TNSN88123A1 - Procede de preparation de derives de thieno-imidazole substitue utilisables comme inhibiteurs de la secretion d'acidite gastrique - Google Patents
Procede de preparation de derives de thieno-imidazole substitue utilisables comme inhibiteurs de la secretion d'acidite gastriqueInfo
- Publication number
- TNSN88123A1 TNSN88123A1 TNTNSN88123A TNSN88123A TNSN88123A1 TN SN88123 A1 TNSN88123 A1 TN SN88123A1 TN TNSN88123 A TNTNSN88123 A TN TNSN88123A TN SN88123 A TNSN88123 A TN SN88123A TN SN88123 A1 TNSN88123 A1 TN SN88123A1
- Authority
- TN
- Tunisia
- Prior art keywords
- preparation
- secretion
- imidazole derivatives
- inhibitors
- gastric acidity
- Prior art date
Links
- JCZAVVUIFWZMQI-UHFFFAOYSA-N 1h-thieno[2,3-d]imidazole Chemical class N1C=NC2=C1C=CS2 JCZAVVUIFWZMQI-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 230000002496 gastric effect Effects 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 230000028327 secretion Effects 0.000 title abstract 2
- 230000027119 gastric acid secretion Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nutrition Science (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDE DE PREPAR,ATION DE DERIVES DE THIENO-IMIDAZOLE SUBSTITUES UTILISABLES COMME INHIBITEURS DE LA SECRETION D'ACIDITE GASTRIQUE. L'INVENTION CONCERNE UN PROCEDE DE PREPARATION DE DERIVES DE THIENO-IMIDAZOLE DE FORMULE (I) DANS LAQUELLE A REPRESENTE a), b) OU c), T REPRESENTE -S-, -SO- OU -SO2- ; R7 REPRESENTE UN RADICAL ARYLOXY OU ARALKYLOXY SUBSTITUE, ET R1,R2,R3,R4,R5,R6 ET R8 ONT LES SIGNIFICATIONS DONNEES DANS LA DESCRIPTION, QUI SONT UTILISABLES EN TANT QUE MEDICAMENTS, NOTAMMENT POUR INHIBER LA SECRETION D'ACIDE GASTRIQUE
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3738520 | 1987-11-13 | ||
DE3819084 | 1988-06-04 | ||
DE3828158 | 1988-08-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
TNSN88123A1 true TNSN88123A1 (fr) | 1990-07-10 |
Family
ID=27196772
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TNTNSN88123A TNSN88123A1 (fr) | 1987-11-13 | 1988-11-14 | Procede de preparation de derives de thieno-imidazole substitue utilisables comme inhibiteurs de la secretion d'acidite gastrique |
Country Status (20)
Country | Link |
---|---|
US (1) | US5114955A (fr) |
EP (1) | EP0321385B1 (fr) |
JP (1) | JPH01160984A (fr) |
KR (1) | KR890008146A (fr) |
CN (1) | CN1029314C (fr) |
AT (1) | ATE110078T1 (fr) |
AU (1) | AU607279B2 (fr) |
DE (1) | DE3851133D1 (fr) |
DK (1) | DK166415B1 (fr) |
ES (1) | ES2060672T3 (fr) |
FI (1) | FI90426C (fr) |
HU (1) | HU202238B (fr) |
IE (1) | IE64073B1 (fr) |
IL (1) | IL88349A (fr) |
MA (1) | MA21434A1 (fr) |
NO (1) | NO167981C (fr) |
NZ (1) | NZ226928A (fr) |
PH (1) | PH26365A (fr) |
PT (1) | PT88976B (fr) |
TN (1) | TNSN88123A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6852739B1 (en) | 1999-02-26 | 2005-02-08 | Nitromed Inc. | Methods using proton pump inhibitors and nitric oxide donors |
EP1534278A4 (fr) * | 2002-08-01 | 2006-09-06 | Nitromed Inc | Inhibiteurs nitroses de la pompe a protons, compositions et procedes d'utilisation |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1234058A (fr) * | 1968-10-21 | 1971-06-03 | ||
GB8417171D0 (en) * | 1984-07-05 | 1984-08-08 | Beecham Group Plc | Compounds |
