CN115530175A - Agrochemical combinations - Google Patents
Agrochemical combinations Download PDFInfo
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- CN115530175A CN115530175A CN202211120851.0A CN202211120851A CN115530175A CN 115530175 A CN115530175 A CN 115530175A CN 202211120851 A CN202211120851 A CN 202211120851A CN 115530175 A CN115530175 A CN 115530175A
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- fungicide
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- fungicides
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P21/00—Plant growth regulators
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P3/00—Fungicides
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
- A01N47/14—Di-thio analogues thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/18—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
Abstract
The present invention relates to agrochemical combinations. Disclosed are a combination and a composition comprising the combination, the combination comprising: at least one multi-site contact fungicide and at least one plant health promoting agent. The plant health promoting additive greatly improves the disease control of the combination of dithiocarbamate and benzimidazole fungicides.
Description
The application is a divisional application of international application PCT/IB2018/057950 entering China at 18.5.2020, with the application number of 201880074490.6 and the name of invention of 'novel agrochemical combination'.
Technical Field
The present invention relates to synergistic combinations comprising fungicides and plant health promoters. The combinations are very suitable for controlling harmful phytopathogenic fungi.
Background
Fungicides are an indispensable and important tool for farmers to control diseases and to improve crop yield and quality. Over the years, various fungicides have been developed with many desirable attributes, such as specificity, systemic, curative and eradication, and high activity at low rates of use.
Benzimidazole fungicides are known in the art as broad spectrum fungicides. These fungicides prevent nuclear cell division, making them potent fungicides. Their broad spectrum of use makes them ideal tools for controlling various fungal diseases.
Multisite fungicides are known in the art as broad spectrum fungicides. Dithiocarbamates are known in the art as multi-site fungicides. These fungicides are used for broad-spectrum disease control in more than 70 crops. Mancozeb is particularly important for controlling destructive and rapidly spreading diseases such as Phytophthora infestans (Phytophthora infestans), apple scab (Venturia inaegulis), etc. Dithiocarbamate fungicides, in particular mancozeb, are particularly useful for disease control due to their broad spectrum of activity, high tolerance of crops, and general usefulness for controlling fungal plant diseases that are not controlled by active compounds acting only at a single target site in the fungus.
Various plant health promoting agents are known in the art, including fertilizers, biologicals, and plant additives that promote growth and increase plant yield. Elemental silica is the second most abundant element in the earth's crust. Various studies have been carried out to demonstrate the importance of silica in plant growth. Studies have also shown that silica is ingested in the same amount as any other known micronutrient (Role of Orthosilicic Acid (OSA) -Based Formulation in Improving Plant Growth and Development, jain et al, silicon (2016) (Role of Orthosilicic Acid (OSA) -Based Formulation in Improving Plant Growth and Development, jain et al, silicon, 2016)). A number of silica-based fertilizers and plant growth promoters are known in the art. However, none is mixed with a combination of fungicide and insecticide.
Combinations of mancozeb and carbendazim are known in the art. CN103081932a teaches WP preparation of this combination. However, this combination does not contribute to improving the health of the plant, and the combination of mancozeb and carbendazim is synergistic beyond the known range.
IN250155 teaches that the combination of mancozeb and carbendazim enhances the biological efficacy of the combination when mixed with urea. However, the addition of urea does not satisfactorily improve the performance of the combination nor does it contribute to the improvement of disease resistance.
Disclosure of Invention
Thus, there is a need in the art for a combination of fungicides and plant health promoting agents that helps improve the spectrum and promote greater plant health, and increase yield. As crop tolerance decreases, lower rates of use are applied and resistance is increasingly observed, there is a need for combinations of actives that allow a broader spectrum of disease control and improved plant health, which combine curative and preventive actives with lower dosages.
Accordingly, embodiments of the present invention may ameliorate one or more of the above problems:
object of the Invention
Thus, embodiments of the present invention may provide a combination of a fungicide and a plant health promoting agent that has enhanced efficacy over the individual active compounds used in isolation.
It is another object of the present invention to provide a combination of a fungicide and a plant health promoter which results in enhanced greening of the crop to which it is applied.
It is another object of the present invention to provide such a combination: this combination results in increased crop yield when applied to the locus of the plant.
It is a further object of the present invention to provide such a combination: this combination results in a reduced incidence of fungal disease in the crops to which it is applied.
It is another object of the present invention to provide such a combination: the combination achieves increased yield in the crop to which it is applied.
It is another object of the present invention to provide such a combination: this combination results in an enhanced fungicidal activity.
Some or all of these and other objects of the invention may be achieved by the invention described below.
Summary of The Invention
Accordingly, one aspect of the present invention may provide a combination comprising: at least one multi-site contact fungicide and at least one plant health promoting agent.
Accordingly, one aspect of the present invention may provide a combination comprising: at least one multi-site contact fungicide; at least one other fungicide and at least one plant health promoting agent.
Accordingly, one aspect of the present invention may provide a combination comprising: at least one multisite contact fungicide; at least one strobilurin fungicide and at least one plant health promoting agent.
Accordingly, one aspect of the present invention may provide a combination comprising: at least one dithiocarbamate fungicide; at least one benzimidazole fungicide and at least one plant health promoting agent.
Another aspect of the invention may provide a combination comprising: at least one dithiocarbamate fungicide; at least one benzimidazole fungicide selected from albendazole, benomyl, carbendazim, chlorofenazole, cyhalonil, imicarb, fuberidazole, mefenbendazole, imazalil, thiabendazole; and at least one plant health promoting agent.
Detailed Description
As used herein, the term "disease control" indicates the control and prevention of diseases. The control effect includes all deviations from natural development, for example: killing fungal diseases, delaying fungal diseases and reducing fungal diseases. The term "plant" refers to all physical parts of a plant, including seeds, seedlings, plantlets, roots, tubers, stems, stalks, leaves, and fruits. As used herein, the term "locus" of a plant is intended to encompass a place where a plant is growing, where the plant propagation material of the plant is sown, or where the plant propagation material of the plant is to be placed in soil. The term "plant propagation material" is understood to mean the reproductive parts of plants, such as seeds, vegetative materials such as cuttings or tubers, roots, fruits, tubers, bulbs, rhizomes and parts of plants, germinating plants and young plants to be transplanted after germination or after ground breaking. These young plants may be protected by a whole or partial immersion treatment prior to transplantation. The term "agriculturally acceptable amount of active material" refers to an amount of active material that kills or inhibits the plant disease to be controlled, which does not cause significant toxicity to the treated plant.
Surprisingly, it was found that the fungicidal activity and/or the plant vigor activity and/or the yield enhancing activity of the multi-site contact fungicides according to the invention is significantly higher in the presence of a plant health promoting agent.
It has surprisingly been found that the addition of a plant health promoting additive to a multi-site contact fungicide synergistically enhances the efficacy of the fungicide.
Thus, in one embodiment, the fungicidal activity of the multi-site contact fungicide in the presence of the plant health promoting agent of the present invention is surprisingly higher than in the absence of the plant health promoting agent.
In one embodiment, it has also been surprisingly found that the addition of a plant health promoting additive to a multi-site contact fungicide provides surprising and unexpected advantages. Surprisingly, the addition of a plant health promoting agent such as a silicic acid-based additive results in enhanced efficacy when combined with a multi-site contact fungicide, and the incidence of fungal disease is surprisingly reduced compared to the efficacy observed with a multi-site contact fungicide alone. It has also been found that the addition of plant health promoting additives to multi-site contact fungicides results in better greening of the crop plants, and greater yield of the crop plants to which they are applied.
These surprising advantages of the combination of the present invention are not observed when the health promoting additive is not added to the multi-site contact fungicide. Thus, these unexpected advantages of the combinations of the present invention can be attributed to the inclusion of plant health promoting additives in the multi-site contact fungicide.
Accordingly, one aspect of the present invention may provide a combination comprising: at least one multi-site contact fungicide and at least one plant health promoting agent.
Another aspect of the present invention may provide a composition comprising: at least one multi-site contact fungicide; at least one plant health promoting agent; and at least one agrochemically acceptable excipient.
In one embodiment, the plant health promoting agent may be added to a combination of the multi-site contact fungicide and at least one other systemic fungicide.
Surprisingly, it was found that the fungicidal activity and/or the plant vigor activity and/or the yield-enhancing activity of the active compound combinations according to the invention are significantly higher than the sum of the activities of the individual active compounds.
It has surprisingly been found that the addition of a plant health promoting additive to a fungicide combination synergistically enhances the efficacy of the combination.
Thus, in one embodiment, the fungicidal activity of a combination of a multisite contact fungicide and at least one other systemic fungicide in the presence of a plant health promoting agent of the present invention is surprisingly higher than in the absence of a plant health promoting agent.
In one embodiment, it has also been surprisingly found that the addition of a plant health promoting additive to a combination of a multisite contact fungicide and at least one other systemic fungicide, results in surprising and unexpected advantages. Surprisingly, the addition of a plant health promoting agent such as a silicic acid-based additive results in an enhanced efficacy when combined with a combination of a multi-site contact fungicide and at least another systemic fungicide, and the incidence of fungal disease is surprisingly reduced compared to the efficacy observed with the combination of a multi-site contact fungicide and at least another systemic fungicide alone. It has also been found that the addition of plant health promoting additives to a combination of a multi-site contact fungicide and at least one other systemic fungicide results in better greening of the crop plants and greater yield of the crop plants to which they are applied.
These surprising advantages of the combination of the present invention were not observed when the health promoting additive was not added to the combination. Thus, these unexpected advantages of the combinations of the present invention may be attributed to the inclusion of a plant health promoting additive in a combination of a multi-site contact fungicide and at least one other systemic fungicide.
Accordingly, in one aspect, the present invention provides a combination comprising:
(a) At least one multi-site contact fungicide; and
(b) A plant health promoting additive based at least on silicic acid.
In another aspect, the present invention provides a combination comprising:
(a) At least one multi-site contact fungicide;
(b) At least a silicic acid-based plant health promoting additive; and
(c) At least one agrochemically acceptable excipient.
Accordingly, in one aspect, the present invention provides a combination comprising:
(a) At least one multisite contact fungicide;
(b) At least one systemic fungicide; and
(c) A plant health promoting additive based at least on silicic acid.
