TR200400049T2 - Eimeria maxima gametositinden rekombinant 56 ve 82 kda antijenleri kodlayan nükleik asitler - Google Patents

Eimeria maxima gametositinden rekombinant 56 ve 82 kda antijenleri kodlayan nükleik asitler

Info

Publication number
TR200400049T2
TR200400049T2 TR2004/00049T TR200400049T TR200400049T2 TR 200400049 T2 TR200400049 T2 TR 200400049T2 TR 2004/00049 T TR2004/00049 T TR 2004/00049T TR 200400049 T TR200400049 T TR 200400049T TR 200400049 T2 TR200400049 T2 TR 200400049T2
Authority
TR
Turkey
Prior art keywords
kda
recombinant
eimeria maxima
provides
present
Prior art date
Application number
TR2004/00049T
Other languages
English (en)
Inventor
Sabina Belli I.
Nicolas Smith C.
Wallach Michael
Original Assignee
Biological Laboratories Teva Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biological Laboratories Teva Ltd. filed Critical Biological Laboratories Teva Ltd.
Publication of TR200400049T2 publication Critical patent/TR200400049T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/455—Eimeria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Mevcut buluş , meleküller ağırlıkları 56 ve 82 kDA olan ana Eimeria maxima gametosit antijenlerinden ikisinin rekombinant klonlanmasını ve sıralanmasını ve bu rekombinant antijenlerin plazmit pTrcHis kullanılarak bir E.coli tanım sistemi içerisinde tanımlanmasını sağlar. Söz konusu buluş, kokidioz'a karşı rekombinant 56 kDa veya 82 kDa'lık antijen ihtiva eden bir aşı da sağlar. Söz konusu buluş, N-terminal ucunda burada tarif edilen amino asit sekansına sahip Eimeria maxima gametositlerine ait iki 30 kDa'lık protein ve üç 14 kDa'lık protein de sağlar. Söz konusu buluş, kokidioz'a karşı rekombinant 56 kDa veya 82 kDa'lık antijen ve yukarıda adı geçen proteinlerden herhangi birini içeren bir aşı da sağlar
TR2004/00049T 2001-07-06 2002-07-03 Eimeria maxima gametositinden rekombinant 56 ve 82 kda antijenleri kodlayan nükleik asitler TR200400049T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30369901P 2001-07-06 2001-07-06

Publications (1)

Publication Number Publication Date
TR200400049T2 true TR200400049T2 (tr) 2009-01-21

Family

ID=23173289

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2004/00049T TR200400049T2 (tr) 2001-07-06 2002-07-03 Eimeria maxima gametositinden rekombinant 56 ve 82 kda antijenleri kodlayan nükleik asitler

Country Status (18)

