JP2015511482A - ３ｄインビトロ二相性軟骨構造物 - Google Patents

３ｄインビトロ二相性軟骨構造物 Download PDF

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Publication number
JP2015511482A
JP2015511482A JP2014559215A JP2014559215A JP2015511482A JP 2015511482 A JP2015511482 A JP 2015511482A JP 2014559215 A JP2014559215 A JP 2014559215A JP 2014559215 A JP2014559215 A JP 2014559215A JP 2015511482 A JP2015511482 A JP 2015511482A
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Prior art keywords
cells
cartilage
culture
tissue
artificial
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JP2014559215A
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Japanese (ja)
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JP2015511482A5 (enExample
Inventor
ロソウスキー，マルク
ファテヒ−ヴァルカニ，シリン
ラウスター，ローラント
マルクス，ウーヴェ
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Tissuse GmbH
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Tissuse GmbH
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/10—Ceramics or glasses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3847—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage
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    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • A—HUMAN NECESSITIES
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    • A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
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  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
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  • Developmental Biology & Embryology (AREA)
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JP2014559215A 2012-02-29 2013-02-28 ３ｄインビトロ二相性軟骨構造物 Pending JP2015511482A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12157484.2A EP2634251A1 (en) 2012-02-29 2012-02-29 3D in vitro bi-phasic cartilage-bone construct
EP12157484.2 2012-02-29
PCT/EP2013/054030 WO2013127921A1 (en) 2012-02-29 2013-02-28 3d in vitro bi-phasic cartilage-bone construct

Publications (2)

Publication Number Publication Date
JP2015511482A true JP2015511482A (ja) 2015-04-20
JP2015511482A5 JP2015511482A5 (enExample) 2016-03-10

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JP2014559215A Pending JP2015511482A (ja) 2012-02-29 2013-02-28 ３ｄインビトロ二相性軟骨構造物

Country Status (11)

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US (1) US9856458B2 (enExample)
EP (2) EP2634251A1 (enExample)
JP (1) JP2015511482A (enExample)
CN (1) CN104204191B (enExample)
DK (1) DK2834348T3 (enExample)
ES (1) ES2739201T3 (enExample)
HU (1) HUE044561T2 (enExample)
RU (1) RU2615439C2 (enExample)
SG (2) SG11201403907VA (enExample)
TR (1) TR201911258T4 (enExample)
WO (1) WO2013127921A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019505346A (ja) * 2015-12-30 2019-02-28 エックスセル セラピューティックス インク．Ｘｃｅｌｌ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． ３ｄ軟骨オルガノイドブロックを調製するための方法
WO2023032441A1 (ja) * 2021-08-31 2023-03-09 公立大学法人横浜市立大学 造形可能かつ足場不要な軟骨組織の創出法

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