant is usually required.

The composition may optionally further comprise one or more polymer stabilizers. Suitable polymer stabilizers that can be used in the present invention include, but are not limited to: polypropylene, polyisobutylene, polyisoprene, copolymers of monoolefins and dienes, polyacrylates, polystyrene, polyvinyl acetate, Polyurethane or polyamide. Suitable stabilizers are known in the art and are commercially available.

It is generally believed that the aforementioned surfactants and polymer stabilizers impart stability to the composition, thereby allowing the composition to be formulated, stored, transported, and applied.

Suitable defoamers include all substances that can normally be used in agrochemical compositions for this purpose. Suitable defoamers are known in the art and are commercially available. A particularly preferred defoamer is a mixture of polydimethylsiloxane and perfluoroalkyl phosphoric acid, such as the silicone defoamer available from GE or Compton.

Suitable organic solvents are selected from all conventional organic solvents, which completely dissolve the active compound used. Again, suitable organic solvents for the active components (A), (B) and (C) are known in the art. The following may be mentioned as preferred ones: N-methylpyrrolidone, n-octylpyrrolidone, cyclohexyl-1-pyrrolidone; or SOLVESSO ^™ 200, a mixture of paraffin, isoparaffin, cycloalkane and aromatic hydrocarbon. Suitable solvents are commercially available.

Suitable preservatives include all substances that can normally be used in this type of agrochemical composition for this purpose and are also well known in the art. Suitable examples may be mentioned include PREVENTOL ^® (from Bayer AG (Bayer AG)), and PROXEL ^® (from Bayer AG).

Suitable antioxidants are all substances that can normally be used in agrochemical compositions for this purpose, as known in the art. Preferred is dibutylhydroxytoluene.

Suitable thickeners include all substances that can normally be used in agrochemical compositions for this purpose. For example, xanthan gum, PVOH, cellulose and its derivatives, hydrated silicate clay, magnesium aluminum silicate or their mixtures. Again, such thickeners are known in the art and are commercially available.

The composition may further comprise one or more solid adhesives. Such adhesives are known in the art and are commercially available. They include organic binders, including tackifiers such as substituted cellulose cellulose, natural and synthetic polymers in powder, granular, or lattice form, and inorganic binders such as gypsum, silica or cement.

Furthermore, depending on the formulation, the composition according to the invention may also comprise water.

The composition of the present invention can be used in the agricultural industry and related application fields for the prevention and control of insects, such as but not limited to: aphids, marching insects, beetles, cotton bollworms, heartworms, pickle insects, burrowing bugs , Borer, caterpillar, citrus orthezia, Great Southern White, leafhopper, leaf miner, looper, millipede, polyphagous mites, moths, spider mites, Cicadas, stink bugs, termites, thrips, elephant heads, whiteflies, worms, psyllids; preferably aphids, beetles, cotton bollworms, borers, leafhoppers, moths, foam cicadas, stink bugs, termites, thrips , Elephant cape, whitefly, psyllids; more preferably Agriotes spp., Alabama spp., Anthonomus spp., dry worm Anticarsia spp.), Aphis spp., Aracanthus, Bemicia, Brevicoryne spp., Caliothrips spp., Capitophorus spp., Diabrotica spp., Diaphorina spp., Dilobopterus, Ecdytolopha, Jade Rice stem borer (Elasmopalpus spp.), Empoasca spp., Enneothrips, Eriosoma spp., Eutinobothrus, Frankliniella spp., Bollworm (Helicoverpa spp.), Heliothis spp., Heterotermes spp., Horcias, Lepidosaphes spp., Liogenys, Mahanarva spp., Myzus spp., Neoleucinodes spp., Nezara spp., Oncometopia, Orthezia spp., Parlatoria spp. .), Pectinophora spp., Procornitermes spp., Selenaspidus spp., Sternechus spp., Thrips spp. , Tuta; especially Agriotes spp., Alabama argillacea, Anthonomus grandis, Anticarsia gemmatalis, Aphis craccivora ), Aphis gossypii, Aracanthus mourei, Bemicia tabaci, Bemisia tabaci, Brevicoryne brassicae, Caliothrips brasiliensis, Capitophorus fragaefolli, Captophorus fragaefolii, Diabrotica speciosa (Diaphorina citri), Dilobopterus costalimai, Ecdytolopha urantiana, South American corn seedling moth (Elasmopalpus lignosellus), Empoasca kraemeri, Empoasca spp., Enneothrips flavens, Apple cotton aphid (Elasmopalpus lignosellus) Eutinobothrus brasiliensis, Frankliniella schultzei, Helicoverpa zea, Heliothis virescens, Sugarcane termites (Heterotermes tenuis), Concave giant stink bug (Horcias nobilellus), Lepidosaphes ulmi, Liogenys fuscus, Mahanarva fimbriolata, Myzus persicae, Neoleucinodes elegantalis, Southern green stinkbug (Nezara viridula), Oncometopia facialis, Orthezia praeinerealator ), red bell wheat moth (Pectinophora gossypiella), Procornitermes triacifer, Selenaspidus articulates, Sternechus subsignatus, Thrips palmi, Thrips tabaci, Tuta absoluta.

