TR201902369T4 - Steroid laktam esterleri ve bis(2-kloroetil) aminofenoksi propanoik asit türevleri. - Google Patents

Steroid laktam esterleri ve bis(2-kloroetil) aminofenoksi propanoik asit türevleri. Download PDF

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Publication number
TR201902369T4
TR201902369T4 TR2019/02369T TR201902369T TR201902369T4 TR 201902369 T4 TR201902369 T4 TR 201902369T4 TR 2019/02369 T TR2019/02369 T TR 2019/02369T TR 201902369 T TR201902369 T TR 201902369T TR 201902369 T4 TR201902369 T4 TR 201902369T4
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TR
Turkey
Prior art keywords
chloroethyl
bis
propanoic acid
steroid
acid derivatives
Prior art date
Application number
TR2019/02369T
Other languages
English (en)
Inventor
Trafalis Dimitrios
Original Assignee
Energonbio Tech S A
Galenica S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Energonbio Tech S A, Galenica S A filed Critical Energonbio Tech S A
Publication of TR201902369T4 publication Critical patent/TR201902369T4/tr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Alkilleyici bis(2-kloroetil)aminofenoksi propanoik asit ve ikame edilen türevlerine sahip yeni homo-aza-steroid esterler, preparasyonlarına yönelik prosesler, bunları içeren farmasötik bileşimler ve kanser tedavisinde kullanımları.
TR2019/02369T 2015-06-29 2016-06-28 Steroid laktam esterleri ve bis(2-kloroetil) aminofenoksi propanoik asit türevleri. TR201902369T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15386022 2015-06-29

Publications (1)

Publication Number Publication Date
TR201902369T4 true TR201902369T4 (tr) 2019-03-21

Family

ID=53716416

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/02369T TR201902369T4 (tr) 2015-06-29 2016-06-28 Steroid laktam esterleri ve bis(2-kloroetil) aminofenoksi propanoik asit türevleri.

Country Status (24)

Country Link
US (1) US10208083B2 (tr)
EP (1) EP3186268B1 (tr)
JP (1) JP6708670B2 (tr)
KR (1) KR102647748B1 (tr)
CN (1) CN107835817B (tr)
AU (1) AU2016286205B8 (tr)
BR (1) BR112017027850B1 (tr)
CA (1) CA2990307C (tr)
CY (1) CY1121264T1 (tr)
DK (1) DK3186268T3 (tr)
ES (1) ES2712429T3 (tr)
HK (1) HK1248241A1 (tr)
HR (1) HRP20190327T1 (tr)
HU (1) HUE043468T2 (tr)
IL (1) IL256456B (tr)
LT (1) LT3186268T (tr)
MX (1) MX369930B (tr)
PL (1) PL3186268T3 (tr)
PT (1) PT3186268T (tr)
RS (1) RS58630B1 (tr)
RU (1) RU2719457C2 (tr)
SI (1) SI3186268T1 (tr)
TR (1) TR201902369T4 (tr)
WO (1) WO2017001439A1 (tr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1527161A (en) * 1976-02-19 1978-10-04 Leo A Enol esters of steroids
SU1361152A1 (ru) * 1983-07-08 1987-12-23 Всесоюзный онкологический научный центр АМН СССР Сложные моноэфиры 5 @ -андростандиола-3 @ ,17 @ ,про вл ющие противоопухолевую и гормональную активность
US10081592B2 (en) * 2012-03-23 2018-09-25 The Board Of Trustees Of The University Of Illinois Complex and structurally diverse compounds

Also Published As

Publication number Publication date
EP3186268A1 (en) 2017-07-05
JP2018519311A (ja) 2018-07-19
CN107835817A (zh) 2018-03-23
DK3186268T3 (en) 2019-03-18
CA2990307A1 (en) 2017-01-05
IL256456A (en) 2018-02-28
PT3186268T (pt) 2019-02-27
RS58630B1 (sr) 2019-05-31
EP3186268B1 (en) 2018-11-28
KR102647748B1 (ko) 2024-03-14
CY1121264T1 (el) 2020-05-29
RU2018103071A3 (tr) 2019-09-30
ES2712429T3 (es) 2019-05-13
RU2719457C2 (ru) 2020-04-17
IL256456B (en) 2019-11-28
CA2990307C (en) 2023-09-26
MX2017016679A (es) 2018-07-06
CN107835817B (zh) 2020-04-21
RU2018103071A (ru) 2019-07-30
AU2016286205A1 (en) 2017-12-14
HRP20190327T1 (hr) 2019-05-03
HK1248241A1 (zh) 2018-10-12
KR20180015266A (ko) 2018-02-12
BR112017027850A2 (pt) 2018-09-04
PL3186268T3 (pl) 2019-05-31
BR112017027850B1 (pt) 2024-01-02
SI3186268T1 (sl) 2019-05-31
AU2016286205B2 (en) 2019-11-28
US20180194800A1 (en) 2018-07-12
LT3186268T (lt) 2019-04-25
US10208083B2 (en) 2019-02-19
WO2017001439A1 (en) 2017-01-05
MX369930B (es) 2019-11-26
HUE043468T2 (hu) 2019-08-28
AU2016286205B8 (en) 2020-04-16
JP6708670B2 (ja) 2020-06-10

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