TN2010000231A1 - Derives de pyrazole servant d'inhibiteurs de 5-lo - Google Patents
Derives de pyrazole servant d'inhibiteurs de 5-loInfo
- Publication number
- TN2010000231A1 TN2010000231A1 TN2010000231A TN2010000231A TN2010000231A1 TN 2010000231 A1 TN2010000231 A1 TN 2010000231A1 TN 2010000231 A TN2010000231 A TN 2010000231A TN 2010000231 A TN2010000231 A TN 2010000231A TN 2010000231 A1 TN2010000231 A1 TN 2010000231A1
- Authority
- TN
- Tunisia
- Prior art keywords
- inhibitors
- pyrazole derivatives
- preceded
- compounds
- formula
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P11/06—Antiasthmatics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
Abstract
La présente invention concerne des composées de formule (I) des précédés pour leur preparation, leur utilisation comme inhibiteurs de 5-lipoxygénase et des compositions pharmaceutiques les concernant.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US423607P | 2007-11-26 | 2007-11-26 | |
US426107P | 2007-11-26 | 2007-11-26 | |
US5549708P | 2008-05-23 | 2008-05-23 | |
PCT/IB2008/054873 WO2009069044A1 (fr) | 2007-11-26 | 2008-11-20 | Dérivés de pyrazole comme inhibiteurs de 5-lo |
Publications (1)
Publication Number | Publication Date |
---|---|
TN2010000231A1 true TN2010000231A1 (fr) | 2011-11-11 |
Family
ID=40568336
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TN2010000231A TN2010000231A1 (fr) | 2007-11-26 | 2010-05-21 | Derives de pyrazole servant d'inhibiteurs de 5-lo |
Country Status (28)
Country | Link |
---|---|
US (1) | US8097733B2 (fr) |
EP (1) | EP2225229A1 (fr) |
JP (1) | JP4718650B2 (fr) |
KR (1) | KR20100072090A (fr) |
CN (1) | CN101918392A (fr) |
AP (1) | AP2010005269A0 (fr) |
AR (1) | AR069743A1 (fr) |
AU (1) | AU2008331199A1 (fr) |
BR (1) | BRPI0819661A2 (fr) |
CA (1) | CA2705729C (fr) |
CL (1) | CL2008003495A1 (fr) |
CO (1) | CO6280402A2 (fr) |
CR (1) | CR11392A (fr) |
DO (1) | DOP2010000155A (fr) |
EA (1) | EA201000703A1 (fr) |
EC (1) | ECSP10010200A (fr) |
IL (1) | IL205602A0 (fr) |
MA (1) | MA31863B1 (fr) |
MX (1) | MX2010004604A (fr) |
NI (1) | NI201000089A (fr) |
PA (1) | PA8805301A1 (fr) |
PE (1) | PE20091069A1 (fr) |
SV (1) | SV2010003579A (fr) |
TN (1) | TN2010000231A1 (fr) |
TW (1) | TW200927098A (fr) |
UY (1) | UY31487A1 (fr) |
WO (1) | WO2009069044A1 (fr) |
ZA (1) | ZA201002758B (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2009248774B2 (en) | 2008-05-23 | 2012-05-31 | Novartis Ag | Derivatives of quinolines and quinoxalines as protein tyrosine kinase inhibitors |
US20110269807A1 (en) * | 2010-04-30 | 2011-11-03 | Allergan, Inc. | Novel treatment for age related macular degeneration and ocular ischemic disease associated with complement activation by targeting 5-lipoxygenase |
WO2011161615A1 (fr) | 2010-06-24 | 2011-12-29 | Ranbaxy Laboratories Limited | Inhibiteurs de la 5-lipoxygénase |
AU2014298959B2 (en) | 2013-07-29 | 2018-04-05 | Merck Patent Gmbh | 1,3-disubstituted cyclopentane derivatives |
GB201403605D0 (en) * | 2014-02-28 | 2014-04-16 | Mologic Ltd | Monitoring inflammation status |
US11008339B2 (en) | 2015-05-18 | 2021-05-18 | Shenyang Sinochem Agrochemicals R&D Co., Ltd. | Substituted pyrazole compounds containing pyrimidine and preparation method and use thereof |
CN111825678A (zh) * | 2020-06-05 | 2020-10-27 | 连庆泉 | 一种卡马替尼的制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5254581A (en) * | 1990-06-21 | 1993-10-19 | Imperial Chemical Industries Plc | Pyran derivatives and their use as inhibitors of 5-lipoxygenase |
IE913866A1 (en) * | 1990-11-28 | 1992-06-03 | Ici Plc | Aryl derivatives |
US5272173A (en) * | 1990-11-28 | 1993-12-21 | Imperial Chemical Industries Plc | 5-lipoxygenase inhibitors |
GB9300894D0 (en) * | 1992-02-07 | 1993-03-10 | Zeneca Ltd | Oxime derivatives |
US5883106A (en) * | 1994-10-18 | 1999-03-16 | Pfizer Inc. | 5-lipoxygenase inhibitors |
SK281577B6 (sk) * | 1994-10-18 | 2001-05-10 | Pfizer Inc. | Heterocyklické zlúčeniny a farmaceutický prostriedok na ich báze |
