MA30568B1 - Precurseurs de medicaments du type peneme - Google Patents
Precurseurs de medicaments du type penemeInfo
- Publication number
- MA30568B1 MA30568B1 MA31512A MA31512A MA30568B1 MA 30568 B1 MA30568 B1 MA 30568B1 MA 31512 A MA31512 A MA 31512A MA 31512 A MA31512 A MA 31512A MA 30568 B1 MA30568 B1 MA 30568B1
- Authority
- MA
- Morocco
- Prior art keywords
- type
- peneme
- precursors
- abstract
- drug precursors
- Prior art date
Links
- 239000002243 precursor Substances 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- HHXMXAQDOUCLDN-RXMQYKEDSA-N penem Chemical compound S1C=CN2C(=O)C[C@H]21 HHXMXAQDOUCLDN-RXMQYKEDSA-N 0.000 title abstract 2
- FLSUCZWOEMTFAQ-PRBGKLEPSA-N (5r,6s)-6-[(1r)-1-hydroxyethyl]-7-oxo-3-[(1r,3s)-1-oxothiolan-3-yl]sulfanyl-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid Chemical compound S([C@@H]1[C@H](C(N1C=1C(O)=O)=O)[C@H](O)C)C=1S[C@H]1CC[S@@](=O)C1 FLSUCZWOEMTFAQ-PRBGKLEPSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 229950000153 sulopenem Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/887—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with a hetero atom or a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
DEPOSANT Société dite : PFIZER PRODUCT INC. REVENDICATION DE PRIORITES 28/06/2006 US 60/806000 13/04/2007 US 60/911587 Voir en annexe le titre de l'invention et le texte de l'abrégé Précurseurs de médicaments du type pénème Des précurseurs, doués de biodisponibilité orale, de médicaments du type sulopénème, par exemple (I) et leurs produits de solvatation et hydrates, leur préparation, leur formulation, et l'utilisation pour traiter et prévenir une infection chez des mammifères tels que les êtres humains. Cet abrégé ne limite pas l'invention.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80600006P | 2006-06-28 | 2006-06-28 | |
| US91158707P | 2007-04-13 | 2007-04-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA30568B1 true MA30568B1 (fr) | 2009-07-01 |
Family
ID=38463109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA31512A MA30568B1 (fr) | 2006-06-28 | 2008-12-26 | Precurseurs de medicaments du type peneme |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US7795243B2 (fr) |
| EP (1) | EP2044085B1 (fr) |
| JP (2) | JP4397435B2 (fr) |
| KR (1) | KR101060448B1 (fr) |
| AP (1) | AP2008004705A0 (fr) |
| AR (1) | AR061646A1 (fr) |
| AT (1) | ATE493419T1 (fr) |
| AU (1) | AU2007263519B2 (fr) |
| BR (1) | BRPI0712740A2 (fr) |
| CA (1) | CA2655485C (fr) |
| CL (1) | CL2007001910A1 (fr) |
| CR (1) | CR10467A (fr) |
| DE (1) | DE602007011622D1 (fr) |
| DK (1) | DK2044085T3 (fr) |
| EA (1) | EA200870584A1 (fr) |
| EC (1) | ECSP088947A (fr) |
| GT (1) | GT200700050A (fr) |
| HK (1) | HK1134928A1 (fr) |
| IL (1) | IL195383A0 (fr) |
| MA (1) | MA30568B1 (fr) |
| MX (1) | MX2009000116A (fr) |
| NL (1) | NL2000715C2 (fr) |
| NO (1) | NO20090392L (fr) |
| PE (1) | PE20080940A1 (fr) |
| SV (1) | SV2008003139A (fr) |
| TN (1) | TNSN08537A1 (fr) |
| TW (1) | TW200816999A (fr) |
| UY (1) | UY30439A1 (fr) |
| WO (1) | WO2008001212A2 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20080940A1 (es) * | 2006-06-28 | 2008-07-09 | Pfizer Prod Inc | Profarmacos de penem |
| US20080125408A1 (en) * | 2006-11-14 | 2008-05-29 | Pfizer Inc | Penem prodrug |
