TW200718692A - Dihydrobenzofuran derivatives and uses thereof - Google Patents
Dihydrobenzofuran derivatives and uses thereofInfo
- Publication number
- TW200718692A TW200718692A TW095114317A TW95114317A TW200718692A TW 200718692 A TW200718692 A TW 200718692A TW 095114317 A TW095114317 A TW 095114317A TW 95114317 A TW95114317 A TW 95114317A TW 200718692 A TW200718692 A TW 200718692A
- Authority
- TW
- Taiwan
- Prior art keywords
- compounds
- dihydrobenzofuran derivatives
- agonists
- dihydrobenzofuran
- derivatives
- Prior art date
Links
- HBEDSQVIWPRPAY-UHFFFAOYSA-N 2,3-dihydrobenzofuran Chemical class C1=CC=C2OCCC2=C1 HBEDSQVIWPRPAY-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000040125 5-hydroxytryptamine receptor family Human genes 0.000 abstract 1
- 108091032151 5-hydroxytryptamine receptor family Proteins 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000004031 partial agonist Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67415005P | 2005-04-22 | 2005-04-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200718692A true TW200718692A (en) | 2007-05-16 |
Family
ID=36968764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW095114317A TW200718692A (en) | 2005-04-22 | 2006-04-21 | Dihydrobenzofuran derivatives and uses thereof |
Country Status (13)
Country | Link |
---|---|
US (1) | US7402687B2 (zh) |
EP (1) | EP1871755A1 (zh) |
JP (1) | JP2008538572A (zh) |
CN (1) | CN101175740A (zh) |
AR (1) | AR056980A1 (zh) |
AU (1) | AU2006239920A1 (zh) |
BR (1) | BRPI0608475A2 (zh) |
CA (1) | CA2604916A1 (zh) |
GT (1) | GT200600164A (zh) |
MX (1) | MX2007012883A (zh) |
PE (1) | PE20061298A1 (zh) |
TW (1) | TW200718692A (zh) |
WO (1) | WO2006116150A1 (zh) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0210397D0 (en) | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
GT200500296A (es) * | 2004-10-21 | 2006-10-02 | Sintesis asimetrica de derivados del dehidrobenzofurano | |
GT200500297A (es) * | 2004-10-21 | 2006-10-27 | Sintesis asimetrica de dehidrobenzofuranos sustituidos | |
MX2007012883A (es) | 2005-04-22 | 2007-12-10 | Wyeth Corp | Derivados de dihidrobenzofurano y usos de los mismos. |
TW200722081A (en) * | 2005-04-22 | 2007-06-16 | Wyeth Corp | New therapeutic combinations for the treatment or prevention of depression |
EP1871358A1 (en) * | 2005-04-22 | 2008-01-02 | Wyeth | Benzofuranyl alkanamine derivatives and uses thereof as 5-ht2c agonists |
AR054035A1 (es) * | 2005-04-22 | 2007-05-30 | Wyeth Corp | Derivados benzodioxano y benzodioxolano y uso de los mismos |
CA2605447A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Therapeutic combinations for the treatment or prevention of psychotic disorders |
BRPI0609988A2 (pt) * | 2005-04-22 | 2010-05-18 | Wyeth Corp | derivados de diidrobenzofurano e usos dos mesmos |
JP2008538577A (ja) * | 2005-04-22 | 2008-10-30 | ワイス | ジヒドロベンゾフラン誘導体およびその使用 |
CA2605117A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Treatment of pain |
CN101203217A (zh) * | 2005-04-24 | 2008-06-18 | 惠氏公司 | 调节膀胱功能的方法 |
AU2007230977A1 (en) * | 2006-03-24 | 2007-10-04 | Wyeth | Methods for treating cognitive and other disorders |
JP5528699B2 (ja) | 2006-05-16 | 2014-06-25 | 武田薬品工業株式会社 | 縮合複素環化合物およびその用途 |
US8241357B2 (en) * | 2007-04-25 | 2012-08-14 | Jmea Corporation | Prosthesis with a selectively applied bone growth promoting agent |
CA2695634C (en) | 2007-08-06 | 2018-01-23 | Serenity Pharmaceuticals Corporation | Methods and devices for desmopressin drug delivery |
EP2789338A3 (en) | 2007-11-15 | 2015-01-14 | Takeda Pharmaceutical Company Limited | Condensed pyridine derivate and use thereof |
