TR199801644T2 - Oksa- ve tiya-diazol içeren muskarinik reseptör antagonistleri - Google Patents
Oksa- ve tiya-diazol içeren muskarinik reseptör antagonistleriInfo
- Publication number
- TR199801644T2 TR199801644T2 TR1998/01644T TR9801644T TR199801644T2 TR 199801644 T2 TR199801644 T2 TR 199801644T2 TR 1998/01644 T TR1998/01644 T TR 1998/01644T TR 9801644 T TR9801644 T TR 9801644T TR 199801644 T2 TR199801644 T2 TR 199801644T2
- Authority
- TR
- Turkey
- Prior art keywords
- alkyl
- muscarinic receptor
- oxave
- iéeren
- tiya
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Asagidaki (1) formülüne sahip bir bilesik ya da bunun, ilaç sanayiinde kullanilmaya uygun bir tuzu: FORMÜL yukaridaki formülde R1, C1-C6 alkil, halo-(C1-C6 alkil), C3-C7 sikloalkil, C2-C6 alkinil, hidroksi-(C2-C6 alkinil), (C1-C4 alkoksi)-(C2-C6 alkinil), aril, aril-(C1-C4 alkil), heteroaril ya da heteroaril-(C1-C4 alkil)'dir; R2, H ya da C1-C4 alkil'dir; R3, aril, heteroaril, 2,3-dihidrobenzofuranil ya da C4-C7 sikloalkil'dir; X, O ya da S'dir ve Y, bir dogrudan bag, -CH2-, -(CH2)- ya da -CH2O-'dur. Bilesikler, sözgelimi kolaylikla tahris olabilen bagirsak sendromu ve idrar tutamama gibi rahatsizliklarin tedavisinde yararli olan muskarinik reseptör antagonistleridir. Bilesikler ayrica, idrak güçlendirici maddeler olarak da yararlidir
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9603755.1A GB9603755D0 (en) | 1996-02-22 | 1996-02-22 | Therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199801644T2 true TR199801644T2 (tr) | 1998-11-23 |
Family
ID=10789217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR1998/01644T TR199801644T2 (tr) | 1996-02-22 | 1997-02-04 | Oksa- ve tiya-diazol içeren muskarinik reseptör antagonistleri |
Country Status (43)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6107313A (en) * | 1998-10-02 | 2000-08-22 | Combichem, Inc. | Dopamine receptor antagonists |
| GB0510139D0 (en) * | 2005-05-18 | 2005-06-22 | Addex Pharmaceuticals Sa | Novel compounds B1 |
| GB0510141D0 (en) * | 2005-05-18 | 2005-06-22 | Addex Pharmaceuticals Sa | Novel compounds B3 |
| GB0516313D0 (en) | 2005-08-08 | 2005-09-14 | Argenta Discovery Ltd | Azole derivatives and their uses |
| WO2008017827A2 (en) * | 2006-08-08 | 2008-02-14 | Argenta Discovery Limited | Azole and thiazole derivatives and their uses |
| JP2010501533A (ja) * | 2006-08-21 | 2010-01-21 | アージェンタ ディスカバリー リミテッド | Ｍ３レセプター調節物質として有用な窒素含有複素環化合物 |
| WO2008096093A1 (en) * | 2007-02-06 | 2008-08-14 | Argenta Discovery Ltd. | Oxazole and thiazole derivatives and their uses |
| JP5373634B2 (ja) * | 2007-02-07 | 2013-12-18 | パルメイゲン・セラピューティクス・（シナジー）・リミテッド | ムスカリンｍ３アンタゴニストのナパジシル酸塩 |
| GB0702416D0 (en) * | 2007-02-07 | 2007-03-21 | Argenta Discovery Ltd | New combination |
| GB0702382D0 (en) * | 2007-02-07 | 2007-03-21 | Argenta Discovery Ltd | New salt |
| GB0702414D0 (en) * | 2007-02-07 | 2007-03-21 | Argenta Discovery Ltd | Oxazole and thiazole derivatives and their uses 2 |
| GB0702385D0 (en) * | 2007-02-07 | 2007-03-21 | Argenta Discovery Ltd | New combination |
| EP2121688A1 (en) * | 2007-02-15 | 2009-11-25 | Argenta Discovery Ltd | Heterocyclic derivatives as m3 muscarinic receptors |
| WO2009098453A1 (en) * | 2008-02-06 | 2009-08-13 | Astrazeneca Ab | Azonia bicycloalkanes as m3 muscarinic acetylcholin receptor antagonists |
| US8263623B2 (en) | 2008-07-11 | 2012-09-11 | Pfizer Inc. | Triazol derivatives useful for the treatment of diseases |
| WO2010018352A1 (en) * | 2008-08-12 | 2010-02-18 | Argenta Discovery Limited | Heterocyclic compounds used in the treatment of diseases where enhanced m3 receptor activation is implicated |
| JP2014065387A (ja) * | 2012-09-25 | 2014-04-17 | Showa Corp | 自動二輪車の車高調整装置 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ219646A (en) * | 1986-03-27 | 1990-10-26 | Merck Sharp & Dohme | Oxadiazole derivatives of azacyclics for treating cns disorders |