JP3400392B2 (ja) * | 1994-10-18 | 2003-04-28 | ファイザー製薬株式会社 | 5−リポキシゲナーゼ阻害剤及び新規医薬組成物 |
US6063928A (en) * | 1994-10-18 | 2000-05-16 | Pfizer Inc | 5-lipoxygenase inhibitors |
US6239285B1 (en) * | 1998-02-06 | 2001-05-29 | Pfizer Inc | Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems |
MX2008009475A (es) * | 2006-01-23 | 2008-10-20 | Amira Pharmaceuticals Inc | Inhibidores triciclicos de 5-lipoxigenasa. |
EP1834953A1 (fr) * | 2006-03-14 | 2007-09-19 | Ranbaxy Laboratories Limited | Dérivés de tetrahydropyrane comme Inhibiteurs de la 5- lipoxygénase |
RS20090211A (en) * | 2006-11-27 | 2010-10-31 | Pfizer Products Inc. | Pyrazole analogs |
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2008
- 2008-11-20 EP EP08853504A patent/EP2225229A1/fr not_active Withdrawn
- 2008-11-20 KR KR1020107011376A patent/KR20100072090A/ko not_active Application Discontinuation
- 2008-11-20 WO PCT/IB2008/054873 patent/WO2009069044A1/fr active Application Filing
- 2008-11-20 CN CN2008801178682A patent/CN101918392A/zh active Pending
- 2008-11-20 AP AP2010005269A patent/AP2010005269A0/en unknown
- 2008-11-20 MX MX2010004604A patent/MX2010004604A/es not_active Application Discontinuation
- 2008-11-20 AU AU2008331199A patent/AU2008331199A1/en not_active Abandoned
- 2008-11-20 EA EA201000703A patent/EA201000703A1/ru unknown
- 2008-11-20 BR BRPI0819661A patent/BRPI0819661A2/pt not_active IP Right Cessation
- 2008-11-20 JP JP2010535484A patent/JP4718650B2/ja not_active Expired - Fee Related
- 2008-11-20 CA CA2705729A patent/CA2705729C/fr not_active Expired - Fee Related
- 2008-11-24 US US12/276,779 patent/US8097733B2/en not_active Expired - Fee Related
- 2008-11-24 CL CL2008003495A patent/CL2008003495A1/es unknown
- 2008-11-25 TW TW097145472A patent/TW200927098A/zh unknown
- 2008-11-25 UY UY31487A patent/UY31487A1/es not_active Application Discontinuation
- 2008-11-25 PE PE2008001974A patent/PE20091069A1/es not_active Application Discontinuation
- 2008-11-26 PA PA20088805301A patent/PA8805301A1/es unknown
- 2008-11-26 AR ARP080105131A patent/AR069743A1/es not_active Application Discontinuation
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2010
- 2010-04-20 ZA ZA2010/02758A patent/ZA201002758B/en unknown
- 2010-04-26 CR CR11392A patent/CR11392A/es not_active Application Discontinuation
- 2010-05-06 IL IL205602A patent/IL205602A0/en unknown
- 2010-05-21 TN TN2010000231A patent/TN2010000231A1/fr unknown
- 2010-05-24 DO DO2010000155A patent/DOP2010000155A/es unknown
- 2010-05-25 NI NI201000089A patent/NI201000089A/es unknown
- 2010-05-26 EC EC2010010200A patent/ECSP10010200A/es unknown
- 2010-05-26 SV SV2010003579A patent/SV2010003579A/es not_active Application Discontinuation
- 2010-05-26 MA MA32869A patent/MA31863B1/fr unknown
- 2010-05-26 CO CO10063358A patent/CO6280402A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
TW200927098A (en) | 2009-07-01 |
JP4718650B2 (ja) | 2011-07-06 |
EA201000703A1 (ru) | 2010-12-30 |
MA31863B1 (fr) | 2010-11-01 |
NI201000089A (es) | 2010-10-05 |
CA2705729C (fr) | 2012-09-18 |
PE20091069A1 (es) | 2009-07-19 |
BRPI0819661A2 (pt) | 2019-09-24 |
CL2008003495A1 (es) | 2010-03-12 |
CA2705729A1 (fr) | 2009-06-04 |
AR069743A1 (es) | 2010-02-17 |
DOP2010000155A (es) | 2010-07-15 |
US8097733B2 (en) | 2012-01-17 |
ZA201002758B (en) | 2011-06-29 |
CR11392A (es) | 2010-05-28 |
IL205602A0 (en) | 2010-11-30 |
CO6280402A2 (es) | 2011-05-20 |
ECSP10010200A (es) | 2010-06-29 |
PA8805301A1 (es) | 2009-06-23 |
UY31487A1 (es) | 2009-07-17 |
KR20100072090A (ko) | 2010-06-29 |
MX2010004604A (es) | 2010-08-04 |
EP2225229A1 (fr) | 2010-09-08 |
SV2010003579A (es) | 2011-03-23 |
JP2011504514A (ja) | 2011-02-10 |
CN101918392A (zh) | 2010-12-15 |
WO2009069044A1 (fr) | 2009-06-04 |
US20090227634A1 (en) | 2009-09-10 |
AU2008331199A1 (en) | 2009-06-04 |
AP2010005269A0 (en) | 2010-06-30 |
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