TR201806885T4 - Çölyak sprue hastalığının tedavisi için bileşimler ve yöntemler. - Google Patents
Çölyak sprue hastalığının tedavisi için bileşimler ve yöntemler. Download PDFInfo
- Publication number
- TR201806885T4 TR201806885T4 TR2018/06885T TR201806885T TR201806885T4 TR 201806885 T4 TR201806885 T4 TR 201806885T4 TR 2018/06885 T TR2018/06885 T TR 2018/06885T TR 201806885 T TR201806885 T TR 201806885T TR 201806885 T4 TR201806885 T4 TR 201806885T4
- Authority
- TR
- Turkey
- Prior art keywords
- seq
- amino acid
- polypeptides
- acid sequence
- activity
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161521899P | 2011-08-10 | 2011-08-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201806885T4 true TR201806885T4 (tr) | 2018-06-21 |
Family
ID=46690751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2018/06885T TR201806885T4 (tr) | 2011-08-10 | 2012-08-10 | Çölyak sprue hastalığının tedavisi için bileşimler ve yöntemler. |
Country Status (18)
| Country | Link |
|---|---|
| US (7) | US9289473B2 (enExample) |
| EP (3) | EP4023243A3 (enExample) |
| JP (5) | JP6342802B2 (enExample) |
| CA (1) | CA2882502A1 (enExample) |
| CY (1) | CY1120877T1 (enExample) |
| DK (1) | DK2718434T3 (enExample) |
| ES (2) | ES2896489T3 (enExample) |
| HR (1) | HRP20180687T1 (enExample) |
| HU (1) | HUE037870T2 (enExample) |
| LT (1) | LT2718434T (enExample) |
| NO (1) | NO2718434T3 (enExample) |
| PL (2) | PL3400958T3 (enExample) |
| PT (1) | PT2718434T (enExample) |
| RS (1) | RS57234B1 (enExample) |
| SI (1) | SI2718434T1 (enExample) |
| SM (1) | SMT201800249T1 (enExample) |
| TR (1) | TR201806885T4 (enExample) |
| WO (1) | WO2013023151A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT2718434T (lt) | 2011-08-10 | 2018-08-10 | University Of Washington Through Its Center For Commercialization | Kompozicijos ir būdai, skirti celiakijos gydymui |
| US10266815B2 (en) * | 2013-08-14 | 2019-04-23 | University Of Washington Through Its Center For Commercialization | Compositions and methods for treating celiac sprue disease |
| EP3081942A1 (en) * | 2015-04-17 | 2016-10-19 | Roche Diagniostics GmbH | Pressure transmission liquid for cellular analyzer, cellular analyzer and method for analyzing a liquid cellular sample |
| TN2017000520A1 (en) * | 2015-06-08 | 2019-04-12 | Univ California | Compositions and methods for treating celiac sprue disease |
| US12655410B2 (en) | 2016-12-22 | 2026-06-16 | Ew Nutrition Gmbh | Stable protease variants |
| MX2019007287A (es) * | 2016-12-22 | 2019-09-27 | Ew Nutrition Gmbh | Variantes de proteasas estables. |
| WO2020087017A1 (en) * | 2018-10-26 | 2020-04-30 | The Regents Of The University Of California | Use of proteolytic enzymes to enhance protein bioavailability |
| US20240226248A9 (en) * | 2018-10-26 | 2024-07-11 | The Regents Of The University Of California | Methods and compositions for improving protein hydrolysis |
| US20250064903A1 (en) | 2020-10-30 | 2025-02-27 | University Of Washington | Compositions and methods for treating celiac sprue disease |
| JP7900846B2 (ja) | 2022-01-26 | 2026-08-05 | ダイジェスティーバ・インコーポレイテッド | 血糖安定化方法及び組成物 |
| WO2025068987A1 (en) | 2023-09-28 | 2025-04-03 | Takeda Pharmaceutical Company Limited | A method of producing a kumamolisin-as polypeptide |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2688229B1 (fr) | 1992-03-09 | 1995-06-23 | Ulice Soc | Procede de synthese enzymatique d'esters alkyliques de peptides, produits ainsi obtenus et utilisation desdits produits. |
| JP2002078489A (ja) * | 2000-09-04 | 2002-03-19 | Daiwa Kasei Kk | セリン残基が活性発現に関与する新規酸性プロテアーゼ |
| AU2003215272B2 (en) | 2002-02-14 | 2008-04-03 | The Board Of Trustees Of The Leland Stanford Junior University | Enzyme treatment of foodstuffs for celiac sprue |
| US7320788B2 (en) | 2002-02-14 | 2008-01-22 | The Board Of Trustees Of The Leland Stanford Junior University | Enzyme treatment of foodstuffs for Celiac Sprue |
| US8143210B2 (en) | 2002-02-14 | 2012-03-27 | The Board Of Trustees Of The Leland Stanford Junior University | Enzyme treatment of foodstuffs for celiac sprue |
| US7265093B2 (en) | 2002-05-14 | 2007-09-04 | The Board Of Trustees Of The Leland Stanford Junior University | Drug therapy for Celiac Sprue |
| US7462688B2 (en) | 2002-05-14 | 2008-12-09 | The Board Of Trustees Of The Leland Stanford Junior University | Peptides for diagnostic and therapeutic methods for celiac sprue |
| US7202216B2 (en) | 2002-05-14 | 2007-04-10 | The Board Of Trustees Of The Leland Stanford Junior University | Drug therapy for celiac sprue |
