TNSN88123A1 - Procede de preparation de derives de thieno-imidazole substitue utilisables comme inhibiteurs de la secretion d'acidite gastrique - Google Patents

Procede de preparation de derives de thieno-imidazole substitue utilisables comme inhibiteurs de la secretion d'acidite gastrique

Info

Publication number
TNSN88123A1
TNSN88123A1 TNTNSN88123A TNSN88123A TNSN88123A1 TN SN88123 A1 TNSN88123 A1 TN SN88123A1 TN TNSN88123 A TNTNSN88123 A TN TNSN88123A TN SN88123 A TNSN88123 A TN SN88123A TN SN88123 A1 TNSN88123 A1 TN SN88123A1
Authority
TN
Tunisia
Prior art keywords
preparation
secretion
imidazole derivatives
inhibitors
gastric acidity
Prior art date
Application number
TNTNSN88123A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of TNSN88123A1 publication Critical patent/TNSN88123A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDE DE PREPAR,ATION DE DERIVES DE THIENO-IMIDAZOLE SUBSTITUES UTILISABLES COMME INHIBITEURS DE LA SECRETION D'ACIDITE GASTRIQUE. L'INVENTION CONCERNE UN PROCEDE DE PREPARATION DE DERIVES DE THIENO-IMIDAZOLE DE FORMULE (I) DANS LAQUELLE A REPRESENTE a), b) OU c), T REPRESENTE -S-, -SO- OU -SO2- ; R7 REPRESENTE UN RADICAL ARYLOXY OU ARALKYLOXY SUBSTITUE, ET R1,R2,R3,R4,R5,R6 ET R8 ONT LES SIGNIFICATIONS DONNEES DANS LA DESCRIPTION, QUI SONT UTILISABLES EN TANT QUE MEDICAMENTS, NOTAMMENT POUR INHIBER LA SECRETION D'ACIDE GASTRIQUE
TNTNSN88123A 1987-11-13 1988-11-14 Procede de preparation de derives de thieno-imidazole substitue utilisables comme inhibiteurs de la secretion d'acidite gastrique TNSN88123A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE3738520 1987-11-13
DE3819084 1988-06-04
DE3828158 1988-08-19

Publications (1)

Publication Number Publication Date
TNSN88123A1 true TNSN88123A1 (fr) 1990-07-10

Family

ID=27196772

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN88123A TNSN88123A1 (fr) 1987-11-13 1988-11-14 Procede de preparation de derives de thieno-imidazole substitue utilisables comme inhibiteurs de la secretion d'acidite gastrique

Country Status (20)

Country Link
US (1) US5114955A (fr)
EP (1) EP0321385B1 (fr)
JP (1) JPH01160984A (fr)
KR (1) KR890008146A (fr)
CN (1) CN1029314C (fr)
AT (1) ATE110078T1 (fr)
AU (1) AU607279B2 (fr)
DE (1) DE3851133D1 (fr)
DK (1) DK166415B1 (fr)
ES (1) ES2060672T3 (fr)
FI (1) FI90426C (fr)
HU (1) HU202238B (fr)
IE (1) IE64073B1 (fr)
IL (1) IL88349A (fr)
MA (1) MA21434A1 (fr)
NO (1) NO167981C (fr)
NZ (1) NZ226928A (fr)
PH (1) PH26365A (fr)
PT (1) PT88976B (fr)
TN (1) TNSN88123A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
EP1534278A4 (fr) * 2002-08-01 2006-09-06 Nitromed Inc Inhibiteurs nitroses de la pompe a protons, compositions et procedes d'utilisation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234058A (fr) * 1968-10-21 1971-06-03
GB8417171D0 (en) * 1984-07-05 1984-08-08 Beecham Group Plc Compounds
FI861772A (fi) * 1985-05-07 1986-11-08 Chemie Linz Ag Nya tieno(2,3-d)imidazolderivat och foerfarande for deras framstaellning.
ES2032394T3 (es) * 1986-02-20 1993-02-16 Hoechst Aktiengesellschaft Procedimiento para preparar derivados de tienoimidazol sustituidos.
WO1987005296A1 (fr) * 1986-03-07 1987-09-11 Pfizer Inc. 2-[(2-pyridyl)methylsulfinyl]thienoimidazoles et composes apparentes utilises en tant qu'agents de traitement ou de prevention des ulceres
AU622866B2 (en) * 1987-07-21 1992-04-30 Hoechst Aktiengesellschaft Substituted thienoimidazole derivatives, processes for their preparation, pharmaceutical formulations containing them and their use as gastric acid secretion inhibitors

Also Published As

Publication number Publication date
EP0321385A2 (fr) 1989-06-21
PT88976B (pt) 1993-01-29
FI885172A (fi) 1989-05-14
JPH01160984A (ja) 1989-06-23
NO167981C (no) 1992-01-02
EP0321385A3 (en) 1990-06-06
AU607279B2 (en) 1991-02-28
NO167981B (no) 1991-09-23
HU202238B (en) 1991-02-28
PT88976A (pt) 1988-12-01
HUT50828A (en) 1990-03-28
DK631188D0 (da) 1988-11-11
FI90426C (fi) 1994-02-10
ES2060672T3 (es) 1994-12-01
FI885172A0 (fi) 1988-11-10
EP0321385B1 (fr) 1994-08-17
KR890008146A (ko) 1989-07-10
AU2503488A (en) 1989-05-18
DK631188A (da) 1989-05-14
CN1029314C (zh) 1995-07-12
US5114955A (en) 1992-05-19
MA21434A1 (fr) 1989-07-01
NO885040L (no) 1989-05-16
IL88349A (en) 1993-03-15
IL88349A0 (en) 1989-06-30
ATE110078T1 (de) 1994-09-15
NZ226928A (en) 1991-08-27
DE3851133D1 (de) 1994-09-22
FI90426B (fi) 1993-10-29
NO885040D0 (no) 1988-11-11
IE883392L (en) 1989-05-13
DK166415B1 (da) 1993-05-17
CN1033052A (zh) 1989-05-24
IE64073B1 (en) 1995-07-12
PH26365A (en) 1992-06-01

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