TW200716638A - Preparation of famciclovir and other purine derivatives - Google Patents

Preparation of famciclovir and other purine derivatives

Info

Publication number
TW200716638A
TW200716638A TW095117840A TW95117840A TW200716638A TW 200716638 A TW200716638 A TW 200716638A TW 095117840 A TW095117840 A TW 095117840A TW 95117840 A TW95117840 A TW 95117840A TW 200716638 A TW200716638 A TW 200716638A
Authority
TW
Taiwan
Prior art keywords
purine derivatives
famciclovir
preparation
purine
substituted
Prior art date
Application number
TW095117840A
Other languages
English (en)
Chinese (zh)
Inventor
Liang He
wei-ping Jiang
Original Assignee
Arrow Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arrow Int Ltd filed Critical Arrow Int Ltd
Publication of TW200716638A publication Critical patent/TW200716638A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TW095117840A 2005-05-20 2006-05-19 Preparation of famciclovir and other purine derivatives TW200716638A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0510345A GB2426247A (en) 2005-05-20 2005-05-20 Methods of preparing purine derivatives such as famciclovir

Publications (1)

Publication Number Publication Date
TW200716638A true TW200716638A (en) 2007-05-01

Family

ID=34834391

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095117840A TW200716638A (en) 2005-05-20 2006-05-19 Preparation of famciclovir and other purine derivatives

Country Status (17)

Country Link
US (1) US7601835B2 (OSRAM)
EP (1) EP1883639B1 (OSRAM)
JP (1) JP5227166B2 (OSRAM)
CN (1) CN101233134B (OSRAM)
AT (1) ATE479688T1 (OSRAM)
AU (1) AU2006248745B2 (OSRAM)
BR (1) BRPI0609632A2 (OSRAM)
CA (1) CA2608490C (OSRAM)
DE (1) DE602006016593D1 (OSRAM)
DK (1) DK1883639T3 (OSRAM)
ES (1) ES2351925T3 (OSRAM)
GB (1) GB2426247A (OSRAM)
NZ (1) NZ563636A (OSRAM)
PL (1) PL1883639T3 (OSRAM)
PT (1) PT1883639E (OSRAM)
TW (1) TW200716638A (OSRAM)
WO (1) WO2006123175A1 (OSRAM)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2496684A1 (en) * 2002-08-26 2004-03-04 Teva Pharmaceutical Industries Ltd Crystalline solid famciclovir forms i, ii, iii and preparation thereof
WO2004099208A1 (en) * 2003-04-30 2004-11-18 Teva Pharmaceutical Industries Ltd. Process for the preparation of famciclovir
TW200613304A (en) * 2004-05-18 2006-05-01 Teva Pharma Drying process for preparing crystalline solid famciclovir
WO2008072074A1 (en) * 2006-12-11 2008-06-19 Aurobindo Pharma Limited An improved process for the preparation of purine derivative
CN101555249B (zh) * 2008-04-08 2011-05-11 浙江海正药业股份有限公司 泛昔洛韦的合成方法
CN102924455A (zh) * 2011-08-11 2013-02-13 重庆圣华曦药业股份有限公司 一种泛昔洛韦中间体的合成方法
CN104496991A (zh) * 2014-11-04 2015-04-08 常州康丽制药有限公司 高品质2-氨基-6-氯-9-(4-羟基-3–羟甲基丁基)嘌呤的制备方法
CN104744472A (zh) * 2015-03-12 2015-07-01 常州康丽制药有限公司 高品质2-氨基-6-氯-9-(4-羟基-3-羟甲基丁基)嘌呤的制备方法
CN109456329B (zh) * 2018-11-19 2021-03-09 迪嘉药业集团有限公司 一种泛昔洛韦的制备方法
ES3037292T3 (en) 2019-12-11 2025-09-30 Taro Pharma Ind Preparation of trifarotene and intermediates and polymorphs thereof
CN112979653A (zh) * 2019-12-12 2021-06-18 上药康丽（常州）药业有限公司 一种利用微通道反应器合成泛昔洛韦的方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0141927B1 (en) * 1983-08-18 1991-10-30 Beecham Group Plc Antiviral guanine derivatives
US5684153A (en) 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
EP0182024B1 (en) * 1984-09-20 1991-04-03 Beecham Group Plc Purine derivatives and their pharmaceutical use
SE8406538D0 (sv) 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
GB8817607D0 (en) * 1988-07-23 1988-09-01 Beecham Group Plc Novel process
GB8822236D0 (en) 1988-09-21 1988-10-26 Beecham Group Plc Chemical process
GB9402161D0 (en) 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
GB9407698D0 (en) 1994-04-19 1994-06-15 Smithkline Beecham Plc Pharmaceuticals
JPH11180983A (ja) 1997-12-24 1999-07-06 Sumika Fine Chemicals Co Ltd ９置換２−アミノ−６−ハロゲノプリンおよびその製法
GB9807116D0 (en) * 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
GB9807114D0 (en) * 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
SI20022A (sl) * 1998-07-29 2000-02-29 Kemijski inštitut Alkilno substituirani purinovi derivati in njihova priprava
DE60202245T2 (de) 2001-08-30 2005-09-01 Ajinomoto Co., Inc. Herstellungsmethode von Famciclovir und Herstellungs- bzw. Kristallisationsmethode eines entsprechenden Intermediates
JP2003146988A (ja) * 2001-08-30 2003-05-21 Ajinomoto Co Inc ファムシクロビルの製造方法、並びにその中間体の製造および晶析方法
KR100573860B1 (ko) 2003-06-13 2006-04-25 경동제약 주식회사 2-아미노-9-(2-치환에틸)푸린을 이용한 9-[4-아세톡시-3-(아세톡시메틸)부트-1-일]-2-아미노푸린의 제조방법
US20050215787A1 (en) * 2004-03-26 2005-09-29 Joshi Ramesh A An improved process for the preparation of purines

