TR200000672T2 - Epoksit aramaddeleri hazırlamak için bir işlem. - Google Patents
Epoksit aramaddeleri hazırlamak için bir işlem.Info
- Publication number
- TR200000672T2 TR200000672T2 TR2000/00672T TR200000672T TR200000672T2 TR 200000672 T2 TR200000672 T2 TR 200000672T2 TR 2000/00672 T TR2000/00672 T TR 2000/00672T TR 200000672 T TR200000672 T TR 200000672T TR 200000672 T2 TR200000672 T2 TR 200000672T2
- Authority
- TR
- Turkey
- Prior art keywords
- heptanoate
- hydroxy
- derivatives
- preparing epoxy
- methyl
- Prior art date
Links
- 239000004593 Epoxy Substances 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- BGKHCLZFGPIKKU-UHFFFAOYSA-N (13E,15S)-15-hydroxy-9-oxo-prosta-10,13-dienoic acid Natural products CCCCCC(O)C=CC1C=CC(=O)C1CCCCCCC(O)=O BGKHCLZFGPIKKU-UHFFFAOYSA-N 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- MNWFXJYAOYHMED-UHFFFAOYSA-N heptanoic acid Chemical compound CCCCCCC(O)=O MNWFXJYAOYHMED-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000002841 Lewis acid Substances 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 150000007517 lewis acids Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 239000012038 nucleophile Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 238000007142 ring opening reaction Methods 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
Abstract
13, 14-dihidro prostaglandin A, E ve F türevlerini sentezlemeye yönelik çok uzun literatür prosedürlerinin dezavantajlarinin ticari olarak satilan Metil 7-[3-(R)-hidroksi-5-okso-1-siklopent-1-il] heptanoattan sentezlenebilen yeni bir Metil 7-(2-hidroksi-5-(2-(2-oksiranil)etil) -4-(1,1,2,2-tetrametil-1-silapropoksi) siklopentil) heptanoat aramaddesi kullanilarak ortadan kaldirilabilecegi sasirtici bir sekilde kesfedildi. Bu yeni aramadde bir bazin veya bir Lewis asitinin varliginda, bir halka açma isleminde oksijen, karbon, kükürt ve azot nükleofilleriyle baglanarak 13, 14-dihidro prostaglandin A,E ve F türevleri elde edilebilir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5825497P | 1997-09-09 | 1997-09-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200000672T2 true TR200000672T2 (tr) | 2000-07-21 |
Family
ID=22015649
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/00672T TR200000672T2 (tr) | 1997-09-09 | 1998-09-04 | Epoksit aramaddeleri hazırlamak için bir işlem. |
Country Status (16)
Country | Link |
---|---|
US (1) | US6066751A (tr) |
EP (1) | EP1012138A1 (tr) |
JP (1) | JP2001515884A (tr) |
CN (1) | CN1269783A (tr) |
AU (1) | AU9305798A (tr) |
BR (1) | BR9811771A (tr) |
CA (1) | CA2303797A1 (tr) |
HU (1) | HUP0003578A2 (tr) |
ID (1) | ID24840A (tr) |
IL (1) | IL134864A0 (tr) |
NO (1) | NO20001140L (tr) |
PE (1) | PE121499A1 (tr) |
PL (1) | PL339220A1 (tr) |
SK (1) | SK3392000A3 (tr) |
TR (1) | TR200000672T2 (tr) |
WO (1) | WO1999012897A1 (tr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4834224B2 (ja) | 1999-03-05 | 2011-12-14 | デューク ユニバーシティ | C16不飽和fp−選択的プロスタグランジン類縁体 |
US20020172693A1 (en) | 2000-03-31 | 2002-11-21 | Delong Michell Anthony | Compositions and methods for treating hair loss using non-naturally occurring prostaglandins |
US20020013294A1 (en) | 2000-03-31 | 2002-01-31 | Delong Mitchell Anthony | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives |
KR100437873B1 (ko) * | 2001-05-08 | 2004-06-26 | 연성정밀화학(주) | 프로스타글란딘 유도체의 제조방법 및 그의 입체특이적출발물질 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3776938A (en) * | 1958-05-28 | 1973-12-04 | S Bergstrom | Dihydro-pge1 |
US3505386A (en) * | 1965-12-29 | 1970-04-07 | Upjohn Co | Compounds related to prostaglandins |
US3435053A (en) * | 1966-06-06 | 1969-03-25 | Upjohn Co | Cyclopenta(b)pyrans |
-
1998
- 1998-09-04 TR TR2000/00672T patent/TR200000672T2/tr unknown
- 1998-09-04 IL IL13486498A patent/IL134864A0/xx unknown
- 1998-09-04 EP EP98945917A patent/EP1012138A1/en not_active Ceased
- 1998-09-04 ID IDW20000642A patent/ID24840A/id unknown
- 1998-09-04 BR BR9811771-8A patent/BR9811771A/pt not_active Application Discontinuation
- 1998-09-04 SK SK339-2000A patent/SK3392000A3/sk unknown
- 1998-09-04 PL PL98339220A patent/PL339220A1/xx not_active Application Discontinuation
- 1998-09-04 US US09/148,539 patent/US6066751A/en not_active Expired - Fee Related
- 1998-09-04 AU AU93057/98A patent/AU9305798A/en not_active Abandoned
- 1998-09-04 CA CA002303797A patent/CA2303797A1/en not_active Abandoned
- 1998-09-04 HU HU0003578A patent/HUP0003578A2/hu unknown
- 1998-09-04 JP JP2000510709A patent/JP2001515884A/ja not_active Withdrawn
- 1998-09-04 CN CN98808986A patent/CN1269783A/zh active Pending
- 1998-09-04 WO PCT/US1998/018593 patent/WO1999012897A1/en not_active Application Discontinuation
- 1998-10-02 PE PE1998000932A patent/PE121499A1/es not_active Application Discontinuation
-
2000
- 2000-03-06 NO NO20001140A patent/NO20001140L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BR9811771A (pt) | 2000-08-29 |
SK3392000A3 (en) | 2000-09-12 |
ID24840A (id) | 2000-08-24 |
PL339220A1 (en) | 2000-12-04 |
HUP0003578A2 (hu) | 2001-02-28 |
CN1269783A (zh) | 2000-10-11 |
WO1999012897A1 (en) | 1999-03-18 |
PE121499A1 (es) | 2000-02-03 |
US6066751A (en) | 2000-05-23 |
NO20001140L (no) | 2000-05-04 |
EP1012138A1 (en) | 2000-06-28 |
AU9305798A (en) | 1999-03-29 |
JP2001515884A (ja) | 2001-09-25 |
IL134864A0 (en) | 2001-05-20 |
NO20001140D0 (no) | 2000-03-06 |
CA2303797A1 (en) | 1999-03-18 |
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