TR200101703T2 - Aktif limfotoksin-ß reseptör imunoglobülin şimerik proteinlerinin yüksek düzey ifadesi ve saflaştırılması için bir yöntem. - Google Patents

Aktif limfotoksin-ß reseptör imunoglobülin şimerik proteinlerinin yüksek düzey ifadesi ve saflaştırılması için bir yöntem.

Info

Publication number
TR200101703T2
TR200101703T2 TR2001/01703T TR200101703T TR200101703T2 TR 200101703 T2 TR200101703 T2 TR 200101703T2 TR 2001/01703 T TR2001/01703 T TR 2001/01703T TR 200101703 T TR200101703 T TR 200101703T TR 200101703 T2 TR200101703 T2 TR 200101703T2
Authority
TR
Turkey
Prior art keywords
purification
level expression
chimeric proteins
receptor immunoglobulin
immunoglobulin chimeric
Prior art date
Application number
TR2001/01703T
Other languages
English (en)
Inventor
Browning Jeffrey
Miatkowski Konrad
Meier Werner
Original Assignee
Biogen, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22345666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200101703(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen, Inc. filed Critical Biogen, Inc.
Publication of TR200101703T2 publication Critical patent/TR200101703T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

Aktif limfotoksin- reseptör imunoglobülin simerik proteinlerinin yüksek düzey ifadesi ve saflastirilmasi için yöntemler.
TR2001/01703T 1998-12-17 1999-12-16 Aktif limfotoksin-ß reseptör imunoglobülin şimerik proteinlerinin yüksek düzey ifadesi ve saflaştırılması için bir yöntem. TR200101703T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11275298P 1998-12-17 1998-12-17

Publications (1)

Publication Number Publication Date
TR200101703T2 true TR200101703T2 (tr) 2002-05-21

Family

ID=22345666

Family Applications (2)

Application Number Title Priority Date Filing Date
TR2005/042202005/04220T TR200504220T2 (tr) 1998-12-17 1999-11-16 Aktif limfotoksin-beta reseptör imunoglobülin şimeAktif limfotoksin-beta reseptör imunoglobülin şimerik proteinlerinin yüksek düzey ifadesi ve saflaştrik proteinlerinin yüksek düzey ifadesi ve saflaştırılması için bir yöntem.ırılması için bir yöntem.
TR2001/01703T TR200101703T2 (tr) 1998-12-17 1999-12-16 Aktif limfotoksin-ß reseptör imunoglobülin şimerik proteinlerinin yüksek düzey ifadesi ve saflaştırılması için bir yöntem.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
TR2005/042202005/04220T TR200504220T2 (tr) 1998-12-17 1999-11-16 Aktif limfotoksin-beta reseptör imunoglobülin şimeAktif limfotoksin-beta reseptör imunoglobülin şimerik proteinlerinin yüksek düzey ifadesi ve saflaştrik proteinlerinin yüksek düzey ifadesi ve saflaştırılması için bir yöntem.ırılması için bir yöntem.

Country Status (27)

Country Link
US (3) US7585946B2 (tr)
EP (3) EP2374872B2 (tr)
JP (4) JP4878676B2 (tr)
KR (3) KR20020013482A (tr)
CN (2) CN101289512A (tr)
AT (1) ATE536372T1 (tr)
AU (2) AU777232B2 (tr)
BR (1) BR9916325B1 (tr)
CA (1) CA2354539A1 (tr)
CY (1) CY1117003T1 (tr)
CZ (1) CZ20012156A3 (tr)
DK (2) DK1141248T3 (tr)
EA (1) EA005270B1 (tr)
EE (1) EE200100324A (tr)
ES (1) ES2554482T5 (tr)
HK (2) HK1038244A1 (tr)
HU (1) HUP0200064A2 (tr)
IL (3) IL143670A0 (tr)
IS (1) IS5959A (tr)
NO (1) NO20012991L (tr)
NZ (3) NZ529276A (tr)
PT (1) PT2374872E (tr)
SG (1) SG123531A1 (tr)
SI (1) SI2374872T2 (tr)
SK (1) SK8552001A3 (tr)
TR (2) TR200504220T2 (tr)
WO (1) WO2000036092A2 (tr)

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Also Published As

Publication number Publication date
EP2374872A2 (en) 2011-10-12
AU777232B2 (en) 2004-10-07
DK2374872T3 (en) 2015-12-14
SI2374872T2 (sl) 2019-05-31
KR20060084860A (ko) 2006-07-25
AU2005200042A1 (en) 2005-02-03
BR9916325B1 (pt) 2011-06-28
HUP0200064A2 (en) 2002-05-29
EP2374872B1 (en) 2015-11-25
ES2554482T5 (es) 2019-07-18
IL205698A (en) 2015-11-30
WO2000036092A3 (en) 2000-11-23
HK1038244A1 (en) 2002-03-08
JP2003517277A (ja) 2003-05-27
KR20020013482A (ko) 2002-02-20
NO20012991L (no) 2001-08-17
SI2374872T1 (sl) 2016-03-31
NZ549623A (en) 2008-05-30
IL229738A0 (en) 2014-01-30
PL348816A1 (en) 2002-06-17
CA2354539A1 (en) 2000-06-22
US7585946B2 (en) 2009-09-08
CY1117003T1 (el) 2017-04-05
US20020039580A1 (en) 2002-04-04
EA005270B1 (ru) 2004-12-30
EP2374872B2 (en) 2019-02-20
IS5959A (is) 2001-05-31
BR9916325A (pt) 2001-10-02
EA200100670A1 (ru) 2001-12-24
AU2005200042B2 (en) 2008-05-01
WO2000036092A9 (en) 2002-08-22
JP4878676B2 (ja) 2012-02-15
EP1141248A2 (en) 2001-10-10
ATE536372T1 (de) 2011-12-15
CZ20012156A3 (cs) 2001-09-12
SK8552001A3 (en) 2001-12-03
JP2013116118A (ja) 2013-06-13
NZ538599A (en) 2007-11-30
EP2374872A3 (en) 2011-10-19
NO20012991D0 (no) 2001-06-15
EP1141248B1 (en) 2011-12-07
KR100732934B1 (ko) 2007-06-29
US8709759B2 (en) 2014-04-29
US20130196376A1 (en) 2013-08-01
AU2364400A (en) 2000-07-03
EP3006563A1 (en) 2016-04-13
EE200100324A (et) 2002-10-15
SG123531A1 (en) 2006-07-26
CN100387708C (zh) 2008-05-14
DK2374872T4 (en) 2019-04-23
ES2554482T3 (es) 2015-12-21
CN101289512A (zh) 2008-10-22
US8283138B2 (en) 2012-10-09
TR200504220T2 (tr) 2007-04-24
JP2010158252A (ja) 2010-07-22
US20100136625A1 (en) 2010-06-03
PT2374872E (pt) 2015-12-09
JP5777171B2 (ja) 2015-09-09
WO2000036092A2 (en) 2000-06-22
CN1333819A (zh) 2002-01-30
HK1223398A1 (zh) 2017-07-28
IL143670A0 (en) 2002-04-21
KR20070091227A (ko) 2007-09-07
NZ529276A (en) 2005-03-24
JP2014239697A (ja) 2014-12-25
DK1141248T3 (da) 2012-03-12

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