In another aspect, the present invention provides a combination comprising:
(a) At least one multi-site contact fungicide;
(b) At least one systemic fungicide;
(c) A plant health promoting additive based on at least silicic acid; and
(d) At least one agrochemically acceptable excipient.
In one embodiment, the multi-site fungicide is selected from the group consisting of: dithiocarbamates, phthalimides, chloronitriles, inorganic fungicides, sulfonamides, biguanides, triazines, quinones, quinoxalines, dicarboxamides, and mixtures thereof.
In one embodiment, the multi-site fungicide is selected from the group of dithiocarbamate fungicides selected from the group consisting of amobam, arsine, thiram oxide, morbus, thiabendazole, copper oxychloride, disulfiram, ferbam, metam, sodium metiram, thiram, arsine, ziram, dazomet, thiobam, metiram, mancopper, mancozeb, maneb, metiram, polycarbamate, zineb and zineb.
Accordingly, in one aspect, the present invention provides a combination comprising:
(a) At least one dithiocarbamate fungicide selected from the group consisting of amobam, arsenic disulfide, thiram oxide, morbus, thiabendazole, copper oxychloride, disulfiram, ferbam, metam, sodium metiram, thiram, arsine, ziram, dazomet, thioneb, metiram, mancopper, mancozeb, maneb, metiram, polycarbamate, zineb and zineb; and
(b) A plant health promoting additive based at least on silicic acid.
In another aspect, the present invention provides a combination comprising:
(a) At least one dithiocarbamate fungicide selected from the group consisting of amobam, arsenic disulfide, thiram oxide, morbus, thiabendazole, copper oxychloride, disulfiram, ferbam, metam, sodium metiram, thiram, arsine, ziram, dazomet, thioneb, metiram, mancopper, mancozeb, maneb, metiram, polycarbamate, zineb and zineb;
(b) A plant health promoting additive based on at least silicic acid; and
(c) At least one agrochemically acceptable excipient.
Accordingly, in one aspect, the present invention provides a combination comprising:
(a) At least one dithiocarbamate fungicide selected from the group consisting of amobam, arsanilide, thiram oxide, dodemocarb, thiabendazole, copper oxychloride, disulfiram, ferbam, metam, sodium metiram, thiram, arsine, ziram, dazomet, thione, metiram, mancozeb, maneb, metiram, polycarbamate, propineb, and zineb;
(b) At least one systemic fungicide; and
(c) A plant health promoting additive based at least on silicic acid.
In another aspect, the present invention provides a combination comprising:
(a) At least one dithiocarbamate fungicide selected from the group consisting of amobam, arsanilide, thiram oxide, dodemocarb, thiabendazole, copper oxychloride, disulfiram, ferbam, metam, sodium metiram, thiram, arsine, ziram, dazomet, thione, metiram, mancozeb, maneb, metiram, polycarbamate, propineb, and zineb;
(b) At least one systemic fungicide;
(c) A plant health promoting additive based on at least silicic acid; and
(d) At least one agrochemically acceptable excipient.
In one embodiment, the multi-site fungicide is a phthalimide fungicide selected from captan, captafol, and folpet.
Accordingly, in one aspect, the present invention provides a combination comprising:
(a) At least one phthalimide fungicide selected from captan, captafol and folpet; and
(b) A plant health promoting additive based at least on silicic acid.
In another aspect, the present invention provides a combination comprising:
(a) At least a phthalimide fungicide selected from captan, captafol and folpet;
(b) A plant health promoting additive based on at least silicic acid; and
(c) At least one agrochemically acceptable excipient.
Accordingly, in one aspect, the present invention provides a combination comprising:
(a) At least one phthalimide fungicide selected from captan, captafol and folpet;
(b) At least one systemic fungicide; and
(c) A plant health promoting additive based at least on silicic acid.
In another aspect, the invention provides a combination comprising:
(a) At least a phthalimide fungicide selected from captan, captafol, and folpet;
(b) At least one systemic fungicide;
(c) A plant health promoting additive based on at least silicic acid; and
(d) At least one agrochemically acceptable excipient.
In one embodiment, the multisite fungicide is a chloronitrile fungicide, such as chlorothalonil.
Accordingly, in one aspect, the present invention provides a combination comprising:
(a) Chlorothalonil;
(b) A plant health promoting additive based at least on silicic acid.
In another aspect, the present invention provides a combination comprising:
(a) Chlorothalonil;
(b) A plant health promoting additive based on at least silicic acid; and
(c) At least one agrochemically acceptable excipient.
Accordingly, in one aspect, the present invention provides a combination comprising:
(a) Chlorothalonil;
(b) At least one systemic fungicide; and
(c) A plant health promoting additive based at least on silicic acid.
In another aspect, the present invention provides a combination comprising:
(a) Chlorothalonil;
(b) At least one systemic fungicide;
(c) A plant health promoting additive based on at least silicic acid; and
(d) At least one agrochemically acceptable excipient.
In one embodiment, the multisite fungicide is a sulfonamide fungicide selected from dichlofluanid and tolylfluanid.
In one embodiment, the multisite fungicide is a biguanide fungicide selected from the group consisting of iminoctadine and iminoctadine.
In one embodiment, the multisite fungicide is a triazine fungicide selected from the group consisting of trichlofop.
In one embodiment, the multi-site fungicide is a quinone fungicide selected from dithianon.
In one embodiment, the multi-site fungicide is selected from the group consisting of Dermatophagoides pteronyssinus and Tetrachloroquine
Quinoxaline fungicides of quinolines.
In one embodiment, the multi-site fungicide is a dicarboxamide fungicide selected from the group consisting of trifoliate.
In one embodiment, the multi-site fungicide is an inorganic fungicide selected from copper fungicides including copper (II) hydroxide, copper oxychloride, copper (II) sulfate, basic copper sulfate, bordeaux mixture, copper salicylate C 7 H 4 0 3 * Cu, cuprous oxide CU 2 O; or sulfur.
Accordingly, in one aspect, the present invention provides a combination comprising:
(a) At least one inorganic fungicide selected from copper fungicides including copper (II) hydroxide, copper oxychloride, copper (II) sulfate, basic copper sulfate, bordeaux mixture, copper salicylate C 7 H 4 0 3 * Cu, cuprous oxide CU 2 O; or sulfur; and
(b) A plant health promoting additive based at least on silicic acid.
In another aspect, the invention provides a combination comprising:
(a) At least one inorganic fungicide selected from copper fungicides including copper (II) hydroxide, copper oxychloride, copper (II) sulfate, basic copper sulfate, bordeaux mixture, copper salicylate C 7 H 4 0 3 * Cu, cuprous oxide CU 2 O; or sulfur;
(b) A plant health promoting additive based on at least silicic acid; and
(c) At least one agrochemically acceptable excipient.
Accordingly, in one aspect, the present invention provides a combination comprising:
(a) At least one inorganic fungicide selected from copper fungicides including copper (II) hydroxide, copper oxychloride, copper (II) sulfate, basic copper sulfate, bordeaux mixture, copper salicylate C 7 H 4 0 3 * Cu, cuprous oxide CU 2 O; or sulfur;
(b) At least one systemic fungicide; and
(c) A plant health promoting additive based at least on silicic acid.
In another aspect, the present invention provides a combination comprising:
(a) At least one inorganic fungicide selected from copper fungicides including copper (II) hydroxide, copper oxychloride, copper (II) sulfate, basic copper sulfate, bordeaux mixture, copper salicylate C 7 H 4 0 3 * Cu, cuprous oxide CU 2 O; or sulfur;
(b) At least one systemic fungicide;
(c) A plant health promoting additive based on at least silicic acid; and
(d) At least one agrochemically acceptable excipient.
In one embodiment, the plant health promoting additive according to the present invention is a silicic acid based additive selected from those having the following general formula:
[SiO x (OH) 4-2x ] n
in one embodiment, n varies from 6 to 200.
In one embodiment, x is 1.5 and n is 20.
In one embodiment, x is 1.5 and n is 8, or 6, or 10, or greater than 16.
In one embodiment, x is 1.5 and n is greater than 20.
In one embodiment, x is 1.5 and n is 36.
Such silicic acid can be selected from metasilicic acid (H) 2 SiO 3 ) Ortho silicic acid (H) 4 SiO 4 ) Disilicic acid (H) 2 Si 2 O 5 ) And pyrosilicic acid (H) 6 Si 2 O 7 ) (ii) a Preferably ortho-silicic acid, more particularly stable ortho-silicic acid.
In one embodiment, the selection of the systemic fungicide according to the present invention is not particularly limited. Such systemic fungicides may be selected from systemic fungicides for use together with multi-site contact fungicides, which form a preferred embodiment of the present invention.
In one embodiment, the systemic fungicide of the present invention may be a combination of two or more systemic fungicides. Thus, the following systemic fungicides described below can be used in the combination of the present invention alone or as a combination of two or more of the following systemic fungicides.
In one embodiment, the systemic fungicide is a succinate dehydrogenase inhibitor fungicide.
In one embodiment, the succinate dehydrogenase inhibitor is selected from succinate dehydrogenase inhibitor fungicides of the pyrazole carboxamides. However, it should be understood that the choice of succinate dehydrogenase inhibitor should not be construed as being limited to only these pyrazole carboxamide fungicides.
In one embodiment, the succinate dehydrogenase inhibitor fungicide of pyrazolecarboxamide may be selected from benzovindiflupyr, bixafen, fluxapyroxad, furametpyr, isopyrazam, penflufen, penthiopyrad, 3-difluoromethyl-N- (7-fluoro-1,1,3-trimethyl-4-indanyl) -l-methyl-4-pyrazolecarboxamide and sedaxane.
In one embodiment, the succinate dehydrogenase inhibitor fungicide can be selected from the group consisting of: mepiquat chloride, flutolanil, mefenapyr, iprodione, fluopyram, methylfurosemide, carboxin, thifluzamide, fluxapyroxad; iprodione and boscalid.
In one embodiment, the systemic fungicide of the present invention may be selected from nucleic acid synthesis inhibitors, cytoskeletal and motor protein inhibitors, amino acid and protein synthesis inhibitors, respiratory process inhibitors, signal transduction inhibitors, lipid synthesis and membrane integrity disruptors, sterol biosynthesis inhibitors, melanin synthesis inhibitors, cell wall biosynthesis inhibitors, host plant defense inducers, and/or fungicides with unknown mode of action.