Country Link
US (2) US7423137B2 (tr)
EP (1) EP1432722B1 (tr)
JP (2) JP2005501533A (tr)
CN (1) CN1606565B (tr)
AT (1) ATE454392T1 (tr)
AU (1) AU2002316558B2 (tr)
BR (1) BR0210853A (tr)
CA (1) CA2467006A1 (tr)
DE (1) DE60235021D1 (tr)
ES (1) ES2339227T3 (tr)
HU (1) HUP0600028A3 (tr)
IL (2) IL159716A0 (tr)
MX (1) MXPA04000127A (tr)
PL (1) PL366540A1 (tr)
RU (1) RU2004103469A (tr)
TR (1) TR200400049T2 (tr)
WO (1) WO2003004683A2 (tr)
ZA (1) ZA200400479B (tr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ286915A (en) * 1995-07-03 1998-03-25 Akzo Nobel Nv Protein with one or more antigenic determinants of eimeria lactate dehydrogenase, its production and use
ZA200400479B (en) * 2001-07-06 2006-05-31 Abic Biolog Lab Teva Nucleic acids encoding recombinant 56 a 82 KDA antigens from gametocytes of Eimeria maxima and their use
RU2004103468A (ru) 2001-07-06 2005-04-20 Абик Байолоджикал Лэборетериз Тева Лтд. (Il) Нуклеиновые кислоты, кодирующие рекомбинантный 250 к-да-антиген спорозоитов/мерозоитов eimeria maxima, и их применения
PL2066339T3 (pl) 2006-09-18 2015-02-27 Univ Arkansas Kompozycje i sposoby zwiększania odpowiedzi immunologicznych
CA3156538C (en) 2007-11-01 2023-12-12 The Board Of Trustees Of The University Of Arkansas Compositions and methods of enhancing immune responses to eimeria
US20100150958A1 (en) * 2008-12-15 2010-06-17 Vectogen Pty Ltd. Methods and Compositions for Use of a Coccidiosis Vaccine
ES2968398T3 (es) 2013-02-14 2024-05-09 Univ Arkansas Composiciones y métodos para potenciar las respuestas inmunitarias a Eimeria o limitar la infección por Eimeria
CN106659787A (zh) * 2014-05-23 2017-05-10 辉宝动物保健公司 组合、组合物及向动物施用所述组合或组合物的方法
CN111471107B (zh) * 2020-04-27 2023-04-18 中国农业大学 抗鸡球虫多价重组蛋白卵黄抗体及其制备方法和应用
CN111840529B (zh) * 2020-07-30 2023-08-25 广东省农业科学院动物卫生研究所 一种柔嫩艾美耳球虫重组多肽疫苗vkvq的制备及其在抗鸡球虫病中的应用方法
CN113521264A (zh) * 2021-07-14 2021-10-22 中国农业科学院北京畜牧兽医研究所 一种鸽球虫病活疫苗及其制备方法和应用
CN114051971B (zh) * 2021-08-26 2023-08-29 山东农巧农业科技有限公司 一种高效率乳鸽生态养殖方法
CN114736308B (zh) * 2022-03-15 2022-12-27 四川宜美康科技有限公司 球虫抗原肽/il5的融合蛋白基因工程菌的制备及用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135712A3 (en) 1983-08-19 1987-05-27 American Cyanamid Company Antigens and monoclonal antibodies reactive against sporozoites of eimeria spp.
CA1340520C (en) 1984-06-05 1999-05-04 Karel Z. Newman Jr. Antigenic proteins and vaccines containing them and protective antibodies directed to them for prevention of coccidiosis caused by eimeria tenella and eimeria necatrix
US4639372A (en) 1984-06-29 1987-01-27 Merck & Co., Inc. Coccidiosis vaccine
US5496550A (en) 1986-08-14 1996-03-05 Chilwalner Method of reducing the output of Eimeria oocysts from a newborn chick
IL83523A (en) * 1986-08-14 1994-10-21 Chilwalner Partnership Method of purification of eimeria gametocytes and coccidiosis vaccine containing them
ZA893740B (en) * 1988-06-03 1990-02-28 Hoffmann La Roche Recombinant coccidiosis vaccines
ATE144146T1 (de) 1988-07-05 1996-11-15 British Tech Group Usa Gentechnologisch hergestellter coccidiose- impfstoff
ZA200400479B (en) 2001-07-06 2006-05-31 Abic Biolog Lab Teva Nucleic acids encoding recombinant 56 a 82 KDA antigens from gametocytes of Eimeria maxima and their use

Also Published As

Publication number Publication date
PL366540A1 (en) 2005-02-07
HUP0600028A3 (en) 2010-01-28
US7968695B2 (en) 2011-06-28
EP1432722A2 (en) 2004-06-30
IL159716A (en) 2010-06-16
ATE454392T1 (de) 2010-01-15
BR0210853A (pt) 2005-08-30
WO2003004683A3 (en) 2004-04-29
EP1432722B1 (en) 2010-01-06
MXPA04000127A (es) 2005-07-01
HUP0600028A2 (en) 2006-04-28
CA2467006A1 (en) 2003-01-16
RU2004103469A (ru) 2005-04-10
WO2003004683A2 (en) 2003-01-16
ES2339227T3 (es) 2010-05-18
US20050033042A1 (en) 2005-02-10
CN1606565B (zh) 2011-06-29
EP1432722A4 (en) 2005-08-10
CN1606565A (zh) 2005-04-13
US7423137B2 (en) 2008-09-09
JP2009077713A (ja) 2009-04-16
ZA200400479B (en) 2006-05-31
IL159716A0 (en) 2004-06-20
DE60235021D1 (de) 2010-02-25
US20090196888A1 (en) 2009-08-06
AU2002316558B2 (en) 2009-01-08
JP2005501533A (ja) 2005-01-20

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