OA10838A - Oxa-and thia-diazole muscarinic receptor antagonists - Google Patents

Oxa-and thia-diazole muscarinic receptor antagonists Download PDF

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Publication number
OA10838A
OA10838A OA9800143A OA9800143A OA10838A OA 10838 A OA10838 A OA 10838A OA 9800143 A OA9800143 A OA 9800143A OA 9800143 A OA9800143 A OA 9800143A OA 10838 A OA10838 A OA 10838A
Authority
OA
OAPI
Prior art keywords
compound
formula
alkyl
daim
crc4
Prior art date
Application number
OA9800143A
Other languages
English (en)
Inventor
Alexander Roderick Mackenzie
Robert John Bass
Anthony Wood
Original Assignee
Pfizer Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Res & Dev filed Critical Pfizer Res & Dev
Publication of OA10838A publication Critical patent/OA10838A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
OA9800143A 1996-02-22 1998-08-14 Oxa-and thia-diazole muscarinic receptor antagonists OA10838A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9603755.1A GB9603755D0 (en) 1996-02-22 1996-02-22 Therapeutic agents

Publications (1)

Publication Number Publication Date
OA10838A true OA10838A (en) 2001-08-13

Family

ID=10789217

Family Applications (1)

Application Number Title Priority Date Filing Date
OA9800143A OA10838A (en) 1996-02-22 1998-08-14 Oxa-and thia-diazole muscarinic receptor antagonists

Country Status (43)

Country Link
US (1) US5977142A (xx)
EP (1) EP0885218B1 (xx)
JP (1) JP3148252B2 (xx)
KR (1) KR100315934B1 (xx)
CN (1) CN1089340C (xx)
AP (1) AP751A (xx)
AR (1) AR005916A1 (xx)
AT (1) ATE200899T1 (xx)
AU (1) AU712230B2 (xx)
BG (2) BG63971B1 (xx)
BR (1) BR9707733A (xx)
CA (1) CA2247164C (xx)
CO (1) CO4650040A1 (xx)
CZ (1) CZ292650B6 (xx)
DE (1) DE69704701T2 (xx)
DK (1) DK0885218T3 (xx)
DZ (1) DZ2181A1 (xx)
ES (1) ES2156357T3 (xx)
GB (1) GB9603755D0 (xx)
GR (1) GR3036032T3 (xx)
HK (1) HK1018274A1 (xx)
HN (1) HN1997000020A (xx)
HR (1) HRP970098B1 (xx)
HU (1) HUP9900501A3 (xx)
ID (1) ID16642A (xx)
IL (1) IL125413A (xx)
IS (1) IS4803A (xx)
MY (1) MY129729A (xx)
NO (1) NO313414B1 (xx)
NZ (1) NZ331039A (xx)
OA (1) OA10838A (xx)
PE (1) PE42798A1 (xx)
PL (1) PL186879B1 (xx)
PT (1) PT885218E (xx)
RU (1) RU2162848C2 (xx)
SK (1) SK283461B6 (xx)
TN (1) TNSN97039A1 (xx)
TR (1) TR199801644T2 (xx)
TW (1) TW492961B (xx)
UA (1) UA61068C2 (xx)
WO (1) WO1997030994A1 (xx)
YU (1) YU35698A (xx)
ZA (1) ZA971513B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
GB0510139D0 (en) * 2005-05-18 2005-06-22 Addex Pharmaceuticals Sa Novel compounds B1
GB0510141D0 (en) * 2005-05-18 2005-06-22 Addex Pharmaceuticals Sa Novel compounds B3
GB0516313D0 (en) 2005-08-08 2005-09-14 Argenta Discovery Ltd Azole derivatives and their uses
WO2008017827A2 (en) * 2006-08-08 2008-02-14 Argenta Discovery Limited Azole and thiazole derivatives and their uses
JP2010501533A (ja) * 2006-08-21 2010-01-21 アージェンタ ディスカバリー リミテッド Ｍ３レセプター調節物質として有用な窒素含有複素環化合物
WO2008096093A1 (en) * 2007-02-06 2008-08-14 Argenta Discovery Ltd. Oxazole and thiazole derivatives and their uses
JP5373634B2 (ja) * 2007-02-07 2013-12-18 パルメイゲン・セラピューティクス・（シナジー）・リミテッド ムスカリンｍ３アンタゴニストのナパジシル酸塩
GB0702416D0 (en) * 2007-02-07 2007-03-21 Argenta Discovery Ltd New combination
GB0702382D0 (en) * 2007-02-07 2007-03-21 Argenta Discovery Ltd New salt
GB0702414D0 (en) * 2007-02-07 2007-03-21 Argenta Discovery Ltd Oxazole and thiazole derivatives and their uses 2
GB0702385D0 (en) * 2007-02-07 2007-03-21 Argenta Discovery Ltd New combination
EP2121688A1 (en) * 2007-02-15 2009-11-25 Argenta Discovery Ltd Heterocyclic derivatives as m3 muscarinic receptors
WO2009098453A1 (en) * 2008-02-06 2009-08-13 Astrazeneca Ab Azonia bicycloalkanes as m3 muscarinic acetylcholin receptor antagonists
US8263623B2 (en) 2008-07-11 2012-09-11 Pfizer Inc. Triazol derivatives useful for the treatment of diseases
WO2010018352A1 (en) * 2008-08-12 2010-02-18 Argenta Discovery Limited Heterocyclic compounds used in the treatment of diseases where enhanced m3 receptor activation is implicated
JP2014065387A (ja) * 2012-09-25 2014-04-17 Showa Corp 自動二輪車の車高調整装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
IL88846A0 (en) * 1988-01-08 1989-07-31 Merck Sharp & Dohme Lipophilic oxadiazoles,their preparation and pharmaceutical compositions containing them
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
US5622976A (en) * 1991-12-31 1997-04-22 Fujisawa Pharmaceutical Co., Ltd. Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity
TW360653B (en) * 1995-03-01 1999-06-11 Janssen Pharmaceutica Nv A oxadiazole compound having colon motility stimulating properties, its preparation process and its pharmaceutical composition