The composition of the present invention exhibits unexpectedly high effectiveness in controlling insect infestation, which is caused by the following: Citrus psyllids (Diaphorina citri), Dilobopterus costalimai, Ecdytolopha aurantiana on citrus (eg orange, lemon) , Oncometopia facialis, Orthezia praelonga, Parlatoria cinerea, Selenaspidus articulates; Agriotes spp. on cotton, Alabama argillacea, Mexican cotton boll Elephant (Anthonomus grandis), Cotton aphid (Aphis gossypii), Bemisia tabaci (Bemisia tabaci), Cotton gray elephant variant (Eutinobothrus brasiliensis), Comb-deficient thrips (Frankliniella schultzei), Tobacco budworm (Heliothis virescens), Concave giant stink bug (Horcias nobilellus), red bell wheat moth (Pectinophora gossypiella), tobacco thrips (Thrips tabaci); anticarsia gemmatalis on dried beans, black bean aphid (Aphis craccivora), tobacco powder Lice (Bemisia tabaci), Caliothrips brasiliensis, South American leaf beetle (Diabrotica speciosa), Empoasca kraemeri, Enneothrips flavens, southern green stink bug (Nezara viridula), Thrips palmidry; cotton aphid (Aphis gossypii) on fruits (e.g., papaya and pepper) , Bemisia tabaci (Bemisia tabaci), Capitophorus fragaefolli, Captophorus fragaefolii, Diabrotica speciosa (Diabrotica speciosa), Small green leafhopper (Empoasca spp.), Apple cotton aphid (Eriosoma lanigerum), Combed thrips (Frankliniella schultzei) , Helicoverpa zea, Lepidosaphes ulmi, Myzus persicae, Neoleucinodes elegantalis; Anticarsia gemmatalis, Aracanthus mourei, Bemicia on soybeans tabaci, South American leaf beetle (Diabrotica speciosa), South American corn seedling moth (Elasmopalpus lignosellus), Enneothrips flavens, Liogenys fuscus, southern green stink bug (Nezara viridula), Procornitermes triacifer, soybean stem elephant (Sternechus subsignatus); sugarcane on white ant (Heterotermes tenuis), Mahanarva fimbriolata, Procornitermes triacifer; Bemisia tabaci (Bemisia tabaci), Brassica aphid (Brevicoryne brassicae), Helicoverpa zea, Neoleucinodes on vegetables (eg, eggplant, cabbage, tomato, potato) elegantalis; and cotton aphid (Aphis gossypii), Bemisia tabaci, Capitophorus fragaefolli, Captophorus fragaefolii, Diabrotica speciosa, Diabrotica speciosa ( Empoasca spp.), Apple cotton aphid (Eriosoma lanigerum), comb-deficient thrips (Frankliniella schultzei), Helicoverpa zea, Lepidosaphes ulmi, Myzus persicae, Neoleucinodes elegantalis.

