ES2896489T3 - Composiciones y procedimientos para el tratamiento de la enfermedad esprúe celíaco - Google Patents
Composiciones y procedimientos para el tratamiento de la enfermedad esprúe celíaco Download PDFInfo
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- ES2896489T3 ES2896489T3 ES18162586T ES18162586T ES2896489T3 ES 2896489 T3 ES2896489 T3 ES 2896489T3 ES 18162586 T ES18162586 T ES 18162586T ES 18162586 T ES18162586 T ES 18162586T ES 2896489 T3 ES2896489 T3 ES 2896489T3
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
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- Chemical & Material Sciences (AREA)
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- Veterinary Medicine (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Wood Science & Technology (AREA)
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- Zoology (AREA)
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- Pulmonology (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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- Peptides Or Proteins (AREA)
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| PL3400958T3 (pl) | 2011-08-10 | 2022-01-03 | University Of Washington Through Its Center For Commercialization | Kompozycje i metody leczenia celiakii |
| EP3033100B1 (en) * | 2013-08-14 | 2018-10-03 | University Of Washington Through Its Center For Commercialization | Compositions for treating celiac sprue disease |
| EP3081942A1 (en) * | 2015-04-17 | 2016-10-19 | Roche Diagniostics GmbH | Pressure transmission liquid for cellular analyzer, cellular analyzer and method for analyzing a liquid cellular sample |
| EA037603B1 (ru) | 2015-06-08 | 2021-04-20 | Юниверсити Оф Вашингтон | Композиции и способы для лечения целиакии спру |
| BR112019012980A2 (pt) * | 2016-12-22 | 2020-05-26 | Ew Nutrition Gmbh | Variantes estáveis de protease |
| US20240226248A9 (en) * | 2018-10-26 | 2024-07-11 | The Regents Of The University Of California | Methods and compositions for improving protein hydrolysis |
| WO2020087017A1 (en) * | 2018-10-26 | 2020-04-30 | The Regents Of The University Of California | Use of proteolytic enzymes to enhance protein bioavailability |
| EP4237554A1 (en) | 2020-10-30 | 2023-09-06 | University of Washington | Compositions and methods for treating celiac sprue disease |
| JP2025504049A (ja) | 2022-01-26 | 2025-02-06 | ダイジェスティーバ・インコーポレイテッド | 血糖安定化方法及び組成物 |
| WO2025068987A1 (en) | 2023-09-28 | 2025-04-03 | Takeda Pharmaceutical Company Limited | A method of producing a kumamolisin-as polypeptide |
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| JP2002078489A (ja) * | 2000-09-04 | 2002-03-19 | Daiwa Kasei Kk | セリン残基が活性発現に関与する新規酸性プロテアーゼ |
| US7320788B2 (en) | 2002-02-14 | 2008-01-22 | The Board Of Trustees Of The Leland Stanford Junior University | Enzyme treatment of foodstuffs for Celiac Sprue |
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| US8143210B2 (en) | 2002-02-14 | 2012-03-27 | The Board Of Trustees Of The Leland Stanford Junior University | Enzyme treatment of foodstuffs for celiac sprue |
| WO2003096984A2 (en) | 2002-05-14 | 2003-11-27 | The Board Of Trustees Of The Leland Stanford Junior University | Drug therapy for celiac sprue |
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| US7265093B2 (en) | 2002-05-14 | 2007-09-04 | The Board Of Trustees Of The Leland Stanford Junior University | Drug therapy for Celiac Sprue |
| US7202216B2 (en) | 2002-05-14 | 2007-04-10 | The Board Of Trustees Of The Leland Stanford Junior University | Drug therapy for celiac sprue |
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| US7579313B2 (en) | 2003-11-18 | 2009-08-25 | The Board Of Trustees Of The Leland Stanford Junior University | Transglutaminase inhibitors and methods of use thereof |
| US7563864B2 (en) | 2004-04-26 | 2009-07-21 | Celiac Sprue Research Foundation | Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten |
| US7628985B2 (en) | 2004-04-26 | 2009-12-08 | The Board Of Regents Of The Leland Stanford Junior University | Therapeutic enzyme formulations and uses thereof in celiac sprue and/or dermatitis herpetoformis |
| US7534426B2 (en) | 2004-04-26 | 2009-05-19 | The Board Of Trustees Of The Leland Stanford Junior University | Glutenase enzyme assays |
| EP1600141B1 (en) | 2004-05-24 | 2013-04-17 | 3M Deutschland GmbH | Collagenolytic active enzyme containing compositions for the treatment of dental caries |
| EP1726643A1 (en) * | 2005-05-27 | 2006-11-29 | Direvo Biotech AG | Method for the provision, identification and selection of proteases with altered sensitivity to activity-modulating substances |
| AU2009283157B2 (en) | 2008-08-21 | 2015-02-26 | Alvine Pharmaceuticals, Inc. | Formulation for oral administration of proteins |
| PL3400958T3 (pl) | 2011-08-10 | 2022-01-03 | University Of Washington Through Its Center For Commercialization | Kompozycje i metody leczenia celiakii |
| WO2013083338A1 (en) | 2011-12-06 | 2013-06-13 | Fondazione Istituto Insubrico Di Ricerca Per La Vita | New proteases able to hydrolyze gluten peptides and proteins at acidic ph, from the actinomycete actinoallomurus |
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2016
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2017
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2018
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2019
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2020
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2024
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