TW201542567A - 用於增進先天性免疫反應之化合物及方法 - Google Patents

Info

Publication number

TW201542567A

TW201542567A TW104126180A TW104126180A TW201542567A TW 201542567 A TW201542567 A TW 201542567A TW 104126180 A TW104126180 A TW 104126180A TW 104126180 A TW104126180 A TW 104126180A TW 201542567 A TW201542567 A TW 201542567A

Authority

TW

Taiwan

Prior art keywords

group

hydrogen

trifluoromethyl

methyl

compound

Prior art date

2011-10-21

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• 150000001875 compounds Chemical class 0.000 title claims abstract description 201
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• 238000000034 method Methods 0.000 title abstract description 97
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• 150000003839 salts Chemical class 0.000 claims abstract description 64
• 239000008194 pharmaceutical composition Substances 0.000 claims abstract description 5
• 239000001257 hydrogen Substances 0.000 claims description 270
• 229910052739 hydrogen Inorganic materials 0.000 claims description 270
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 158
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 155
• 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims description 107
• 125000001072 heteroaryl group Chemical group 0.000 claims description 83
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• 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims description 65
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• 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims description 12
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