TW200400035A - Novel compounds - Google Patents
Novel compounds Download PDFInfo
- Publication number
- TW200400035A TW200400035A TW092106766A TW92106766A TW200400035A TW 200400035 A TW200400035 A TW 200400035A TW 092106766 A TW092106766 A TW 092106766A TW 92106766 A TW92106766 A TW 92106766A TW 200400035 A TW200400035 A TW 200400035A
- Authority
- TW
- Taiwan
- Prior art keywords
- methyl
- formula
- compound
- urea
- morpholin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0207434A GB0207434D0 (en) | 2002-03-28 | 2002-03-28 | Novel compounds |
| GB0301608A GB0301608D0 (en) | 2003-01-24 | 2003-01-24 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200400035A true TW200400035A (en) | 2004-01-01 |
Family
ID=28676494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW092106766A TW200400035A (en) | 2002-03-28 | 2003-03-26 | Novel compounds |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7622464B2 (enExample) |
| EP (1) | EP1487828B1 (enExample) |
| JP (1) | JP4465195B2 (enExample) |
| KR (1) | KR20040093488A (enExample) |
| CN (1) | CN1656092A (enExample) |
| AR (1) | AR040403A1 (enExample) |
| AT (1) | ATE413399T1 (enExample) |
| AU (1) | AU2003226757A1 (enExample) |
| BR (1) | BR0308780A (enExample) |
| CA (1) | CA2480106A1 (enExample) |
| CY (1) | CY1108652T1 (enExample) |
| DE (1) | DE60324535D1 (enExample) |
| DK (1) | DK1487828T3 (enExample) |
| ES (1) | ES2315519T3 (enExample) |
| IL (1) | IL164047A0 (enExample) |
| IS (1) | IS7444A (enExample) |
| MX (1) | MXPA04009459A (enExample) |
| NO (1) | NO20044448L (enExample) |
| PT (1) | PT1487828E (enExample) |
| RU (1) | RU2004127928A (enExample) |
| SI (1) | SI1487828T1 (enExample) |
| TW (1) | TW200400035A (enExample) |
| WO (1) | WO2003082861A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1615878B1 (en) | 2003-01-14 | 2012-04-04 | Cytokinetics, Inc. | Compounds, compositions and methods of treatment for heart failure |
| EP1608319A4 (en) | 2003-04-03 | 2007-02-28 | Univ California | IMPROVED HEMMER FOR SOLUBLE EPOXY HYDROLASE |
| CA2559665A1 (en) | 2004-03-16 | 2005-09-29 | The Regents Of The University Of California | Reducing nephropathy with inhibitors of soluble epoxide hydrolase and epoxyeicosanoids |
| RS53600B1 (sr) | 2004-06-17 | 2015-02-27 | Cytokinetics, Inc. | Jedinjenja, preparati i metode |
| AU2005261740A1 (en) * | 2004-07-08 | 2006-01-19 | Novo Nordisk A/S | Polypeptide protracting tags comprising a tetrazole moiety |
| US7176222B2 (en) | 2004-07-27 | 2007-02-13 | Cytokinetics, Inc. | Syntheses of ureas |
| PL1801108T3 (pl) | 2004-09-08 | 2013-04-30 | Mitsubishi Tanabe Pharma Corp | Związki morfolinowe do leczenia stanów zapalnych |
| CN101084216B (zh) | 2004-10-20 | 2011-09-14 | 加利福尼亚大学董事会 | 可溶性环氧化物水解酶的改进抑制剂 |
| US7538223B2 (en) | 2005-08-04 | 2009-05-26 | Cytokinetics, Inc. | Compounds, compositions and methods |
| US7825120B2 (en) | 2005-12-15 | 2010-11-02 | Cytokinetics, Inc. | Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas |
| AR058347A1 (es) | 2005-12-15 | 2008-01-30 | Cytokinetics Inc | Entidades quimias composiciones y metodos |
