HRP970098B1 - Oxa- and thia-diazole muscarinic receptor antagonists - Google Patents

Oxa- and thia-diazole muscarinic receptor antagonists

Info

Publication number
HRP970098B1
HRP970098B1 HR970098A HRP970098A HRP970098B1 HR P970098 B1 HRP970098 B1 HR P970098B1 HR 970098 A HR970098 A HR 970098A HR P970098 A HRP970098 A HR P970098A HR P970098 B1 HRP970098 B1 HR P970098B1
Authority
HR
Croatia
Prior art keywords
diazole
thia
oxa
receptor antagonists
muscarinic receptor
Prior art date
Application number
HR970098A
Other languages
English (en)
Inventor
Alexander Roderick Mackenzie
Anthony Wood
Robert John Bass
Original Assignee
Pfizer Res And Dev Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Res And Dev Company filed Critical Pfizer Res And Dev Company
Publication of HRP970098A2 publication Critical patent/HRP970098A2/hr
Publication of HRP970098B1 publication Critical patent/HRP970098B1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
HR970098A 1996-02-22 1997-02-20 Oxa- and thia-diazole muscarinic receptor antagonists HRP970098B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9603755.1A GB9603755D0 (en) 1996-02-22 1996-02-22 Therapeutic agents

Publications (2)

Publication Number Publication Date
HRP970098A2 HRP970098A2 (en) 1999-04-30
HRP970098B1 true HRP970098B1 (en) 2001-12-31

Family

ID=10789217

Family Applications (1)

Application Number Title Priority Date Filing Date
HR970098A HRP970098B1 (en) 1996-02-22 1997-02-20 Oxa- and thia-diazole muscarinic receptor antagonists

Country Status (43)

Country Link
US (1) US5977142A (xx)
EP (1) EP0885218B1 (xx)
JP (1) JP3148252B2 (xx)
KR (1) KR100315934B1 (xx)
CN (1) CN1089340C (xx)
AP (1) AP751A (xx)
AR (1) AR005916A1 (xx)
AT (1) ATE200899T1 (xx)
AU (1) AU712230B2 (xx)
BG (2) BG63971B1 (xx)
BR (1) BR9707733A (xx)
CA (1) CA2247164C (xx)
CO (1) CO4650040A1 (xx)
CZ (1) CZ292650B6 (xx)
DE (1) DE69704701T2 (xx)
DK (1) DK0885218T3 (xx)
DZ (1) DZ2181A1 (xx)
ES (1) ES2156357T3 (xx)
GB (1) GB9603755D0 (xx)
GR (1) GR3036032T3 (xx)
HK (1) HK1018274A1 (xx)
HN (1) HN1997000020A (xx)
HR (1) HRP970098B1 (xx)
HU (1) HUP9900501A3 (xx)
ID (1) ID16642A (xx)
IL (1) IL125413A (xx)
IS (1) IS4803A (xx)
MY (1) MY129729A (xx)
NO (1) NO313414B1 (xx)
NZ (1) NZ331039A (xx)
OA (1) OA10838A (xx)
PE (1) PE42798A1 (xx)
PL (1) PL186879B1 (xx)
PT (1) PT885218E (xx)
RU (1) RU2162848C2 (xx)
SK (1) SK283461B6 (xx)
TN (1) TNSN97039A1 (xx)
TR (1) TR199801644T2 (xx)
TW (1) TW492961B (xx)
UA (1) UA61068C2 (xx)
WO (1) WO1997030994A1 (xx)
YU (1) YU35698A (xx)
ZA (1) ZA971513B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
GB0510141D0 (en) * 2005-05-18 2005-06-22 Addex Pharmaceuticals Sa Novel compounds B3
GB0510139D0 (en) * 2005-05-18 2005-06-22 Addex Pharmaceuticals Sa Novel compounds B1
GB0516313D0 (en) 2005-08-08 2005-09-14 Argenta Discovery Ltd Azole derivatives and their uses
WO2008017827A2 (en) * 2006-08-08 2008-02-14 Argenta Discovery Limited Azole and thiazole derivatives and their uses
WO2008023157A1 (en) * 2006-08-21 2008-02-28 Argenta Discovery Limited Nitrogen containing heterocyclic compounds useful as m3-receptor modulators
WO2008096093A1 (en) * 2007-02-06 2008-08-14 Argenta Discovery Ltd. Oxazole and thiazole derivatives and their uses
GB0702414D0 (en) * 2007-02-07 2007-03-21 Argenta Discovery Ltd Oxazole and thiazole derivatives and their uses 2
GB0702416D0 (en) * 2007-02-07 2007-03-21 Argenta Discovery Ltd New combination
BRPI0807004A2 (pt) * 2007-02-07 2014-04-15 Argenta Discovery Ltd Sal
GB0702382D0 (en) * 2007-02-07 2007-03-21 Argenta Discovery Ltd New salt
GB0702385D0 (en) * 2007-02-07 2007-03-21 Argenta Discovery Ltd New combination
RU2009133258A (ru) * 2007-02-15 2011-03-20 Арджента Дискавери Лимитед (Gb) Гетероциклические производные в качестве ингибиторов мускариновых рецепторов типа мз
WO2009098453A1 (en) * 2008-02-06 2009-08-13 Astrazeneca Ab Azonia bicycloalkanes as m3 muscarinic acetylcholin receptor antagonists
US8263623B2 (en) 2008-07-11 2012-09-11 Pfizer Inc. Triazol derivatives useful for the treatment of diseases
WO2010018352A1 (en) * 2008-08-12 2010-02-18 Argenta Discovery Limited Heterocyclic compounds used in the treatment of diseases where enhanced m3 receptor activation is implicated
JP2014065387A (ja) * 2012-09-25 2014-04-17 Showa Corp 自動二輪車の車高調整装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
IL88846A0 (en) * 1988-01-08 1989-07-31 Merck Sharp & Dohme Lipophilic oxadiazoles,their preparation and pharmaceutical compositions containing them
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
EP0619814A1 (en) * 1991-12-31 1994-10-19 Fujisawa Pharmaceutical Co., Ltd. Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity
TW360653B (en) * 1995-03-01 1999-06-11 Janssen Pharmaceutica Nv A oxadiazole compound having colon motility stimulating properties, its preparation process and its pharmaceutical composition