The composition according to the present invention is suitable for plants of the following crops: cereals (wheat, barley, rye, oats, corn, rice, sorghum, triticale and related crops); fruits such as pears, stone fruits and soft fruits such as apples , Grapes, pears, plums, peaches, papaya, almonds, pistachios, cherries, and berries (for example, strawberries, raspberries, and blackberries), bell peppers, peppers; legumes (beans, lentils, peas, soybeans, dried beans) ); oil plants (canola, mustard, sunflower); Cucurbitaceae (summer squash, cucumber, melon, watermelon); fiber plants (cotton, flax, hemp, jute); citrus, such as calamondin (calamondin), round bergamot (citrus citron), citrus hybrids (including chironja, tangelo, tangor), grapefruit, kumquat, lemon, lime, citrus (orange), lime, sweet Orange, grapefruit, and satsuma mandarin; vegetables (eggplant, spinach, lettuce, asparagus, cabbage, carrot Bougainvillea, onions, tomatoes, potatoes, red peppers); coffee; sugar cane; together with ornamental plants (flowers (such as roses), shrubs, broad-leaved trees, and evergreen trees (such as conifers)).

The composition of the present invention can be applied to citrus, fiber plants, fruits, legumes, cucurbitaceae, sugar cane and vegetables. Similarly, the composition of the present invention can be applied to papaya, pepper, soybean, dried beans, cucumber, melon, watermelon, cotton, orange, eggplant, cabbage, tomato, potato and sugar cane.

In one embodiment, the composition of the present invention is particularly effective in controlling the following aspects: Citrus psyllids (Diaphorina citri), Dilobopterus costalimai, Ecdytolopha aurantiana, Oncometopia facialis, Orthezia praelonga , Parlatoria cinerea, Selenaspidus articulatus (Selenaspidus articulatus); Agriotes spp. on cotton, Alabama argillacea, Mexican boll elephant (Anthonomus grandis) ), Aphis gossypii, Bemisia tabaci, Eutinobothrus brasiliensis, Frankliniella schultzei, Heliothis virescens, Heliothis virescens Long bug (Horcias nobilellus), red bell wheat moth (Pectinophora gossypiella), tobacco thrips (Thrips tabaci); dry bean moth (Anticarsia gemmatalis), black bean aphid (Aphis craccivora), tobacco whitefly (Bemisia tabaci) ), Caliothrips brasiliensis, South American leaf beetle (Diabrotica speciosa), Empoasca kraemeri, Enneothrips flavens, southern green stink bug (Nezara viridula), Thrips palmidry; cotton aphid (Aphis gossypii) on fruits (for example, papaya and pepper), Bemisia tabaci (Bemisia tabaci), Capitophorus fragaefolli, Captophorus fragaefolii, Diabrotica speciosa, Empoasca spp., Apple cotton aphid (Eriosoma lanigerum), combed thrips (Frankliniella schultzei), Gu Shiye Moth (Helicoverpa zea), Lepidosaphes ulmi, Myzus persicae, Neoleucinodes elegantalis; Anticarsia gemmatalis on soybeans, Aracanthus mourei, Bemicia tabaci, Diabrotica speciosa, South American corn seedlings Spot borer (Elasmopalpus lignosellus), Enneothrips flavens, Liogenys fuscus, southern green stink bug (Nezara viridula), Procornitermes triacifer, soybean stem elephant (Sternechus subsignatus); sugarcane termite (Heterotermes tenuis) on sugarcane (Heterotermes tenuis), Maachanar va For example, Bemisia tabaci (Bemisia tabaci), Brevicoryne brassicae, Helicoverpa zea, Neoleucinodes elegantalis on eggplant, cabbage, tomato, potato; and Cucurbitaceae (e.g., cucumber, melon, watermelon) ) On cotton aphid (Aphis gossypii), Bemisia tabaci (Bemisia tabaci), Capitophorus fragaefolli, Captophorus fragaefolii, South American leaf beetle (Diabrotica speciosa), Empoasca spp., Apple cotton aphid (Eriosoma lanigerum), Frankliniella schultzei (Frankliniella schultzei), Helicoverpa zea, Lepidosaphes ulmi, Myzus persicae, Neoleucinodes elegantalis; by applying a cloth containing three components ((A) The plant, its plant parts and/or the surrounding environment treated with the synergistic insecticidal composition of Fengin, (B) Celonine and (C) Celonine), wherein the component (A) and the component in the composition The weight ratio of (B) is about 2:1 to about 3:1; and wherein the weight ratio of component (A) to component (C) in the composition is from about 4:1 to 6:1.