| IL88846A0 (en) * | 1988-01-08 | 1989-07-31 | Merck Sharp & Dohme | Lipophilic oxadiazoles,their preparation and pharmaceutical compositions containing them |
| US5043345A (en) * | 1989-02-22 | 1991-08-27 | Novo Nordisk A/S | Piperidine compounds and their preparation and use |
| US5622976A (en) * | 1991-12-31 | 1997-04-22 | Fujisawa Pharmaceutical Co., Ltd. | Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity |
| TW360653B (en) * | 1995-03-01 | 1999-06-11 | Janssen Pharmaceutica Nv | A oxadiazole compound having colon motility stimulating properties, its preparation process and its pharmaceutical composition |
-
1996
- 1996-02-22 GB GBGB9603755.1A patent/GB9603755D0/en active Pending
-
1997
- 1997-01-21 TW TW086100642A patent/TW492961B/zh not_active IP Right Cessation
- 1997-02-03 HN HN1997000020A patent/HN1997000020A/es unknown
- 1997-02-04 AU AU16014/97A patent/AU712230B2/en not_active Ceased
- 1997-02-04 TR TR1998/01644T patent/TR199801644T2/tr unknown
- 1997-02-04 RU RU98117457/04A patent/RU2162848C2/ru not_active IP Right Cessation
- 1997-02-04 ES ES97902337T patent/ES2156357T3/es not_active Expired - Lifetime
- 1997-02-04 CN CN97192486A patent/CN1089340C/zh not_active Expired - Fee Related
- 1997-02-04 CA CA002247164A patent/CA2247164C/en not_active Expired - Fee Related
- 1997-02-04 HU HU9900501A patent/HUP9900501A3/hu unknown
- 1997-02-04 KR KR1019980706534A patent/KR100315934B1/ko not_active IP Right Cessation
- 1997-02-04 DK DK97902337T patent/DK0885218T3/da active
- 1997-02-04 PT PT97902337T patent/PT885218E/pt unknown
- 1997-02-04 CZ CZ19982678A patent/CZ292650B6/cs not_active IP Right Cessation
- 1997-02-04 DE DE69704701T patent/DE69704701T2/de not_active Expired - Fee Related
- 1997-02-04 WO PCT/EP1997/000525 patent/WO1997030994A1/en active IP Right Grant
- 1997-02-04 NZ NZ331039A patent/NZ331039A/en unknown
- 1997-02-04 JP JP52974197A patent/JP3148252B2/ja not_active Expired - Fee Related
- 1997-02-04 IL IL12541397A patent/IL125413A/en not_active IP Right Cessation
- 1997-02-04 US US09/117,556 patent/US5977142A/en not_active Expired - Fee Related
- 1997-02-04 BR BR9707733A patent/BR9707733A/pt not_active Application Discontinuation
- 1997-02-04 AT AT97902337T patent/ATE200899T1/de not_active IP Right Cessation
- 1997-02-04 PL PL97328633A patent/PL186879B1/pl not_active IP Right Cessation
- 1997-02-04 SK SK1123-98A patent/SK283461B6/sk unknown
- 1997-02-04 EP EP97902337A patent/EP0885218B1/en not_active Expired - Lifetime
- 1997-02-13 CO CO97007550A patent/CO4650040A1/es unknown
- 1997-02-14 PE PE1997000104A patent/PE42798A1/es not_active Application Discontinuation
- 1997-02-19 DZ DZ970027A patent/DZ2181A1/fr active
- 1997-02-19 TN TNTNSN97039A patent/TNSN97039A1/fr unknown
- 1997-02-20 AR ARP970100667A patent/AR005916A1/es unknown
- 1997-02-20 AP APAP/P/1997/000930A patent/AP751A/en active
- 1997-02-20 HR HR970098A patent/HRP970098B1/xx not_active IP Right Cessation
- 1997-02-21 MY MYPI97000654A patent/MY129729A/en unknown
- 1997-02-21 ZA ZA971513A patent/ZA971513B/xx unknown
- 1997-02-21 ID IDP970521A patent/ID16642A/id unknown
- 1997-04-02 UA UA98094939A patent/UA61068C2/uk unknown
-
1998
- 1998-07-21 IS IS4803A patent/IS4803A/is unknown
- 1998-08-14 OA OA9800143A patent/OA10838A/en unknown
- 1998-08-19 BG BG102699A patent/BG63971B1/bg unknown
- 1998-08-19 BG BG102699A patent/BG102699A/xx unknown
- 1998-08-21 YU YU35698A patent/YU35698A/sh unknown
- 1998-08-21 NO NO19983871A patent/NO313414B1/no not_active IP Right Cessation
-
1999
- 1999-08-05 HK HK99103379A patent/HK1018274A1/xx not_active IP Right Cessation
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2001
- 2001-06-13 GR GR20010400885T patent/GR3036032T3/el not_active IP Right Cessation
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