TR201911258T4 - 3D in vitro çift fazlı kıkırdak-kemik yapısı. - Google Patents
3D in vitro çift fazlı kıkırdak-kemik yapısı. Download PDFInfo
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- TR201911258T4 TR201911258T4 TR2019/11258T TR201911258T TR201911258T4 TR 201911258 T4 TR201911258 T4 TR 201911258T4 TR 2019/11258 T TR2019/11258 T TR 2019/11258T TR 201911258 T TR201911258 T TR 201911258T TR 201911258 T4 TR201911258 T4 TR 201911258T4
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- Prior art keywords
- cartilage
- artificial
- bone structure
- tissue layer
- bone
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- A—HUMAN NECESSITIES
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/10—Ceramics or glasses
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- A—HUMAN NECESSITIES
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
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- A—HUMAN NECESSITIES
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
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- A—HUMAN NECESSITIES
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
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- C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
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- A61L2430/00—Materials or treatment for tissue regeneration
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12157484.2A EP2634251A1 (en) | 2012-02-29 | 2012-02-29 | 3D in vitro bi-phasic cartilage-bone construct |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201911258T4 true TR201911258T4 (tr) | 2019-08-21 |
Family
ID=48083111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2019/11258T TR201911258T4 (tr) | 2012-02-29 | 2013-02-28 | 3D in vitro çift fazlı kıkırdak-kemik yapısı. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9856458B2 (enExample) |
| EP (2) | EP2634251A1 (enExample) |
| JP (1) | JP2015511482A (enExample) |
| CN (1) | CN104204191B (enExample) |
| DK (1) | DK2834348T3 (enExample) |
| ES (1) | ES2739201T3 (enExample) |
| HU (1) | HUE044561T2 (enExample) |
| RU (1) | RU2615439C2 (enExample) |
| SG (2) | SG11201403907VA (enExample) |
| TR (1) | TR201911258T4 (enExample) |
| WO (1) | WO2013127921A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| EP3149156B1 (en) | 2014-05-28 | 2021-02-17 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
| JP6804438B2 (ja) | 2014-10-17 | 2020-12-23 | チルドレンズ ホスピタル メディカル センター | 多能性幹細胞を使用するヒト小腸のin vivoモデル、並びにそれを作製、及び使用する方法 |
| US9238090B1 (en) | 2014-12-24 | 2016-01-19 | Fettech, Llc | Tissue-based compositions |
| US20180258400A1 (en) * | 2015-09-15 | 2018-09-13 | Agency For Science, Technology And Research (A*Star) | Derivation of liver organoids from human pluripotent stem cells |
| KR101733137B1 (ko) * | 2015-12-30 | 2017-05-08 | (주)엑셀세라퓨틱스 | 연골조직 제조를 위한 3차원 오가노이드 블록 제작 방법 |
| CN105754856B (zh) * | 2016-04-12 | 2018-06-22 | 中国航天员科研训练中心 | 一种抽屉式三维类血管化组织培养器官芯片及其构建方法 |
| CN105754855B (zh) * | 2016-04-12 | 2018-08-21 | 中国航天员科研训练中心 | 一种流加式两层细胞共培养器官芯片 |
| EP4177335A1 (en) | 2016-05-05 | 2023-05-10 | Children's Hospital Medical Center | Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same |
| KR101836475B1 (ko) * | 2016-08-02 | 2018-03-08 | 아주대학교산학협력단 | 연골 재생용 조성물 및 이의 제조방법 |
| EP3534976A4 (en) | 2016-11-04 | 2020-09-16 | Children's Hospital Medical Center | PATHOLOGICAL MODELS OF HEPATIC ORGANOIDS AND ASSOCIATED METHODS OF MANUFACTURE AND USE |
| EP3548507A4 (en) | 2016-12-05 | 2020-07-15 | Children's Hospital Medical Center | COLON ORGANOIDS AND PROCESSES FOR THE PREPARATION AND USE THEREOF |
