ZA200706168B - Ibandronate polymorph A - Google Patents
Ibandronate polymorph AInfo
- Publication number
- ZA200706168B ZA200706168B ZA200706168A ZA200706168A ZA200706168B ZA 200706168 B ZA200706168 B ZA 200706168B ZA 200706168 A ZA200706168 A ZA 200706168A ZA 200706168 A ZA200706168 A ZA 200706168A ZA 200706168 B ZA200706168 B ZA 200706168B
- Authority
- ZA
- South Africa
- Prior art keywords
- ibandronate polymorph
- ibandronate
- polymorph
- Prior art date
Links
- MPBVHIBUJCELCL-UHFFFAOYSA-N Ibandronate Chemical compound CCCCCN(C)CCC(O)(P(O)(O)=O)P(O)(O)=O MPBVHIBUJCELCL-UHFFFAOYSA-N 0.000 title 1
- 229940015872 ibandronate Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05100686 | 2005-02-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200706168B true ZA200706168B (en) | 2008-09-25 |
Family
ID=36090730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200706168A ZA200706168B (en) | 2005-02-01 | 2007-07-25 | Ibandronate polymorph A |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7714158B2 (xx) |
| EP (2) | EP2662380B1 (xx) |
| JP (2) | JP5828608B2 (xx) |
| KR (1) | KR100908529B1 (xx) |
| CN (1) | CN101111504B (xx) |
| AR (1) | AR053012A1 (xx) |
| AU (1) | AU2006210009B2 (xx) |
| BR (1) | BRPI0607092A2 (xx) |
| CA (1) | CA2594802C (xx) |
| CY (1) | CY1121703T1 (xx) |
| DK (1) | DK2662380T3 (xx) |
| ES (2) | ES2478302T3 (xx) |
| HU (1) | HUE042316T2 (xx) |
| IL (1) | IL184562A (xx) |
| LT (1) | LT2662380T (xx) |
| MX (1) | MX2007009107A (xx) |
| NO (1) | NO20073723L (xx) |
| PL (1) | PL2662380T3 (xx) |
| PT (1) | PT2662380T (xx) |
| RU (1) | RU2368617C2 (xx) |
| SI (1) | SI2662380T1 (xx) |
| TR (1) | TR201902609T4 (xx) |
| TW (1) | TWI374889B (xx) |
| WO (1) | WO2006081963A1 (xx) |
| ZA (1) | ZA200706168B (xx) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1713489E (pt) | 2004-08-23 | 2011-03-03 | Teva Pharma | Forma cristalina de ibandronato de sódio e processos para a sua preparação |
| SI1848727T1 (sl) * | 2005-02-01 | 2015-09-30 | F. Hoffmann-La Roche Ag | Polimorf b ibandronata |
| WO2007074475A2 (en) * | 2005-12-27 | 2007-07-05 | Natco Pharma Limited | Novel polymorphic forms of ibandronate |
| CA2656053A1 (en) * | 2006-07-03 | 2008-01-10 | Generics [Uk] Limited | Novel process for the preparation of bisphosphonic acids |
| EP2009016A3 (en) * | 2006-11-16 | 2009-02-25 | Teva Pharmaceutical Industries Ltd | Process for preparing crystalline form of ibandronate sodium |
| CA2570949A1 (en) * | 2006-12-12 | 2008-06-12 | Apotex Pharmachem Inc. | Ibandronate sodium propylene glycol solvate and processes for the preparation thereof |
| PL2144919T3 (pl) * | 2007-04-11 | 2016-05-31 | Hoffmann La Roche | Wieloetapowa synteza ibandronianu |
| KR20100014728A (ko) | 2007-04-19 | 2010-02-10 | 닥터 레디스 레보러터리즈 리미티드 | 이반드로네이트 나트륨 다형태 |
| WO2009020483A1 (en) * | 2007-08-09 | 2009-02-12 | Teva Pharmaceutical Industries Ltd. | Crystalline forms of ibandronate sodium |
| EP2128166A1 (en) | 2008-05-20 | 2009-12-02 | Chemo Ibérica, S.A. | Polymorphic forms of Ibandronate sodium and processes for preparation thereof |
| EP2180003A1 (en) | 2008-10-21 | 2010-04-28 | Zentiva, k.s. | Preparation of ibandronate trisodium |
| EP2609101B1 (en) | 2010-07-14 | 2015-01-28 | Pharmathen S.A. | Process for the preparation of 3-(n-methyl-n-pentyl)amino-1-hydroxypropane-1,1-diphosphonic acid salt or derivatives thereof |
| TR201200588A2 (tr) | 2012-01-18 | 2012-07-23 | Koçak Farma İlaç Ve Ki̇mya Sanayi̇ Anoni̇m Şi̇rketi̇ | Sodyum ibandronat monohidrat polimorflarini ve polimorflu karışımlarını hazırlamak için prosesler. |