The composition of the present invention can be applied to the leaves or seeds or fruits of plants or their surrounding environment.

The present invention also relates to the use of the insecticidal composition as described herein for preventing, controlling and/or treating plants, plant parts and/or their surrounding environment of insect infestation.

The composition of the present invention may contain or mix other pesticides such as fungicides, other herbicides and nematicides, growth factor enhancers, and fertilizers.

The application (use) rate of the composition of the present invention can vary according to, for example, the type of use, crop type, specific active compound in the combination, and plant type, but it allows the active compound in the combination to be applied in an effective amount to provide the desired Role (such as insect or pest control). The application rate of the composition for a given set of conditions can be easily determined by experimentation.

Components (A), (B) and (C) and any other pesticides can be applied and used in pure form, as solid active compounds, for example, in a specific particle size, or preferably with adjuvants or adjuvant components At least one of them is applied and used together, as is customary in formulation technology, such as extenders, for example, solvents or solid carriers, or surface active compounds (surfactants), as described in more detail above. Generally, components (A), (B) and (C) are in the form of a formulation composition with one or more of the aforementioned conventional formulation auxiliaries.

Examples of the types of formulations used for the premix composition are: water-soluble liquid (SL), emulsion (EC), water-based emulsion (EW), microemulsion (ME), water-dispersible oil suspension (OD), Seed treatment water suspension (FS), water dispersible granules (WG), water-soluble granules (SG), wettable powder (WP), water-soluble powder (SP), granules (GR), capsule granules (CG), fine granules (FG), large granules (GG), concentrated suspension emulsion (SE), capsule suspension (CS), microparticles (MG) or preferably aqueous suspension (SC), water dispersion Granules (WG) and Emulsion (EC).

Direct (i.e. undiluted) use or dilution with a suitable solvent (especially water) After using such formulations, the plants, plant parts and/or their surroundings can be treated by spraying, pouring or immersing and protecting them from insects. The formulation can be diluted with water at a ratio of from about 50 to about 1500 g total active ingredient per hectare, preferably from about 50 to about 1000 g total active ingredient per hectare, more preferably from about 50 to about 50 per hectare. The ratio of about 500 g total active ingredient is optimally from about 150 to about 250 g total active ingredient per hectare.

Preferably, from about 1-1000g/ha of component (A), from about 1-200g/ha of component (B), and from about 1-200g/ha of component (C); more preferably , From about 50-500g/ha component (A), from about 5-100g/ha component (B), and from about 5-100g/ha component (C); best, from about 50-200 g/ha component (A), from about 20-75 g/ha component (B), and from about 10-75 g/ha component (C).

The compositions or components (A), (B) and (C) can be applied using any method known in the art. These methods include coating, spraying, dipping, soaking, injection, irrigation, etc.

The active ingredients (A), (B), and (C) can be applied simultaneously or continuously at short intervals (for example, on the same day) to the plants, plant parts, and/or their surrounding environment to be controlled. The components (A), (B) and (C) may be applied to the plant, one or more plant parts (such as leaves or seeds), or its surrounding environment in any order. Each component can be applied only once or multiple times. Preferably, each of the components (A), (B) and (C) is applied multiple times, especially 2 to 5 times, more preferably 1-3 times per season.

The active ingredients (A), (B) and (C) can be administered in any suitable form as described above. Typically, the active ingredient will be administered as a formulation, ie a composition comprising one or more active ingredients together with additional carriers, surfactants or other adjuvants conventionally used in formulation techniques to facilitate administration.

If components (A), (B) and (C) are applied simultaneously, they can be used as Application of a composition comprising components (A), (B) and (C), wherein components (A), (B) and (C) can be obtained from separate formulation sources and mixed together (known as barrels) Mixed, ready-to-use, spray liquid or slurry), optionally mixed with other pesticides, or components (A), (B) and (C) can be obtained from a single formulation mixture source (known as pre-mixed , Concentrates, formulated compounds (or products)), and optionally mixed with other pesticides.

