TW200503695A - Imidazole derivatives for treatment of allergic and hyperproliferative disorders - Google Patents
Imidazole derivatives for treatment of allergic and hyperproliferative disordersInfo
- Publication number
- TW200503695A TW200503695A TW093110069A TW93110069A TW200503695A TW 200503695 A TW200503695 A TW 200503695A TW 093110069 A TW093110069 A TW 093110069A TW 93110069 A TW93110069 A TW 93110069A TW 200503695 A TW200503695 A TW 200503695A
- Authority
- TW
- Taiwan
- Prior art keywords
- treatment
- allergic
- preferred embodiments
- imidazole derivatives
- hyperproliferative disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46209003P | 2003-04-10 | 2003-04-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200503695A true TW200503695A (en) | 2005-02-01 |
Family
ID=33299906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW093110069A TW200503695A (en) | 2003-04-10 | 2004-04-12 | Imidazole derivatives for treatment of allergic and hyperproliferative disorders |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20040229927A1 (zh) |
| EP (1) | EP1613310A1 (zh) |
| JP (1) | JP2006522820A (zh) |
| KR (1) | KR20050120711A (zh) |
| CN (1) | CN1826111A (zh) |
| AR (1) | AR045886A1 (zh) |
| AU (1) | AU2004229466A1 (zh) |
| BR (1) | BRPI0409097A (zh) |
| CA (1) | CA2521841A1 (zh) |
| MX (1) | MXJL05000041A (zh) |
| PL (1) | PL378919A1 (zh) |
| RU (1) | RU2005134670A (zh) |
| TW (1) | TW200503695A (zh) |
| WO (1) | WO2004091610A1 (zh) |
| ZA (1) | ZA200508108B (zh) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6911462B2 (en) * | 1998-05-22 | 2005-06-28 | Avanir Pharmaceuticals | Benzimidazole compounds for regulating IgE |
| US6919366B2 (en) * | 1998-05-22 | 2005-07-19 | Avanir Pharmaceuticals | Benzimidazole derivatives as modulators of IgE |
| WO2002072090A1 (en) * | 2001-03-12 | 2002-09-19 | Avanir Pharmaceuticals | Benzimidazole compounds for modulating ige and inhibiting cellular proliferation |
| TW200304820A (en) * | 2002-03-25 | 2003-10-16 | Avanir Pharmaceuticals | Use of benzimidazole analogs in the treatment of cell proliferation |
| WO2004024655A2 (en) | 2002-09-12 | 2004-03-25 | Avanir Pharmaceuticals | Phenyl-indole compounds for modulating ige and inhibiting cellular proliferation |
| TWI276631B (en) * | 2002-09-12 | 2007-03-21 | Avanir Pharmaceuticals | Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation |
| JP2007501618A (ja) * | 2003-08-08 | 2007-02-01 | アバニール・ファーマシューティカルズ | タンパク質輸送の選択的薬理学的阻害、および関連した、ヒト疾患を治療する方法 |
| CA2560896C (en) * | 2004-03-25 | 2013-06-18 | Janssen Pharmaceutica, N.V. | Imidazole compounds |
| MEP43308A (en) | 2006-05-09 | 2011-02-10 | Pfizer Prod Inc | Cycloalkylamino acid derivatives and pharmaceutical compositions thereof |
| PE20080948A1 (es) * | 2006-07-25 | 2008-09-10 | Irm Llc | Derivados de imidazol como moduladores de la senda de hedgehog |
| US9187485B2 (en) | 2007-02-02 | 2015-11-17 | Baylor College Of Medicine | Methods and compositions for the treatment of cancer and related hyperproliferative disorders |
| US9029408B2 (en) | 2008-06-16 | 2015-05-12 | Gtx, Inc. | Compounds for treatment of cancer |
| EP3289876B1 (en) | 2008-06-16 | 2022-07-20 | University of Tennessee Research Foundation | Compounds for treatment of cancer |
| US9447049B2 (en) | 2010-03-01 | 2016-09-20 | University Of Tennessee Research Foundation | Compounds for treatment of cancer |
| RU2506260C2 (ru) * | 2008-06-25 | 2014-02-10 | Энвиво Фармасьютикалз, Инк. | 1,2-дизамещенные гетероциклические соединения |
| RU2581367C2 (ru) | 2010-03-01 | 2016-04-20 | Джи Ти Икс, ИНК. | Соединения для лечения рака |
| AU2014345594B2 (en) * | 2013-11-05 | 2018-11-08 | Elanco Animal Health Gmbh | Substituted benzamides for the treatment of arthropods |
