TNSN08537A1 - Precurseurs de medicaments du type peneme - Google Patents

Precurseurs de medicaments du type peneme

Info

Publication number
TNSN08537A1
TNSN08537A1 TNP2008000537A TNSN08537A TNSN08537A1 TN SN08537 A1 TNSN08537 A1 TN SN08537A1 TN P2008000537 A TNP2008000537 A TN P2008000537A TN SN08537 A TNSN08537 A TN SN08537A TN SN08537 A1 TNSN08537 A1 TN SN08537A1
Authority
TN
Tunisia
Prior art keywords
type
peneme
drug precursors
precursors
drug
Prior art date
Application number
TNP2008000537A
Other languages
English (en)
Inventor
Dale Gordon Mcleod
Katherine Elizabeth Brighty
John Paul O'donnell
Anthony Marfat
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of TNSN08537A1 publication Critical patent/TNSN08537A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/887—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with a hetero atom or a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Des précurseurs, doués de biodisponibilité orale, de médicaments du type sulopénème, par exemple (I) et leurs produits de solvatation et hydrates, leur préparation, leur formulation, et l'utilisation pour traiter et prévenir une infection chez des mammifères tels que les êtres humains. Cet abrégé ne limite pas l'invention.
TNP2008000537A 2006-06-28 2008-12-26 Precurseurs de medicaments du type peneme TNSN08537A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80600006P 2006-06-28 2006-06-28
US91158707P 2007-04-13 2007-04-13
PCT/IB2007/001843 WO2008001212A2 (fr) 2006-06-28 2007-06-18 Prodrogues de pénem

Publications (1)

Publication Number Publication Date
TNSN08537A1 true TNSN08537A1 (fr) 2010-04-14

Family

ID=38463109

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2008000537A TNSN08537A1 (fr) 2006-06-28 2008-12-26 Precurseurs de medicaments du type peneme

Country Status (29)

Country Link
US (2) US7795243B2 (fr)
EP (1) EP2044085B1 (fr)
JP (2) JP4397435B2 (fr)
KR (1) KR101060448B1 (fr)
AP (1) AP2008004705A0 (fr)
AR (1) AR061646A1 (fr)
AT (1) ATE493419T1 (fr)
AU (1) AU2007263519B2 (fr)
BR (1) BRPI0712740A2 (fr)
CA (1) CA2655485C (fr)
CL (1) CL2007001910A1 (fr)
CR (1) CR10467A (fr)
DE (1) DE602007011622D1 (fr)
DK (1) DK2044085T3 (fr)
EA (1) EA200870584A1 (fr)
EC (1) ECSP088947A (fr)
GT (1) GT200700050A (fr)
HK (1) HK1134928A1 (fr)
IL (1) IL195383A0 (fr)
MA (1) MA30568B1 (fr)
MX (1) MX2009000116A (fr)
NL (1) NL2000715C2 (fr)
NO (1) NO20090392L (fr)
PE (1) PE20080940A1 (fr)
SV (1) SV2008003139A (fr)
TN (1) TNSN08537A1 (fr)
TW (1) TW200816999A (fr)
UY (1) UY30439A1 (fr)
WO (1) WO2008001212A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20080940A1 (es) * 2006-06-28 2008-07-09 Pfizer Prod Inc Profarmacos de penem
US20080125408A1 (en) * 2006-11-14 2008-05-29 Pfizer Inc Penem prodrug
WO2009108704A1 (fr) * 2008-02-25 2009-09-03 Semafore Pharmaceuticals, Inc. Combinaison de promédicaments inhibiteurs de pi-3 kinase o-alkylés
KR100916052B1 (ko) 2009-02-24 2009-09-08 코오롱건설주식회사 진공이송 쓰레기 수거시스템의 쓰레기 배출밸브
CA2768877A1 (fr) * 2009-08-10 2011-02-17 Bellus Health Inc. Procedes, composes, et compositions pour administrer de l'acide 1,3-propane disulfonique
US11554112B2 (en) * 2018-06-07 2023-01-17 Herum Therapeutics International Limited Combinations of β-lactam compounds and probenecid and uses thereof
EA202192193A1 (ru) 2019-02-13 2021-11-09 Итерум Терапьютикс Интернэшнл Лимитед Комбинации бета-лактамных соединений и пробенецида и их применения

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619924A (en) * 1984-05-18 1986-10-28 Pfizer Inc. 2-alkylthiopenem derivatives
US4870170A (en) * 1985-10-17 1989-09-26 Pfizer Inc. Process for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics
WO1988008845A1 (fr) * 1987-05-11 1988-11-17 Pfizer Inc. Acides diastereomeres 5r,6s-6-(1r-hydroxyethyle)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxyliques
GB8713515D0 (en) 1987-06-10 1987-07-15 Erba Farmitalia Methoxymethyl compounds
US4874877A (en) * 1988-04-19 1989-10-17 Pfizer Inc. Process for optically active 3-(methane-sulfonyloxy)thiolane and analogs
US5703068A (en) 1990-08-20 1997-12-30 Suntory Limited Penem compounds
EP0544905B1 (fr) 1990-08-20 1998-10-14 Suntory Limited Composes antibacteriens de penem
WO2004067532A1 (fr) 2003-01-31 2004-08-12 Meiji Seika Kaisha, Ltd. Nouveaux dérivés de carbapenem
PE20080940A1 (es) * 2006-06-28 2008-07-09 Pfizer Prod Inc Profarmacos de penem
WO2008008845A2 (fr) * 2006-07-11 2008-01-17 Microchips, Inc. Dispositif multi-réservoirs à pompe pour dialyse, biodétection ou administration de substances
US20080125408A1 (en) * 2006-11-14 2008-05-29 Pfizer Inc Penem prodrug