| WO2009108704A1 (fr) * | 2008-02-25 | 2009-09-03 | Semafore Pharmaceuticals, Inc. | Combinaison de promédicaments inhibiteurs de pi-3 kinase o-alkylés |
| KR100916052B1 (ko) | 2009-02-24 | 2009-09-08 | 코오롱건설주식회사 | 진공이송 쓰레기 수거시스템의 쓰레기 배출밸브 |
| NZ598085A (en) * | 2009-08-10 | 2014-02-28 | Bhi Ltd Partnership | Methods, compounds, and compositions for delivering 1,3-propanedisulfonic acid |
| US11554112B2 (en) * | 2018-06-07 | 2023-01-17 | Herum Therapeutics International Limited | Combinations of β-lactam compounds and probenecid and uses thereof |
| MX2021009755A (es) * | 2019-02-13 | 2021-11-17 | Iterum Therapeutics International Ltd | Combinaciones de compuestos beta-lactámicos y probenecid, y usos de los mismos. |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4619924A (en) * | 1984-05-18 | 1986-10-28 | Pfizer Inc. | 2-alkylthiopenem derivatives |
| US4870170A (en) * | 1985-10-17 | 1989-09-26 | Pfizer Inc. | Process for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics |
| US5013729A (en) | 1987-05-11 | 1991-05-07 | Pfizer Inc. | Diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids |
| GB8713515D0 (en) | 1987-06-10 | 1987-07-15 | Erba Farmitalia | Methoxymethyl compounds |
| US4874877A (en) * | 1988-04-19 | 1989-10-17 | Pfizer Inc. | Process for optically active 3-(methane-sulfonyloxy)thiolane and analogs |
| US5703068A (en) | 1990-08-20 | 1997-12-30 | Suntory Limited | Penem compounds |
| CA2089369C (fr) | 1990-08-20 | 2002-10-08 | Hiromitsu Iwata | Composes de penem a proprietes antibacteriennes |
| WO2004067532A1 (fr) | 2003-01-31 | 2004-08-12 | Meiji Seika Kaisha, Ltd. | Nouveaux dérivés de carbapenem |
| PE20080940A1 (es) * | 2006-06-28 | 2008-07-09 | Pfizer Prod Inc | Profarmacos de penem |
| EP2043728A2 (fr) * | 2006-07-11 | 2009-04-08 | Microchips, Inc. | Dispositif multi-réservoirs à pompe pour dialyse, biodétection ou administration de substances |
| US20080125408A1 (en) * | 2006-11-14 | 2008-05-29 | Pfizer Inc | Penem prodrug |
-
2007
- 2007-06-14 PE PE2007000755A patent/PE20080940A1/es not_active Application Discontinuation
- 2007-06-18 CA CA2655485A patent/CA2655485C/fr not_active Expired - Fee Related
- 2007-06-18 AT AT07734929T patent/ATE493419T1/de not_active IP Right Cessation
- 2007-06-18 JP JP2009517474A patent/JP4397435B2/ja not_active Expired - Fee Related
- 2007-06-18 DE DE602007011622T patent/DE602007011622D1/de active Active
- 2007-06-18 KR KR1020087031533A patent/KR101060448B1/ko not_active IP Right Cessation
- 2007-06-18 WO PCT/IB2007/001843 patent/WO2008001212A2/fr active Application Filing
- 2007-06-18 EA EA200870584A patent/EA200870584A1/ru unknown
- 2007-06-18 BR BRPI0712740-5A patent/BRPI0712740A2/pt not_active IP Right Cessation
- 2007-06-18 AU AU2007263519A patent/AU2007263519B2/en not_active Ceased
- 2007-06-18 MX MX2009000116A patent/MX2009000116A/es active IP Right Grant
- 2007-06-18 DK DK07734929.8T patent/DK2044085T3/da active
- 2007-06-18 EP EP07734929A patent/EP2044085B1/fr active Active
- 2007-06-18 AP AP2008004705A patent/AP2008004705A0/xx unknown
- 2007-06-19 NL NL2000715A patent/NL2000715C2/nl not_active IP Right Cessation
- 2007-06-25 GT GT200700050A patent/GT200700050A/es unknown
- 2007-06-26 UY UY30439A patent/UY30439A1/es not_active Application Discontinuation
- 2007-06-26 AR ARP070102825A patent/AR061646A1/es not_active Application Discontinuation