| US10328064B2 (en) | 2014-12-23 | 2019-06-25 | Fgh Biotech, Inc. | Compositions of fatostatin based heterocyclic compounds and uses thereof |
| MX2018013221A (es) | 2016-04-29 | 2019-06-24 | Fgh Biotech Inc | Compuestos de pirazol disustituidos para el tratamiento de enfermedades. |
| WO2018049080A1 (en) | 2016-09-07 | 2018-03-15 | Fgh Biotech, Inc. | Di-substituted pyrazole compounds for the treatment of diseases |
| US11090289B2 (en) | 2017-01-24 | 2021-08-17 | University Of Virginia Patent Foundation | Compositions and methods for blocking sodium channels |
| CN108191667B (zh) * | 2018-01-04 | 2021-03-26 | 利尔化学股份有限公司 | 2-硝基-4-三氟甲基苯甲酸甲酯的制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5206257A (en) * | 1987-03-05 | 1993-04-27 | May & Baker Limited | Pesticidal method using 2-phenylimidazole derivatives |
| JP2630432B2 (ja) * | 1987-08-24 | 1997-07-16 | コニカ株式会社 | 新規なシアンカプラーを含有するハロゲン化銀カラー写真感光材料 |
| JPH01224759A (ja) * | 1988-03-03 | 1989-09-07 | Konica Corp | 新規なシアンカプラーを含有するハロゲン化銀写真感光材料 |
| JPH01225949A (ja) * | 1988-03-04 | 1989-09-08 | Konica Corp | ハロゲン化銀写真感光材料 |
| JPH01262546A (ja) * | 1988-04-13 | 1989-10-19 | Konica Corp | 新規なシアンカプラーを含有するハロゲン化銀写真感光材料 |
| JPH0361946A (ja) * | 1989-07-29 | 1991-03-18 | Konica Corp | ハロゲン化銀カラー写真感光材料 |
| JPH03245140A (ja) * | 1990-02-23 | 1991-10-31 | Konica Corp | 新規なシアンカプラーを含有するハロゲン化銀写真感光材料 |
| US5646281A (en) * | 1990-12-28 | 1997-07-08 | Neurogen Corporation | Certain 4-piperidino- and piperazinomethyl-2-phenyl imidazole derivatives; dopamine receptor subtype specific ligands |
| JPH09304897A (ja) * | 1996-05-10 | 1997-11-28 | Konica Corp | 新規なシアンカプラーを含有するハロゲン化銀写真感光材料 |
| TW467902B (en) * | 1996-07-31 | 2001-12-11 | Bristol Myers Squibb Co | Diphenyl heterocycles as potassium channel modulators |
| CA2232467A1 (en) * | 1997-03-20 | 1998-09-20 | Richard A. Glennon | Imidazoles with serotonin receptor binding activity |
| GB0007405D0 (en) * | 2000-03-27 | 2000-05-17 | Smithkline Beecham Corp | Compounds |
-
2004
- 2004-04-09 EP EP04759360A patent/EP1613310A1/en not_active Withdrawn
- 2004-04-09 WO PCT/US2004/011010 patent/WO2004091610A1/en active Application Filing
- 2004-04-09 KR KR1020057019229A patent/KR20050120711A/ko not_active Application Discontinuation
- 2004-04-09 CA CA002521841A patent/CA2521841A1/en not_active Abandoned
- 2004-04-09 CN CNA2004800162918A patent/CN1826111A/zh active Pending
- 2004-04-09 JP JP2006509872A patent/JP2006522820A/ja active Pending
- 2004-04-09 AU AU2004229466A patent/AU2004229466A1/en not_active Abandoned
- 2004-04-09 US US10/821,667 patent/US20040229927A1/en not_active Abandoned
- 2004-04-09 PL PL378919A patent/PL378919A1/pl not_active Application Discontinuation
- 2004-04-09 RU RU2005134670/04A patent/RU2005134670A/ru not_active Application Discontinuation
- 2004-04-09 MX MXJL05000041A patent/MXJL05000041A/es unknown
- 2004-04-09 BR BRPI0409097-7A patent/BRPI0409097A/pt not_active IP Right Cessation
- 2004-04-12 TW TW093110069A patent/TW200503695A/zh unknown
- 2004-04-12 AR ARP040101207A patent/AR045886A1/es not_active Application Discontinuation
-
2005
- 2005-10-07 ZA ZA200508108A patent/ZA200508108B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1826111A (zh) | 2006-08-30 |
| CA2521841A1 (en) | 2004-10-28 |
| PL378919A1 (pl) | 2006-06-12 |
| US20040229927A1 (en) | 2004-11-18 |
| JP2006522820A (ja) | 2006-10-05 |
| BRPI0409097A (pt) | 2006-04-11 |
| WO2004091610A1 (en) | 2004-10-28 |
| AR045886A1 (es) | 2005-11-16 |
| KR20050120711A (ko) | 2005-12-22 |
| AU2004229466A1 (en) | 2004-10-28 |
| EP1613310A1 (en) | 2006-01-11 |
| RU2005134670A (ru) | 2006-06-10 |
| ZA200508108B (en) | 2007-03-28 |
| MXJL05000041A (es) | 2005-12-22 |
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