Also Published As

Publication number Publication date
GT200700050A (es) 2008-02-01
DE602007011622D1 (en) 2011-02-10
CA2655485A1 (fr) 2008-01-03
EP2044085A2 (fr) 2009-04-08
US7795243B2 (en) 2010-09-14
NL2000715A1 (nl) 2008-01-02
JP2009542616A (ja) 2009-12-03
IL195383A0 (en) 2009-08-03
JP5152527B2 (ja) 2013-02-27
AU2007263519A1 (en) 2008-01-03
WO2008001212A3 (fr) 2008-03-20
MX2009000116A (es) 2009-01-23
AP2008004705A0 (en) 2008-12-31
SV2008003139A (es) 2010-01-12
ATE493419T1 (de) 2011-01-15
HK1134928A1 (en) 2010-05-20
EP2044085B1 (fr) 2010-12-29
KR20090015147A (ko) 2009-02-11
CA2655485C (fr) 2011-08-02
KR101060448B1 (ko) 2011-08-29
ECSP088947A (es) 2009-01-30
NO20090392L (no) 2009-01-27
BRPI0712740A2 (pt) 2012-06-05
MA30568B1 (fr) 2009-07-01
JP2010013468A (ja) 2010-01-21
AR061646A1 (es) 2008-09-10
DK2044085T3 (da) 2011-03-07
CL2007001910A1 (es) 2008-01-11
US20080009474A1 (en) 2008-01-10
UY30439A1 (es) 2008-01-31
AU2007263519B2 (en) 2011-05-19
WO2008001212A2 (fr) 2008-01-03
TW200816999A (en) 2008-04-16
PE20080940A1 (es) 2008-07-09
US20090042853A1 (en) 2009-02-12
EA200870584A1 (ru) 2009-06-30
JP4397435B2 (ja) 2010-01-13
NL2000715C2 (nl) 2008-03-11
CR10467A (es) 2009-01-19
US7795244B2 (en) 2010-09-14

Similar Documents

Publication Publication Date Title
TNSN08537A1 (fr) Precurseurs de medicaments du type peneme
BR0214343A (pt) Inibidores de 11 - beta - hidroxi esteróide desidrogenase tipo 1
CR20220675A (es) Análogos de nucleósido de 1´- ciano y usos de los mismos
SE0102315D0 (sv) Compounds
MXPA04002167A (es) Inhibidores de la 17 beta-hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades androgeno-dependientes.
DE69920757D1 (de) Immunsuppressive wirkungen von pteridinderivaten
HK1085667A1 (en) Non-nucleoside reverse transcriptase inhibitors
EA201270738A1 (ru) Модуляторы фармакокинетических свойств лекарственных средств
UA95715C2 (ru) Фосфадиазиновые производные, фармацевтическая композиция и их применение
MA29213B1 (fr) Quinolones a substitution macrolones - amino
WO2007128086A3 (fr) Nouvel inhibiteur de la réplication virale
ES2186550A1 (es) Nuevos derivados de oxazolidinonas como antibacterianos.
CR20230100A (es) Compuestos fosfolípidos y usos de los mismos
BR0315139A (pt) Agentes antibacterianos de tetraidroquinolina tricìclica
DE60001586D1 (de) Diphenyl-piperidin derivate
ATE360428T1 (de) Analgetisches arzneimittel
IL157065A0 (en) 2h-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof
EP1626731A4 (fr) Compositions pharmaceutiques anti-inflammatoires permettant de reduire une inflammation et traitement ou prevention de la toxicite gastrique
AU4568400A (en) Sphingomyelinase inhibitor
MA32128B1 (fr) Association entre un sel de bis-thiazolium ou l'un de ses precurseurs et l'artémisinine ou l'un de ses derives pour le traitement du paludisme severe
BRPI0713278A2 (pt) agente profilÁtico ou terapÊutico para doenÇa viral
PE20030236A1 (es) Derivados de bencimidazol 1-aril-2-n,s- u o-sustituidos, obtencion de medicamentos y preparados farmaceuticos que contienen estos derivados
NO20020914L (no) Alkoksy-substituerte benzimidazolforbindelser, preparater inneholdende slike samt anvendelser derav
MXPA02012232A (es) Preparacion antipiretica concentrada de xilitol.
ATE277622T1 (de) Arzneimittel enthaltend xenogene oligo- oder/und polyribonukleotide