TR201902609T4 - İbandronat polimorf A nın tıbbi kullanımı. - Google Patents

İbandronat polimorf A nın tıbbi kullanımı. Download PDF

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Publication number
TR201902609T4
TR201902609T4 TR2019/02609T TR201902609T TR201902609T4 TR 201902609 T4 TR201902609 T4 TR 201902609T4 TR 2019/02609 T TR2019/02609 T TR 2019/02609T TR 201902609 T TR201902609 T TR 201902609T TR 201902609 T4 TR201902609 T4 TR 201902609T4
Authority
TR
Turkey
Prior art keywords
medical use
ibandronic acid
acid polymorph
polymorph
hydroxypropane
Prior art date
Application number
TR2019/02609T
Other languages
English (en)
Inventor
Sattelkau Tim
Junghans Bernd
Eiermann Uwe
Knipp Bernhard
Original Assignee
Atnahs Pharma Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36090730&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR201902609(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Atnahs Pharma Uk Ltd filed Critical Atnahs Pharma Uk Ltd
Publication of TR201902609T4 publication Critical patent/TR201902609T4/tr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Mevcut buluş, aşağıdaki formül ile 3-(N-metil-N-pentil) amino-1-hidroksipropan-11-difosfonik asit monosodyum tuzu monohidratın (İbandronat) yeni bir polimorf kristal formu ile ilgilidir.
TR2019/02609T 2005-02-01 2006-01-24 İbandronat polimorf A nın tıbbi kullanımı. TR201902609T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05100686 2005-02-01

Publications (1)

Publication Number Publication Date
TR201902609T4 true TR201902609T4 (tr) 2019-03-21

Family

ID=36090730

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/02609T TR201902609T4 (tr) 2005-02-01 2006-01-24 İbandronat polimorf A nın tıbbi kullanımı.

Country Status (25)

Country Link
US (1) US7714158B2 (tr)
EP (2) EP2662380B1 (tr)
JP (2) JP5828608B2 (tr)
KR (1) KR100908529B1 (tr)
CN (1) CN101111504B (tr)
AR (1) AR053012A1 (tr)
AU (1) AU2006210009B2 (tr)
BR (1) BRPI0607092A2 (tr)
CA (1) CA2594802C (tr)
CY (1) CY1121703T1 (tr)
DK (1) DK2662380T3 (tr)
ES (2) ES2478302T3 (tr)
HU (1) HUE042316T2 (tr)
IL (1) IL184562A (tr)
LT (1) LT2662380T (tr)
MX (1) MX2007009107A (tr)
NO (1) NO20073723L (tr)
PL (1) PL2662380T3 (tr)
PT (1) PT2662380T (tr)
RU (1) RU2368617C2 (tr)
SI (1) SI2662380T1 (tr)
TR (1) TR201902609T4 (tr)
TW (1) TWI374889B (tr)
WO (1) WO2006081963A1 (tr)
ZA (1) ZA200706168B (tr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1713489E (pt) 2004-08-23 2011-03-03 Teva Pharma Forma cristalina de ibandronato de sódio e processos para a sua preparação
SI1848727T1 (sl) * 2005-02-01 2015-09-30 F. Hoffmann-La Roche Ag Polimorf b ibandronata
WO2007074475A2 (en) * 2005-12-27 2007-07-05 Natco Pharma Limited Novel polymorphic forms of ibandronate
CA2656053A1 (en) * 2006-07-03 2008-01-10 Generics [Uk] Limited Novel process for the preparation of bisphosphonic acids
EP2009016A3 (en) * 2006-11-16 2009-02-25 Teva Pharmaceutical Industries Ltd Process for preparing crystalline form of ibandronate sodium
CA2570949A1 (en) * 2006-12-12 2008-06-12 Apotex Pharmachem Inc. Ibandronate sodium propylene glycol solvate and processes for the preparation thereof
PL2144919T3 (pl) * 2007-04-11 2016-05-31 Hoffmann La Roche Wieloetapowa synteza ibandronianu
KR20100014728A (ko) 2007-04-19 2010-02-10 닥터 레디스 레보러터리즈 리미티드 이반드로네이트 나트륨 다형태
WO2009020483A1 (en) * 2007-08-09 2009-02-12 Teva Pharmaceutical Industries Ltd. Crystalline forms of ibandronate sodium
EP2128166A1 (en) 2008-05-20 2009-12-02 Chemo Ibérica, S.A. Polymorphic forms of Ibandronate sodium and processes for preparation thereof
EP2180003A1 (en) 2008-10-21 2010-04-28 Zentiva, k.s. Preparation of ibandronate trisodium
EP2609101B1 (en) 2010-07-14 2015-01-28 Pharmathen S.A. Process for the preparation of 3-(n-methyl-n-pentyl)amino-1-hydroxypropane-1,1-diphosphonic acid salt or derivatives thereof
TR201200588A2 (tr) 2012-01-18 2012-07-23 Koçak Farma İlaç Ve Ki̇mya Sanayi̇ Anoni̇m Şi̇rketi̇ Sodyum ibandronat monohidrat polimorflarini ve polimorflu karışımlarını hazırlamak için prosesler.
KR20200085441A (ko) 2019-01-07 2020-07-15 엠에프씨 주식회사 이반드로네이트의 신규한 결정형 및 이의 제조방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
TW198039B (tr) * 1988-11-28 1993-01-11 Ciba Geigy Ag
IT1303672B1 (it) * 1998-07-28 2001-02-23 Nicox Sa Sali nitrati di farmaci attivi nei disordini ossei
EP0998932A1 (de) * 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Feste pharmazeutische Darreichungsform enthaltend Diphosphonsäure oder deren Salze und Verfahren zu ihrer Herstellung
DE69907495T2 (de) 1998-10-16 2004-05-06 Akzo Nobel N.V. (7alpha,17alpha)-17-hydroxy-7-methyl-19-nor-17-pregn-5-(10)-en-20-yn-3-on als reine verbindung
ATE303153T1 (de) * 1998-12-04 2005-09-15 Roche Diagnostics Gmbh Ibandroinsäure zur förderung der osseointegration der endoprothesen
US6677320B2 (en) 2000-01-20 2004-01-13 Hoffmann-La Roches Inc. Parenteral bisphosphonate composition with improved local tolerance
CN1404836A (zh) * 2001-09-14 2003-03-26 中生北方生物工程开发研究所 埃本膦酸钠作为预防和治疗骨质疏松症的药物的有效成分的应用
BR0308901A (pt) * 2002-05-10 2005-01-04 Hoffmann La Roche ácidos bisfosfÈnicos para tratamento e prevenção de osteoporose
SI1596870T2 (sl) * 2002-12-20 2011-07-29 Hoffmann La Roche Formulacija z visokim odmerkom ibandronata
WO2006002348A2 (en) 2004-06-23 2006-01-05 Teva Pharmaceutical Industies Ltd. Solid and crystalline ibandronic acid
PT1713489E (pt) 2004-08-23 2011-03-03 Teva Pharma Forma cristalina de ibandronato de sódio e processos para a sua preparação