| US7605150B2 (en) | 2002-05-14 | 2009-10-20 | The Board Of Trustees Of The Leland Stanford Junior University | Drug therapy for Celiac Sprue |
| ATE554392T1 (de) | 2002-11-20 | 2012-05-15 | Univ Leland Stanford Junior | Diagnoseverfahren für sprue/zöliakie |
| US7579313B2 (en) | 2003-11-18 | 2009-08-25 | The Board Of Trustees Of The Leland Stanford Junior University | Transglutaminase inhibitors and methods of use thereof |
| US7563864B2 (en) | 2004-04-26 | 2009-07-21 | Celiac Sprue Research Foundation | Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten |
| US7534426B2 (en) | 2004-04-26 | 2009-05-19 | The Board Of Trustees Of The Leland Stanford Junior University | Glutenase enzyme assays |
| US7628985B2 (en) | 2004-04-26 | 2009-12-08 | The Board Of Regents Of The Leland Stanford Junior University | Therapeutic enzyme formulations and uses thereof in celiac sprue and/or dermatitis herpetoformis |
| EP1600141B1 (en) | 2004-05-24 | 2013-04-17 | 3M Deutschland GmbH | Collagenolytic active enzyme containing compositions for the treatment of dental caries |
| EP1726643A1 (en) * | 2005-05-27 | 2006-11-29 | Direvo Biotech AG | Method for the provision, identification and selection of proteases with altered sensitivity to activity-modulating substances |
| NZ591025A (en) | 2008-08-21 | 2013-01-25 | Alvine Pharmaceuticals Inc | Formulation for oral administration of proteins |
| LT2718434T (lt) | 2011-08-10 | 2018-08-10 | University Of Washington Through Its Center For Commercialization | Kompozicijos ir būdai, skirti celiakijos gydymui |
| JP6203743B2 (ja) | 2011-12-06 | 2017-09-27 | フオンダツイオーネ・イステイトウート・インスブリコ・デイ・リチエルカ・ペル・ラ・ビータ | アクチノミセス・アクチノアロムルス（ＡＣＴＩＮＯＭＹＣＥＴＥＡＣＴＩＮＯＡＬＬＯＭＵＲＵＳ）由来の、酸性ｐＨにてグルテンペプチドおよびタンパク質を加水分解できる新規プロテアーゼ |
| US10266815B2 (en) | 2013-08-14 | 2019-04-23 | University Of Washington Through Its Center For Commercialization | Compositions and methods for treating celiac sprue disease |
| TN2017000520A1 (en) | 2015-06-08 | 2019-04-12 | Univ California | Compositions and methods for treating celiac sprue disease |
-
2012
- 2012-08-10 LT LTEP12748354.3T patent/LT2718434T/lt unknown
- 2012-08-10 SI SI201231269T patent/SI2718434T1/en unknown
- 2012-08-10 EP EP21187810.3A patent/EP4023243A3/en not_active Withdrawn
- 2012-08-10 HU HUE12748354A patent/HUE037870T2/hu unknown
- 2012-08-10 DK DK12748354.3T patent/DK2718434T3/en active
- 2012-08-10 EP EP12748354.3A patent/EP2718434B1/en active Active
- 2012-08-10 CA CA2882502A patent/CA2882502A1/en active Pending
- 2012-08-10 PT PT127483543T patent/PT2718434T/pt unknown
- 2012-08-10 HR HRP20180687TT patent/HRP20180687T1/hr unknown
- 2012-08-10 WO PCT/US2012/050364 patent/WO2013023151A2/en not_active Ceased
- 2012-08-10 TR TR2018/06885T patent/TR201806885T4/tr unknown
- 2012-08-10 NO NO12748354A patent/NO2718434T3/no unknown
- 2012-08-10 PL PL18162586T patent/PL3400958T3/pl unknown
- 2012-08-10 PL PL12748354T patent/PL2718434T3/pl unknown
- 2012-08-10 RS RS20180609A patent/RS57234B1/sr unknown
- 2012-08-10 ES ES18162586T patent/ES2896489T3/es active Active
- 2012-08-10 ES ES12748354.3T patent/ES2667418T3/es active Active
- 2012-08-10 US US14/131,601 patent/US9289473B2/en active Active
- 2012-08-10 EP EP18162586.4A patent/EP3400958B1/en active Active
- 2012-08-10 SM SM20180249T patent/SMT201800249T1/it unknown
- 2012-08-10 JP JP2014525175A patent/JP6342802B2/ja active Active
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2016
- 2016-01-26 US US15/006,341 patent/US9707280B2/en active Active
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2017
- 2017-06-26 US US15/633,065 patent/US9925249B2/en active Active
- 2017-07-07 JP JP2017133615A patent/JP6502428B2/ja active Active
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2018
- 2018-02-14 US US15/896,536 patent/US10149892B2/en active Active
- 2018-06-21 CY CY181100648T patent/CY1120877T1/el unknown
- 2018-11-28 US US16/203,109 patent/US10874720B2/en active Active
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2019
- 2019-03-20 JP JP2019052599A patent/JP2019162107A/ja active Pending
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2020
- 2020-12-07 US US17/114,294 patent/US20210085761A1/en not_active Abandoned
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2021
- 2021-03-23 JP JP2021048356A patent/JP2021094031A/ja active Pending
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2023
- 2023-11-20 US US18/513,879 patent/US12544430B2/en active Active
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2024
- 2024-01-11 JP JP2024002401A patent/JP2024028452A/ja active Pending
Also Published As
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