TW201107346A - Tumor therapy with an anti-VEGF antibody - Google Patents

Tumor therapy with an anti-VEGF antibody Download PDF

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Publication number
TW201107346A
TW201107346A TW099141756A TW99141756A TW201107346A TW 201107346 A TW201107346 A TW 201107346A TW 099141756 A TW099141756 A TW 099141756A TW 99141756 A TW99141756 A TW 99141756A TW 201107346 A TW201107346 A TW 201107346A
Authority
TW
Taiwan
Prior art keywords
cancer
antibody
her2
treatment
patient
Prior art date
Application number
TW099141756A
Other languages
English (en)
Chinese (zh)
Inventor
Thomas Friess
Max Hasmann
Werner Scheuer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37607207&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW201107346(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of TW201107346A publication Critical patent/TW201107346A/zh

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
TW099141756A 2006-08-21 2007-08-20 Tumor therapy with an anti-VEGF antibody TW201107346A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06017330 2006-08-21

Publications (1)

Publication Number Publication Date
TW201107346A true TW201107346A (en) 2011-03-01

Family

ID=37607207

Family Applications (2)

Application Number Title Priority Date Filing Date
TW099141756A TW201107346A (en) 2006-08-21 2007-08-20 Tumor therapy with an anti-VEGF antibody
TW096130765A TW200825106A (en) 2006-08-21 2007-08-20 Tumor therapy with an anti-VEGF antibody

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW096130765A TW200825106A (en) 2006-08-21 2007-08-20 Tumor therapy with an anti-VEGF antibody

Country Status (28)

Country Link
US (6) US20080050385A1 (https=)
EP (2) EP2056874B1 (https=)
JP (3) JP2010501498A (https=)
KR (1) KR101136763B1 (https=)
CN (1) CN101505792B (https=)
AR (1) AR062419A1 (https=)
AU (1) AU2007287794B2 (https=)
BR (1) BRPI0715829A2 (https=)
CA (1) CA2660681A1 (https=)
CL (1) CL2007002404A1 (https=)
CO (1) CO6150193A2 (https=)
CR (1) CR10590A (https=)
DK (1) DK2056874T3 (https=)
ES (2) ES2546066T3 (https=)
IL (2) IL196810A0 (https=)
MA (1) MA30654B1 (https=)
MX (1) MX2009001715A (https=)
MY (1) MY150756A (https=)
NO (1) NO20090450L (https=)
NZ (1) NZ574580A (https=)
PE (1) PE20080911A1 (https=)
PL (1) PL2056874T3 (https=)
RU (1) RU2528884C2 (https=)
SG (1) SG174090A1 (https=)
SI (1) SI2056874T1 (https=)
TW (2) TW201107346A (https=)
WO (1) WO2008022746A1 (https=)
ZA (1) ZA200901200B (https=)

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KR20160141857A (ko) 2014-04-25 2016-12-09 제넨테크, 인크. 트라스투주맙-mcc-dm1 및 퍼투주맙을 이용하는 초기 유방암의 치료방법
TW201619200A (zh) * 2014-10-10 2016-06-01 麥迪紐有限責任公司 人類化抗-ox40抗體及其用途
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CN106729743B (zh) 2015-11-23 2021-09-21 四川科伦博泰生物医药股份有限公司 抗ErbB2抗体-药物偶联物及其组合物、制备方法和应用
TWI734775B (zh) 2016-04-26 2021-08-01 美商美國泰福生技股份有限公司 細胞培養基
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TW202508629A (zh) 2017-01-17 2025-03-01 美商建南德克公司 皮下her2抗體調配物
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Also Published As

Publication number Publication date
KR101136763B1 (ko) 2012-04-24
CR10590A (es) 2009-03-20
BRPI0715829A2 (pt) 2013-07-23
RU2528884C2 (ru) 2014-09-20
EP2056874A1 (en) 2009-05-13
SG174090A1 (en) 2011-09-29
NO20090450L (no) 2009-02-27
IL238045A0 (en) 2015-05-31
MX2009001715A (es) 2009-02-25
AU2007287794A1 (en) 2008-02-28
ES2392630T3 (es) 2012-12-12
CL2007002404A1 (es) 2008-04-18
US20150239969A1 (en) 2015-08-27
AR062419A1 (es) 2008-11-05
TW200825106A (en) 2008-06-16
EP2441472A1 (en) 2012-04-18
US20080050385A1 (en) 2008-02-28
IL196810A0 (en) 2011-08-01
MA30654B1 (fr) 2009-08-03
US20110223159A1 (en) 2011-09-15
MY150756A (en) 2014-02-28
PE20080911A1 (es) 2008-08-15
CN101505792B (zh) 2012-10-03
RU2009110102A (ru) 2010-09-27
EP2441472B1 (en) 2015-06-10
CO6150193A2 (es) 2010-04-20
HK1134441A1 (en) 2010-04-30
JP2010501498A (ja) 2010-01-21
CN101505792A (zh) 2009-08-12
PL2056874T3 (pl) 2013-02-28
WO2008022746A1 (en) 2008-02-28
JP2013163687A (ja) 2013-08-22
EP2056874B1 (en) 2012-09-19
CA2660681A1 (en) 2008-02-28
DK2056874T3 (da) 2012-10-15
SI2056874T1 (sl) 2012-12-31
US20180251536A1 (en) 2018-09-06
ES2546066T3 (es) 2015-09-18
AU2007287794B2 (en) 2013-03-28
US20100285010A1 (en) 2010-11-11
US20130183292A1 (en) 2013-07-18
NZ574580A (en) 2011-12-22
ZA200901200B (en) 2013-08-28
JP2015214582A (ja) 2015-12-03
KR20090032136A (ko) 2009-03-31

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