Thus, in one embodiment, the systemic fungicide may be a nucleic acid synthesis inhibitor fungicide selected from the group consisting of: acylalanines such as benalaxyl, benalaxyl-M (kiralaxyl), furalaxyl, metalaxyl-M (mefenoxam),
oxazolidinones such as
Shuangling, butyrolactone such as methylfuroamide, hydroxy- (2-amino-) pyrimidines such as butylpyrimidine sulfonate, dimetrimol, ethirimol, iso-pyrimindine
Azoles such as hydroxymethyl
Azoles, isothiazolinones such as Xin Saitong, carboxylic acids such as
And (4) quinacid.
In one embodiment, the systemic fungicide may be a cytoskeletal and kinesin inhibitor selected from benzimidazoles such as benomyl, carbendazim, fuberidazole, thiophanate such as thiophanate, thiophanate-methyl, N-phenyl carbamates such as diethofencarb, toluamides such as zoxamide, thiazolecarboxamides such as ethaboxam, phenylureas such as pencycuron, benzamides such as fluopicolide, cyanoacrylates such as cyhalocarb.
<xnotran> , , , -5- , , , , , , , (mandestrobin), , , , , , , , , </xnotran>
Pyraclostrobin, fluoxastrobin, fenamidone, pyribencarb and mixtures thereof,
oxazolidinediones such as
Famoxadone, imidazolinones such as fenamidone, benzyl carbamates such as pyribencarb, N-methoxy- (phenyl-ethyl) -pyrazole-carboxamides such as pyrimidinamines (such as difluoroforest), cyanoimidazoles such as cyazofamid, sulfamoyltriazoles such as amethol, dinitrophenyl crotonates such as binapacryl, mepiquat, dinocap, 2,6-dinitroaniline such as fluazinam, hydrazones such as azone, triphenyltin compounds such as fentin, fentin chloride, fentin, thiophenecarboxamides such as silthiopham, triazolopyrimidinamines such as ametoctradin.
In one embodiment, the systemic fungicide may be an amino acid and protein synthesis inhibitor fungicide selected from the group consisting of an anilinopyrimidine such as cyprodinil, mepanipyrim, pyrimethanil, an antibiotic fungicide such as blasticidin-S, kasugamycin, streptomycin, oxytetracycline, and the like.
In one embodiment, the systemic fungicide may be a signal transduction inhibitor fungicide selected from the group consisting of aryloxyquinolines such as quinoxyfen, quinazolinones such as propoxyquinoline, phenylpyrroles such as fenpiclonil, fludioxonil, dicarboximides such as chlozolinate, dimethenamid, iprodione, procymidone and vinclozolin.
In one embodiment, the systemic fungicide may be a lipid synthesis and membrane integrity disrupter such as a thiophosphate such as diphenfos, iprobenfos, fenamiphos, dithianes such as isoprothiolane, aromatic hydrocarbons such as biphenyl, dicyclopentadine, clonidine, pentachloronitrobenzene (PCNB), tetraoxynitrobenzene (TCNB), tolclofos-methyl, etc., 1,2,4-thiadiazole such as terrazole, carbamate such as iodopropynyl butylcarbamate, propamocarb, thiocarb, etc.
Thus, in one embodiment, the systemic fungicide may be a sterol biosynthesis inhibitor selected from triazoles such as azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, metconazole, myclobutanil, penconazole, propiconazole, simeconazole, tebuconazole, tetraconazole, tricyclazoleAzolone, triadimenol, triticonazole, prothioconazole, piperazines such as fluazinam, pyridines such as pyribenzoxim, pyrimethanil
Azoles, pyrimidines such as fenarimol, fenarimol imidazoles such as imazalil,
Imidazole, pefurazoate, prochloraz, triflumizole, morpholines such as dimethylmorpholine, moroxydine, fenpropimorph, tridemorph and the like, piperidines such as fenpropidin, propamocarb, spirocuprammines such as spiroxamine, amides such as fenhexamid, aminopyrazolones such as fenpyrazamine, thiocarbamates such as pyributicarb, propionamides such as naftifine, terbinafine and mixtures thereof.
In one embodiment, the systemic fungicide may be a cell wall biosynthesis inhibitor fungicide selected from peptidyl pyrimidine nucleoside fungicides such as polyoxin, cinnamamides such as dimethomorph, flumorph, pyrimorph, valinamide carbamates such as benthiavalicarb, propineb, valicarb, mandelic acid amides such as mandipropamid and mixtures thereof.
In one embodiment, the systemic fungicide may be a melanin synthesis inhibitor fungicide selected from the group consisting of isobenzofuranones such as tetrachlorophthalide, pyrroloquinolinones such as pyroquilon, triazolobenzothiazoles such as tricyclazole, cyclopropanecarboxamides such as cyclopropylanilide, amides such as diclorocyanide, propionamides such as cyhalodiamide, trifluoroethylcarbamates such as topil Luo Ka (tolprocarb), and mixtures thereof.
In one embodiment, the systemic fungicide may be a host plant defense inducer fungicide selected from the group consisting of benzothiadiazoles such as acibenzolar-S-methyl, benzisothiazoles such as thiabendazole, thiadiazolecarboxamides such as tiadinil, isotianil, polysaccharides such as laminarin, and mixtures thereof.
In one embodiment, the systemic fungicide may be an adherent fungicideAn additional third or fourth fungicide selected from cyanoacetamide oximes such as cymoxanil, ethyl phosphonates such as fosetyl-aluminium, phosphoric acid and salts thereof, anthranilic acids such as phyllocilphthalide, benzotriazines such as imidazosin, benzenesulfonamides such as flusulfamide, pyridazinones such as pyridaben, thiocarbamates such as sulben, phenylacetamides such as cyflufenamid, arylphenones such as metrafenone, methoxybenzene cry bacteria, guanidines such as dodine, cyanomethylenethiazolidinediones such as fluanid (fluthianil), pyrimidinohydrazones such as pyriminohydrazone, piperidinylizathiazole isothiazole
Oxazolines such as ox Sha Puluo forest (oxathiapigenin), 4-quinolinylacetic esters such as tebucloquin (tebufloquin), tetrazolium ketoximes such as piccarbazol (picarbtrazox), glucopyranosyl antibiotics such as validamycin, fungicides such as mineral oil, organic oil, potassium bicarbonate and mixtures thereof.
In one embodiment, the preferred multisite fungicide may be selected from mancozeb, folpet, copper salts such as tribasic copper sulfate (TBCS), chlorothalonil and sulphur.
In one embodiment of the combination of the invention, a preferred systemic fungicide may be a succinate dehydrogenase inhibitor fungicide selected from the group consisting of isopyrazam, benzovindiflupyr, mefenoxam, flutolanil, iprodione, fluopyram, mepyramide, carboxin, oxycarboxin, thifluzamide, boscalid and IR9792.
In a preferred embodiment, the third and/or fourth fungicide of the combination of the invention can be selected from an ergosterol biosynthesis inhibitor and/or a quinone outside (Qo) inhibitor, or a mixture thereof.
<xnotran> , , , , , , , , , , , , , , , , , , </xnotran>Metconazole, myclobutanil, penconazole, propiconazole, simeconazole, tebuconazole tetraconazole, triadimefon, triadimenol, triticonazole, prothioconazole, imazalil,
Imidazole, pefurazoate, prochloraz, triflumizole, fenarimol, fluoropyrimidinol, pyribenzoxim, pyricularia
Oxazoles, azinam and mixtures thereof.
In another embodiment, the ergosterol biosynthesis inhibitor may be selected from prothioconazole, tebuconazole, hexaconazole, cyproconazole or epoxiconazole.
<xnotran> , (Qo) , , , , , , , , , , , , , , , , </xnotran>
Pyraclostrobin, fluoxastrobin, fenamidone, pyribencarb and mixtures thereof.
In one embodiment, the extraquinone (Qo) inhibitor fungicide may be selected from azoxystrobin, picoxystrobin, kresoxim-methyl, pyraclostrobin and trifloxystrobin.
In one embodiment of the combination of the invention, the preferred succinate dehydrogenase inhibitor fungicide is isopyrazam.
In one embodiment, the combinations of the present invention include the following preferred combinations.
In the exemplary combinations tabulated below, the term "fungicide a" means at least one of the fungicides selected from the group consisting of: mancozeb (A1), folpet (A2), copper salts such as tribasic copper sulfate (TBCS (A3)), chlorothalonil (A4), or sulfur (A5), which are specifically combined herein with the remaining fungicide.
In the exemplary combinations tabulated below, the term "fungicide B" means at least one of the fungicides selected from the following, and preferably means each of these fungicides alone: isopyrazam (B1), benzovindiflupyr (B2), penthiopyrad (B3), boscalid (B4), IR9792 (thiabendazole amine (B5)), bixafen (B6), fluxapyroxad (B7), furametpyr (B8), penflufen (B9), 3-difluoromethyl-N- (7-fluoro-1,1,3-trimethyl-4-indanyl) -l-methyl-4-pyrazolecarboxamide (B10), cyprodinil (B11), mefenamate (B12), flutolanil (B13), mefenazamide (B14), iprodione (B15), fluopyram (B16), difuramide (B17), carboxin (B18), carboxin (B19), thifluzamide (B20), fluxapyroxafen (B21), iprodione (B22) or boscalid (B23), in particular in combination with the remaining fungicides herein.
In the exemplary combinations tabulated below, the term "fungicide C" means at least one of the fungicides selected from the following, and preferably each of these fungicides alone: cyproconazole (C1), difenoconazole (C2), epoxiconazole (C3), hexaconazole (C4), tebuconazole (C5), tetraconazole (C6), prothioconazole (C7), metalaxyl (C8), metalaxyl-M (C9), benomyl (C10), carbendazim (C11), thiophanate-methyl (C12), zoxamide (C13), fluopicolide (C14), cyazoxystrobin (C15), cyazofamid (C16), ametryn (C17), tricyclazole (C18), ox Sha Puluo (C19) and piccarbazol (C20).
