TW200900083A - Polyglutamate conjugates and polyglutamate-amino acid conjugates having a plurality of drugs - Google Patents
Polyglutamate conjugates and polyglutamate-amino acid conjugates having a plurality of drugs Download PDFInfo
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- TW200900083A TW200900083A TW097117169A TW97117169A TW200900083A TW 200900083 A TW200900083 A TW 200900083A TW 097117169 A TW097117169 A TW 097117169A TW 97117169 A TW97117169 A TW 97117169A TW 200900083 A TW200900083 A TW 200900083A
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
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| WO (1) | WO2008141110A2 (enExample) |
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| US9393315B2 (en) | 2011-06-08 | 2016-07-19 | Nitto Denko Corporation | Compounds for targeting drug delivery and enhancing siRNA activity |
| AU2006322254B2 (en) | 2005-12-05 | 2012-08-02 | Nitto Denko Corporation | Polyglutamate-amino acid conjugates and methods |
| US20080181852A1 (en) * | 2007-01-29 | 2008-07-31 | Nitto Denko Corporation | Multi-functional Drug Carriers |
| CN101674852A (zh) * | 2007-04-10 | 2010-03-17 | 日东电工株式会社 | 多功能聚谷氨酸盐药物载体 |
| JP5341879B2 (ja) * | 2007-05-09 | 2013-11-13 | 日東電工株式会社 | 疎水性化合物及びポリアミノ酸複合体を含む組成物 |
| JP2011513412A (ja) * | 2008-03-06 | 2011-04-28 | 日東電工株式会社 | ポリマーパクリタキセル結合体を含む癌を治療するための薬学組成物 |
| WO2009141826A2 (en) * | 2008-05-22 | 2009-11-26 | Ramot At Tel Aviv University Ltd. | Novel conjugates of polymers having a therapeutically active agent and an angiogenesis targeting moiety attached thereto and uses thereof in the treatment of angiogenesis related diseases |
| EP2303288A4 (en) | 2008-05-22 | 2015-04-22 | Univ Ramot | CONJUGATES OF A POLYMER, BISPHOSPHONATE AND ANTI-ANGIOGENESIS AGENT AND USES THEREOF IN THE TREATMENT AND MONITORING OF DISEASES RELATING TO BONES |
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- 2008-05-08 CN CN200880019839A patent/CN101707869A/zh active Pending
- 2008-05-08 EP EP08769346A patent/EP2155253A2/en not_active Withdrawn
- 2008-05-09 TW TW097117169A patent/TW200900083A/zh unknown
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| CN101707869A (zh) | 2010-05-12 |
| WO2008141110A2 (en) | 2008-11-20 |
| WO2008141110A3 (en) | 2009-06-04 |
| US20080279778A1 (en) | 2008-11-13 |
| EP2155253A2 (en) | 2010-02-24 |
| JP2010526917A (ja) | 2010-08-05 |
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