Also Published As

Publication number Publication date
ES2156357T3 (es) 2001-06-16
CA2247164C (en) 2004-11-16
AU1601497A (en) 1997-09-10
CZ267898A3 (cs) 1999-08-11
BG63971B1 (bg) 2003-08-29
ATE200899T1 (de) 2001-05-15
DE69704701T2 (de) 2001-08-16
CO4650040A1 (es) 1998-09-03
CZ292650B6 (cs) 2003-11-12
AR005916A1 (es) 1999-07-21
TNSN97039A1 (fr) 2005-03-15
PL186879B1 (pl) 2004-03-31
HUP9900501A3 (en) 2001-02-28
BG102699A (en) 1999-09-30
KR100315934B1 (ko) 2002-03-21
JP3148252B2 (ja) 2001-03-19
DK0885218T3 (da) 2001-05-28
YU35698A (sh) 1999-07-28
SK112398A3 (en) 2000-04-10
NO313414B1 (no) 2002-09-30
GB9603755D0 (en) 1996-04-24
RU2162848C2 (ru) 2001-02-10
NZ331039A (en) 1999-10-28
ZA971513B (en) 1998-08-21
IL125413A (en) 2002-09-12
PL328633A1 (en) 1999-02-15
PT885218E (pt) 2001-08-30
WO1997030994A1 (en) 1997-08-28
CN1089340C (zh) 2002-08-21
AP9700930A0 (en) 1997-04-30
BR9707733A (pt) 1999-07-27
DE69704701D1 (de) 2001-06-07
TW492961B (en) 2002-07-01
US5977142A (en) 1999-11-02
HN1997000020A (es) 1997-06-05
EP0885218B1 (en) 2001-05-02
ID16642A (id) 1997-10-23
NO983871L (no) 1998-08-21
PE42798A1 (es) 1998-08-18
IS4803A (is) 1998-07-21
CA2247164A1 (en) 1997-08-28
HK1018274A1 (en) 1999-12-17
EP0885218A1 (en) 1998-12-23
JPH11504051A (ja) 1999-04-06
IL125413A0 (en) 1999-03-12
GR3036032T3 (en) 2001-09-28
CN1211981A (zh) 1999-03-24
TR199801644T2 (xx) 1998-11-23
HRP970098A2 (en) 1999-04-30
UA61068C2 (en) 2003-11-17
AP751A (en) 1999-07-12
SK283461B6 (sk) 2003-08-05
DZ2181A1 (fr) 2002-12-01
HRP970098B1 (en) 2001-12-31
AU712230B2 (en) 1999-11-04
KR19990087143A (ko) 1999-12-15
MY129729A (en) 2007-04-30
NO983871D0 (no) 1998-08-21
HUP9900501A2 (hu) 1999-06-28

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