In the exemplary combinations tabulated below, the term "fungicide D" means at least one of the fungicides selected from the following, and preferably each of these fungicides alone: azoxystrobin (D1), picoxystrobin (D2), pyraclostrobin (D3), kresoxim-methyl (D4), trifloxystrobin (D5), cyproconazole (D6), difenoconazole (D7), hexaconazole (D8), epoxiconazole (D9), tebuconazole (D10), tetraconazole (D11), prothioconazole (D12), benomyl (D13), carbendazim (D14), thiophanate-methyl (D15), zoxamide (D16), fluoxafen (D17), cyazoxystrobin (D18), cyazofamid (D19), ametryn (D20), tricyclazole (D21), sha Puluo forest (D22), picrasil (D23), metalaxyl (D24) and metalaxyl (D25).
Accordingly, in one embodiment, the present invention provides a fungicidal combination comprising:
(a) At least one fungicidal combination as described in table 1, lines 1 to 318; and
(b) At least one plant health promoting agent.
Accordingly, in one embodiment, the present invention provides a fungicidal composition comprising:
(a) At least one fungicidal combination as described in table 1, lines 1 to 318;
(b) At least one plant health promoting agent; and
(c) At least one agrochemically acceptable excipient.
Preferred combinations and compositions of the present invention comprise a plant health promoting agent and a fungicidal combination which appears individually in each row in the following table:
TABLE 1：
In one embodiment, exemplary combinations according to the present invention may be selected from the following combinations.
In a preferred embodiment, the preferred fungicide a is mancozeb (A1) and the preferred fungicide B is isopyrazam (B1).
In a preferred embodiment, the preferred fungicide a is mancozeb (A1) and the preferred fungicide B is benzovindiflupyr (B2).
In one embodiment, the preferred fungicide a is mancozeb (A1) and the preferred fungicide B is penthiopyrad (B3).
In one embodiment, the preferred fungicide a is mancozeb (A1) and the preferred fungicide B is boscalid (B4).
In one embodiment, the preferred fungicide a is mancozeb (A1) and the preferred fungicide B is triflumizole (B5).
In one embodiment, the preferred fungicide a is folpet (A2).
In a preferred embodiment, the preferred fungicide a is folpet (A2) and the preferred fungicide B is isopyrazam (B1).
In a preferred embodiment, the preferred fungicide a is folpet (A2) and the preferred fungicide B is benzovindiflupyr (B2).
In one embodiment, the preferred fungicide a is folpet (A2) and the preferred fungicide B is penthiopyrad (B3).
In one embodiment, the preferred fungicide a is folpet (A2) and the preferred fungicide B is boscalid (B4).
In one embodiment, the preferred fungicide a is folpet (A2) and the preferred fungicide B is thiabendazole (B5).
In one embodiment, the preferred fungicide a is folpet (A2) and the preferred fungicide B is boscalid (B23).
In one embodiment, the preferred fungicide a is tribasic copper sulfate (A3).
In a preferred embodiment, the preferred fungicide a is TBCS (A3) and the preferred fungicide B is isopyrazam (B1).
In a preferred embodiment, the preferred fungicide a is TBCS (A3) and the preferred fungicide B is benzovindiflupyr (B2).
In one embodiment, the preferred fungicide a is TBCS (A3) and the preferred fungicide B is penthiopyrad (B3).
In one embodiment, the preferred fungicide a is TBCS (A3) and the preferred fungicide B is boscalid (B4).
In one embodiment, the preferred fungicide a is TBCS (A3) and the preferred fungicide B is thiabendazole (B5).
In one embodiment, the preferred fungicide a is TBCS (A3) and the preferred fungicide B is boscalid (B23).
In one embodiment, the preferred fungicide a is chlorothalonil (A4).
In a preferred embodiment, the preferred fungicide a is chlorothalonil (A4) and the preferred fungicide B is isopyrazam (B1).
In a preferred embodiment, the preferred fungicide a is chlorothalonil (A4) and the preferred fungicide B is benzovindiflupyr (B2).
In one embodiment, the preferred fungicide a is chlorothalonil (A4) and the preferred fungicide B is penthiopyrad (B3).
In one embodiment, the preferred fungicide a is chlorothalonil (A4) and the preferred fungicide B is boscalid (B4).
In one embodiment, the preferred fungicide a is chlorothalonil (A4) and the preferred fungicide B is thiabendazole (B5).
In one embodiment, the preferred fungicide a is chlorothalonil (A4) and the preferred fungicide B is boscalid (B23).
In a preferred embodiment, the preferred fungicide a is sulphur (A5).
In a preferred embodiment, the preferred fungicide a is sulfur (A5) and the preferred fungicide B is isopyrazam (B1).
In a preferred embodiment, the preferred fungicide a is sulphur (A5) and the preferred fungicide B is benzovindiflupyr (B2).
In one embodiment, the preferred fungicide a is sulphur (A5) and the preferred fungicide B is penthiopyrad (B3).
In one embodiment, the preferred fungicide a is sulphur (A5) and the preferred fungicide B is boscalid (B4).
In one embodiment, the preferred fungicide a is sulfur (A5) and the preferred fungicide B is thianaphthenate (B5).
In one embodiment, the preferred fungicide a is sulfur (A5) and the preferred fungicide B is boscalid (B23).
In a preferred embodiment, the preferred fungicide a is mancozeb (A1) or folpet (A2) or tribasic copper sulfate (A3) or chlorothalonil (A4) or sulfur (A5), and the preferred fungicide B is bixafen (B6).
The combination of the invention may be formulated in the form of a composition.
In one embodiment, the present invention can provide a composition comprising:
(a) At least one succinate dehydrogenase inhibitor fungicide;
(b) At least one multi-site fungicide;
(c) At least one plant growth promoter;
(d) At least one other fungicide; and
(e) At least one agrochemically acceptable excipient.
In one embodiment, the succinate dehydrogenase inhibitor fungicide, the multisite fungicide, and the other third fungicide and optionally the fourth fungicide can be selected according to any of the preferred embodiments described above.
In one embodiment, the present invention can provide a composition comprising:
(a) At least one succinate dehydrogenase inhibitor fungicide;
(b) At least one dithiocarbamate fungicide;
(c) At least one other fungicide;
(d) At least one other agrochemically active substance; and
(e) At least one plant growth promoter; and
(f) At least one agrochemically acceptable excipient.
The agrochemical active substance may be selected from herbicides, insecticides, miticides, acaricides, fertilizers, plant growth regulators, biocides, etc.
The amount of the composition according to the invention to be applied will depend on various factors, such as the object of treatment, such as for example a plant, soil or seed; the type of treatment, such as, for example, spraying, dusting, or dressing; the purpose of treatment, such as, for example, prophylactic or therapeutic pest control; in the case of disease control, the type of fungus to be controlled or the application time. The amount of the combination of the invention to be applied can be easily deduced by the skilled agriculturist.
Thus, in one embodiment, the present invention may provide a composition comprising:
(a) At least one pyrazolecarboxamide selected from benzovindiflupyr, bixafen, fluxapyroxad, furametpyr, isopyrazam, penflufen, penthiopyrad and sedaxane;
(b) At least one other fungicide; and
(c) At least one multi-site fungicide;
(d) At least one plant growth promoter; and
the fungicides are combined in agrochemically acceptable amounts.
In one embodiment, the total amount of succinate dehydrogenase inhibitor in the composition may generally range from 0.1 to 99 wt.%, preferably from 0.2 to 90 wt.%. The total amount of dithiocarbamate fungicide in the composition may be in the range of 0.1 to 99 weight percent. The total amount of ergosterol biosynthesis inhibitor in the composition may be in the range of 0.1 to 99 wt%. The total amount of the quinone outside inhibitor in the composition may range from 0.1 to 99% by weight.
In one embodiment, the combined component fungicides of the present invention can be mixed with the dithiocarbamate fungicide, the succinate dehydrogenase inhibitor fungicide and the third fungicide in the ratio of (1-80): (1-80), respectively.
In one embodiment, the components of the composition of the present invention may be mixed in a tank and sprayed at the site of infection, or alternatively mixed with a surfactant and then sprayed.
In one embodiment, the components of the composition of the invention may be used for foliar application, ground application or application of plant propagation material.
In one embodiment, the composition of the invention may be produced generally by: the active substances in the composition are mixed with an inert carrier and, if desired, surfactants and other adjuvants and carriers are added and formulated into solid or liquid formulations, including but not limited to wettable powders, granules, dusts, soluble (liquid) concentrates, suspension concentrates, oil-in-water emulsions, water-in-oil emulsions, emulsifiable concentrates, capsule suspensions, ZC formulations, oil dispersions or other known formulation types. The composition may also be used in the treatment of plant propagation material such as seeds and the like.
Examples of the solid carrier used in the formulation include fine powders or granules such as minerals (such as kaolin, attapulgite clay, bentonite, montmorillonite, acid white clay, pyrophyllite, talc, diatomaceous earth, and calcite), natural organic materials such as corncob powder and walnut shell powder, synthetic organic materials such as urea, salts such as calcium carbonate and ammonium sulfate, synthetic inorganic materials such as synthetic hydrated silica, and aromatic hydrocarbons such as xylene, alkylbenzene, and methylnaphthalene as liquid carriers; alcohols such as 2-propanol, ethylene glycol, propylene glycol and ethylene glycol monoethyl ether; ketones such as acetone, cyclohexanone, and isophorone; vegetable oils such as soybean oil and cottonseed oil; petroleum aliphatic hydrocarbons, esters, dimethyl sulfoxide, acetonitrile and water.
Examples of the surfactant include anionic surfactants such as alkyl sulfate ester salts, alkylaryl sulfonates, dialkyl sulfosuccinates, polyoxyethylene alkylaryl ether phosphate ester salts, lignosulfonates, and naphthalene sulfonate formaldehyde polycondensates; and nonionic surfactants such as polyoxyethylene alkyl aryl ethers, polyoxyethylene alkyl polyoxypropylene block copolymers and sorbitan fatty acid esters; and cationic surfactants such as alkyltrimethylammonium salts.
Examples of other formulation aids include water-soluble polymers such as polyvinyl alcohol and polyvinyl pyrrolidone, polysaccharides such as gum arabic, alginic acid and its salts, CMC (carboxymethyl cellulose), xanthan gum, inorganic materials such as magnesium aluminum silicate and alumina sol, preservatives, coloring agents, and stabilizers such as PAP (isopropyl acid phosphate) and BHT.
The composition according to the invention is effective against the following plant diseases:
diseases of rice: rice blast (Magnaporthe grisea), flax spot (Cochliobolus miyabenus), sheath blight (Rhizoctonia solani), and bakanae disease (Gibberella fujikuroi)).
