TW201625658A - 經取代之核苷、核苷酸及其類似物 - Google Patents

經取代之核苷、核苷酸及其類似物 Download PDF

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Publication number
TW201625658A
TW201625658A TW104142822A TW104142822A TW201625658A TW 201625658 A TW201625658 A TW 201625658A TW 104142822 A TW104142822 A TW 104142822A TW 104142822 A TW104142822 A TW 104142822A TW 201625658 A TW201625658 A TW 201625658A
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TW
Taiwan
Prior art keywords
optionally substituted
compound
group
alkyl
echovirus
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TW104142822A
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English (en)
Chinese (zh)
Inventor
廣義 王
大衛 柏娜德 史密斯
里歐尼德 畢吉爾曼
克莉絲汀安 安卓斯 傑可爾
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艾洛斯生物製藥公司
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Publication of TW201625658A publication Critical patent/TW201625658A/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/10Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
TW104142822A 2014-12-19 2015-12-18 經取代之核苷、核苷酸及其類似物 TW201625658A (zh)

Applications Claiming Priority (1)

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US201462094418P 2014-12-19 2014-12-19

Publications (1)

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TW201625658A true TW201625658A (zh) 2016-07-16

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TW104142822A TW201625658A (zh) 2014-12-19 2015-12-18 經取代之核苷、核苷酸及其類似物

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US (2) US9890188B2 (cg-RX-API-DMAC7.html)
EP (1) EP3233879A4 (cg-RX-API-DMAC7.html)
JP (1) JP2017538722A (cg-RX-API-DMAC7.html)
CN (1) CN107250145A (cg-RX-API-DMAC7.html)
AU (1) AU2015364630A1 (cg-RX-API-DMAC7.html)
CA (1) CA2970936A1 (cg-RX-API-DMAC7.html)
HK (1) HK1245800A1 (cg-RX-API-DMAC7.html)
MA (1) MA41213A (cg-RX-API-DMAC7.html)
MX (1) MX2017008184A (cg-RX-API-DMAC7.html)
TW (1) TW201625658A (cg-RX-API-DMAC7.html)
WO (1) WO2016100569A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201704876B (cg-RX-API-DMAC7.html)

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Also Published As

Publication number Publication date
CN107250145A (zh) 2017-10-13
EP3233879A1 (en) 2017-10-25
HK1245800A1 (zh) 2018-08-31
US20160176910A1 (en) 2016-06-23
MA41213A (fr) 2017-10-24
MX2017008184A (es) 2018-03-06
WO2016100569A1 (en) 2016-06-23
ZA201704876B (en) 2020-01-29
US20180155384A1 (en) 2018-06-07
EP3233879A4 (en) 2018-09-19
AU2015364630A1 (en) 2017-07-06
US9890188B2 (en) 2018-02-13
CA2970936A1 (en) 2016-06-23
JP2017538722A (ja) 2017-12-28

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