FI861772A (fi) * | 1985-05-07 | 1986-11-08 | Chemie Linz Ag | Nya tieno(2,3-d)imidazolderivat och foerfarande for deras framstaellning. |
ES2032394T3 (es) * | 1986-02-20 | 1993-02-16 | Hoechst Aktiengesellschaft | Procedimiento para preparar derivados de tienoimidazol sustituidos. |
WO1987005296A1 (fr) * | 1986-03-07 | 1987-09-11 | Pfizer Inc. | 2-[(2-pyridyl)methylsulfinyl]thienoimidazoles et composes apparentes utilises en tant qu'agents de traitement ou de prevention des ulceres |
AU622866B2 (en) * | 1987-07-21 | 1992-04-30 | Hoechst Aktiengesellschaft | Substituted thienoimidazole derivatives, processes for their preparation, pharmaceutical formulations containing them and their use as gastric acid secretion inhibitors |
-
1988
- 1988-11-04 DE DE3851133T patent/DE3851133D1/de not_active Expired - Fee Related
- 1988-11-04 EP EP88710043A patent/EP0321385B1/fr not_active Expired - Lifetime
- 1988-11-04 AT AT88710043T patent/ATE110078T1/de not_active IP Right Cessation
- 1988-11-04 ES ES88710043T patent/ES2060672T3/es not_active Expired - Lifetime
- 1988-11-10 FI FI885172A patent/FI90426C/fi not_active IP Right Cessation
- 1988-11-10 PT PT88976A patent/PT88976B/pt not_active IP Right Cessation
- 1988-11-10 IL IL88349A patent/IL88349A/xx not_active IP Right Cessation
- 1988-11-10 US US07/269,285 patent/US5114955A/en not_active Expired - Fee Related
- 1988-11-11 MA MA21676A patent/MA21434A1/fr unknown
- 1988-11-11 DK DK631188A patent/DK166415B1/da not_active IP Right Cessation
- 1988-11-11 NZ NZ226928A patent/NZ226928A/xx unknown
- 1988-11-11 JP JP63284094A patent/JPH01160984A/ja active Pending
- 1988-11-11 PH PH37806A patent/PH26365A/en unknown
- 1988-11-11 IE IE339288A patent/IE64073B1/en not_active IP Right Cessation
- 1988-11-11 AU AU25034/88A patent/AU607279B2/en not_active Ceased
- 1988-11-11 HU HU885792A patent/HU202238B/hu not_active IP Right Cessation
- 1988-11-11 NO NO885040A patent/NO167981C/no unknown
- 1988-11-11 KR KR1019880014810A patent/KR890008146A/ko not_active Application Discontinuation
- 1988-11-12 CN CN88107814A patent/CN1029314C/zh not_active Expired - Fee Related
- 1988-11-14 TN TNTNSN88123A patent/TNSN88123A1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
EP0321385A2 (fr) | 1989-06-21 |
PT88976B (pt) | 1993-01-29 |
FI885172A (fi) | 1989-05-14 |
JPH01160984A (ja) | 1989-06-23 |
NO167981C (no) | 1992-01-02 |
EP0321385A3 (en) | 1990-06-06 |
AU607279B2 (en) | 1991-02-28 |
NO167981B (no) | 1991-09-23 |
HU202238B (en) | 1991-02-28 |
PT88976A (pt) | 1988-12-01 |
HUT50828A (en) | 1990-03-28 |
DK631188D0 (da) | 1988-11-11 |
FI90426C (fi) | 1994-02-10 |
ES2060672T3 (es) | 1994-12-01 |
FI885172A0 (fi) | 1988-11-10 |
EP0321385B1 (fr) | 1994-08-17 |
KR890008146A (ko) | 1989-07-10 |
AU2503488A (en) | 1989-05-18 |
DK631188A (da) | 1989-05-14 |
CN1029314C (zh) | 1995-07-12 |
US5114955A (en) | 1992-05-19 |
MA21434A1 (fr) | 1989-07-01 |
NO885040L (no) | 1989-05-16 |
IL88349A (en) | 1993-03-15 |
IL88349A0 (en) | 1989-06-30 |
ATE110078T1 (de) | 1994-09-15 |
NZ226928A (en) | 1991-08-27 |
DE3851133D1 (de) | 1994-09-22 |
FI90426B (fi) | 1993-10-29 |
NO885040D0 (no) | 1988-11-11 |
IE883392L (en) | 1989-05-13 |
DK166415B1 (da) | 1993-05-17 |
CN1033052A (zh) | 1989-05-24 |
IE64073B1 (en) | 1995-07-12 |
PH26365A (en) | 1992-06-01 |
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