The composition according to the invention is particularly well tolerated by plants and is environmentally friendly.

Each composition according to the invention is particularly advantageous for the treatment of plants.

The following examples are given by way of illustration and not by way of limiting the invention.

Examples of formulations

By combining the finely ground active ingredients and additives (0.5% SUPRALATE ^® (sodium lauryl sulfate, Witco Inc.), Greenwich (Greenwich), 5% REAX ^® 88B (sodium lignosulfonate, Westvaco Corp., potassium carbonate (balanced to 100%) were mixed and then extruded and dried in a jet dryer to prepare water dispersible granules (WG).

碳酸鉀 32.25% E.g,

Potassium carbonate 32.25%

By combining the finely ground active ingredients and additives (100g propylene glycol, 50g tristyrylphenol ethoxylate, 10g sodium lignosulfonate, 10g carboxymethyl cellulose, 10g silicone oil (in the form of 75% water emulsion) ), 1g of xanthan gum, 1g of NIPACIDE BIT 20, water (make up to 1L)) were mixed to prepare an aqueous suspension (SC).

E.g,

The emulsion (EC) was prepared by mixing the active ingredients with the adjuvants (50 g tristyryl phenol ethoxylate, 1 g silicone oil, 300 g N-methylpyrrolidone, SOLVESSO 200 (make up to 1 L)).

E.g,

Biological examples

When the activity of a composition containing two or more active compounds is greater than the sum of the activities of the various active compounds administered alone, then the combination of two or more active compounds has a synergistic effect. The expected activity of a given combination of two active compounds can be calculated by the so-called "Colby formula" (see SR Colby, "Calculating Synergistic and Antagonistic Responses of Herbicide Combinations", Weeds ( Weeds) 1967, 15, 20-22): where: A=when active compound A is used at an application rate of mg/ha, the percentage of activity of compound A; B=when active compound B is used at an application rate of ng/ha When, the activity percentage of compound B; E ₁ = when compound A and B are used together at the application rate of mg/ha and ng/ha, estimate the percentage of activity; then: E ₁ =A+B-(A×B/ 100).

If the actual activity observed for the combination of compounds A and B is greater than the calculated activity (E ₁ ), then the activity of the combination is superadditive. In other words, synergy exists.

The expected activity of a given combination of three active compounds can be calculated by the "Colby formula" (SR Colby, Weeds 15, 20-22, 1967), namely E=(A+B+C)-(A×B+A× C+B×C)/100+A×B×C/10000

By virtue of A = when compound A is used at a dose of m (g/ha), the percentage efficacy of compound A; B = when compound B is used at a dose of n (g/ha), the percentage efficacy of compound B; C = when When compound C is used at the dose of p(g/ha), the percentage efficacy of compound C; E ₂ = when used together at the doses of m(g/ha), n(g/ha) and p(g/ha) Estimated percentage efficacy of compounds A and B and C.

If the actual activity observed for a combination of compounds A, B, and C is greater than the calculated activity (E ₂ ), then the activity of the combination is superadditive. In other words, synergy exists.

Field trial 1-orange-psyllid ( Diaphorina citri ), aphids (Dilobopterus costalimai), beetle (Ecdytolopha aurantiana)

Psyllids ( Diaphorina citri ), aphids (Dilobopterus costalimai), and beetles (Ecdytolopha aurantiana) are cultivated in the laboratory. The number of insects was counted, the insects were collected and then placed on different healthy young orange plants. The formulation is diluted and applied. After being kept in a greenhouse at 21°C-25°C and 80% relative atmospheric humidity for 10 days, the remaining populations of insects were examined. (Table A)

Field trial 2-orange-leafhopper (Oncometopia facialis), moth (Orthezia praelonga), scale insect (Parlatoria cinerea), scale insect (Selenaspidus articulatus)