| WO2007078815A2 (en) | 2005-12-16 | 2007-07-12 | Cytokinetics, Inc. | Certain chemical entities, compositions, and methods |
| US7989455B2 (en) | 2005-12-19 | 2011-08-02 | Cytokinetics, Inc. | Compounds, compositions and methods |
| AR059826A1 (es) | 2006-03-13 | 2008-04-30 | Univ California | Inhibidores de urea conformacionalmente restringidos de epoxido hidrolasa soluble |
| KR101669432B1 (ko) | 2007-08-27 | 2016-10-26 | 다트 뉴로사이언스 (케이만) 엘티디. | 치료적 이속사졸 화합물 |
| WO2012054093A2 (en) | 2010-01-29 | 2012-04-26 | The Regents Of The University Of California | Acyl piperidine inhibitors of soluble epoxide hydrolase |
| RU2512293C1 (ru) * | 2012-12-13 | 2014-04-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" | Способ получения этил 1,2,4-оксадиазол-5-карбоксилатов |
| CN107362362B (zh) * | 2017-07-20 | 2019-01-01 | 复旦大学 | Sirt1抑制剂在预防和治疗放射引起的肠道疾病中的应用 |
| CA3187052A1 (en) * | 2020-07-29 | 2022-02-03 | Eddy Sotelo Perez | Functionalized isonitriles and products, preparation and uses thereof |
| CA3190593A1 (en) * | 2020-08-03 | 2022-02-10 | Global Blood Therapeutics, Inc. | Urea derivatives as pyruvate kinase activators |
| CN119330881A (zh) * | 2024-09-06 | 2025-01-21 | 苏州汉德创宏生化科技有限公司 | 一种3-氨甲基-1-h吡唑的合成方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4851526A (en) | 1987-09-04 | 1989-07-25 | Schering A.G. | 1-(4-Substituted phenyl)-1H-imidazoles compounds |
| JP3087763B2 (ja) * | 1990-11-30 | 2000-09-11 | 三井化学株式会社 | 新規な複素環式化合物およびそれを含有する医薬組成物 |
| US5219856A (en) | 1992-04-06 | 1993-06-15 | E. I. Du Pont De Nemours And Company | Angiotensin-II receptor blocking, heterocycle substituted imidazoles |
| AU694226B2 (en) | 1994-05-19 | 1998-07-16 | Merck Sharp & Dohme Limited | Piperazine, piperidine and tetrahydropyridine derivatives ofindol-3-ylalkyl as 5-HT1D-alpha agonists |
| EP0772611A1 (de) | 1994-07-20 | 1997-05-14 | Byk Gulden Lomberg Chemische Fabrik GmbH | Piperazinothiopyridine zur bekämpfung von helicobacter-bakterien |
| US5654316A (en) | 1995-06-06 | 1997-08-05 | Schering Corporation | Piperidine derivatives as neurokinin antagonists |
| AU2980797A (en) | 1996-06-11 | 1998-01-07 | Yoshitomi Pharmaceutical Industries, Ltd. | Fused heterocyclic compounds and medicinal uses thereof |
| US5919776A (en) * | 1996-12-20 | 1999-07-06 | Merck & Co., Inc. | Substituted aminoquinolines as modulators of chemokine receptor activity |
| US6207665B1 (en) | 1997-06-12 | 2001-03-27 | Schering Aktiengesellschaft | Piperazine derivatives and their use as anti-inflammatory agents |
| IT1293807B1 (it) | 1997-08-01 | 1999-03-10 | Recordati Chem Pharm | Derivati 1- (n-fenilaminoalchil) piperazinici sostituiti alla posizione 2 dell'anello fenilico |
| US6031097A (en) | 1997-10-27 | 2000-02-29 | Neurogen Corporation | 1-(N-(arylalkylaminoalkyl) aminoisoquinolines; a new class of dopamine receptor subtype specific ligands |
| AU1122399A (en) | 1997-10-27 | 1999-05-17 | Neurogen Corporation | Novel 1-(n'-(arylalkylaminoalkyl))aminoisoindoles; a new class of dopamine receptor subtype specific ligands |
| HK1038749A1 (zh) | 1998-09-30 | 2002-03-28 | 纽罗根公司 | 2-哌嗪烷基氨苯并吡咯衍生物:多巴胺受体亚型特异配体 |
