TN2018000341A1 - ANTl-COMPLEMENT FACTOR BB ANTIBODIES AND USES THEREOF. - Google Patents

ANTl-COMPLEMENT FACTOR BB ANTIBODIES AND USES THEREOF.

Info

Publication number
TN2018000341A1
TN2018000341A1 TNP/2018/000341A TN2018000341A TN2018000341A1 TN 2018000341 A1 TN2018000341 A1 TN 2018000341A1 TN 2018000341 A TN2018000341 A TN 2018000341A TN 2018000341 A1 TN2018000341 A1 TN 2018000341A1
Authority
TN
Tunisia
Prior art keywords
antibodies
complément
des
anticorps
complement factor
Prior art date
Application number
TNP/2018/000341A
Other languages
English (en)
Inventor
Tony Sangyoung Byun
Karen Sue Christopherson
Sandip Panicker
Graham Parry
Original Assignee
Bioverativ Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioverativ Usa Inc filed Critical Bioverativ Usa Inc
Publication of TN2018000341A1 publication Critical patent/TN2018000341A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TNP/2018/000341A 2016-04-04 2017-04-03 ANTl-COMPLEMENT FACTOR BB ANTIBODIES AND USES THEREOF. TN2018000341A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662317897P 2016-04-04 2016-04-04
PCT/US2017/025784 WO2017176651A1 (en) 2016-04-04 2017-04-03 Anti-complement factor bb antibodies and uses thereof

Publications (1)

Publication Number Publication Date
TN2018000341A1 true TN2018000341A1 (en) 2020-06-15

Family

ID=60000646

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP/2018/000341A TN2018000341A1 (en) 2016-04-04 2017-04-03 ANTl-COMPLEMENT FACTOR BB ANTIBODIES AND USES THEREOF.

Country Status (23)

Country Link
US (3) US10934347B2 (https=)
EP (1) EP3452510A4 (https=)
JP (4) JP6967528B2 (https=)
KR (2) KR20240096672A (https=)
CN (2) CN116790614A (https=)
AU (2) AU2017246794B2 (https=)
BR (1) BR112018070357A2 (https=)
CA (1) CA3019332A1 (https=)
CL (1) CL2018002810A1 (https=)
CO (1) CO2018010827A2 (https=)
CR (1) CR20180529A (https=)
DO (1) DOP2018000219A (https=)
EA (1) EA201892225A1 (https=)
EC (1) ECSP18082302A (https=)
IL (3) IL311675A (https=)
MA (1) MA44878A (https=)
MX (2) MX2018012176A (https=)
MY (1) MY194603A (https=)
PE (1) PE20190209A1 (https=)
PH (1) PH12018502137A1 (https=)
SG (1) SG11201808525UA (https=)
TN (1) TN2018000341A1 (https=)
WO (1) WO2017176651A1 (https=)

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TWI542597B (zh) 2010-07-28 2016-07-21 吉林尼克公司 產生依序多聚體化免疫球蛋白fc組合物之天然人類蛋白質片段之融合蛋白
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EP3452510A4 (en) 2016-04-04 2020-01-15 Bioverativ USA Inc. ANTI-COMPLEMENT FACTOR BB ANTIBODIES AND USES THEREOF
CN110022898B (zh) 2016-12-09 2023-07-04 格利克尼克股份有限公司 用多价Fc化合物治疗炎性疾病的方法
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KR20220042128A (ko) * 2019-06-27 2022-04-04 베르조 테라퓨틱스, 아이엔씨. 골수성 세포 염증성 표현형을 조절하기 위한 항-cd53 조성물 및 방법, 그리고 이의 용도
TWI851771B (zh) * 2019-07-17 2024-08-11 美商雙子治療子公司 因子h增強抗體及其用途
US20230050339A1 (en) * 2020-02-18 2023-02-16 Children's Hospital Medical Center Compositions and methods for treating liver disease
EP4139350A4 (en) 2020-04-20 2024-04-24 Genzyme Corporation Humanized anti-complement factor bb antibodies and uses thereof
CN116437913A (zh) 2020-09-23 2023-07-14 艾其林医药公司 用于治疗补体介导的病症的药物化合物

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Also Published As

Publication number Publication date
JP2026069789A (ja) 2026-04-24
IL262010A (en) 2018-10-31
IL295288B1 (en) 2024-04-01
US20190153079A1 (en) 2019-05-23
JP2019513726A (ja) 2019-05-30
CR20180529A (es) 2019-03-21
WO2017176651A1 (en) 2017-10-12
US11851482B2 (en) 2023-12-26
IL262010B (en) 2022-09-01
PE20190209A1 (es) 2019-02-07
CA3019332A1 (en) 2017-10-12
KR20190003951A (ko) 2019-01-10
MY194603A (en) 2022-12-06
US20210221877A1 (en) 2021-07-22
IL295288A (en) 2022-10-01
NZ747018A (en) 2025-05-02
AU2017246794B2 (en) 2024-07-04
MA44878A (fr) 2019-03-13
IL311675A (en) 2024-05-01
EA201892225A1 (ru) 2019-09-30
CL2018002810A1 (es) 2019-03-15
JP2023139289A (ja) 2023-10-03
BR112018070357A2 (pt) 2019-01-29
DOP2018000219A (es) 2019-03-31
PH12018502137A1 (en) 2019-09-23
CN109563158B (zh) 2022-08-09
AU2024224000A1 (en) 2024-12-19
US20240228599A1 (en) 2024-07-11
EP3452510A4 (en) 2020-01-15
CN116790614A (zh) 2023-09-22
IL295288B2 (en) 2024-08-01
EP3452510A1 (en) 2019-03-13
KR102673420B1 (ko) 2024-06-07
KR20240096672A (ko) 2024-06-26
JP7326393B2 (ja) 2023-08-15
CN109563158A (zh) 2019-04-02
JP6967528B2 (ja) 2021-11-17
JP2021191789A (ja) 2021-12-16
CO2018010827A2 (es) 2018-11-22
MX2018012176A (es) 2019-02-07
US10934347B2 (en) 2021-03-02
ECSP18082302A (es) 2019-01-31
AU2017246794A1 (en) 2018-10-25
SG11201808525UA (en) 2018-10-30
MX2023007149A (es) 2023-06-28

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