Also Published As

Publication number Publication date
JP2008540628A (ja) 2008-11-20
CA2608490C (en) 2013-09-10
DE602006016593D1 (de) 2010-10-14
US20060264629A1 (en) 2006-11-23
GB0510345D0 (en) 2005-06-29
US7601835B2 (en) 2009-10-13
CN101233134B (zh) 2013-01-23
GB2426247A (en) 2006-11-22
AU2006248745A1 (en) 2006-11-23
PT1883639E (pt) 2010-12-07
ES2351925T3 (es) 2011-02-14
CN101233134A (zh) 2008-07-30
AU2006248745B2 (en) 2011-06-23
BRPI0609632A2 (pt) 2011-10-18
JP5227166B2 (ja) 2013-07-03
EP1883639A1 (en) 2008-02-06
DK1883639T3 (da) 2010-11-15
ATE479688T1 (de) 2010-09-15
PL1883639T3 (pl) 2011-04-29
EP1883639B1 (en) 2010-09-01
CA2608490A1 (en) 2006-11-23
NZ563636A (en) 2010-10-29
WO2006123175A1 (en) 2006-11-23

Similar Documents

Publication Publication Date Title
MY145652A (en) Process for the manufacture of dihydropteridinones
MY145604A (en) Process for the preparation of chiral 8-(3-aminopiperidine-1-yl)-xanthines
WO2006021379A8 (de) Dihydropteridinonderivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
ZA200703115B (en) Dimensionally stable low carbohydrate pet food
WO2007021937A3 (en) Unsaturated heterocyclic derivatives
WO2008017079A3 (en) Dyes and precursors and conjugates thereof
WO2007144779A3 (en) Compositions comprising porphyra and methods of making and using thereof
TW200716638A (en) Preparation of famciclovir and other purine derivatives
WO2006066950A3 (de) Tricyclische aminoalkohole, verfahren zu ihrer herstellung und ihre verwendung als entzündungshemmer
WO2007115929A8 (de) Thiazolyl-dihydro-quinazoline
TW200732410A (en) Sprayable acoustic compositions
UA91733C2 (ru) Способ получения кристаллической формы орлистата
ZA200903193B (en) Novel Morphine derivatives
WO2007070494A3 (en) Heterocycles and derivatives thereof and methods of manufacture and therapeutic use
WO2007110068A3 (de) Neue isooxazol-derivate und deren verwendungen
TW200635500A (en) Novel medaka and preparation thereof
TH92432S (th) ที่นั่ง
TH95318S (th) ที่นั่ง
TH30445S1 (th) ที่นั่ง
TH92430S (th) ที่นั่ง
TH32858S1 (th) ที่นั่ง
WO2007049296A3 (en) Amorphous form of telithromycin
TH92432B (th) ที่นั่ง
TH95318B (th) ที่นั่ง
TH92201S (th) กระจก