- 2007-06-27 TW TW096123288A patent/TW200816999A/zh unknown
- 2007-06-28 CL CL2007001910A patent/CL2007001910A1/es unknown
- 2007-06-28 US US11/769,849 patent/US7795243B2/en active Active
-
2008
- 2008-06-30 US US12/164,818 patent/US7795244B2/en active Active
- 2008-11-19 IL IL195383A patent/IL195383A0/en unknown
- 2008-11-27 CR CR10467A patent/CR10467A/es not_active Application Discontinuation
- 2008-12-08 EC EC2008008947A patent/ECSP088947A/es unknown
- 2008-12-23 SV SV2008003139A patent/SV2008003139A/es not_active Application Discontinuation
- 2008-12-26 MA MA31512A patent/MA30568B1/fr unknown
- 2008-12-26 TN TNP2008000537A patent/TNSN08537A1/fr unknown
-
2009
- 2009-01-27 NO NO20090392A patent/NO20090392L/no not_active Application Discontinuation
- 2009-09-04 JP JP2009204301A patent/JP5152527B2/ja active Active
- 2009-12-23 HK HK09112093.2A patent/HK1134928A1/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA30568B1 (fr) | Precurseurs de medicaments du type peneme | |
| MX2009010289A (es) | Composiciones para administracion nasal. | |
| HUP0204023A2 (hu) | Pirrolidinacetamidszármazék alkalmazása önmagában vagy kombinációban központi idegrendszeri zavarok kezelésére és ezeket tartalmazó gyógyszerkészítmények | |
| MA33218B1 (fr) | Applications therapeutiques de derives de quinazolinedione | |
| SG11201808167VA (en) | Prodrugs of cytotoxic active agents having enzymatically cleavable groups | |
| MY145074A (en) | Thiazolidin-4-one derivatives | |
| NZ588913A (en) | Liver cancer drug | |
| EE200200207A (et) | Kinoliiniderivaatide kasutamine vähivastase ravimi valmistamiseks, ühendite saamine ning neid sisaldavad farmatseutilised kompositsioonid | |
| NO20042596L (no) | Inbibitorer av 11-beta-hydroksy steroid dehydrogenase type 1 | |
| WO2009121063A3 (fr) | Modulateurs du récepteur de la chimiokine | |
| UA95715C2 (ru) | Фосфадиазиновые производные, фармацевтическая композиция и их применение | |
| MA29213B1 (fr) | Quinolones a substitution macrolones - amino | |
| TNSN08139A1 (fr) | Composes therapeutiques | |
| TW200800931A (en) | Novel piperazines as antimalarial agents | |
| MA33302B1 (fr) | 2, 4-diaminopyrimidines pour le traitement de maladies caracterisees par une proliferation cellulaire excessive ou anormale | |
| WO2008020306A3 (fr) | Dérivés d'isoindole | |
| ES2186550A1 (es) | Nuevos derivados de oxazolidinonas como antibacterianos. | |
| PH12021550878A1 (en) | Cyclodextrin-based formulation of a bcl-2 inhibitor | |
| FR3055801B1 (fr) | Derives esters de squalamine pour le traitement des infections | |
| BRPI0410623A (pt) | composto, processo para preparação de um composto, composição farmacêutica, e, utilização de um composto | |
| CO5251446A1 (es) | Mezcla de linezolid y otros agentes antibacterianos | |
| BR112022007998A2 (pt) | Novo composto e composição farmacêutica para prevenção ou tratamento de câncer que compreende os mesmos | |
| DE50204789D1 (de) | Neue 1-amidomethylcarbonyl-piperidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel | |
| HK1107699A1 (en) | Ritonavir analogous compound useful as retroviral protease inhibitor, preparation of the ritonavir analogous compound and pharmaceutical composition for the ritonavir analogous compound | |
| AU4568400A (en) | Sphingomyelinase inhibitor |