| BR0114323A (pt) | 2000-09-29 | 2003-07-01 | Glaxo Group Ltd | Composto ou um seu sal ou solvato farmaceuticamente aceitável, composição farmacêutica, uso do composto ou de um seu sal ou solvato farmaceuticamente aceitável, método de tratamento ou profilaxia de doenças inflamatórias, e, processo para preparar o composto |
| BR0114321A (pt) * | 2000-09-29 | 2003-07-01 | Glaxo Group Ltd | Composto, composição farmacêutica, uso de um composto, método de tratamento ou profilaxia de doenças inflamatórias, e, processo para preparar um composto |
-
2003
- 2003-03-26 TW TW092106766A patent/TW200400035A/zh unknown
- 2003-03-27 CA CA002480106A patent/CA2480106A1/en not_active Abandoned
- 2003-03-27 SI SI200331471T patent/SI1487828T1/sl unknown
- 2003-03-27 MX MXPA04009459A patent/MXPA04009459A/es unknown
- 2003-03-27 BR BR0308780-8A patent/BR0308780A/pt not_active Application Discontinuation
- 2003-03-27 AT AT03745294T patent/ATE413399T1/de active
- 2003-03-27 WO PCT/EP2003/003335 patent/WO2003082861A2/en not_active Ceased
- 2003-03-27 JP JP2003580326A patent/JP4465195B2/ja not_active Expired - Lifetime
- 2003-03-27 PT PT03745294T patent/PT1487828E/pt unknown
- 2003-03-27 DE DE60324535T patent/DE60324535D1/de not_active Expired - Lifetime
- 2003-03-27 KR KR10-2004-7015398A patent/KR20040093488A/ko not_active Withdrawn
- 2003-03-27 DK DK03745294T patent/DK1487828T3/da active
- 2003-03-27 AR AR20030101081A patent/AR040403A1/es unknown
- 2003-03-27 CN CNA038115506A patent/CN1656092A/zh active Pending
- 2003-03-27 US US10/509,162 patent/US7622464B2/en active Active
- 2003-03-27 ES ES03745294T patent/ES2315519T3/es not_active Expired - Lifetime
- 2003-03-27 IL IL16404703A patent/IL164047A0/xx unknown
- 2003-03-27 EP EP03745294A patent/EP1487828B1/en not_active Expired - Lifetime
- 2003-03-27 RU RU2004127928/04A patent/RU2004127928A/ru not_active Application Discontinuation
- 2003-03-27 AU AU2003226757A patent/AU2003226757A1/en not_active Abandoned
-
2004
- 2004-09-13 IS IS7444A patent/IS7444A/is unknown
- 2004-10-19 NO NO20044448A patent/NO20044448L/no not_active Application Discontinuation
-
2008
- 2008-12-19 CY CY20081101474T patent/CY1108652T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60324535D1 (de) | 2008-12-18 |
| CA2480106A1 (en) | 2003-10-09 |
| WO2003082861A3 (en) | 2004-03-11 |
| SI1487828T1 (sl) | 2009-04-30 |
| IS7444A (is) | 2004-09-13 |
| KR20040093488A (ko) | 2004-11-05 |
| BR0308780A (pt) | 2004-12-28 |
| JP4465195B2 (ja) | 2010-05-19 |
| IL164047A0 (en) | 2005-12-18 |
| ATE413399T1 (de) | 2008-11-15 |
| MXPA04009459A (es) | 2005-01-25 |
| PT1487828E (pt) | 2009-01-06 |
| NO20044448L (no) | 2004-10-26 |
| US20060063765A1 (en) | 2006-03-23 |
| US7622464B2 (en) | 2009-11-24 |
| RU2004127928A (ru) | 2005-06-27 |
| CY1108652T1 (el) | 2014-08-13 |
| CN1656092A (zh) | 2005-08-17 |
| WO2003082861A2 (en) | 2003-10-09 |
| JP2005526815A (ja) | 2005-09-08 |
| AU2003226757A1 (en) | 2003-10-13 |
| DK1487828T3 (da) | 2009-02-02 |
| EP1487828B1 (en) | 2008-11-05 |
| AR040403A1 (es) | 2005-04-06 |
| EP1487828A2 (en) | 2004-12-22 |
| ES2315519T3 (es) | 2009-04-01 |
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