ATE479688T1 - Herstellung von famciclovir und anderen purinderivaten - Google Patents

Herstellung von famciclovir und anderen purinderivaten

Info

Publication number
ATE479688T1
ATE479688T1 AT06743955T AT06743955T ATE479688T1 AT E479688 T1 ATE479688 T1 AT E479688T1 AT 06743955 T AT06743955 T AT 06743955T AT 06743955 T AT06743955 T AT 06743955T AT E479688 T1 ATE479688 T1 AT E479688T1
Authority
AT
Austria
Prior art keywords
purine derivatives
famciclovir
preparation
purine
substituted
Prior art date
Application number
AT06743955T
Other languages
English (en)
Inventor
Liang He
Weiping Jiang
Original Assignee
Arrow Int Ltd
Chongqing Shenghuaxi Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arrow Int Ltd, Chongqing Shenghuaxi Pharma Co filed Critical Arrow Int Ltd
Application granted granted Critical
Publication of ATE479688T1 publication Critical patent/ATE479688T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT06743955T 2005-05-20 2006-05-19 Herstellung von famciclovir und anderen purinderivaten ATE479688T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0510345A GB2426247A (en) 2005-05-20 2005-05-20 Methods of preparing purine derivatives such as famciclovir
PCT/GB2006/001877 WO2006123175A1 (en) 2005-05-20 2006-05-19 Preparation of famciclovir and other purine derivatives

Publications (1)

Publication Number Publication Date
ATE479688T1 true ATE479688T1 (de) 2010-09-15

Family

ID=34834391

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06743955T ATE479688T1 (de) 2005-05-20 2006-05-19 Herstellung von famciclovir und anderen purinderivaten

Country Status (17)

Country Link
US (1) US7601835B2 (de)
EP (1) EP1883639B1 (de)
JP (1) JP5227166B2 (de)
CN (1) CN101233134B (de)
AT (1) ATE479688T1 (de)
AU (1) AU2006248745B2 (de)
BR (1) BRPI0609632A2 (de)
CA (1) CA2608490C (de)
DE (1) DE602006016593D1 (de)
DK (1) DK1883639T3 (de)
ES (1) ES2351925T3 (de)
GB (1) GB2426247A (de)
NZ (1) NZ563636A (de)
PL (1) PL1883639T3 (de)
PT (1) PT1883639E (de)
TW (1) TW200716638A (de)
WO (1) WO2006123175A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004018470A2 (en) * 2002-08-26 2004-03-04 Teva Pharmaceutical Industries Ltd. Crystalline solid famciclovir forms i, ii, iii and preparation thereof
US20040266795A1 (en) * 2003-04-30 2004-12-30 Genny Shamai Process for the preparation of famciclovir
TW200613304A (en) * 2004-05-18 2006-05-01 Teva Pharma Drying process for preparing crystalline solid famciclovir
WO2008072074A1 (en) * 2006-12-11 2008-06-19 Aurobindo Pharma Limited An improved process for the preparation of purine derivative
CN101555249B (zh) * 2008-04-08 2011-05-11 浙江海正药业股份有限公司 泛昔洛韦的合成方法
CN102924455A (zh) * 2011-08-11 2013-02-13 重庆圣华曦药业股份有限公司 一种泛昔洛韦中间体的合成方法
CN104496991A (zh) * 2014-11-04 2015-04-08 常州康丽制药有限公司 高品质2-氨基-6-氯-9-(4-羟基-3–羟甲基丁基)嘌呤的制备方法
CN104744472A (zh) * 2015-03-12 2015-07-01 常州康丽制药有限公司 高品质2-氨基-6-氯-9-(4-羟基-3-羟甲基丁基)嘌呤的制备方法
CN109456329B (zh) * 2018-11-19 2021-03-09 迪嘉药业集团有限公司 一种泛昔洛韦的制备方法
IL293800A (en) 2019-12-11 2022-08-01 Taro Pharma Ind Preparation of triprotein and intermediate products and polymorphs thereof
CN112979653A (zh) * 2019-12-12 2021-06-18 上药康丽（常州）药业有限公司 一种利用微通道反应器合成泛昔洛韦的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5684153A (en) 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
EP0141927B1 (de) * 1983-08-18 1991-10-30 Beecham Group Plc Antivirale Guanin-Derivate
EP0182024B1 (de) * 1984-09-20 1991-04-03 Beecham Group Plc Purin-Derivate und ihre pharmazeutische Verwendung
SE8406538D0 (sv) 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
GB8817607D0 (en) * 1988-07-23 1988-09-01 Beecham Group Plc Novel process
GB8822236D0 (en) 1988-09-21 1988-10-26 Beecham Group Plc Chemical process
GB9402161D0 (en) 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
GB9407698D0 (en) 1994-04-19 1994-06-15 Smithkline Beecham Plc Pharmaceuticals
GB9807114D0 (en) * 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
GB9807116D0 (en) * 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
SI20022A (sl) * 1998-07-29 2000-02-29 Kemijski inštitut Alkilno substituirani purinovi derivati in njihova priprava
EP1288215B8 (de) 2001-08-30 2005-04-06 Ajinomoto Co., Inc. Herstellungsmethode von Famciclovir und Herstellungs- bzw. Kristallisationsmethode eines entsprechenden Intermediates
JP2003146988A (ja) * 2001-08-30 2003-05-21 Ajinomoto Co Inc ファムシクロビルの製造方法、並びにその中間体の製造および晶析方法
KR100573860B1 (ko) 2003-06-13 2006-04-25 경동제약 주식회사 2-아미노-9-(2-치환에틸)푸린을 이용한 9-[4-아세톡시-3-(아세톡시메틸)부트-1-일]-2-아미노푸린의 제조방법
US20050215787A1 (en) * 2004-03-26 2005-09-29 Joshi Ramesh A An improved process for the preparation of purines

Also Published As

Publication number Publication date
GB2426247A (en) 2006-11-22
PT1883639E (pt) 2010-12-07
AU2006248745A1 (en) 2006-11-23
EP1883639A1 (de) 2008-02-06
CN101233134A (zh) 2008-07-30
CN101233134B (zh) 2013-01-23
WO2006123175A1 (en) 2006-11-23
CA2608490C (en) 2013-09-10
US20060264629A1 (en) 2006-11-23
PL1883639T3 (pl) 2011-04-29
AU2006248745B2 (en) 2011-06-23
DE602006016593D1 (de) 2010-10-14
TW200716638A (en) 2007-05-01
GB0510345D0 (en) 2005-06-29
BRPI0609632A2 (pt) 2011-10-18
EP1883639B1 (de) 2010-09-01
DK1883639T3 (da) 2010-11-15
ES2351925T3 (es) 2011-02-14
US7601835B2 (en) 2009-10-13
JP2008540628A (ja) 2008-11-20
CA2608490A1 (en) 2006-11-23
NZ563636A (en) 2010-10-29
JP5227166B2 (ja) 2013-07-03

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