Also Published As

Publication number Publication date
SI2662380T1 (sl) 2019-04-30
IL184562A0 (en) 2007-10-31
JP5828608B2 (ja) 2015-12-09
DK2662380T3 (en) 2019-03-18
RU2368617C2 (ru) 2009-09-27
CN101111504B (zh) 2011-12-21
NO20073723L (no) 2007-08-28
JP6039754B2 (ja) 2016-12-07
JP2015205907A (ja) 2015-11-19
WO2006081963A1 (en) 2006-08-10
RU2007132701A (ru) 2009-03-10
ZA200706168B (en) 2008-09-25
PT2662380T (pt) 2019-02-27
ES2478302T3 (es) 2014-07-21
PL2662380T3 (pl) 2019-05-31
KR20070100394A (ko) 2007-10-10
AU2006210009A1 (en) 2006-08-10
US7714158B2 (en) 2010-05-11
US20060172975A1 (en) 2006-08-03
JP2008529980A (ja) 2008-08-07
CN101111504A (zh) 2008-01-23
AR053012A1 (es) 2007-04-18
EP2662380A1 (en) 2013-11-13
EP1848728B1 (en) 2014-06-11
AU2006210009B2 (en) 2009-08-13
EP1848728A1 (en) 2007-10-31
TWI374889B (en) 2012-10-21
EP2662380B1 (en) 2018-11-21
BRPI0607092A2 (pt) 2009-08-04
TW200638939A (en) 2006-11-16
CA2594802A1 (en) 2006-08-10
CY1121703T1 (el) 2020-07-31
MX2007009107A (es) 2007-09-11
LT2662380T (lt) 2019-03-12
KR100908529B1 (ko) 2009-07-20
ES2712644T3 (es) 2019-05-14
HUE042316T2 (hu) 2019-06-28
IL184562A (en) 2015-11-30
CA2594802C (en) 2012-11-27

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