| EP3609997A4 (en) | 2017-04-14 | 2021-03-03 | Children's Hospital Medical Center | COMPOSITIONS OF STEM CELLS FROM MULTIPLE DONOR CELLS AND THEIR PREPARATION PROCEDURES |
| EP3694603A4 (en) | 2017-10-10 | 2021-07-14 | Children's Hospital Medical Center | ESOPHAGUS TISSUE AND / OR ORGANOID COMPOSITIONS AND METHOD FOR MANUFACTURING THEREOF |
| US12379372B2 (en) | 2017-12-21 | 2025-08-05 | Children's Hospital Medical Center | Digitalized human organoids and methods of using same |
| EP3768334A4 (en) * | 2018-03-21 | 2021-12-22 | Natural Enamel, LLC | DENSIFICATION AND STRUCTURAL ALIGNMENT OF BIOMINERALIZED MATTER |
| KR102887406B1 (ko) | 2018-07-26 | 2025-11-19 | 칠드런즈 호스피탈 메디칼 센터 | 간-담도-췌장 조직 및 이를 제조하는 방법 |
| WO2020056158A1 (en) | 2018-09-12 | 2020-03-19 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| JP2022514298A (ja) * | 2018-12-19 | 2022-02-10 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | オルガノイドおよびその組織を作製および使用するための方法 |
| CN111494711B (zh) * | 2019-01-31 | 2023-06-23 | 华东理工大学 | 干细胞发生器产生的干细胞用于治疗造血损伤 |
| CN117716021A (zh) * | 2021-08-31 | 2024-03-15 | 公立大学法人横滨市立大学 | 可成型且无需支架的软骨组织的制作方法 |
| CN115369079B (zh) * | 2022-06-22 | 2023-10-13 | 广东省科学院生物与医学工程研究所 | 一种组合物及其在制备细胞薄膜中的应用 |
| CN115671397B (zh) * | 2022-11-10 | 2023-10-13 | 上海大学 | 一种多肽和双生长因子梯度分布的含细胞骨软骨支架及其制备方法和应用 |
| CN118147057B (zh) * | 2024-02-21 | 2025-10-03 | 上海交通大学医学院附属第九人民医院 | 一种人源骨髓类器官及其构建方法和应用 |
| CN119060939B (zh) * | 2024-08-29 | 2025-08-22 | 北京大学口腔医学院 | 一种骨类器官及其构建方法与用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4414644A1 (de) | 1993-10-29 | 1995-05-04 | Bosch Gmbh Robert | Fahrzeugsicherungsanordnung |
| US7888119B2 (en) * | 2005-10-14 | 2011-02-15 | University Of Central Florida Research Foundation, Inc. | Tissue substitutes comprising stem cells and reduced ceria |
| US20100167401A1 (en) * | 2007-03-19 | 2010-07-01 | Vasif Hasirci | Stacked, patterned biomaterials and/or tissue engineering scaffolds |
| CN102257124B (zh) | 2008-06-04 | 2014-12-03 | 蒂斯由斯股份有限公司 | 芯片上器官装置 |
| EP2403550A2 (en) * | 2008-11-24 | 2012-01-11 | BioE LLC | Implantable compositions for repairing osteochondral defects |
| PT2542663E (pt) | 2010-08-06 | 2014-10-07 | Tissuse Gmbh | Sistema de circulação |
-
2012
- 2012-02-29 EP EP12157484.2A patent/EP2634251A1/en not_active Withdrawn
-
2013
- 2013-02-28 US US14/381,216 patent/US9856458B2/en active Active
- 2013-02-28 WO PCT/EP2013/054030 patent/WO2013127921A1/en not_active Ceased
- 2013-02-28 JP JP2014559215A patent/JP2015511482A/ja active Pending
- 2013-02-28 CN CN201380011832.7A patent/CN104204191B/zh active Active
- 2013-02-28 SG SG11201403907VA patent/SG11201403907VA/en unknown
- 2013-02-28 TR TR2019/11258T patent/TR201911258T4/tr unknown
- 2013-02-28 SG SG10201607179SA patent/SG10201607179SA/en unknown
- 2013-02-28 RU RU2014136268A patent/RU2615439C2/ru active
- 2013-02-28 DK DK13715147.8T patent/DK2834348T3/da active
- 2013-02-28 ES ES13715147T patent/ES2739201T3/es active Active
- 2013-02-28 EP EP13715147.8A patent/EP2834348B1/en active Active
- 2013-02-28 HU HUE13715147 patent/HUE044561T2/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20150093428A1 (en) | 2015-04-02 |
| WO2013127921A1 (en) | 2013-09-06 |
| SG10201607179SA (en) | 2016-10-28 |
| JP2015511482A (ja) | 2015-04-20 |
| EP2834348B1 (en) | 2019-05-08 |
| US9856458B2 (en) | 2018-01-02 |
| EP2634251A1 (en) | 2013-09-04 |
| CN104204191B (zh) | 2017-02-22 |
| ES2739201T3 (es) | 2020-01-29 |
| SG11201403907VA (en) | 2014-09-26 |
| RU2014136268A (ru) | 2016-03-27 |
| EP2834348A1 (en) | 2015-02-11 |
| RU2615439C2 (ru) | 2017-04-04 |
| HK1201072A1 (en) | 2015-08-21 |
| CN104204191A (zh) | 2014-12-10 |
| DK2834348T3 (da) | 2019-08-05 |
| HUE044561T2 (hu) | 2019-11-28 |
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