Wheat diseases: powdery mildew (Erysiphe graminis), gibberellic disease (Fusarium graminearum), fusarium avenaceum (f. Avenaceum), fusarium flavum (f. Culmorum), alternaria leaf spot (Microdochium nivale)), rust disease (Puccinia striiformis), puccinia graminis (p. Graminis), puccinia tritici (p. Recandita)), snowy leaf blight (Micronectriella nivale), sclerotinia snow blight (typhylla sp.) (r. Sphaerica.)) smut (powdery mildew of wheat (Ustilago tritici)), smut (Tilletia graminis), ocular spot (Pseudocercosporella herpotrichoides), leaf blister (Mycosphaera graminicola), leaf blight (Stagonospora nodorum), and yellow leaf spot (Pyrenophora tritici-repentis)).
Barley diseases: powdery mildew (erysiphe graminis), gibberellic disease (fusarium graminearum, fusarium avenanthrae, fusarium flavum, alternaria microsclerotia), rust disease (puccinia striiformis, puccinia graminearum, puccinia hordei (p. Hordei)), loose smut (Ustilago nuda (ustilaba nuda), browning disease (rhynchophyllum lecanii), net blotch (barley net blotch (Pyrenophora teres)), leaf spot (Cochliobolus sativus), leaf stripe disease (barley stripe germs (Pyrenophora gramineae)), and Rhizoctonia solani (Rhizoctonia solani)).
Corn diseases: smut (Ustilago maydis)), brown spot (Cochliobacter heterosporum), cercospora leaf spot (Gloecocospora sorghi)), oriental rust (Puccinia polysora), gray spot (Cercospora zeae-maydis), leukoderma (Phaeosphaera mydis) and/or Pantoea ananatis (Pantoea ananatis), and Rhizoctonia solani (Rhizoctonia solani).
Citrus diseases: melanosis (Diaporthe citri), scab (Elsinoe fawcetti), penicilliosis (Penicillium digitatum), penicillium italicum (p. Italicum), and brown rot (Phytophthora parasitica, phytophthora citri) are known.
Apple diseases: floral blight (Monilinia mali), canker (Valsa ceratosa), powdery mildew (podospora destructor), alternaria leaf spot (Alternaria alternata apple patch), scab (Venturia inaequalis), powdery mildew, bitter rot (Colletotrichum anthracnose), crown rot (phytophthora cactorum), leaf blight (apple brown spot (Diplocarpon mali), and ring rot (Botryosphaeria bereniaca).
Pear diseases: scab (Venturia nashi, venturia pyricularis (v. Pirina)), powdery mildew, melasma (Alternaria alternata brand pear mildew), rust (rust), and phytophthora infestans (phytophthora infestans)).
Peach diseases: brown rot (Monilinia fructicola), powdery mildew, scab (Cladosporium carpophilum), and brown rot (Phomopsis sp.).
Grape diseases: anthracnose (Elsinoe ampelina), mature rot (colletotrichum gloeosporioides), powdery mildew (Uncinula necator), rust (Puccinia ampelina), black rot (Staphylococcus aureus), gray mold, and downy mildew (Plasmopara viticola).
Disease of Japanese persimmon: anthracnose (persimmon Panellum kaki) and leaf spot (persimmon angular leaf spot (Cercospora kaki), persimmon lochia nawae).
Gourd diseases: anthracnose (Colletotrichum lagenarium, cucurbitaceae), powdery mildew (sphacelotheca (Sphaerotheca fuliginea)), gummy stem blight (mycosphaella meloidogenesis), fusarium wilt (Fusarium oxysporum), downy mildew (Pseudoperonospora cubensis), blight (Phytophthora sp.), and rhizoctonia solani (Pythium sp.).
Tomato diseases: early blight (early blight of tomato), leaf mold (Cladosporium fulvum), and late blight (Phytophthora infestans).
Eggplant diseases: brown spot (Phomopsis vexans), and powdery mildew (Erysiphe cichororaceae). Diseases of cruciferous vegetables: alternaria leaf spot (Alternaria japonica), vitiligo (vitiligo chinensis bailii), rhizomatosis (Plasmodiophora brassica), and downy mildew (Peronospora parastica).
Onion diseases: rust (Puccinia allii) and downy mildew (Peronospora destructor).
Soybean diseases: purpura (soybean purpura kikuchi), elsinoe scab (Elsinoe gycins), pod blight (Diaporthe phaseolorum var. Sojae), septoria brown spot (Septoria sojae), gray spot (soybean gray spot pathogen), rust (soybean rust (Phakopsora pachyrhizi), yellow rust, stem rot (Phytophthora sojae), and rhizoctonia solani (rhizoctonia solani).
Bean diseases: anthrax (Colletotrichum lindelmianum). Peanut diseases: leaf spot (Cercospora personata), brown leaf spot (Cercospora arachidicola), and southern blight (sclerotinia rolfsii).
Pea diseases: powdery mildew (pea powdery mildew (Erysiphe pisi)) and root rot (pea root rot (Fusarium solani f.sp.pisi)).
Potato diseases: early blight (Alternaria solani), late blight (Phytophthora infestans), pink rot (rhizoctonia rot (potyphora infestans)), powdery scab of potato (Spongospora subsquens f.sp.suberane).
Strawberry diseases: powdery mildew (Sphaerotheca humuli) and anthracnose (Glomeellae cingulata xiao Cong).
Tea tree diseases: cake disease (Exobasidium reticulatum), celastrus orbiculatus (Elsinoe leucospila), grey blight (Pestalotiopsis sp.), and anthracnose (Colletotrichum the-sine).
Tobacco diseases: brown spot (Alternaria longissima)), powdery mildew (Erysiphe cichororaceae), anthracnose (Colletotrichum tabacum), downy mildew (Peronospora tabacum), and black cavity disease (Phytophthora nicotianae).
Rapeseed diseases: sclerotinia sclerotiorum (Sclerotinia sclerotiorum)) and rhizoctonia damping off (rhizoctonia solani). Cotton diseases: rhizoctonia solani (rhizoctonia solani).
Beet diseases: cercospora leaf spot (Cercospora betanae), leaf blight (rhizoctonia solani), root rot (rhizoctonia solani), and rhizopus root rot (aphanophora cocurrentis).
Diseases of roses: black spot (rosebush (Diplocarpon rosae)), powdery mildew (rosebush (sphaeraceae pannosa)), and downy mildew (rosewood mildew). Diseases of chrysanthemum and asteraceae plants: downy mildew (Bremia lactucae), leaf blight (Septoria chrysosporium-indici), and white rust (Horikoshi Horiki).
Various group diseases: diseases caused by Pythium species (Pythium spp), debar Li Fumei (Pythium debarynum), pythium graminearum (Pythium graminicola), pythium irregulare (Pythium irregularium), pythium ultimum (Pythium ultimum), botrytis cinerea (Botrytis cinerea), and Sclerotinia sclerotiorum (Sclerotinia sclerotiorum).
Disease of Japanese radish: alternaria leaf spot (Alternaria brassicae (Alternaria brassicola)).
Lawn diseases: spot (silver blotch (sclerotiotinia homococcpa)), brown spot, and megaspot (rhizoctonia solani).
Banana diseases: black sigatoka (Mycosphaerella filensis), sigatoka (Mycosphaerella fulva) and sigatoka (Mycosphaerella lutea).
Sunflower diseases: downy mildew (downy mildew of sunflower (Plasmopara halstedii)).
Seed diseases or diseases in the early stages of the growth of various plants are caused by Aspergillus (Aspergillus spp.), penicillium (Penicillium spp.), fusarium (Fusarium spp.), gibberella (Gibberella spp.), trichoderma (Tricoderma spp.), rhizopus (Thielavisopsis spp.), rhizopus (Rhizopus spp.), mucor (Mucor spp.), coriolus (Corticium spp.), phoma (Phoma spp.), rhizoctonia (Rhizoctonia spp.), or Diospora (Diplodia spp.).
Viral diseases of various plants mediated by polymyxa (Polymixa spp.) or oleander spp.
The composition of the present invention can be used for agricultural lands such as fields, paddy fields, lawns and orchards, or for non-agricultural lands. The invention can be used for controlling diseases in agricultural lands to cultivate plants without any phytotoxicity to the plants.
Examples of crops for which the compositions of the present invention may be used include, but are not limited to, corn, rice, wheat, barley, rye, oats, sorghum, cotton, soybean, peanut, buckwheat, sugar beet, rapeseed, sunflower, sugarcane, tobacco, and the like; vegetable: solanaceous vegetables such as eggplant, tomato, sweet pepper, potato, etc., cucurbitaceous vegetables such as cucumber, pumpkin, zucchini, watermelon, melon, pumpkin, etc., cruciferous vegetables such as radish, white radish, horseradish, cabbage, chinese cabbage, mustard, broccoli, cauliflower, etc., asteraceous vegetables such as burdock, garland chrysanthemum, artichoke, lettuce, etc., liliaceous vegetables such as green onion, garlic and asparagus, starchy vegetables such as carrot, parsley, celery, parsnip, etc., chenopodiaceae vegetables such as spinach, swiss chard, etc., menthaceae vegetables such as perilla leaf, mint, basil, etc., strawberry, sweet potato, japanese yam, taro, etc., flower, foliage plant, lawn grass, fruit: pome fruits such as apple, pear, citrus and the like, stone fruits such as peach, plum, nectarine, dark plum, cherry tomato, apricot, prune and the like, citrus fruits such as orange, lemon, lime, grapefruit and the like, nuts such as chestnut, walnut, hazelnut, almond, pistachio, cashew, macadamia and the like, berries such as blueberry, cranberry, blackberry, raspberry and the like, grapes, persimmon, olive, plum, banana, coffee, date palm, coconut and the like, trees other than fruit trees, tea, mulberry, flowering plants, trees such as ash, birch, dogwood, eucalyptus, ginkgo, clove, maple, oak, poplar, nakai-star, sweetgum, syzygium, zelkova, thuja, fir, hemlock, juniper, pine, spruce, yew and the like.
In one embodiment, the component fungicides of the combinations of the present invention may be mixed in the ratio of (1-80) to (1-80), respectively.