| KR20200085441A (ko) | 2019-01-07 | 2020-07-15 | 엠에프씨 주식회사 | 이반드로네이트의 신규한 결정형 및 이의 제조방법 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3623397A1 (de) * | 1986-07-11 | 1988-01-14 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
| TW198039B (xx) * | 1988-11-28 | 1993-01-11 | Ciba Geigy Ag | |
| IT1303672B1 (it) * | 1998-07-28 | 2001-02-23 | Nicox Sa | Sali nitrati di farmaci attivi nei disordini ossei |
| EP0998932A1 (de) * | 1998-10-09 | 2000-05-10 | Boehringer Mannheim Gmbh | Feste pharmazeutische Darreichungsform enthaltend Diphosphonsäure oder deren Salze und Verfahren zu ihrer Herstellung |
| DE69907495T2 (de) | 1998-10-16 | 2004-05-06 | Akzo Nobel N.V. | (7alpha,17alpha)-17-hydroxy-7-methyl-19-nor-17-pregn-5-(10)-en-20-yn-3-on als reine verbindung |
| ATE303153T1 (de) * | 1998-12-04 | 2005-09-15 | Roche Diagnostics Gmbh | Ibandroinsäure zur förderung der osseointegration der endoprothesen |
| US6677320B2 (en) | 2000-01-20 | 2004-01-13 | Hoffmann-La Roches Inc. | Parenteral bisphosphonate composition with improved local tolerance |
| CN1404836A (zh) * | 2001-09-14 | 2003-03-26 | 中生北方生物工程开发研究所 | 埃本膦酸钠作为预防和治疗骨质疏松症的药物的有效成分的应用 |
| BR0308901A (pt) * | 2002-05-10 | 2005-01-04 | Hoffmann La Roche | ácidos bisfosfÈnicos para tratamento e prevenção de osteoporose |
| SI1596870T2 (sl) * | 2002-12-20 | 2011-07-29 | Hoffmann La Roche | Formulacija z visokim odmerkom ibandronata |
| WO2006002348A2 (en) | 2004-06-23 | 2006-01-05 | Teva Pharmaceutical Industies Ltd. | Solid and crystalline ibandronic acid |
| PT1713489E (pt) | 2004-08-23 | 2011-03-03 | Teva Pharma | Forma cristalina de ibandronato de sódio e processos para a sua preparação |
-
2006
- 2006-01-24 WO PCT/EP2006/000580 patent/WO2006081963A1/en active Application Filing
- 2006-01-24 CN CN2006800036914A patent/CN101111504B/zh not_active Expired - Fee Related
- 2006-01-24 JP JP2007553502A patent/JP5828608B2/ja active Active
- 2006-01-24 AU AU2006210009A patent/AU2006210009B2/en not_active Ceased
- 2006-01-24 BR BRPI0607092-2A patent/BRPI0607092A2/pt active Search and Examination
- 2006-01-24 ES ES06706375.0T patent/ES2478302T3/es active Active
- 2006-01-24 EP EP13161008.1A patent/EP2662380B1/en active Active
- 2006-01-24 PL PL13161008T patent/PL2662380T3/pl unknown
- 2006-01-24 EP EP06706375.0A patent/EP1848728B1/en not_active Revoked
- 2006-01-24 LT LTEP13161008.1T patent/LT2662380T/lt unknown
- 2006-01-24 MX MX2007009107A patent/MX2007009107A/es active IP Right Grant
- 2006-01-24 TR TR2019/02609T patent/TR201902609T4/tr unknown
- 2006-01-24 PT PT13161008T patent/PT2662380T/pt unknown
- 2006-01-24 US US11/338,468 patent/US7714158B2/en active Active
- 2006-01-24 HU HUE13161008A patent/HUE042316T2/hu unknown
- 2006-01-24 SI SI200632318T patent/SI2662380T1/sl unknown
- 2006-01-24 RU RU2007132701/04A patent/RU2368617C2/ru not_active IP Right Cessation
- 2006-01-24 KR KR1020077019795A patent/KR100908529B1/ko active IP Right Grant
- 2006-01-24 DK DK13161008.1T patent/DK2662380T3/en active
- 2006-01-24 CA CA2594802A patent/CA2594802C/en not_active Expired - Fee Related
- 2006-01-24 ES ES13161008T patent/ES2712644T3/es active Active
- 2006-01-27 TW TW095103582A patent/TWI374889B/zh not_active IP Right Cessation
- 2006-01-30 AR ARP060100335A patent/AR053012A1/es not_active Application Discontinuation
-
2007
- 2007-07-12 IL IL184562A patent/IL184562A/en not_active IP Right Cessation
- 2007-07-18 NO NO20073723A patent/NO20073723L/no not_active Application Discontinuation
- 2007-07-25 ZA ZA200706168A patent/ZA200706168B/xx unknown
-
2015
- 2015-06-30 JP JP2015131571A patent/JP6039754B2/ja active Active
-
2019
- 2019-02-21 CY CY20191100222T patent/CY1121703T1/el unknown
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