SV1998000148A - Arilpiperazinas que tienen actividad en el receptor de serotonina 1a ref. x-11334 - Google Patents
Arilpiperazinas que tienen actividad en el receptor de serotonina 1a ref. x-11334Info
- Publication number
- SV1998000148A SV1998000148A SV1998000148A SV1998000148A SV1998000148A SV 1998000148 A SV1998000148 A SV 1998000148A SV 1998000148 A SV1998000148 A SV 1998000148A SV 1998000148 A SV1998000148 A SV 1998000148A SV 1998000148 A SV1998000148 A SV 1998000148A
- Authority
- SV
- El Salvador
- Prior art keywords
- serotonine
- arylpiperazines
- ref
- receiver
- activity
- Prior art date
Links
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 title 1
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229960002715 nicotine Drugs 0.000 abstract 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
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- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
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- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
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- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
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Abstract
LA PRESENTE INVENCIÓN SE RELACIONA CON UNA SERIE DE COMPUESTOS DE ARILPIPERAZINA SON PRODUCTOS FARMACÉUTICOS EFICACES PARA EL TRATAMIENTO DE TRASTORNOS RELACIONADOS O QUE SE VEN AFECTADOS POR EL RECEPTOR 1A DE LA SEROTONINA, LOS COMPUESTOS SON ANTAGONISTAS ESPECIALMENTE EFICACES SOBRE ESTE RECEPTOR Y SON ESPECIALMENTE ÚTILES PARA ALIVIAR LOS SÍNTOMAS DE LA PRIVACIÓN DEL CONSUMO DE LA NICOTINA Y DEL TABACO
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US6972297P | 1997-12-16 | 1997-12-16 | |
US6979197P | 1997-12-16 | 1997-12-16 | |
US8958998P | 1998-06-17 | 1998-06-17 |
Publications (1)
Publication Number | Publication Date |
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SV1998000148A true SV1998000148A (es) | 1999-08-18 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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SV1998000148A SV1998000148A (es) | 1997-12-16 | 1998-12-15 | Arilpiperazinas que tienen actividad en el receptor de serotonina 1a ref. x-11334 |
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US (9) | US6239135B1 (es) |
EP (2) | EP0924205B1 (es) |
JP (2) | JP2002508364A (es) |
KR (1) | KR100539651B1 (es) |
CN (2) | CN1227241C (es) |
AR (1) | AR017864A1 (es) |
AT (1) | ATE296296T1 (es) |
AU (1) | AU747040B2 (es) |
BR (1) | BR9814280A (es) |
CA (2) | CA2506802A1 (es) |
CO (1) | CO4980859A1 (es) |
DE (1) | DE69830297T2 (es) |
DK (1) | DK0924205T3 (es) |
EA (1) | EA003703B1 (es) |
EG (1) | EG23983A (es) |
ES (1) | ES2244036T3 (es) |
HK (2) | HK1020732A1 (es) |
HR (1) | HRP20000406B1 (es) |
HU (1) | HU226409B1 (es) |
ID (1) | ID26930A (es) |
IL (3) | IL136723A0 (es) |
MY (1) | MY125868A (es) |
NO (1) | NO317098B1 (es) |
NZ (1) | NZ505220A (es) |
PE (1) | PE20000134A1 (es) |
PL (1) | PL193428B1 (es) |
PT (1) | PT924205E (es) |
SV (1) | SV1998000148A (es) |
TR (1) | TR200001727T2 (es) |
TW (1) | TW520366B (es) |
UA (1) | UA66370C2 (es) |
WO (1) | WO1999031077A1 (es) |
ZA (1) | ZA9811473B (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA66370C2 (en) * | 1997-12-16 | 2004-05-17 | Lilly Co Eli | Arylpiperazines having activity to setotonin 1 receptors |
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1998
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