Leafhoppers (Oncometopia facialis), moths (Orthezia praelonga) larvae and scale insects (Parlatoria cinerea and Selenaspidus articulatus) were cultured in the laboratory. The number of insects was counted, the insects were collected and then placed on different healthy young orange plants. The formulation is diluted and applied. After being kept in a greenhouse at 21°C-25°C and 80% relative atmospheric humidity for 10 days, the remaining populations of insects were examined. (Table B)

Table B:

Field trial 3-Cotton-beetle (Agriotes spp.), cotton boll weevil (Anthonomus grandis), cotton bug (Horcias nobilellus) ), cotton root borer (Eutinobothrus brasiliensis)

Breeding beetles (Agriotes spp.), cotton boll weevil (Anthonomus grandis), cotton bugs (Horcias nobilellus) ), cotton root borer (Eutinobothrus brasiliensis). The number of insects is counted, the insects are collected and then placed on different healthy young cotton plants. The formulation is diluted with water and then applied to the plants. After being kept in a greenhouse for 10 days at 21°C-25°C and 80% relative atmospheric humidity, the remaining populations of bed bugs were examined. (Table C)

Field trial 4-cotton-moth (Alabama argillacea), moth (Heliothis virescens), red bollworm (Pectinophora gossypiella)

The larvae of moths (Alabama argillacea and Heliothis virescens) and red bollworm (Pectinophora gossypiella) were cultured in the laboratory. The number of insects is counted, the insects are collected and then placed on different healthy young cotton plants. The example formulation is diluted with water and then applied to the plants. After being kept in a greenhouse for 10 days at 21°C-25°C and 80% relative atmospheric humidity, the remaining populations of mites were examined. (Table D)

Field trial 5-Cotton-Thrips (Frankliniella schultzei), Thrips (Thrips tabaci), Whitefly (Bemisia tabaci)

Thrips (Frankliniella schultzei), thrips (Thrips tabaci), and whiteflies (Bemisia tabaci) are cultivated in the laboratory. The number of insects is counted, the insects are collected and then placed on different healthy young cotton plants. The example formulation is diluted with water and then applied to the plants. After being kept in a greenhouse for 10 days at 21℃-25℃ and 80% relative humidity, the remaining populations of thrips were examined _[RW3] . (Table E)

Field trial 6-dry beans-aphid (Aphis craccivora), gourd beetle (Diabrotica speciosa), leafhopper (Empoasca kraemeri)

Aphids (Aphis craccivora), gourd beetles (Diabrotica speciosa), and leafhoppers (Empoasca kraemeri) are cultivated in the laboratory. The number of insects was counted, the insects were collected and then placed on different healthy young dry bean plants. The formulation is diluted with water and then sprayed on the plants. After being kept in a greenhouse at 21°C-25°C and 80% relative atmospheric humidity for 10 days, the remaining populations of insects were examined. (Form F)

Field Test 7-Dried Bean-Moth (Anticarsia gemmatalis), Stinkbug (Nezara viridula), Whitefly (Bemisia tabaci)

Moths (Anticarsia gemmatalis) larvae, stink bugs (Nezara viridula) and whiteflies (Bemisia tabaci) were cultured in the laboratory. The number of insects was counted, the insects were collected and then placed on different healthy young dry bean plants. The example formulation is diluted with water and then applied to the plants. After being kept in a greenhouse at 21°C-25°C and 80% relative atmospheric humidity for 10 days, the remaining populations of insects were examined. (Table G)

Field trial 8-dry beans-thrips (Caliothrips brasiliensis), thrips (Enneothrips flavens), thrips (Thrips palmi)

Thrips (Caliothrips brasiliensis, Enneothrips flavens, and Thrips palmi) were cultivated in the laboratory. The number of insects was counted, the insects were collected and then placed on different healthy young dried bean plants. The example formulation is diluted with water and then applied to the plants. After being kept in a greenhouse at 21℃-25℃ and 80% relative humidity for 10 days, the remaining populations of thrips were examined _[RW4] . (Table H)

Field trial 9-Papaya-Aphid (Aphis gossypii, Capitophorus fragaefolli, Apple cotton aphid (Eriosoma lanigerum), Myzus persicae)