In one aspect, the present invention may provide a method of controlling fungal diseases, the method comprising applying a combination comprising:
(a) At least one succinate dehydrogenase inhibitor fungicide;
(b) At least one plant growth promoter;
(c) At least one other fungicide; and
(d) At least one multi-site fungicide.
In one embodiment, the succinate dehydrogenase inhibitor fungicide, the quinone outside inhibitor fungicide, the ergosterol biosynthesis inhibitor fungicide, and the dithiocarbamate fungicide can be selected according to any of the preferred embodiments of the combinations described above.
The combination of the present invention may be sold as a pre-mix composition or kit of parts such that the individual actives may be mixed prior to spraying. Alternatively, the kit-of-parts may comprise a succinate dehydrogenase inhibitor fungicide and a dithiocarbamate fungicide premixed and the third active may be mixed with an adjuvant such that the two components may be mixed in a canister prior to spraying.
The compositions of the present invention may be applied simultaneously as a canned mixture or formulation, or may be applied sequentially. The soil may be applied before emergence of the plants (before or after planting). The application may be carried out as foliar sprays at various times during the development of the crop, and may be applied once or twice in the morning and evening after emergence.
The composition according to the invention may be applied before or after the available plants or propagation material thereof have been infected with fungi.
As will be demonstrated in the examples, the addition of a plant growth promoter to a combination of dithiocarbamate fungicides and a combination of succinate dehydrogenase inhibitors (which are combined with an extraquinone inhibitor and/or an ergosterol biosynthesis inhibitor) greatly improves disease control and improves yield and demonstrates a synergistic effect. The lower the performance of the mixture in disease control, the greater the additional beneficial effect of mancozeb when added to the composition of the invention.
In one embodiment, the combination of the invention comprises, in addition to the multi-site contact fungicide and the plant growth promoting agent, at least one benzimidazole fungicide selected from albendazole, benomyl, carbendazim, chlorofenazole, cyhalonil, imicarb, fuberidazole, mefenbendazole, imazalil and thiabendazole.
In one embodiment, the benzimidazole fungicide is carbendazim.
In one embodiment, the benzimidazole fungicide is benomyl.
In one embodiment, the dithiocarbamate fungicide may be selected from the group consisting of amobam, arsenic disulfide, thiram oxide, mycoparb, thiabendazole, copper oxychloride, disulfiram, ferbam, metam, sodium metiram, thiram, arsine, ziram, dazomet, thion, metiram, mancopper, mancozeb, maneb, metiram, polycarbamate, zineb and zineb.
In one embodiment, the dithiocarbamate fungicide is selected from mancozeb.
In one embodiment, the combination of the invention may comprise at least a third fungicide or insecticide in addition to the multisite fungicide.
In one embodiment, the third fungicide is a combination of at least two or more fungicides. In this embodiment, these fungicides are referred to herein as a third fungicide and a fourth fungicide, respectively. However, the third and fourth fungicides are preferably different fungicides, but they may be a combination of two fungicides from the same class of fungicides.
In one embodiment, the combination of the invention may additionally comprise other plant health promoting additives, such as fertilizers, micronutrients, biological additives, and the like, which are known to enhance the growth and health of plants.
In one embodiment of the combination of the invention, the preferred dithiocarbamate fungicide is mancozeb, and the preferred benzimidazole fungicide is carbendazim, and the plant health additive is stabilised orthosilicic acid.
In one embodiment of the combination of the invention, the preferred dithiocarbamate fungicide is mancozeb, and the preferred strobilurin fungicide is azoxystrobin, and the plant health additive is stabilised orthosilicic acid.
The combination of the invention may be formulated in the form of a composition.
In one embodiment, the present invention can provide a composition comprising:
(a) At least one dithiocarbamate fungicide;
(b) At least one benzimidazole fungicide;
(c) At least one silicic acid-based plant health promoting additive; and
(d) At least one agrochemically acceptable excipient.
In one embodiment, the present invention can provide a composition comprising:
(a) At least one dithiocarbamate fungicide;
(b) At least one benzimidazole fungicide;
(c) At least one silicic acid-based plant health promoting additive;
(d) At least one other fungicide or insecticide; and
(e) At least one agrochemically acceptable excipient.
In one embodiment, the present invention can provide a composition comprising:
(a) At least one dithiocarbamate fungicide;
(b) At least one benzimidazole fungicide;
(c) At least one silicic acid-based plant health promoting additive;
(d) At least one further health-promoting additive selected from the group consisting of fertilizers, micronutrients, mycorrhiza, biological additives to enhance plant growth; and
(e) At least one agrochemically acceptable excipient.
The amount of the composition according to the invention to be applied will depend on various factors, such as the object of treatment, such as for example a plant, soil or seed; the type of treatment, such as, for example, spraying, dusting, or dressing; the purpose of treatment, such as, for example, prophylactic or therapeutic pest control; in the case of disease control, the type of fungus to be controlled or the application time. The amount of the combination of the invention to be applied can be easily deduced by the skilled agriculturist.
Thus, in one embodiment, the present invention may provide a composition comprising:
(a) Mancozeb;
(b) Carbendazim; and
(c) A stable orthosilicic acid.
In one embodiment, the present invention can provide a composition comprising:
(a) Mancozeb;
(b) Carbendazim;
(c) A stable orthosilicic acid; and
(d) At least one agrochemically acceptable excipient.
In one embodiment, the total amount of dithiocarbamate fungicide in the composition may generally range from 0.1 to 99 weight percent, preferably from 0.2 to 90 weight percent. The total amount of benzimidazole fungicide in the composition may range from 0.1 to 99 wt%. The total amount of the plant health promoting additives in the composition based on silicic acid may be in the range of 0.1 to 99 wt%. The total amount of the third fungicide/insecticide/plant growth additive in the composition may be in the range of 0.1 to 99 wt%.
In one embodiment, the components of the combination of the present invention may be mixed in a ratio of (1-80): (1-80) dithiocarbamate fungicide, benzimidazole fungicide and silicic acid based plant health additive, respectively.
In one embodiment, the components of the composition of the present invention may be mixed in a tank and sprayed at the site of infection, or alternatively mixed with a surfactant and then sprayed.
In one embodiment, the components of the composition of the invention may be used for foliar application, ground application or application of plant propagation material.
In one embodiment, the composition of the invention may be produced generally by: the active substances in the composition are mixed with an inert carrier and, if desired, surfactants and other adjuvants and carriers are added and formulated into solid or liquid formulations, including but not limited to wettable powders, granules, dusts, soluble (liquid) concentrates, suspension concentrates, oil-in-water emulsions, water-in-oil emulsions, emulsifiable concentrates, capsule suspensions, ZC formulations, oil dispersions or other known formulation types. The composition may also be used for the treatment of plant propagation material such as seeds and the like.
In one aspect, the invention can provide a method of controlling fungal pests at a locus and promoting plant health, the method comprising applying a combination comprising:
(a) At least one dithiocarbamate fungicide;
(b) At least one benzimidazole fungicide; and
(c) At least one silicic acid-based plant health promoting additive.
In one embodiment, the dithiocarbamate fungicide, the benzimidazole fungicide and the silicic acid-based plant health promoting additive may be selected according to any one of the preferred embodiments of the combinations described above.
In one aspect, the combination of the invention is useful for promoting plant health, the method comprising applying a combination of:
(a) At least one dithiocarbamate fungicide;
(b) At least one benzimidazole fungicide; and
(c) At least one silicic acid-based plant health promoting additive.
In one embodiment, the dithiocarbamate fungicide, the benzimidazole fungicide and the silicic acid-based plant health promoting additive may be selected according to any one of the preferred embodiments of the combinations described above.
The combination of the present invention may be sold as a pre-mix composition or kit of parts such that the individual actives may be mixed prior to spraying. Alternatively, the kit-of-parts may comprise a pre-mixed dithiocarbamate fungicide and second and/or third fungicide, and the benzimidazole fungicide may be mixed with a separately packaged adjuvant and silicic acid-based plant health additive, such that the three components may be mixed in a can prior to spraying.
The control method of the present invention can be carried out by spraying the proposed pot mix or the individual fungicides can be formulated as a kit of parts containing the various components which can be mixed as indicated before spraying.
In one embodiment, the present invention provides a kit-of-parts comprising a plurality of components, wherein the plurality of components comprises:
(a) At least a first component comprising at least one dithiocarbamate fungicide;
(b) At least a second component comprising at least one benzimidazole fungicide; and
(c) At least a third component comprising at least a silicic acid-based plant health promoting additive.
In one embodiment, the present invention provides a kit-of-parts comprising a plurality of components, wherein the plurality of components comprises:
(a) At least a first component comprising at least one dithiocarbamate fungicide;
(b) At least a second component comprising at least one strobilurin fungicide; and
(c) At least a third component comprising at least a silicic acid-based plant health promoting additive.
In one embodiment, the kit of parts comprises an instruction manual comprising instructions directing the user to mix the components prior to use.
In one embodiment, the components of the present invention may be packaged such that the dithiocarbamate fungicide, the benzimidazole fungicide and the silicic acid-based plant health promoting additive may be packaged separately and then mixed in a can prior to spraying.
In another embodiment, the components of the present invention may be packaged such that the dithiocarbamate fungicide, the benzimidazole fungicide and the silicic acid-based plant health promoting additive may be packaged separately, while the other additives are packaged separately such that the two components may be mixed in a can at the time of spraying.
In another embodiment, the components of the present invention may be packaged as a composition such that the dithiocarbamate fungicide, the benzimidazole fungicide and the silicic acid-based plant health promoting additive are formulated into one composition, and the other additives are separately packaged such that the two components may be mixed in a can at the time of spraying.
Surprisingly, the present inventors have found that the dithiocarbamate fungicides, benzimidazole fungicides and silicic acid-based plant health promoting additives of the present invention are not effective for fungal control when applied alone, but exhibit excellent synergistic control when applied together. The combination controls fungi both pre-and post-emergence. As will be demonstrated by the examples, the combination of dithiocarbamate fungicides, benzimidazole fungicides, and silicic acid-based plant health promoting additives synergistically controls fungi at a locus. The present invention thus provides an advantageous method for controlling fungi.
The compositions of the present invention may be applied simultaneously as a canned mixture or formulation, or may be applied sequentially. The application may be carried out as foliar sprays at various times during the development of the crop, and may be applied once or twice in the morning and evening after emergence.
