TW200600132A - Frequency assisted transdermal agent delivery method and system - Google Patents

Frequency assisted transdermal agent delivery method and system

Info

Publication number
TW200600132A
TW200600132A TW093132875A TW93132875A TW200600132A TW 200600132 A TW200600132 A TW 200600132A TW 093132875 A TW093132875 A TW 093132875A TW 93132875 A TW93132875 A TW 93132875A TW 200600132 A TW200600132 A TW 200600132A
Authority
TW
Taiwan
Prior art keywords
biologically active
active agent
delivery method
agent delivery
microprojection member
Prior art date
Application number
TW093132875A
Other languages
English (en)
Inventor
Keith T Chan
Weiqi Lin
Michel J N Cormier
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of TW200600132A publication Critical patent/TW200600132A/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Medical Informatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Radiology & Medical Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW093132875A 2004-01-09 2004-10-29 Frequency assisted transdermal agent delivery method and system TW200600132A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53527504P 2004-01-09 2004-01-09
US10/971,441 US20050153873A1 (en) 2004-01-09 2004-10-21 Frequency assisted transdermal agent delivery method and system

Publications (1)

Publication Number Publication Date
TW200600132A true TW200600132A (en) 2006-01-01

Family

ID=34806918

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093132875A TW200600132A (en) 2004-01-09 2004-10-29 Frequency assisted transdermal agent delivery method and system

Country Status (12)

Country Link
US (1) US20050153873A1 (zh)
EP (1) EP1706176A4 (zh)
JP (1) JP2007519446A (zh)
KR (1) KR20060134050A (zh)
CN (1) CN1946452A (zh)
AR (1) AR046697A1 (zh)
AU (1) AU2004314416A1 (zh)
BR (1) BRPI0417757A (zh)
CA (1) CA2552754A1 (zh)
MX (1) MXPA06007832A (zh)
TW (1) TW200600132A (zh)
WO (1) WO2005069758A2 (zh)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
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US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
GB0210397D0 (en) * 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
MX2007001667A (es) * 2004-08-11 2007-10-02 Johnson & Johnson Aparato y metodo para el suministro transdermico de peptidos natriureticos.
US8048017B2 (en) 2005-05-18 2011-11-01 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
WO2007059289A1 (en) * 2005-11-18 2007-05-24 3M Innovative Properties Company Microneedle arrays and methods of preparing same
WO2007061964A1 (en) * 2005-11-18 2007-05-31 3M Innovative Properties Company Methods for coating microneedles
WO2007064486A1 (en) * 2005-11-30 2007-06-07 3M Innovative Properties Company Microneedle arrays and methods of use thereof
US20090209899A1 (en) 2006-06-15 2009-08-20 Harry Unger Delivery system and process
DE102006028987A1 (de) * 2006-06-24 2007-12-27 Lts Lohmann Therapie-Systeme Ag Ultraschallverstärktes transdermales therapeutisches System
CA2667228C (en) 2006-10-23 2015-07-14 Micell Technologies, Inc. Holder for electrically charging a substrate during coating
US20080214987A1 (en) * 2006-12-22 2008-09-04 Nanomed Devices, Inc. Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances
US10525246B2 (en) 2006-12-22 2020-01-07 Nanomed Skincare, Inc. Microdevice and method for transdermal delivery and sampling of active substances
WO2008145323A1 (en) * 2007-05-31 2008-12-04 F. Hoffmann-La Roche Ag Pharmaceutical formulation for interferons
JP5451613B2 (ja) 2007-08-06 2014-03-26 アラーガン、インコーポレイテッド デスモプレシン薬物送達のための方法及びデバイス
WO2009051147A1 (ja) * 2007-10-18 2009-04-23 Hisamitsu Pharmaceutical Co., Inc. マイクロニードルデバイス
US20100293807A1 (en) * 2007-10-29 2010-11-25 Transpharma Medical, Ltd. Vertical patch drying
US20090157003A1 (en) * 2007-12-14 2009-06-18 Jones Daniel W Method And Apparatus For Occlusion Prevention And Remediation
CN103961792B (zh) * 2007-12-17 2016-09-21 新世界药品有限公司 整合的真皮内递送、诊断和通讯系统
ES2710454T3 (es) * 2008-05-21 2019-04-25 Ferring Bv Desmopresina bucodispersable para aumentar el periodo inicial de sueño ininterrumpido por nocturia
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
JP2011528275A (ja) * 2008-07-17 2011-11-17 ミセル テクノロジーズ，インク． 薬物送達医療デバイス
EP2323605A4 (en) * 2008-09-10 2014-02-05 Syneron Medical Ltd TRANSDERMAL RELEASE OF OLIGOSACCHARIDES
IT1394690B1 (it) * 2008-10-23 2012-07-13 Carli De Metodo di trattamento dermocosmetico della cute mediante applicazione di composizioni contenenti ngf.
SG173160A1 (en) * 2009-01-30 2011-08-29 Hisamitsu Pharmaceutical Co Microneedle device
EP2441437B1 (en) 2009-06-10 2018-08-08 Hisamitsu Pharmaceutical Co., Inc. Microneedle device
WO2011010605A1 (ja) 2009-07-23 2011-01-27 久光製薬株式会社 マイクロニードルアレイ
US7803762B1 (en) 2009-08-20 2010-09-28 The Medicines Company Ready-to-use bivalirudin compositions
WO2011097384A2 (en) * 2010-02-04 2011-08-11 Board Of Regents, The University Of Texas System Tumor targeted delivery of immunomodulators by nanoplymers
EP2636424A1 (de) * 2012-03-09 2013-09-11 LTS LOHMANN Therapie-Systeme AG Therapeutisches System mit hohlen Mikronadeln
JP6689187B2 (ja) * 2013-03-15 2020-04-28 コリウム， インコーポレイテッド 複数の衝突微小突起アプリケータおよび使用方法
DE102013005197A1 (de) * 2013-03-25 2014-09-25 Michael Horstmann Schwingendes Mikronadelpflaster
EP3139990A4 (en) 2014-05-06 2018-01-17 Mupharma Pty Ltd Non-invasive agent applicator
CN104056346B (zh) * 2014-06-16 2017-04-26 游学秋 异平面微针阵列及其制作方法
WO2016074040A2 (en) 2014-11-12 2016-05-19 Mupharma Pty Ltd Non-invasive agent applicator
JP6449057B2 (ja) * 2015-03-10 2019-01-09 国立研究開発法人産業技術総合研究所 ナノニードルアレイを用いた細胞への物質導入法
MX2019002835A (es) 2016-09-13 2019-09-04 Allergan Inc Composiciones no proteínicas de toxina clostridial.
EP3697382A1 (en) * 2017-10-16 2020-08-26 Massachusetts Institute Of Technology Compositions and methods to enhance ultrasound-mediated delivery of pharmaceutical agents
CN108969879B (zh) * 2018-06-05 2021-06-22 南京工业大学 一种复合微针及微针贴片
DE102019105694A1 (de) * 2019-03-06 2020-09-10 Lts Lohmann Therapie-Systeme Ag Mikronadelarray aufweisend ein wärmeerzeugendes Element
US20230039698A1 (en) * 2019-12-19 2023-02-09 Trimph Ip Pty Ltd Biocompatible Material

