TR200101757T2 - Vitronektin reseptör antagonisti farmasötikler - Google Patents
Vitronektin reseptör antagonisti farmasötiklerInfo
- Publication number
- TR200101757T2 TR200101757T2 TR2001/01757T TR200101757T TR200101757T2 TR 200101757 T2 TR200101757 T2 TR 200101757T2 TR 2001/01757 T TR2001/01757 T TR 2001/01757T TR 200101757 T TR200101757 T TR 200101757T TR 200101757 T2 TR200101757 T2 TR 200101757T2
- Authority
- TR
- Turkey
- Prior art keywords
- useful
- present
- new compounds
- treatment
- receptor antagonist
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/003—Peptides being substituted by heterocyclic radicals, e.g. bleomycin, phleomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
Abstract
Mevcut bulus, kanserin teshisi ve tedavisi için kullanisli olan (Q)d-Ln- Ch formülünün yeni bilesiklerini, bir hastada tümörlerin görüntülenmesi için yöntemleri ve bir hastada kanserin tadavi edilmesi için yöntemleri tarif etmektedir. Mevcut bulus, ayni zamanda terapötik anjiyojenez tedavisinin ve yeni anjiyojenik damar sisteminin ortadan kaldirilmasinin izlenmesi için faydali olan yeni bilesikler termin eder. Mevcut bulus ayrica ateroskleroz, restenoz, kardiyak iskemi ve miyokardin reperfüzyon harabiyetinin görüntülenmesi için faydali olan yeni bilesikleri temin eder. Mevcut bulus hala romatoid artritin tedavisi için kullanisli olan yeni bilesikleri de temin eder.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11283198P | 1998-12-18 | 1998-12-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200101757T2 true TR200101757T2 (tr) | 2001-12-21 |
Family
ID=22346057
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2001/01757T TR200101757T2 (tr) | 1998-12-18 | 1999-12-17 | Vitronektin reseptör antagonisti farmasötikler |
Country Status (6)
Country | Link |
---|---|
US (2) | US6558649B1 (tr) |
EP (1) | EP1140864A2 (tr) |
AU (1) | AU2371400A (tr) |
CA (1) | CA2349333A1 (tr) |
TR (1) | TR200101757T2 (tr) |
WO (1) | WO2000035887A2 (tr) |
Families Citing this family (18)
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US6569402B1 (en) | 1998-12-18 | 2003-05-27 | Bristol-Myers Squibb Pharma Company | Vitronectin receptor antagonist pharmaceuticals |
US6171578B1 (en) * | 1999-04-14 | 2001-01-09 | Diatide, Inc. | Benzodiazepine derivatives for imaging thrombi |
AU2001271435A1 (en) * | 2000-06-21 | 2002-01-02 | Bristol-Myers Squibb Pharma Company | Vitronectin receptor antagonist pharmaceuticals |
WO2003011226A2 (en) * | 2001-08-01 | 2003-02-13 | Smithkline Beecham Corporation | Products and drug delivery vehicles |
KR20100054884A (ko) | 2001-10-22 | 2010-05-25 | 더 스크립스 리서치 인스티튜트 | 항체 표적화 화합물 |
US7279150B2 (en) | 2002-01-24 | 2007-10-09 | Barnes-Jewish Hospital | Chelating agents with lipophilic carriers |
CN101249269A (zh) | 2002-01-24 | 2008-08-27 | 巴内斯-朱威胥医院 | 整联蛋白靶向的影像剂 |
US20040224986A1 (en) | 2002-08-16 | 2004-11-11 | Bart De Corte | Piperidinyl targeting compounds that selectively bind integrins |
EP1622647B1 (en) * | 2003-05-12 | 2009-11-25 | Lantheus Medical Imaging, Inc. | Vitronectin receptor antagonist compounds and their use in the preparation of radiopharmaceuticals |
WO2005032599A1 (en) * | 2003-09-30 | 2005-04-14 | Semafore Pharmaceuticals Inc. | Chelate based scaffolds in tumor targeting |
EP1768558A4 (en) | 2004-06-09 | 2009-11-25 | Kereos Inc | LIPOPHILES DERIVATIVES OF CHELATE MONOAMIDES |
US8758723B2 (en) * | 2006-04-19 | 2014-06-24 | The Board Of Regents Of The University Of Texas System | Compositions and methods for cellular imaging and therapy |
CN101516899B (zh) * | 2006-04-19 | 2016-07-06 | 得克萨斯大学体系董事会 | 细胞成像和治疗的组合物和方法 |
US10925977B2 (en) * | 2006-10-05 | 2021-02-23 | Ceil>Point, LLC | Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications |
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1999
- 1999-12-17 TR TR2001/01757T patent/TR200101757T2/tr unknown
- 1999-12-17 US US09/466,582 patent/US6558649B1/en not_active Expired - Fee Related
- 1999-12-17 WO PCT/US1999/030311 patent/WO2000035887A2/en active Application Filing
- 1999-12-17 CA CA002349333A patent/CA2349333A1/en not_active Abandoned
- 1999-12-17 AU AU23714/00A patent/AU2371400A/en not_active Abandoned
- 1999-12-17 EP EP99967441A patent/EP1140864A2/en not_active Withdrawn
-
2002
- 2002-11-26 US US10/306,244 patent/US6818201B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20030143235A1 (en) | 2003-07-31 |
WO2000035887A3 (en) | 2000-11-16 |
AU2371400A (en) | 2000-07-03 |
EP1140864A2 (en) | 2001-10-10 |
CA2349333A1 (en) | 2000-06-22 |
WO2000035887A2 (en) | 2000-06-22 |
US6818201B2 (en) | 2004-11-16 |
US6558649B1 (en) | 2003-05-06 |
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