The composition according to the invention may be applied before or after the available plants or propagation material thereof have been infected with fungi.
As demonstrated, the addition of a silicic acid-based plant health promoting additive to a combination of a dithiocarbamate fungicide and a benzimidazole fungicide greatly improved disease control as well as increased yield and demonstrated synergistic effects. The lower the performance of the mixture in disease control, the greater the additional benefit of the silicic acid-based plant health promoting additive when added to the composition of the present invention.
Detailed Description
In one embodiment, the exemplary compositions or formulations are prepared by known or recognized methods, for example, by uniformly mixing and grinding the active ingredient with the bulking agent (e.g., solid carrier, etc.). The solid carrier used is usually a natural mineral filler, such as china clay. Sodium lignosulfonate and citric acid may also be added to the formulation if desired.
Example 1：
Thus, in an exemplary embodiment, the present invention provides a composition comprising:
(a) Mancozeb in an amount of about 10.4%;
(b) Carbendazim in an amount of about 2.00%;
(c) Silicic acid in an amount of about 1.30%; and
(d) Clay in an amount of about 84.5%.
In exemplary embodiments, the present invention provides a composition comprising:
(a) Mancozeb in an amount of about 12.1% with a purity of about 86%;
(b) Carbendazim in an amount of about 2.00%;
(c) Silicic acid in an amount of about 1.30%; and
(d) Clay in an amount of about 84.5%.
Example 2：
Another composition was prepared in a similar manner with the following ingredients:
thus, in an exemplary embodiment, the present invention provides a composition comprising:
(a) Mancozeb in an amount of about 10.4%;
(b) Carbendazim in an amount of about 2.00%;
(c) Silicic acid in an amount of about 1.30%;
(d) Sodium lignosulfonate in an amount of about 2.0%; and
(e) Clay in an amount of about 84.5%.
In exemplary embodiments, the present invention provides a composition comprising:
(a) Mancozeb in an amount of about 12.1% with a purity of about 86%;
(b) Carbendazim in an amount of about 2.00%;
(c) Silicic acid in an amount of about 1.30%;
(d) Sodium lignosulfonate in an amount of about 2.0%; and
(e) Clay in an amount of about 84.5%.
Thus, in an exemplary embodiment, the present invention provides a composition comprising:
(a) Mancozeb in an amount of about 10.4%;
(b) Carbendazim in an amount of about 2.00%;
(c) Silicic acid in an amount of about 1.30%;
(d) Citric acid in an amount of about 0.10%;
(e) Sodium lignosulfonate in an amount of about 2.0%; and
(f) Clay in an amount of about 84.5%.
In exemplary embodiments, the present invention provides a composition comprising:
(a) Mancozeb in an amount of about 12.1% with a purity of about 86%;
(b) Carbendazim in an amount of about 2.00%;
(c) Silicic acid in an amount of about 1.30%;
(d) Citric acid in an amount of about 0.10%;
(e) Sodium lignosulfonate in an amount of about 2.0%; and
(f) Clay in an amount of about 84.5%.
Comparative test：
A comparative test of the combination according to the invention was carried out and compared with a test composition prepared without the silicic acid plant health promoting agent of the invention. Comparative performance of the compositions of the present invention was observed in terms of plant growth enhancement benefits and efficacy against She Daowen, stemborer, leaf roller and BPH.
At pretreatment, 10, 14, 28 and 42 days post-application, the percentage of disease (She Daowen) severity was observed from 20 randomly selected hills. The incidence of stemborers/leaf rollers/BPH was also observed in the test fields. Plant height, root length and greenness were also measured from 20 randomly selected hills 14, 28 days after application, and tiller number was measured 28, 42 and 60 days after application. The number of tillers produced from 20 randomly selected hills was counted and the yield per plot (in Kg) at harvest was recorded.
Test 1: mean plant height was observed on 40 DAA-5 hills: crop-rice variety ASD16
Test 2: average plant height values observed on 28 DAA-5 hills
Experiment 3-Observation of mean plant height on 28 DAA-5 hills
Test 4-Observation of mean plant height on 28 DAA-5 hills
Total average of four trials：
Test 2：
A second test was conducted to evaluate the efficacy of mancozeb and orthosilicic acid as a pot mix application against tomato early blight and fruit borers. The following treatments were used for this test:
these experiments were conducted on tomato variety TO-1389 for fruit borers and early blight. In black soil type fields, the cell size is 5 × 3sq m. The experiment was designed as a randomized block design with 3 replicates. The field is irrigated with rain water by drip irrigation. A backpack-type electric sprayer having a hollow conical nozzle is used. The amount of water used for dilution was 500L/ha. Tomato plants were transplanted at 6 months and 13 days, while the first, second and third sprays of the corresponding treatments were performed at 8 months and 8 days, 8 months and 18 days, and 8 months and 29 days, respectively. It was observed that all treated crops showed phytotoxicity of 0%.
A-10: 10 days after the first spraying; b-10: 10 days after the 2 nd spraying; c-10: 10 days after the 3 rd spray.
Thus, it was found that none of the tested products showed any symptoms of crop injury. It is found that the Mancozeb + OSA under 2000+750g/ha shows a synergistic effect on the early blight, the disease control rate is 79.82%, and the yield is 39.93tons/ha.
It was therefore concluded that the presence of a plant growth promoter according to the invention (such as silicic acid) resulted in a surprising increase in plant height, root length and tiller number of the paddy crop in four observed trials.
While the foregoing written description of the invention enables one of ordinary skill to make and use what is presently considered to be the best mode thereof, those of ordinary skill will understand and appreciate the existence of variations, combinations, and equivalents of the specific embodiments, methods, and examples herein. Accordingly, the present invention should not be limited by the above-described embodiments, methods and examples, but by all embodiments and methods within the scope and spirit of the present invention.
Claims (10)
1. A combination, comprising: at least one multi-site contact fungicide and at least one plant health promoting agent.
2. The combination according to claim 1, additionally comprising at least one systemic fungicide.
3. A combination according to claim 1 or claim 2, wherein the multi-site contact fungicide is:
(a) A dithiocarbamate fungicide selected from the group consisting of amobam, arsonium, thiram oxide, morbus, thiabendazole, copper thiram, disulfiram, ferbam, metam, sodium metiram, thiram, arsine, ziram, dazomet, thioneb, metiram, mancopper, mancozeb, maneb, metiram, polycarbamate, zineb and zineb;
(b) A phthalimide fungicide selected from captan, captafol, and folpet; or
(c) Chlorothalonil; or
(d) A sulfonamide fungicide selected from dichlofluanid and tolylfluanid; or
(e) A biguanide fungicide selected from the group consisting of iminoctadine and iminoctadine; or
(f) A triazine fungicide selected from the group consisting of trichlofop; or
(g) Quinone fungicides selected from dithianon; or
(h) Quinoxaline fungicides selected from the group consisting of imazamox and tetrachloroquine
(ii) a quinoline; or
(i) A dicarboxamide fungicide selected from the group consisting of carfentrazone-ethyl; or
(j) Inorganic fungicide selected from copper fungicides including copper (II) hydroxide, copper oxychloride, copper (II) sulfate, basic copper sulfate, bordeaux mixture, copper salicylate C 7 H 4 O 3 * Cu, cuprous oxide CU 2 O; or sulfur.