Aphids (Aphis gossypii, Capitophorus fragaefolli, Eriosoma lanigerum, Myzus persicae) were cultivated in the laboratory. The number of insects was counted, the insects were collected and then placed on different healthy young papaya plants. The example formulation is diluted and then applied to the plants. After being kept in a greenhouse at 21°C-25°C and 80% relative atmospheric humidity for 10 days, the remaining populations were examined. (Table I)

Field trial 10-pepper-beetle (Diabrotica speciosa), leafhopper (Empoasca spp.), scale insect (Lepidosaphes ulmi), thrips (Diabrotica speciosa) Horse (Frankliniella schultzei), whitefly (Bemisia tabaci)

The beetles (Diabrotica speciosa), leafhoppers (Empoasca spp.), scale insects (Lepidosaphes ulmi) and thrips (Diabrotica speciosa), leafhoppers (Empoasca spp.), scale insects (Lepidosaphes ulmi) Horse (Frankliniella schultzei), whitefly (Bemisia tabaci). The number of insects was counted, the insects were collected and then placed on different healthy young pepper plants. The example formulation is diluted and then applied to the plants. After being kept in a greenhouse at 21°C-25°C and 80% relative atmospheric humidity for 10 days, the remaining populations were examined. (Table J)

Field trial 11-papaya-moth (Helicoverpa zea, Neoleucinodes elegantalis, Tuta absoluta)

The larvae of moths (Helicoverpa zea, Neoleucinodes elegantalis, and Tuta absoluta) were cultured in the laboratory. The number of insects was counted, the insects were collected and then placed on different healthy young papaya plants. The formulation is diluted and then applied to the plants. After being kept in a greenhouse at 21°C-25°C and 80% relative atmospheric humidity for 10 days, the remaining populations were examined. (Table K)

Field trial 12-Soybean-beetle (Aracanthus mourei), beetle (Liogenys fuscus), gourd beetle (Diabrotica speciosa)

The beetles (Aracanthus mourei), beetles (Liogenys fuscus), and gourd beetles (Diabrotica speciosa) were cultivated in the laboratory. The number of insects was counted, the insects were collected and then placed on different healthy young soybean plants. The formulation is diluted and then sprayed on the plants. After being kept in a greenhouse at 21°C-25°C and 80% relative atmospheric humidity for 10 days, the remaining populations were examined. (Table L)

Field Test 13-Soybean-Moth (Anticarsia gemmatalis), Moth (Elasmopalpus lignosellus), Whitefly (Bemicia tabaci)

Moths (Anticarsia gemmatalis and Elasmopalpus lignosellus) larvae and whiteflies (Bemicia tabaci) were cultured in the laboratory. The number of insects was counted, the insects were collected and then placed on different healthy young soybean plants. The formulation is diluted and then sprayed on the plants. After being kept in a greenhouse at 21°C-25°C and 80% relative atmospheric humidity for 10 days, the remaining populations were examined. (Table M)

Field trial 14-Soybean-Stinkbug (Nezara viridula), Termites (Procornitermes triacifer), Thrips (Enneothrips flavens), Elephant Cape (Sternechus subsignatus)

Stinkbugs (Nezara viridula), termites (Procornitermes triacifer), thrips (Enneothrips flavens), and Cape elephants (Sternechus subsignatus) are cultivated in the laboratory. The number of insects was counted, the insects were collected and then placed on different healthy young soybean plants. The formulation is diluted and then applied to the plants. After being kept in a greenhouse at 21°C-25°C and 80% relative atmospheric humidity for 10 days, the remaining populations were examined. (Table N)

Field trial 15-Sugarcane-Mahanarva fimbriolata, Termites (Heterotermes tenuis), Termites (Procornitermes triacifer), Aphids (Brevicoryne brassicae)

Cicadas (Mahanarva fimbriolata), termites (Heterotermes tenuis), termites (Procornitermes triacifer), and aphids (Brevicoryne brassicae) were cultivated in the laboratory. Count and collect insects And then placed on different healthy young sugarcane plants. The formulation is diluted and then applied to the plants. After being kept in a greenhouse at 21°C-25°C and 80% relative atmospheric humidity for 10 days, the remaining populations were examined. (Table O)

