TW200418804A - New pyrazole compounds having antifungal activity - Google Patents
New pyrazole compounds having antifungal activity Download PDFInfo
- Publication number
- TW200418804A TW200418804A TW092128120A TW92128120A TW200418804A TW 200418804 A TW200418804 A TW 200418804A TW 092128120 A TW092128120 A TW 092128120A TW 92128120 A TW92128120 A TW 92128120A TW 200418804 A TW200418804 A TW 200418804A
- Authority
- TW
- Taiwan
- Prior art keywords
- compound
- phenyl
- group
- doc
- benzyloxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002296127 | 2002-10-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200418804A true TW200418804A (en) | 2004-10-01 |
Family
ID=32089230
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW092128120A TW200418804A (en) | 2002-10-09 | 2003-10-09 | New pyrazole compounds having antifungal activity |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JP4537855B2 (fr) |
| AU (1) | AU2003271117A1 (fr) |
| TW (1) | TW200418804A (fr) |
| WO (1) | WO2004033432A1 (fr) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102170787A (zh) * | 2008-10-03 | 2011-08-31 | 普罗蒂奥科技有限公司 | 用于治疗β-淀粉样蛋白病和突触核蛋白病的化合物、组合物和方法 |
| CN118184646A (zh) * | 2024-05-14 | 2024-06-14 | 苏州弘道新材料有限公司 | 用于光伏胶膜的吡唑啉衍生物光转换材料及其制备方法和应用 |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005033079A1 (fr) | 2003-09-30 | 2005-04-14 | Eisai Co., Ltd. | Agent antifongique a compose heterocyclique |
| JP2008516964A (ja) * | 2004-10-15 | 2008-05-22 | メモリー ファーマシューティカルス コーポレーション | ホスホジエステラーゼ４阻害剤としてのピラゾール誘導体 |
| JP4874958B2 (ja) | 2005-03-30 | 2012-02-15 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ピリジン誘導体を含有する抗真菌剤 |
| AU2006261845C1 (en) | 2005-06-27 | 2013-05-16 | Exelixis Patent Company Llc | Imidazole based LXR modulators |
| AU2006309762B2 (en) * | 2005-10-31 | 2010-02-25 | Eisai R&D Management Co., Ltd. | Heterocyclic substituted pyridine derivatives and antifungal agent containing same |
| TWI385169B (zh) | 2005-10-31 | 2013-02-11 | Eisai R&D Man Co Ltd | 經雜環取代之吡啶衍生物及含有彼之抗真菌劑 |
| WO2008035726A1 (fr) | 2006-09-21 | 2008-03-27 | Eisai R & D Management Co., Ltd. | Dérivé de pyridine substitué par un cycle hétéroaryle, et agent antifongique le comprenant |
| US20100105729A1 (en) * | 2006-10-06 | 2010-04-29 | Kalypsys, Inc. | Aryl-substituted heterocyclic pde4 inhibitors as anti-inflammatory agents |
| CN101679297B (zh) | 2006-12-08 | 2012-01-11 | 埃克塞利希斯股份有限公司 | Lxr和fxr调节剂 |
| TW200841879A (en) | 2007-04-27 | 2008-11-01 | Eisai R&D Man Co Ltd | Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same |
| KR20100015897A (ko) | 2007-04-27 | 2010-02-12 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 헤테로환 치환 피리딘 유도체의 염 또는 그의 결정 |
| US8513287B2 (en) | 2007-12-27 | 2013-08-20 | Eisai R&D Management Co., Ltd. | Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same |
| PT2307381T (pt) * | 2008-06-09 | 2021-03-15 | Univ Muenchen Ludwig Maximilians | Novas drogas para inibir a agregação de proteínas envolvidas em doenças relacionadas com a agregação de proteínas e/ou doenças neurodegenerativas |
| WO2010007943A1 (fr) * | 2008-07-17 | 2010-01-21 | 旭化成ファーマ株式会社 | Composé hétérocyclique azoté |