SG157299A1 (en) * | 2008-05-09 | 2009-12-29 | Agency Science Tech & Res | Diagnosis and treatment of kawasaki disease |
US20100286045A1 (en) | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
LT3225250T (lt) | 2008-05-21 | 2019-11-11 | Ferring Bv | Burnoje disperguojamas desmopresinas, skirtas nikturijos nepertraukiamo miego pirminio periodo pailginimui |
US11963995B2 (en) | 2008-05-21 | 2024-04-23 | Ferring B.V. | Methods comprising desmopressin |
CN101712879B (zh) * | 2009-09-23 | 2013-03-20 | 中国科学技术大学 | 制备2,3-二氢苯并呋喃和生物油的方法及其专用装置 |
EP2510949A4 (en) | 2009-12-11 | 2013-11-13 | Astellas Pharma Inc | THERAPEUTICS FOR FIBROMYALGIA |
CN102250048B (zh) * | 2011-06-03 | 2013-06-05 | 浙江工业大学 | 2-苯硒基甲基-2,3-二氢苯并呋喃及其制备与应用 |
WO2015066344A1 (en) | 2013-11-01 | 2015-05-07 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists and compositions and methods of use |
JPWO2019131902A1 (ja) | 2017-12-27 | 2020-12-10 | 武田薬品工業株式会社 | 腹圧性尿失禁および便失禁の治療薬 |
BR112020014428A2 (pt) | 2018-01-19 | 2020-12-01 | Cytokinetics, Inc. | composto, composição farmacêutica, e, métodos para o tratamento de uma doença cardíaca em um indivíduo, para o tratamento de uma doença ou condição que está associada com cavidade ventricular esquerda pequena e obliteração da cavidade, contração hiperdinâmica do ventrículo esquerdo, isquemia do miocárdio ou fibrose cardíaca, para o tratamento de uma doença ou condição selecionada dentre distrofias musculares e doenças de armazenamento do glicogênio e para inibição do sarcômero cardíaco |
EP3814342B1 (en) | 2018-06-26 | 2022-07-27 | Cytokinetics, Inc. | Cardiac sarcomere inhibitors |
EP4021433B1 (en) | 2019-08-26 | 2023-10-04 | Period Pill BV | Treatment of menstrual cycle-induced symptoms |
EP3878447A1 (en) | 2020-03-11 | 2021-09-15 | InterAx Biotech AG | Beta adrenergic receptor antagonists |
AU2022229390A1 (en) | 2021-03-04 | 2023-09-21 | Cytokinetics, Inc. | Cardiac sarcomere inhibitors |
Family Cites Families (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2554736A (en) * | 1951-05-29 | Tertiary aminoalkyl-iminodibenzyls | ||
GB1422263A (en) | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
US4314081A (en) | 1974-01-10 | 1982-02-02 | Eli Lilly And Company | Arloxyphenylpropylamines |
NL7503310A (nl) | 1975-03-20 | 1976-09-22 | Philips Nv | Verbindingen met antidepressieve werking. |
GB1526331A (en) | 1976-01-14 | 1978-09-27 | Kefalas As | Phthalanes |
US4210754A (en) | 1977-02-01 | 1980-07-01 | Hoffmann-La Roche Inc. | Morpholino containing benzamides |
IL56369A (en) | 1978-01-20 | 1984-05-31 | Erba Farmitalia | Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them |
US4536518A (en) | 1979-11-01 | 1985-08-20 | Pfizer Inc. | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
FR2508035A1 (fr) * | 1981-06-23 | 1982-12-24 | Fabre Sa Pierre | Derives d'aryl-1-aminomethyl-2 cyclopropanes carboxamides (z), leur preparation et leur application en tant que medicaments utiles dans le traitement des troubles du systeme nerveux central |
US4535186A (en) | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
GB8814057D0 (en) | 1988-06-14 | 1988-07-20 | Lundbeck & Co As H | New enantiomers & their isolation |
DE4200259A1 (de) * | 1992-01-08 | 1993-07-15 | Asta Medica Ag | Neue 1,2,4-triaminobenzol-derivate und verfahren zu deren herstellung |
US6765008B1 (en) * | 1992-12-17 | 2004-07-20 | Pfizer Inc | Pyrrolopyrimidines as CRF antagonists |
TW444018B (en) * | 1992-12-17 | 2001-07-01 | Pfizer | Pyrazolopyrimidines |
RU2142946C1 (ru) * | 1992-12-17 | 1999-12-20 | Пфайзер Инк. | Производные пиразола и фармацевтическая композиция, содержащая их |
