TNSN99035A1 - NOUVEAUX PROCEDES POUR LA PREPARATION DE (R) - α - ( 2,3 DIMETHOXYPHENYL) -1 - [ 2 - (4 - FLUOROPHENYL) ETHYL] - 4 - PIPERIDINEMETHANOL - Google Patents
NOUVEAUX PROCEDES POUR LA PREPARATION DE (R) - α - ( 2,3 DIMETHOXYPHENYL) -1 - [ 2 - (4 - FLUOROPHENYL) ETHYL] - 4 - PIPERIDINEMETHANOLInfo
- Publication number
- TNSN99035A1 TNSN99035A1 TNTNSN99035A TNSN99035A TNSN99035A1 TN SN99035 A1 TNSN99035 A1 TN SN99035A1 TN TNSN99035 A TNTNSN99035 A TN TNSN99035A TN SN99035 A TNSN99035 A TN SN99035A TN SN99035 A1 TNSN99035 A1 TN SN99035A1
- Authority
- TN
- Tunisia
- Prior art keywords
- piperidinemethanol
- dimethoxyphenyl
- fluorophenyl
- ethyl
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Abstract
LA PRESENTE INVENTION MET A DISPOSITION DIVERS PROCEDES POUR LA PREPARATION DE (R) – α - (2,3 - DIMETHOXYPHENYL)- 1 - [2 - (4 - FLUOROPHENYL) ETHYL] - 4 - PIPERIDINEMETHANOL. CES PROCEDES PEUVENT ETRE CARACTERISES PAR LE SCHEMA SUIVANT
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4225198A | 1998-03-13 | 1998-03-13 | |
US25071899A | 1999-02-16 | 1999-02-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
TNSN99035A1 true TNSN99035A1 (fr) | 2005-11-10 |
Family
ID=26719032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TNTNSN99035A TNSN99035A1 (fr) | 1998-03-13 | 1999-03-11 | NOUVEAUX PROCEDES POUR LA PREPARATION DE (R) - α - ( 2,3 DIMETHOXYPHENYL) -1 - [ 2 - (4 - FLUOROPHENYL) ETHYL] - 4 - PIPERIDINEMETHANOL |
Country Status (25)
Country | Link |
---|---|
EP (3) | EP1734037A3 (fr) |
JP (2) | JP4511723B2 (fr) |
KR (7) | KR100591643B1 (fr) |
CN (1) | CN100436415C (fr) |
AR (1) | AR015540A1 (fr) |
AT (1) | ATE373639T1 (fr) |
AU (1) | AU755436B2 (fr) |
BR (1) | BR9909260A (fr) |
CA (1) | CA2322501C (fr) |
CY (1) | CY1107104T1 (fr) |
DE (1) | DE69937162T2 (fr) |
DK (1) | DK1192134T3 (fr) |
DZ (1) | DZ2742A1 (fr) |
EG (1) | EG24052A (fr) |
ES (1) | ES2294838T3 (fr) |
HK (1) | HK1042484B (fr) |
HU (1) | HUP0400889A3 (fr) |
IL (3) | IL138307A0 (fr) |
MA (1) | MA25515A1 (fr) |
NO (1) | NO317981B1 (fr) |
NZ (1) | NZ506807A (fr) |
PT (1) | PT1192134E (fr) |
TN (1) | TNSN99035A1 (fr) |
TW (1) | TWI249526B (fr) |
WO (1) | WO1999046245A2 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6713627B2 (en) * | 1998-03-13 | 2004-03-30 | Aventis Pharmaceuticals Inc. | Processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol |
DE19934432A1 (de) | 1999-07-22 | 2001-02-01 | Merck Patent Gmbh | Indolderivate |
EP1370244A1 (fr) * | 2001-03-12 | 2003-12-17 | Novo Nordisk A/S | Nouveaux comprimes et gelules et procede de preparation correspondant |
DE102004010132A1 (de) * | 2004-02-27 | 2005-09-15 | Merck Patent Gmbh | Piperidinderivate |
EP2100609A4 (fr) * | 2006-12-07 | 2010-01-06 | Daiichi Sankyo Co Ltd | Préparation médicale sous forme solide contenant un mannitol ou un lactose |
US8964338B2 (en) | 2012-01-11 | 2015-02-24 | Emerson Climate Technologies, Inc. | System and method for compressor motor protection |
US9638436B2 (en) | 2013-03-15 | 2017-05-02 | Emerson Electric Co. | HVAC system remote monitoring and diagnosis |
CN112358398A (zh) * | 2020-11-19 | 2021-02-12 | 山东新华制药股份有限公司 | D-(+)-二对甲苯甲酰酒石酸的回收制备方法 |
CN116082705B (zh) * | 2022-12-05 | 2023-09-12 | 苏州易昇光学材料股份有限公司 | 一种抗黄变自修复凝胶 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4260623A (en) * | 1979-11-26 | 1981-04-07 | Warner-Lambert Company | Hexahydro-1-arylspiro(3H-oxazolo(3,4-A)pyridine-3,4'-piperidene) antidepressants, pharmaceutical compositions thereof and method of use thereof |
ZA864772B (en) * | 1985-07-02 | 1987-02-25 | Merrell Dow Pharma | Novel chemical compounds |