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ZA918528B (en) * 1990-10-29 1992-08-26 Alza Corp Iontophoretic delivery device and method of hydrating same
US6041253A (en) * 1995-12-18 2000-03-21 Massachusetts Institute Of Technology Effect of electric field and ultrasound for transdermal drug delivery
EP0925088A2 (en) * 1996-06-28 1999-06-30 Sontra Medical, L.P. Ultrasound enhancement of transdermal transport
DE69722414T2 (de) * 1996-07-03 2004-05-19 Altea Therapeutics Corp. Mehrfache mechanische mikroperforierung von haut oder schleimhäuten
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
CA2317777C (en) * 1998-01-08 2005-05-03 Sontra Medical, Inc. Sonophoretic enhanced transdermal transport
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US6620123B1 (en) * 1999-12-17 2003-09-16 Sontra Medical, Inc. Method and apparatus for producing homogenous cavitation to enhance transdermal transport

Also Published As

Publication number Publication date
AU2004314416A1 (en) 2005-08-04
KR20060134050A (ko) 2006-12-27
WO2005069758A3 (en) 2006-05-18
JP2007519446A (ja) 2007-07-19
EP1706176A4 (en) 2008-06-25
MXPA06007832A (es) 2007-01-26
CN1946452A (zh) 2007-04-11
US20050153873A1 (en) 2005-07-14
BRPI0417757A (pt) 2007-04-10
AR046697A1 (es) 2005-12-21
CA2552754A1 (en) 2005-08-04
EP1706176A2 (en) 2006-10-04
WO2005069758A2 (en) 2005-08-04

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