ATE213407T1 (de) * | 1993-06-28 | 2002-03-15 | American Home Prod | Neue behandlungsmethoden durch verwendung von phenethylderivaten |
US5705646A (en) * | 1993-09-30 | 1998-01-06 | Pfizer Inc. | Substituted pyrazoles as CRF antagonists |
US5668145A (en) * | 1993-11-12 | 1997-09-16 | Pfizer Inc. | Amino-substituted pyrazoles having CRF antagonistic activity |
CN1104418C (zh) * | 1994-06-15 | 2003-04-02 | 大塚制药株式会社 | 苯并杂环衍生物 |
US5565483A (en) * | 1995-06-07 | 1996-10-15 | Bristol-Myers Squibb Company | 3-substituted oxindole derivatives as potassium channel modulators |
TW359669B (en) * | 1995-12-15 | 1999-06-01 | Otsuka Pharma Co Ltd | Benzazepine derivatives |
US6274171B1 (en) * | 1996-03-25 | 2001-08-14 | American Home Products Corporation | Extended release formulation of venlafaxine hydrochloride |
US6194407B1 (en) * | 1997-07-30 | 2001-02-27 | American Home Products Corporation | Tricyclic pyrido vasopressin agonists |
US6090803A (en) * | 1998-07-24 | 2000-07-18 | American Home Products Corporation | Tricyclic vasopressin agonists |
JP2002535396A (ja) * | 1999-01-27 | 2002-10-22 | イーライ・リリー・アンド・カンパニー | セロトニン(5−ht(2c))アゴニストとしてのアミノアルキルベンゾフラン類 |
US7045545B1 (en) * | 1999-01-27 | 2006-05-16 | Eli Lilly And Company | Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists |
WO2002080898A2 (en) * | 2001-04-04 | 2002-10-17 | Wyeth | Methods for treating hyperactive gastric motility |
US20040235856A1 (en) * | 2003-04-25 | 2004-11-25 | Pfizer Inc | Treatment of incontinence |
US7728155B2 (en) | 2003-10-24 | 2010-06-01 | Wyeth Llc | Dihydrobenzofuranyl alkanamines and methods for using same as cns agents |
US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
WO2006000902A1 (en) * | 2004-06-25 | 2006-01-05 | Pfizer Products Inc. | Dihydrobenzofuran compounds and uses thereof |
GT200500296A (es) * | 2004-10-21 | 2006-10-02 | Sintesis asimetrica de derivados del dehidrobenzofurano | |
GT200500297A (es) * | 2004-10-21 | 2006-10-27 | Sintesis asimetrica de dehidrobenzofuranos sustituidos | |
BRPI0609988A2 (pt) * | 2005-04-22 | 2010-05-18 | Wyeth Corp | derivados de diidrobenzofurano e usos dos mesmos |
EP1879875A1 (en) * | 2005-04-22 | 2008-01-23 | Wyeth | Crystal forms opf {[(2r)-7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-benzofuran-2-yl]methyl}amine hydrochloride |
JP2008538577A (ja) * | 2005-04-22 | 2008-10-30 | ワイス | ジヒドロベンゾフラン誘導体およびその使用 |
RU2007139541A (ru) * | 2005-04-22 | 2009-05-27 | Вайет (Us) | Производные хромана и хромена и их применение |
CA2605447A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Therapeutic combinations for the treatment or prevention of psychotic disorders |
EP1871358A1 (en) * | 2005-04-22 | 2008-01-02 | Wyeth | Benzofuranyl alkanamine derivatives and uses thereof as 5-ht2c agonists |
AR054035A1 (es) * | 2005-04-22 | 2007-05-30 | Wyeth Corp | Derivados benzodioxano y benzodioxolano y uso de los mismos |
TW200722081A (en) * | 2005-04-22 | 2007-06-16 | Wyeth Corp | New therapeutic combinations for the treatment or prevention of depression |
WO2006116148A2 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | (7-arlysubstituted 2, 3-dihydr0-1-benz0furan-2-yl) alkylamines in the treatment' of substance abuse |
CA2605117A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Treatment of pain |
MX2007012883A (es) | 2005-04-22 | 2007-12-10 | Wyeth Corp | Derivados de dihidrobenzofurano y usos de los mismos. |
CN101203217A (zh) * | 2005-04-24 | 2008-06-18 | 惠氏公司 | 调节膀胱功能的方法 |
-
2006
- 2006-04-21 MX MX2007012883A patent/MX2007012883A/es not_active Application Discontinuation
- 2006-04-21 EP EP06758483A patent/EP1871755A1/en not_active Withdrawn
- 2006-04-21 JP JP2008507944A patent/JP2008538572A/ja active Pending