| US8188119B2 (en) | 2008-10-24 | 2012-05-29 | Eisai R&D Management Co., Ltd | Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same |
| CN101928246B (zh) * | 2009-10-16 | 2013-02-27 | 天津理工大学 | N-[(1-芳基-3-取代苯基-吡唑-4-基)次甲基]-2-羟基苯甲酰肼类化合物或其可药用盐及制备 |
| AU2012209696B2 (en) * | 2011-01-30 | 2015-09-03 | Meiji Seika Pharma Co., Ltd. | Topical antifungal agent |
| AR091934A1 (es) * | 2012-07-30 | 2015-03-11 | Meiji Seika Pharma Co Ltd | Parche para antidermatofitosis |
| AR092358A1 (es) * | 2012-07-30 | 2015-04-15 | Meiji Seika Pharma Co Ltd | Agente liquido topico para el tratamiento de la dermatofitosis |
| CN107857757A (zh) * | 2012-08-16 | 2018-03-30 | 詹森药业有限公司 | 作为n型钙通道阻滞剂的取代的吡唑 |
| US9453002B2 (en) | 2013-08-16 | 2016-09-27 | Janssen Pharmaceutica Nv | Substituted imidazoles as N-type calcium channel blockers |
| US10562858B2 (en) | 2014-08-13 | 2020-02-18 | Meiji Seika Pharma Co., Ltd. | Crystalline anti-trichophyton agents and preparation process thereof |
| CN104313064A (zh) * | 2014-10-01 | 2015-01-28 | 青岛科技大学 | 一种细胞法生产手性溴苯基丙酸甲酯的方法 |
| CN112119063B (zh) | 2018-05-18 | 2023-10-17 | 富士胶片株式会社 | 3-二氟甲基吡唑化合物的制造方法及3-二氟甲基吡唑-4-羧酸化合物的制造方法以及吡唑烷化合物 |
| CN111072643B (zh) * | 2019-12-25 | 2021-01-19 | 西华大学 | 4,5-二氢吡唑类化合物及其在农药中的应用 |
| CN111018848B (zh) * | 2019-12-25 | 2020-12-15 | 西华大学 | 1,3,5-三取代-4,5-二氢吡唑衍生物及其在农药中的应用 |
| CN110981864B (zh) * | 2019-12-25 | 2021-01-29 | 西华大学 | N-(4-氟苯基)-4,5-二氢吡唑类化合物及其在农药中的应用 |
| CN111039933B (zh) * | 2019-12-25 | 2021-03-02 | 西华大学 | 5-杂环取代的吡唑类化合物及其在农药中的应用 |
| CN110938062B (zh) * | 2019-12-25 | 2021-01-19 | 西华大学 | 3-(4-氯苯基)-4,5-二氢吡唑衍生物及其在农药中的应用 |
| CN111018845B (zh) * | 2019-12-25 | 2020-12-15 | 西华大学 | 3-(4-甲氧苯基)吡唑类化合物及其在农药中的应用 |
| CN112778208A (zh) * | 2021-01-08 | 2021-05-11 | 中南民族大学 | 一类二氢吡唑类MurA酶抑制剂分子及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2104932A1 (en) * | 1970-09-08 | 1972-04-28 | Ferlux | O-hydroxyphenyl pyrazoles - hypocholesterolemics anti inflammatories analgesics etc |
| US4170464A (en) * | 1974-10-25 | 1979-10-09 | American Cyanamid Company | Herbicidal combinations |
| IL91418A (en) * | 1988-09-01 | 1997-11-20 | Rhone Poulenc Agrochimie | (hetero) cyclic amide derivatives, process for their preparation and fungicidal compositions containing them |
| CN1231440C (zh) * | 1998-01-28 | 2005-12-14 | 盐野义制药株式会社 | 新的三环化合物 |
-
2003
- 2003-10-08 JP JP2004542837A patent/JP4537855B2/ja not_active Expired - Fee Related
- 2003-10-08 AU AU2003271117A patent/AU2003271117A1/en not_active Abandoned
- 2003-10-08 WO PCT/JP2003/012856 patent/WO2004033432A1/fr active Application Filing
- 2003-10-09 TW TW092128120A patent/TW200418804A/zh unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102170787A (zh) * | 2008-10-03 | 2011-08-31 | 普罗蒂奥科技有限公司 | 用于治疗β-淀粉样蛋白病和突触核蛋白病的化合物、组合物和方法 |
| CN102170787B (zh) * | 2008-10-03 | 2014-11-12 | 普罗蒂奥科技有限公司 | 用于治疗β-淀粉样蛋白病和突触核蛋白病的化合物、组合物和方法 |
| CN118184646A (zh) * | 2024-05-14 | 2024-06-14 | 苏州弘道新材料有限公司 | 用于光伏胶膜的吡唑啉衍生物光转换材料及其制备方法和应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003271117A1 (en) | 2004-05-04 |
| WO2004033432A1 (fr) | 2004-04-22 |
| JPWO2004033432A1 (ja) | 2006-02-09 |
| JP4537855B2 (ja) | 2010-09-08 |
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