CY1121264T1 - Εστερες στεροειδικης λακταμης και παραγωγα αμφι(2-χλωροαιθυλ)-αμινοφαινοξυ-προπανοϊκου οξεος - Google Patents

Εστερες στεροειδικης λακταμης και παραγωγα αμφι(2-χλωροαιθυλ)-αμινοφαινοξυ-προπανοϊκου οξεος

Info

Publication number
CY1121264T1
CY1121264T1 CY20191100191T CY191100191T CY1121264T1 CY 1121264 T1 CY1121264 T1 CY 1121264T1 CY 20191100191 T CY20191100191 T CY 20191100191T CY 191100191 T CY191100191 T CY 191100191T CY 1121264 T1 CY1121264 T1 CY 1121264T1
Authority
CY
Cyprus
Prior art keywords
amphi
aminophenoxy
chloroethyl
propanoic acid
derivatives
Prior art date
Application number
CY20191100191T
Other languages
English (en)
Inventor
Dimitrios TRAFALIS
Original Assignee
Galenica S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galenica S.A. filed Critical Galenica S.A.
Publication of CY1121264T1 publication Critical patent/CY1121264T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Καινοφανείς ομο-αζα-στεροειδικοί εστέρες με αλκυλιωτικό αμφι(2-χλωροαιθυλ)αμινοφαινοξυ-προπανοϊκό οξύ και υποκατεστημένα παράγωγα, διεργασίες για την παρασκευή αυτών, φαρμακευτικές συνθέσεις περιέχοντας αυτούς και η χρήση αυτών στην αγωγή του καρκίνου.
CY20191100191T 2015-06-29 2019-02-13 Εστερες στεροειδικης λακταμης και παραγωγα αμφι(2-χλωροαιθυλ)-αμινοφαινοξυ-προπανοϊκου οξεος CY1121264T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15386022 2015-06-29
PCT/EP2016/065071 WO2017001439A1 (en) 2015-06-29 2016-06-28 Esters of steroidal lactam and bis(2-chloroethyl) aminophenoxy propanoic acid derivatives

Publications (1)

Publication Number Publication Date
CY1121264T1 true CY1121264T1 (el) 2020-05-29

Family

ID=53716416

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20191100191T CY1121264T1 (el) 2015-06-29 2019-02-13 Εστερες στεροειδικης λακταμης και παραγωγα αμφι(2-χλωροαιθυλ)-αμινοφαινοξυ-προπανοϊκου οξεος

Country Status (24)

Country Link
US (1) US10208083B2 (el)
EP (1) EP3186268B1 (el)
JP (1) JP6708670B2 (el)
KR (1) KR102647748B1 (el)
CN (1) CN107835817B (el)
AU (1) AU2016286205B8 (el)
BR (1) BR112017027850B1 (el)
CA (1) CA2990307C (el)
CY (1) CY1121264T1 (el)
DK (1) DK3186268T3 (el)
ES (1) ES2712429T3 (el)
HK (1) HK1248241A1 (el)
HR (1) HRP20190327T1 (el)
HU (1) HUE043468T2 (el)
IL (1) IL256456B (el)
LT (1) LT3186268T (el)
MX (1) MX369930B (el)
PL (1) PL3186268T3 (el)
PT (1) PT3186268T (el)
RS (1) RS58630B1 (el)
RU (1) RU2719457C2 (el)
SI (1) SI3186268T1 (el)
TR (1) TR201902369T4 (el)
WO (1) WO2017001439A1 (el)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1527161A (en) * 1976-02-19 1978-10-04 Leo A Enol esters of steroids
SU1361152A1 (ru) * 1983-07-08 1987-12-23 Всесоюзный онкологический научный центр АМН СССР Сложные моноэфиры 5 @ -андростандиола-3 @ ,17 @ ,про вл ющие противоопухолевую и гормональную активность
US10081592B2 (en) * 2012-03-23 2018-09-25 The Board Of Trustees Of The University Of Illinois Complex and structurally diverse compounds

Also Published As

Publication number Publication date
AU2016286205B2 (en) 2019-11-28
RU2018103071A3 (el) 2019-09-30
CN107835817A (zh) 2018-03-23
BR112017027850B1 (pt) 2024-01-02
TR201902369T4 (tr) 2019-03-21
IL256456A (en) 2018-02-28
IL256456B (en) 2019-11-28
KR20180015266A (ko) 2018-02-12
CA2990307A1 (en) 2017-01-05
CN107835817B (zh) 2020-04-21
ES2712429T3 (es) 2019-05-13
AU2016286205A1 (en) 2017-12-14
US20180194800A1 (en) 2018-07-12
CA2990307C (en) 2023-09-26
KR102647748B1 (ko) 2024-03-14
PT3186268T (pt) 2019-02-27
AU2016286205B8 (en) 2020-04-16
WO2017001439A1 (en) 2017-01-05
MX369930B (es) 2019-11-26
HRP20190327T1 (hr) 2019-05-03
SI3186268T1 (sl) 2019-05-31
RS58630B1 (sr) 2019-05-31
DK3186268T3 (en) 2019-03-18
JP6708670B2 (ja) 2020-06-10
HK1248241A1 (zh) 2018-10-12
RU2018103071A (ru) 2019-07-30
RU2719457C2 (ru) 2020-04-17
MX2017016679A (es) 2018-07-06
EP3186268B1 (en) 2018-11-28
US10208083B2 (en) 2019-02-19
EP3186268A1 (en) 2017-07-05
JP2018519311A (ja) 2018-07-19
LT3186268T (lt) 2019-04-25
BR112017027850A2 (pt) 2018-09-04
HUE043468T2 (hu) 2019-08-28
PL3186268T3 (pl) 2019-05-31

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