- 2006-04-21 US US11/409,479 patent/US7402687B2/en not_active Expired - Fee Related
- 2006-04-21 BR BRPI0608475-3A patent/BRPI0608475A2/pt not_active Application Discontinuation
- 2006-04-21 PE PE2006000419A patent/PE20061298A1/es not_active Application Discontinuation
- 2006-04-21 GT GT200600164A patent/GT200600164A/es unknown
- 2006-04-21 AR ARP060101593A patent/AR056980A1/es not_active Application Discontinuation
- 2006-04-21 CN CNA2006800167696A patent/CN101175740A/zh active Pending
- 2006-04-21 TW TW095114317A patent/TW200718692A/zh unknown
- 2006-04-21 WO PCT/US2006/015192 patent/WO2006116150A1/en active Application Filing
- 2006-04-21 AU AU2006239920A patent/AU2006239920A1/en not_active Abandoned
- 2006-04-21 CA CA002604916A patent/CA2604916A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1871755A1 (en) | 2008-01-02 |
PE20061298A1 (es) | 2006-12-24 |
US7402687B2 (en) | 2008-07-22 |
CA2604916A1 (en) | 2006-11-02 |
JP2008538572A (ja) | 2008-10-30 |
WO2006116150A1 (en) | 2006-11-02 |
BRPI0608475A2 (pt) | 2010-01-05 |
GT200600164A (es) | 2007-03-14 |
AR056980A1 (es) | 2007-11-07 |
AU2006239920A1 (en) | 2006-11-02 |
MX2007012883A (es) | 2007-12-10 |
CN101175740A (zh) | 2008-05-07 |
US20060241176A1 (en) | 2006-10-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TW200718692A (en) | Dihydrobenzofuran derivatives and uses thereof | |
TW200719886A (en) | Dihydrobenzofuran derivatives and uses thereof | |
TW200720266A (en) | Benzodioxane and benzodioxolan derivatives and uses thereof | |
TW200716595A (en) | Chromane and chromene derivatives and uses thereof | |
MX2007013021A (es) | Derivados de benzofuranil-alcanamina y usos de los mismos como agonistas de 5-ht2c. | |
WO2006050007A3 (en) | Substituted indolizines and derivatives as cns agents | |
TW200833686A (en) | Fused bicyclic derivatives of 2,4-diaminopyrimidine as ALK and c-Met inhibitors | |
MY147390A (en) | Substituted isoindoles as bace inhibitors and their use | |
TNSN08089A1 (en) | Substituted benzimidazoles and methods of preparation | |
WO2007140439A3 (en) | Compounds as cannabinoid receptor ligands and uses thereof | |
GEP20115174B (en) | Triazolopyrazine derivatives useful as anti-cancer agents | |
NO20062139L (no) | Dihydrobenzofuranyl-alkanaminderivater som 5HT2C-agonister | |
MY145609A (en) | Piperidin-4-yl-pyridazin-3-ylamine derivatives as fast dissociating dopamine 2 receptor antagonists | |
MX2010005649A (es) | Compuestos novedosos como ligandos del receptor canabinoide y sus usos. | |
IL186777A0 (en) | (3,4-dihydro-quinazolin-2-yl) - (2-aryloxy-ethyl) - amines having an activity on the 5 - ht receptor | |
PL1831152T3 (pl) | Pochodne tetraliny i indanu oraz ich zastosowanie jako antagonistów 5-HT | |
EA200601194A1 (ru) | Новые производные бензофурана, используемые для профилактики или лечения нарушений, связанных с 5-ht-рецептором | |
UA98772C2 (ru) | Производные циклопропиламина как модуляторы н3-гистаминового рецептора | |
PL1831191T3 (pl) | Pochodne chromanu i ich zastosowanie jako ligandów receptorów 5-HT | |
MX2009011415A (es) | Derivados de 4-alcoxipiridazina como antagonistas del receptor de dopamina 2 de rapida disociacion. | |
WO2008052075A3 (en) | Benzoxazine derivatives and uses thereof | |
WO2008052088A8 (en) | Chromane derivatives, synthesis thereof, and intermediates thereto | |
ATE443707T1 (de) | Isoxazolin-indol-derivate mit verbesserter antipsychotischer und anxiolytischer aktivität | |
WO2008052078A3 (en) | Benzoxathiine and benzoxathiole derivatives and uses thereof | |
MX2009005242A (es) | Derivados de 3-(hetero)arilisoquinolinamida sustituida en posición 5, 6 o 7 y uso terapeutico del mismo. |