Field trial 16-sugarcane-moth (Helicoverpa zea), moth (Neoleucinodes elegantalis), whitefly (Bemisia tabaci)

The larvae and whiteflies (Bemisia tabaci) of moths (Helicoverpa zea and Neoleucinodes elegantalis) were cultured in the laboratory. The number of insects was counted, the insects were collected and then placed on different healthy young sugarcane plants. The formulation is diluted and then sprayed on the plants. After being kept in a greenhouse at 21°C-25°C and 80% relative atmospheric humidity for 10 days, the remaining populations were examined. (Table P)

All publications, patents, and patent applications cited in this specification are incorporated herein by reference, just as each publication or patent application is specifically and individually indicated to be incorporated herein by reference. Although the above invention has been described in some details for the purpose of clarity by way of illustration and examples, it is easy for those skilled in the art to understand the disclosure of the present invention that it can be changed and modified in different ways. Deviate from the spirit or scope of the attached claims.

Throughout this specification and the attached claims, unless the context requires otherwise, the words "comprise" and "include" and various variations such as "comprising" and "including" shall It is understood to mean the stated whole or a group of multiple wholes, but does not exclude any other whole or a group of multiple wholes.

The reference to any prior art in this specification is not, and should not be taken as an acknowledgement or in any form to indicate that such prior art forms part of general general knowledge.

Claims (16)

An insecticidal composition comprising three components: (A) buprofezin, (B) thiamethoxam and (C) lambda-cyhalothrin. The composition according to claim 1, wherein the component (A) ibufungin is present in an amount from 1% to 75% by weight of the composition, and the component (B) celsuan is in the combination The content is present in an amount from 0.1% to 50% by weight, and the component (C) Xeronin is present in an amount from 0.1% to 50% by weight of the composition. The composition according to claim 1 or 2, wherein the weight ratio of component (A) to component (B) in the composition is independently in the range from 99:1 to 1:99. The composition according to claim 1 or 2, wherein the weight ratio of component (A) to component (C) in the composition is independently in the range from 99:1 to 1:99. The composition according to claim 3, wherein the weight ratio of the component (A) to the component (B) in the composition is in the range of from 15:1 to 1:1. The composition according to claim 3, wherein the weight ratio of component (A) to component (B) in the composition is in the range from 12:1 to 1:1. The composition according to claim 3, wherein the weight ratio of component (A) to component (B) in the composition is in the range from 8:1 to 1:1. The composition according to claim 4, wherein the weight ratio of component (A) to component (C) in the composition is in the range from 15:1 to 1:1. The composition according to claim 4, wherein the weight ratio of component (A) to component (C) in the composition is in the range from 12:1 to 1:1. The composition according to claim 4, wherein the weight ratio of component (A) to component (C) in the composition is in the range from 8:1 to 1:1. The composition according to claim 1 or 2, which further comprises one or more additives selected from the following: extenders, carriers, solvents, surfactants, stabilizers, defoamers, antifreeze agents , Preservatives, antioxidants, colorants, thickeners, solid adhesives and inert fillers. A use of the composition according to any one of claims 1 to 11, which is used to prevent, control and/or treat plants, plant parts and/or their surrounding environment from insect infestation. The use according to claim 12, wherein the insects are selected from the group consisting of aphids, marching insects, beetles, cotton bollworms, heart worms, pickle insects, burrowing insects, borers, caterpillars, citrus scales, and large southern white butterflies , Leafhoppers, leaf miners, loopers, millipedes, paraphagous mites, moths, spider mites, foam cicadas, stink bugs, termites, thrips, elephant capes, whiteflies, worms and psyllids. The use according to claim 12 or 13, wherein the plant, plant part or its surrounding environment is selected from the group consisting of citrus, fiber plants, fruits, legumes, cucurbitaceae, sugarcane and vegetables. A method for preventing, controlling and/or treating insect infestation in plants, plant parts and/or their surrounding environment, the method comprising applying three components to said plants, plant parts and/or their surrounding environment: (A ) Bufungin, (B) Saxon, and (C) Celonine. The method according to claim 15, which comprises applying the composition according to any one of claims 1 to 11 to these plants, plant parts and/or their surrounding environment.