ES2739201T3 - Construcción 3D in vitro bifásica cartílago-hueso - Google Patents

Construcción 3D in vitro bifásica cartílago-hueso Download PDF

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Publication number
ES2739201T3
ES2739201T3 ES13715147T ES13715147T ES2739201T3 ES 2739201 T3 ES2739201 T3 ES 2739201T3 ES 13715147 T ES13715147 T ES 13715147T ES 13715147 T ES13715147 T ES 13715147T ES 2739201 T3 ES2739201 T3 ES 2739201T3
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Prior art keywords
bone
cells
vitro
culture
cartilage
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English (en)
Spanish (es)
Inventor
Mark Rosowski
Shirin Fatehi-Varkani
Roland Lauster
Uwe Marx
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TISSUSE GmbH
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TISSUSE GmbH
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/10—Ceramics or glasses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
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    • A61L27/3847—Bones
    • A—HUMAN NECESSITIES
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
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    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
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    • C12N5/0602—Vertebrate cells
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    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
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    • A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
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    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
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ES13715147T 2012-02-29 2013-02-28 Construcción 3D in vitro bifásica cartílago-hueso Active ES2739201T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12157484.2A EP2634251A1 (en) 2012-02-29 2012-02-29 3D in vitro bi-phasic cartilage-bone construct
PCT/EP2013/054030 WO2013127921A1 (en) 2012-02-29 2013-02-28 3d in vitro bi-phasic cartilage-bone construct

Publications (1)

Publication Number Publication Date
ES2739201T3 true ES2739201T3 (es) 2020-01-29

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ES13715147T Active ES2739201T3 (es) 2012-02-29 2013-02-28 Construcción 3D in vitro bifásica cartílago-hueso

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Country Link
US (1) US9856458B2 (enExample)
EP (2) EP2634251A1 (enExample)
JP (1) JP2015511482A (enExample)
CN (1) CN104204191B (enExample)
DK (1) DK2834348T3 (enExample)
ES (1) ES2739201T3 (enExample)
HU (1) HUE044561T2 (enExample)
RU (1) RU2615439C2 (enExample)
SG (2) SG11201403907VA (enExample)
TR (1) TR201911258T4 (enExample)
WO (1) WO2013127921A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011140441A2 (en) 2010-05-06 2011-11-10 Children's Hospital Medical Center Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
EP3149156B1 (en) 2014-05-28 2021-02-17 Children's Hospital Medical Center Methods and systems for converting precursor cells into gastric tissues through directed differentiation
JP6804438B2 (ja) 2014-10-17 2020-12-23 チルドレンズ ホスピタル メディカル センター 多能性幹細胞を使用するヒト小腸のｉｎ ｖｉｖｏモデル、並びにそれを作製、及び使用する方法
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US20180258400A1 (en) * 2015-09-15 2018-09-13 Agency For Science, Technology And Research (A*Star) Derivation of liver organoids from human pluripotent stem cells
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