US5169096A (en) * | 1985-07-02 | 1992-12-08 | Merrell Dow Pharmaceuticals Inc. | N-aralkyl-piperidine-methanol derivatives |
AU652759B2 (en) * | 1990-06-01 | 1994-09-08 | Aventisub Ii Inc. | (+)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)- 4-piperidinemethanol |
DE69123052T2 (de) * | 1990-06-07 | 1997-03-06 | Merrell Pharma Inc | Derivate des 1-piperidinyl-alkanoylarylsulfonamids |
US5477029A (en) * | 1994-01-28 | 1995-12-19 | Skutt Ceramic Products, Inc. | Kiln with hinged control panel |
US5618824A (en) * | 1994-03-09 | 1997-04-08 | Merrell Pharmaceuticals Inc. | Treatment of obsessive-compulsive disorders with 5-HT2 antagonists |
EP0796619A1 (fr) * | 1996-03-21 | 1997-09-24 | Merrell Pharmaceuticals Inc. | Utilisation de (+)-alpha-(2,3-diméthoxyphényle)-1-(2-(4-fluorophényle)éthyle)-4-pipéridineméthanol pour le traitement des troubles dépressifs et bipolaires |
-
1999
- 1999-03-09 TW TW088103619A patent/TWI249526B/zh not_active IP Right Cessation
- 1999-03-10 DZ DZ990043A patent/DZ2742A1/fr active
- 1999-03-10 EG EG23399A patent/EG24052A/xx active
- 1999-03-10 MA MA25491A patent/MA25515A1/fr unknown
- 1999-03-11 CN CNB998060224A patent/CN100436415C/zh not_active Expired - Fee Related
- 1999-03-11 JP JP2000535626A patent/JP4511723B2/ja not_active Expired - Fee Related
- 1999-03-11 WO PCT/US1999/005332 patent/WO1999046245A2/fr active IP Right Grant
- 1999-03-11 BR BR9909260-3A patent/BR9909260A/pt not_active Application Discontinuation
- 1999-03-11 KR KR1020057024567A patent/KR100591643B1/ko not_active IP Right Cessation
- 1999-03-11 ES ES99911318T patent/ES2294838T3/es not_active Expired - Lifetime
- 1999-03-11 NZ NZ506807A patent/NZ506807A/xx unknown
- 1999-03-11 PT PT99911318T patent/PT1192134E/pt unknown
- 1999-03-11 TN TNTNSN99035A patent/TNSN99035A1/fr unknown
- 1999-03-11 AR ARP990101039A patent/AR015540A1/es unknown
- 1999-03-11 AU AU29988/99A patent/AU755436B2/en not_active Ceased
- 1999-03-11 CA CA002322501A patent/CA2322501C/fr not_active Expired - Fee Related
- 1999-03-11 DE DE69937162T patent/DE69937162T2/de not_active Expired - Lifetime
- 1999-03-11 KR KR1020057024569A patent/KR100586327B1/ko not_active IP Right Cessation
- 1999-03-11 KR KR1020057024570A patent/KR100586328B1/ko not_active IP Right Cessation
- 1999-03-11 EP EP06016486A patent/EP1734037A3/fr not_active Ceased
- 1999-03-11 KR KR1020007010103A patent/KR100591642B1/ko not_active IP Right Cessation
- 1999-03-11 KR KR1020057024573A patent/KR100591641B1/ko not_active IP Right Cessation
- 1999-03-11 HU HU0400889A patent/HUP0400889A3/hu unknown
- 1999-03-11 DK DK99911318T patent/DK1192134T3/da active
- 1999-03-11 AT AT99911318T patent/ATE373639T1/de not_active IP Right Cessation
- 1999-03-11 KR KR1020057024568A patent/KR100591640B1/ko not_active IP Right Cessation
- 1999-03-11 KR KR1020057024572A patent/KR100591997B1/ko not_active IP Right Cessation
- 1999-03-11 EP EP06016487A patent/EP1736469A3/fr not_active Withdrawn
- 1999-03-11 IL IL13830799A patent/IL138307A0/xx active IP Right Grant
- 1999-03-11 EP EP99911318A patent/EP1192134B1/fr not_active Expired - Lifetime
-
2000
- 2000-09-06 IL IL138307A patent/IL138307A/en not_active IP Right Cessation
- 2000-09-12 NO NO20004545A patent/NO317981B1/no not_active IP Right Cessation
-
2002
- 2002-05-08 HK HK02103493.4A patent/HK1042484B/zh not_active IP Right Cessation
-
2006
- 2006-05-29 IL IL175983A patent/IL175983A0/en unknown
-
2007
- 2007-12-19 CY CY20071101617T patent/CY1107104T1/el unknown
-
2009
- 2009-12-28 JP JP2009296809A patent/JP2010143925A/ja not_active Abandoned
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