Also Published As

Publication number Publication date
ZA971513B (en) 1998-08-21
PT885218E (pt) 2001-08-30
KR19990087143A (ko) 1999-12-15
TNSN97039A1 (fr) 2005-03-15
TW492961B (en) 2002-07-01
NZ331039A (en) 1999-10-28
BG63971B1 (bg) 2003-08-29
KR100315934B1 (ko) 2002-03-21
BG102699A (en) 1999-09-30
CO4650040A1 (es) 1998-09-03
ATE200899T1 (de) 2001-05-15
ID16642A (id) 1997-10-23
HUP9900501A2 (hu) 1999-06-28
DE69704701T2 (de) 2001-08-16
SK283461B6 (sk) 2003-08-05
DE69704701D1 (de) 2001-06-07
DZ2181A1 (fr) 2002-12-01
GB9603755D0 (en) 1996-04-24
MY129729A (en) 2007-04-30
OA10838A (en) 2001-08-13
CA2247164C (en) 2004-11-16
PL328633A1 (en) 1999-02-15
CN1211981A (zh) 1999-03-24
AR005916A1 (es) 1999-07-21
PE42798A1 (es) 1998-08-18
WO1997030994A1 (en) 1997-08-28
TR199801644T2 (xx) 1998-11-23
UA61068C2 (en) 2003-11-17
EP0885218B1 (en) 2001-05-02
JPH11504051A (ja) 1999-04-06
AU712230B2 (en) 1999-11-04
NO983871L (no) 1998-08-21
ES2156357T3 (es) 2001-06-16
YU35698A (sh) 1999-07-28
NO313414B1 (no) 2002-09-30
HN1997000020A (es) 1997-06-05
CZ292650B6 (cs) 2003-11-12
CZ267898A3 (cs) 1999-08-11
HRP970098A2 (en) 1999-04-30
BR9707733A (pt) 1999-07-27
IL125413A (en) 2002-09-12
EP0885218A1 (en) 1998-12-23
AP9700930A0 (en) 1997-04-30
PL186879B1 (pl) 2004-03-31
IL125413A0 (en) 1999-03-12
HK1018274A1 (en) 1999-12-17
AP751A (en) 1999-07-12
AU1601497A (en) 1997-09-10
JP3148252B2 (ja) 2001-03-19
NO983871D0 (no) 1998-08-21
HUP9900501A3 (en) 2001-02-28
DK0885218T3 (da) 2001-05-28
IS4803A (is) 1998-07-21
US5977142A (en) 1999-11-02
CN1089340C (zh) 2002-08-21
SK112398A3 (en) 2000-04-10
CA2247164A1 (en) 1997-08-28
RU2162848C2 (ru) 2001-02-10
GR3036032T3 (en) 2001-09-28

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Legal Events

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Payment date: 20040119

Year of fee payment: 8

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Effective date: 20050221