4. A combination according to any one of the preceding claims, wherein the plant growth promoter is a silicic acid based additive having the general formula:
[SiO x (OH) 4-2x ] n 。
5. the combination according to any one of the preceding claims, wherein the plant growth promoter is a silicic acid-based additive selected from the group consisting of metasilicic acid (H) 2 SiO 3 ) Ortho silicic acid (H) 4 SiO 4 ) Disilicic acid (H) 2 Si 2 O 5 ) And pyrosilicic acid (H) 6 Si 2 O 7 )。
6. The combination according to any one of the preceding claims, wherein the systemic fungicide is:
(a) Succinate dehydrogenase inhibitors selected from the group consisting of benzovindiflupyr, bixafen, fluxapyroxad, furametpyr, isopyrazam, penflufen, penthiopyrad, 3-difluoromethyl-N- (7-fluoro-1,1,3-trimethyl-4-indanyl) -l-methyl-4-pyrazolecarboxamide, epoxiconazole, mebutamol, flutolanil, mebutamol, carboxin, oxycarboxin, thifluzamide, fluxapyroxad; iprodione and boscalid; or
(b) A nucleic acid synthesis inhibitor fungicide selected from an acylalanine such as benalaxyl, benalaxyl-m, furalaxyl, metalaxyl-m,
oxazolidinones such asSuch as
Shuangling, butyrolactone such as methylfuroamide, hydroxy- (2-amino-) pyrimidines such as butylpyrimidine sulfonate, dimetrimol, ethirimol, iso-pyrimindine
Azoles such as hydroxymethyl
Azoles, isothiazolinones such as Xin Saitong, carboxylic acids such as
A quinate;
(c) Cytoskeletal and motor protein inhibitors selected from benzimidazoles such as benomyl, carbendazim, fuberidazole, thiabendazole; thiophanate such as thiophanate, thiophanate-methyl; n-phenyl carbamates such as diethofencarb; toluamides such as zoxamide; thiazolecarboxamides such as ethaboxam; phenylureas such as pencycuron, benzamides such as fluopicolide; cyanoacrylates such as phenamacril;
(d) A respiratory process inhibitor fungicide selected from the group consisting of pyrimidinamines such as difluoroforest; <xnotran> -5- , , , , , , , , , , , , , , , , </xnotran>
Pyraclostrobin, fluoxastrobin, fenamidone, pyribencarb and mixtures thereof;
oxazolidinediones such as
Famoxadone; imidazolinones such as fenamidone; benzyl carbamates such as pyribencarb; n-methoxy- (phenyl-ethyl) -pyrazole-carboxamides such as pyrimidinamines such as difluoroforest; cyanoimidazoles such as cyazofamid; sulfamoyl triazoles such as anmeisu; dinitrophenyl crotonates such as binapacryl, dinotefuran, dinocap; 2,6-dinitroanilines such as fluazinam; pyrazolones such as pyrimidinehydrazone; triphenyltin compounds such as stannic distemper, triphenyltin chloride, fentin chloride; thiophenecarboxamides such as silthiopham; triazolopyrimidinamines such as ametoctradin;
(e) Amino acid and protein synthesis inhibitor fungicides selected from anilinopyrimidines such as cyprodinil, mepanipyrim, pyrimethanil, antibiotic fungicides such as blasticidin-S, kasugamycin, streptomycin, oxytetracycline, and the like;
(f) A signal transduction inhibitor fungicide selected from aryloxyquine such as quinoxyfen; quinazolinones such as propoxymoline; phenylpyrroles such as fenpiclonil, fludioxonil; dicarboximides such as ethidium, dimethachlon, iprodione, procymidone, and vinclozolin;
(g) Lipid synthesis and membrane integrity disruptors, such as phosphorothioates such as diphenoxylate, iprobenfos, mepiquat chloride; dithianes such as isoprothiolane; aromatic hydrocarbons such as biphenyl, dicyclopentadienyl, chloronitroamine, pentachloronitrobenzene (PCNB), tetraoxynitrobenzene (TCNB), tolclofos-methyl, and the like; 1,2,4-thiadiazoles such as hymexazol; carbamates such as iodopropynyl butylmethylamine acid ester, propamocarb, thiocarb and the like;
(h) Sterol biosynthesis inhibitors selected from triazoles such as azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, metconazole, myclobutanil, penconazole, propiconazole, simeconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triticonazole, prothioconazole, piperazines such as trifenazole; pyridines such as pyribenzoxim, pyribenzoxim
Azole; pyrimidines such as chloropyrimidinol, fluoropyrimidinol imidazoles such as imazalil,
Imidazole, pefurazoate, prochloraz, triflumizole; morpholines such as dimethylmorpholine, moroxydine, fenpropimorph, tridemorph, and the like; piperidines such as fenpropidin, propaquin; spirocuprammones such as spiroxamine; amides such as fenhexamid; aminopyrazolinones such as fenpyrazamine; thiocarbamates such as barnyard grass; propionamides such as naftifine, terbinafine and mixtures thereof;
(i) A cell wall biosynthesis inhibitor fungicide selected from peptidyl pyrimidine nucleoside fungicides such as polyoxins, cinnamamides such as dimethomorph, flumorph, pyrimorph; valinamide carbamates such as benthiavalicarb, propineb, validamide; mandelic acid amides such as mandipropamid and mixtures thereof;
(j) A melanin synthesis inhibitor fungicide selected from isobenzofuranones such as tetrachlorophthalide; pyrroloquinolinones such as pyrroloquinolone; triazolobenzothiazoles such as tricyclazole; cyclopropanecarboxamides such as cyclopropylamide; amides such as diclorocyanid; propionamides such as fenpyrad; trifluoroethyl carbamates such as topu Luo Ka; and mixtures thereof;
(k) A host plant defense inducer fungicide selected from benzothiadiazoles such as acibenzolar-S-methyl; benzisothiazoles such as thiabendazole; thiadiazole carboxamides such as tiadinil, isotianil; polysaccharides such as laminarin; and mixtures thereof; or
(l) An additional third or fourth fungicide selected from cyanoacetamide oximes such as cymoxanil; ethyl phosphonates such as fosetyl aluminum, phosphoric acid and salts thereof; anthranilic acids such as cumylphthalide; benzotriazines such as imidazoxazines; benzene sulfonamides such as flusulfamide; pyridazinones such as pyridaben; thiocarbamates such as sulbencarb; phenyl acetamides such as cyflufenamid; aryl phenyl ketones such as metrafenone, methoxybenzene cry bacteria; guanidines such asDetermining the number of fruits; cyanomethylene thiazolidinediones such as fluanib; pyrimidinone hydrazones such as cyprodinil; piperidinyl thiazole isomers
Oxazolines such as o Sha Puluo forest; 4-quinolinylacetic acid esters such as terbinafine; tetrazolium ketoximes such as picazole; glucopyranosyl antibiotics such as validamycin; fungicides such as mineral oil, organic oil, potassium bicarbonate and mixtures thereof;
<xnotran> (m) , , , , , , , , , , , , , , , , , , , , , , , , , , , , </xnotran>
Imidazole, pefurazoate, prochloraz, triflumizole, fenarimol, fluoropyrimidinol, pyribenzoxim, pyricularia
Oxazoles, azinam and mixtures thereof;
<xnotran> (n) (Qo) , , , , , , , , , , , , , , , , </xnotran>
Pyraclostrobin, fluoxastrobin, fenamidone, pyribencarb and mixtures thereof; or
(o) a fungicide selected from isopyrazam (B1), benzovindiflupyr (B2), penthiopyrad (B3), boscalid (B4), IR9792 (fluoroindacamide (B5)), bixafen (B6), fluxapyroxad (B7), furametpyr (B8), penflufen (B9), 3-difluoromethyl-N- (7-fluoro-1,1,3-trimethyl-4-indanyl) -l-methyl-4-pyrazolecarboxamide (B10), epoxiconazole (B11), meclofen (B12), flutolanil (B13), mefenamide (B14), iprothiamine (B15), fluopyram (B16), methylfuroamide (B17), carboxin (B18), carboxin (B19), thifluzamide (B20), fluxapyroxafen (B21); benthiavalicarb isopropyl (B22) or boscalid (B23); or
(p) a fungicide selected from the group consisting of cyproconazole (C1), difenoconazole (C2), epoxiconazole (C3), hexaconazole (C4), tebuconazole (C5), tetraconazole (C6), prothioconazole (C7), metalaxyl (C8), metalaxyl-M (C9), benomyl (C10), carbendazim (C11), thiophanate-methyl (C12), zoxamide (C13), fluopicolide (C14), cyazoxystrobin (C15), cyazofamid (C16), ametryn (C17), tricyclazole (C18), oxflatf Sha Puluo forest (C19) and picrass (C20); or
(q) a fungicide selected from azoxystrobin (D1), picoxystrobin (D2), pyraclostrobin (D3), kresoxim-methyl (D4), trifloxystrobin (D5), cyproconazole (D6), difenoconazole (D7), hexaconazole (D8), epoxiconazole (D9), tebuconazole (D10), tetraconazole (D11), prothioconazole (D12), benomyl (D13), carbendazim (D14), thiophanate-methyl (D15), zoxamide (D16), fluoxastrobin (D17), cyazoxystrobin (D18), cyazofamid (D19), ametryn (D20), tricyclazole (D21), ox Sha Puluo forest (D22), picrasol (D23), metalaxyl (D24) and mefenoxam (D25); or
(r) at least one fungicidal combination as described in table 1, lines 1 to 318.
7. A composition comprising the fungicidal combination according to any one of claims 1 to 6, together with at least one agrochemically acceptable excipient.
8. A method of controlling fungal diseases comprising applying a combination according to claims 1-6 or a composition according to claim 7.
9. A kit-of-parts comprising a plurality of components, wherein the plurality of components comprises:
(a) At least a first component comprising at least one dithiocarbamate fungicide;
(b) At least a second component comprising at least one systemic fungicide; and
(c) At least a third component comprising at least a silicic acid-based plant health promoting additive.
10. The kit-of-parts according to claim 10, wherein the dithiocarbamate fungicide is mancozeb and the systemic fungicide is a benzimidazole fungicide, or a strobilurin fungicide, or a conazole fungicide, or a succinate dehydrogenase inhibitor fungicide.
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| IN201731036884 | 2017-10-17 | ||
| IN201731036884 | 2017-10-17 | ||
| CN201880074490.6A CN111683531A (en) | 2017-10-17 | 2018-10-13 | Novel agrochemical combinations |
| PCT/IB2018/057950 WO2019077460A1 (en) | 2017-10-17 | 2018-10-13 | Novel agrochemical combinations |
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| MX (1) | MX2020004846A (en) |
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| AU2019418147A1 (en) * | 2018-12-31 | 2021-08-12 | Adama Makhteshim Ltd. | Fungicidal mixture |
| TW202400021A (en) | 2019-07-25 | 2024-01-01 | 印度商Ｕｐｌ有限公司 | Novel agrochemical combinations |
| CN114401634A (en) * | 2019-09-28 | 2022-04-26 | Upl有限公司 | Treatment of black sigatoka |
| FR3124925A1 (en) * | 2021-07-08 | 2023-01-13 | Qiuhua Huang | An use of bacterial composition |
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|---|---|---|---|---|
| US3127311A (en) * | 1959-03-10 | 1964-03-31 | Fungicidal compositions | |
| CN87100159A (en) * | 1986-01-13 | 1987-09-16 | 纳特曼和希依有限公司 | The application of film regulatory factor and contain the product of this film regulatory factor |
| CN88102052A (en) * | 1987-03-09 | 1988-09-21 | 奇诺英药物化学工厂有限公司 | Bactericide composition |
| CN1652687A (en) * | 2002-03-20 | 2005-08-10 | 生物矿物股份有限公司 | Choline-silicic acid complex with osmolytes and divalent trace elements |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9078465B2 (en) * | 2002-03-20 | 2015-07-14 | Bio Minerals N.V. | Choline-silicic acid complex with osmolytes and divalent trace elements |
| ITMI20051558A1 (en) * | 2005-08-09 | 2007-02-10 | Isagro Spa | MIXTURES E-O SYNERGIC COMPOSITIONS CIN HIGH ACTIVITY FEATURES |
| CN106386137A (en) * | 2016-09-22 | 2017-02-15 | 程世忠 | A method of sweet potato interplanting under deciduous trees |
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2018
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- 2018-10-13 CN CN202211120851.0A patent/CN115530175A/en active Pending
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3127311A (en) * | 1959-03-10 | 1964-03-31 | Fungicidal compositions | |
| CN87100159A (en) * | 1986-01-13 | 1987-09-16 | 纳特曼和希依有限公司 | The application of film regulatory factor and contain the product of this film regulatory factor |
| CN88102052A (en) * | 1987-03-09 | 1988-09-21 | 奇诺英药物化学工厂有限公司 | Bactericide composition |
| WO1988006841A1 (en) * | 1987-03-09 | 1988-09-22 | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. | Fungicide compositions |
| CN1652687A (en) * | 2002-03-20 | 2005-08-10 | 生物矿物股份有限公司 | Choline-silicic acid complex with osmolytes and divalent trace elements |
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| WO2019077460A1 (en) | 2019-04-25 |
| CN111683531A (en) | 2020-09-18 |
| MX2020004846A (en) | 2020-08-13 |
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