TNSN99114A1 - Oxo-thia-azabicyclooctenes, preparations pharmaceutiques les contenant, et leur utilisation pour le traitement et la prophylaxie de maladies infectieuses - Google Patents

Oxo-thia-azabicyclooctenes, preparations pharmaceutiques les contenant, et leur utilisation pour le traitement et la prophylaxie de maladies infectieuses

Info

Publication number
TNSN99114A1
TNSN99114A1 TNTNSN99114A TNSN99114A TNSN99114A1 TN SN99114 A1 TNSN99114 A1 TN SN99114A1 TN TNSN99114 A TNTNSN99114 A TN TNSN99114A TN SN99114 A TNSN99114 A TN SN99114A TN SN99114 A1 TNSN99114 A1 TN SN99114A1
Authority
TN
Tunisia
Prior art keywords
compounds
hydrogen atom
ocor
group
salts
Prior art date
Application number
TNTNSN99114A
Other languages
English (en)
French (fr)
Inventor
Hebeisen Paul
Hubschwerlen Christian
Specklin Jean-Luc
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of TNSN99114A1 publication Critical patent/TNSN99114A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/48Methylene radicals, substituted by hetero rings
    • C07D501/56Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TNTNSN99114A 1998-06-15 1999-06-15 Oxo-thia-azabicyclooctenes, preparations pharmaceutiques les contenant, et leur utilisation pour le traitement et la prophylaxie de maladies infectieuses TNSN99114A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98110888 1998-06-15
EP98117099 1998-09-10

Publications (1)

Publication Number Publication Date
TNSN99114A1 true TNSN99114A1 (fr) 2005-11-10

Family

ID=26149347

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN99114A TNSN99114A1 (fr) 1998-06-15 1999-06-15 Oxo-thia-azabicyclooctenes, preparations pharmaceutiques les contenant, et leur utilisation pour le traitement et la prophylaxie de maladies infectieuses

Country Status (28)

Country Link
EP (1) EP1087980B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP3872955B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100411915B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1136222C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR018675A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE231871T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU754732B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE2014C034I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (2) BRPI9911178C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2334568C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CO (1) CO5080758A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69905162T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK1087980T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2190222T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR14C0044I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GT (1) GT199900084A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HUP0105426A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ID (1) ID27686A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL139872A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU92564I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MA (1) MA26650A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO20006350D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PA (1) PA8475701A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PE (1) PE20000645A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL344994A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SV (1) SV1999000075A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TN (1) TNSN99114A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1999065920A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6267100A (en) * 1999-07-07 2001-01-30 F. Hoffmann-La Roche Ag Vinylpyrrolidinone derivatives with substituted thiazole ring
DE60123513T2 (de) 2000-04-19 2007-05-10 Basilea Pharmaceutica Ag Verfahren zur Herstellung von D-Asparaginderivaten
US6504025B2 (en) * 2000-05-24 2003-01-07 Basilea Pharmaceutica Ag Process for the preparation of vinyl-pyrrolidinone cephalosporin derivatives
PT1606293E (pt) * 2003-03-27 2009-10-14 Basilea Pharmaceutica Ag Cefalosporina sob forma cristalina
EP1656930A1 (en) * 2004-11-10 2006-05-17 Basilea Pharmaceutica AG Stabilized freeze-dried formulation for cephalosporin derivatives
AR071318A1 (es) 2008-04-15 2010-06-09 Basilea Pharmaceutica Ag Benzhidril ester del acido (6r,7r)-7-{2-(5-amino-[1,2,4]tiadiazol-3-il)-2-[(z)-tritiloxiimino]-acetilamino}-3-[(r)-1'-terc-butoxicarbonil-2-oxo-[1,3']bipirrolidinil-(3e)-ilidenometil]-8-oxo-5-tia-1-aza-biciclo[4.2.0]oct-2-eno-2-carboxilico cristalino; su elaboracion y uso
WO2010072672A1 (en) 2008-12-24 2010-07-01 Basilea Pharmaceutica Ag New crystal polymorphs of ceftobiprole
US9096610B2 (en) 2009-05-25 2015-08-04 Sandoz Ag Method for the production of ceftobiprole medocaril
PT2569321E (pt) 2010-05-10 2015-05-25 Basilea Pharmaceutica Int Ltd Processo de oxidação para a preparação de derivados 3-formil cefeme

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0841339B1 (en) * 1996-11-06 2007-02-21 Basilea Pharmaceutica AG Vinylpyrrolidinon cephalosporin derivatives
TW415949B (en) * 1996-12-19 2000-12-21 Hoffmann La Roche Vinyl pyrrolidine cephalosporin derivatives with basic substituents

Also Published As

Publication number Publication date
FR14C0044I1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2014-07-18
LU92564I2 (fr) 2014-12-01
SV1999000075A (es) 2000-05-02
BRPI9911178B8 (pt) 2017-03-07
HUP0105426A2 (hu) 2002-05-29
BR9911178B1 (pt) 2013-10-29
PL344994A1 (en) 2001-11-19
EP1087980A1 (en) 2001-04-04
AU754732B2 (en) 2002-11-21
JP2002518401A (ja) 2002-06-25
BR9911178A (pt) 2001-03-13
CA2334568C (en) 2009-02-24
BRPI9911178C1 (pt) 2021-05-25
ES2190222T3 (es) 2003-07-16
CN1136222C (zh) 2004-01-28
DK1087980T3 (da) 2003-05-26
NO20006350L (no) 2000-12-13
KR20010052866A (ko) 2001-06-25
CA2334568A1 (en) 1999-12-23
NO20006350D0 (no) 2000-12-13
JP3872955B2 (ja) 2007-01-24
ID27686A (id) 2001-04-19
AU4508199A (en) 2000-01-05
BE2014C034I2 (en) 2018-08-24
WO1999065920A1 (en) 1999-12-23
AR018675A1 (es) 2001-11-28
KR100411915B1 (ko) 2003-12-18
CO5080758A1 (es) 2001-09-25
DE69905162D1 (de) 2003-03-06
EP1087980B1 (en) 2003-01-29
MA26650A1 (fr) 2004-12-20
IL139872A0 (en) 2002-02-10
GT199900084A (es) 2000-12-05
DE69905162T2 (de) 2003-12-24
HUP0105426A3 (en) 2002-12-28
ATE231871T1 (de) 2003-02-15
PE20000645A1 (es) 2000-07-26
PA8475701A1 (es) 2000-09-29
CN1305484A (zh) 2001-07-25
FR14C0044I2 (fr) 2015-02-20

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